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UNC Lineberger Comprehensive Cancer Center

417 clinical trials · Sponsor

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RecordFirmDate
LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations (NCT01726738)UNC Lineberger Comprehensive Cancer Center2013-04-04
Assessment of Ability of Breath Hold for Left-sided Breast Cancer Radiation Therapy to Reduce Side Effects to Heart (NCT01849614)UNC Lineberger Comprehensive Cancer Center2013-03-01
PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1) (NCT01800032)UNC Lineberger Comprehensive Cancer Center2013-01-16
Metformin for the Treatment of Endometrial Hyperplasia (NCT01685762)UNC Lineberger Comprehensive Cancer Center2013-01-10
Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Known Breast Lesions (NCT01773850)UNC Lineberger Comprehensive Cancer Center2013-01-01
Stereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR) (NCT01573702)UNC Lineberger Comprehensive Cancer Center2012-12-11
Predicting Tolerance to Radiation Therapy in Older Adults With Cancer (NCT01752751)UNC Lineberger Comprehensive Cancer Center2012-11-01
Clinical Cohort of Lymphoma Patients in Malawi (NCT02835911)UNC Lineberger Comprehensive Cancer Center2012-11-01
Hybrid PET/MR in the Therapy of Cervical Cancer (NCT01759355)UNC Lineberger Comprehensive Cancer Center2012-10-01
Feasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy (NCT01789983)UNC Lineberger Comprehensive Cancer Center2012-10-01
PET/MRI as a Predictor of Response to Pre-op Chemoradiation in Resectable Rectal Cancer: a Pilot Study (NCT01751516)UNC Lineberger Comprehensive Cancer Center2012-10-01
Imaging Correlates of Renal Cell Carcinoma Biological Features (NCT01665703)UNC Lineberger Comprehensive Cancer Center2012-08-01
Positron Emission Tomography (PET) Study for Staging of Muscle Invasive Bladder Cancer (NCT01655745)UNC Lineberger Comprehensive Cancer Center2012-07-24
Study of Outcomes After Surgery/Treatment to Treat Bladder Cancer (NCT01776138)UNC Lineberger Comprehensive Cancer Center2012-07-23
Finding Predictors of Side Effects to Chemoradiation Treatment in Elderly Patients With Head and Neck Cancer (NCT01688323)UNC Lineberger Comprehensive Cancer Center2012-07-01
Lenalidomide as Consolidation and Maintenance in Adults >/= 60 Years of Age With AML Following Standard Induction (NCT01578954)UNC Lineberger Comprehensive Cancer Center2012-06-28
Patient Preferences for Breast Reconstruction After Mastectomy (NCT01488357)UNC Lineberger Comprehensive Cancer Center2012-06-01
Multimodality Risk Adapted Tx Including Induction Chemo for SCCHN Amenable to Transoral Surgery (NCT01612351)UNC Lineberger Comprehensive Cancer Center2012-06-01
Cardiovascular Risk and Preventive Care in Prostate Cancer Patients Receiving Radiation and Hormone Therapy (NCT02003417)UNC Lineberger Comprehensive Cancer Center2012-06-01
BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer (NCT01571024)UNC Lineberger Comprehensive Cancer Center2012-05-01
Study of Vorinostat With Doxil and Bortezomib for Patients With Relapsed/Refractory Multiple Myeloma (NCT01492881)UNC Lineberger Comprehensive Cancer Center2012-04-01
Induction Chemo w/ABVD Followed by Brentuximab Vedotin Consolidation in Newly Diagnosed, Non-Bulky Stage I/II Hodgkin Lymphoma (NCT01578967)UNC Lineberger Comprehensive Cancer Center2012-04-01
Crossover Evaluation of Effect of Atorvastatin on PK of Irinotecan in CRC Patients Receiving FOLFIRI (NCT01605344)UNC Lineberger Comprehensive Cancer Center2012-04-01
Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL (NCT03016377)UNC Lineberger Comprehensive Cancer Center2012-03-22
De-intensification of Radiation & Chemotherapy in Low-Risk Human Papillomavirus-related Oropharyngeal Squamous Cell Ca (NCT01530997)UNC Lineberger Comprehensive Cancer Center2012-02-07
Induction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck (NCT01412229)UNC Lineberger Comprehensive Cancer Center2012-02-01
FOLFIRINOX for Unresectable Locally Advanced and Borderline Resectable Pancreatic Cancer (NCT01688336)UNC Lineberger Comprehensive Cancer Center2012-01-01
Defining the Triple Negative Breast Cancer Kinome Response to GSK1120212 (NCT01467310)UNC Lineberger Comprehensive Cancer Center2012-01-01
Circulating Tumor Cells in Solid Tumors (NCT03161821)UNC Lineberger Comprehensive Cancer Center2011-12-09
Everolimus and Pasireotide (SOM230) in Patients With Advanced or Metastatic Hepatocellular Carcinoma (NCT01488487)UNC Lineberger Comprehensive Cancer Center2011-12-01
Selective IMRT for Locally Advanced Head and Neck Carcinoma With Concurrent Panitumumab (NCT01312493)UNC Lineberger Comprehensive Cancer Center2011-12-01
Administration of T Lymphocytes for Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma (CART CD30) (NCT01316146)UNC Lineberger Comprehensive Cancer Center2011-10-03
Development of a Tumor Molecular Analyses Program and Its Use to Support Treatment Decisions (NCT01457196)UNC Lineberger Comprehensive Cancer Center2011-09-01
A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases (NCT01305941)UNC Lineberger Comprehensive Cancer Center2011-09-01
Study of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast Cancer (NCT01300962)UNC Lineberger Comprehensive Cancer Center2011-08-01
Neoadjuvant Pazopanib in Renal Cell Carcinoma (NCT01361113)UNC Lineberger Comprehensive Cancer Center2011-06-01
Ofatumumab In Older Patients With Untreated Low Or Intermediate Risk Indolent B-Cell Lymphomas (NCT01263418)UNC Lineberger Comprehensive Cancer Center2011-06-01
Bavituximab Plus Carbo and Pemetrexed in Chemo-Naive Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Subjects (NCT01323062)UNC Lineberger Comprehensive Cancer Center2011-05-01
Preoperative Window Study of Metformin for the Treatment of Endometrial Cancer (NCT01911247)UNC Lineberger Comprehensive Cancer Center2011-05-01
Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer (NCT01298570)UNC Lineberger Comprehensive Cancer Center2011-04-07
Bendamustine + Rituximab in Older Patients With Previously Untreated Diffuse Large B-cell Lymphoma (NCT01234467)UNC Lineberger Comprehensive Cancer Center2011-03-01
Retinal Oxygen Function After Radiation Therapy (NCT02043470)UNC Lineberger Comprehensive Cancer Center2011-03-01
Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease (NCT00448201)UNC Lineberger Comprehensive Cancer Center2011-01-07
North Carolina Prostate Cancer Comparative Effectiveness & Survivorship Study (NC ProCESS) (NCT02564120)UNC Lineberger Comprehensive Cancer Center2011-01-01
Pilot Study to Evaluate Individualized Choice of Antidepressants in Patients With Cancer (NCT01725048)UNC Lineberger Comprehensive Cancer Center2011-01-01
Pazopanib In Stage IIIB/IV NSCLC Lung Cancer After Progression on First Line Therapy Containing Bevacizumab (NCT01262820)UNC Lineberger Comprehensive Cancer Center2010-12-01
Study of the P16 Gene as a Predictor of Myelosuppression in Breast Cancer Patients (NCT01305954)UNC Lineberger Comprehensive Cancer Center2010-12-01
PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias (NCT01169012)UNC Lineberger Comprehensive Cancer Center2010-09-01
Use of Palliative Performance and Symptom Distress Scales in Older Patients With Advanced Ovarian Cancer (NCT01175967)UNC Lineberger Comprehensive Cancer Center2010-06-01
Trisenox® in Women With Metastatic Endometrial Cancer (NCT01184053)UNC Lineberger Comprehensive Cancer Center2010-03-01
Carboplatin, Pemetrexed Disodium, and Bevacizumab for Patients With Stage III or IV Non-Small Cell Lung Cancer Who Are Light/Never Smokers (NCT01344824)UNC Lineberger Comprehensive Cancer Center2010-03-01
Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy (NCT01164215)UNC Lineberger Comprehensive Cancer Center2010-02-01
Biomarkers in Blood Samples From Older Breast Cancer Survivors (NCT01138345)UNC Lineberger Comprehensive Cancer Center2010-01-01
Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma (NCT01204450)UNC Lineberger Comprehensive Cancer Center2009-11-01
Registry of Older Patients With Cancer (NCT01137825)UNC Lineberger Comprehensive Cancer Center2009-09-01
Sorafenib Tosylate and Chemoembolization With Doxorubicin Hydrochloride and Mitomycin in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery (NCT01011010)UNC Lineberger Comprehensive Cancer Center2009-07-22
Carboplatin, Ixabepilone, and Cetuximab in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Untreated With Chemotherapy (NCT00998101)UNC Lineberger Comprehensive Cancer Center2009-07-01
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer (NCT01137643)UNC Lineberger Comprehensive Cancer Center2009-07-01
Safety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastases (NCT01528878)UNC Lineberger Comprehensive Cancer Center2009-04-01
Biomarkers Related to Thrombosis in Patients With Newly Diagnosed Multiple Myeloma Receiving Chemotherapy (NCT01132833)UNC Lineberger Comprehensive Cancer Center2008-12-01
Vorinostat, Bortezomib, and Doxorubicin Hydrochloride Liposome in Treating Patients With Relapsed or Refractory Multiple Myeloma (NCT00744354)UNC Lineberger Comprehensive Cancer Center2008-10-01
Digital Breast Tomosynthesis Preference Study (NCT00776126)UNC Lineberger Comprehensive Cancer Center2008-10-01
Sorafenib in Treating Patients With Locally Advanced or Metastatic Liver Cancer and Cirrhosis (NCT00767468)UNC Lineberger Comprehensive Cancer Center2008-10-01
Studying Blood Samples From Women With Breast Cancer or Ductal Carcinoma In Situ Who Are Receiving Tamoxifen (NCT00764322)UNC Lineberger Comprehensive Cancer Center2008-06-18
Radiation Induced Cardiopulmonary Injury in Humans (NCT02259452)UNC Lineberger Comprehensive Cancer Center2008-06-01
Everolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Tumors That Did Not Respond to Treatment (NCT00610948)UNC Lineberger Comprehensive Cancer Center2008-03-01
Clofarabine and Gemtuzumab in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (NCT00577694)UNC Lineberger Comprehensive Cancer Center2007-11-01
Sorafenib Combined With Cisplatin and Etoposide or Carboplatin and Pemetrexed in Treating Patients With Metastatic Solid Tumors (NCT00573690)UNC Lineberger Comprehensive Cancer Center2007-09-01
Ph II of Vinflunine and Cetuximab in Second Line Treatment of NSCLC (NCT00519831)UNC Lineberger Comprehensive Cancer Center2007-08-01
Visibility of Lesion Characteristics With Phase Contrast Mammography (NCT00467727)UNC Lineberger Comprehensive Cancer Center2007-04-01
Efalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous Steroids (NCT00489216)UNC Lineberger Comprehensive Cancer Center2006-12-01
Sorafenib in Treating Patients Undergoing Surgery for Stage II, Stage III, or Stage IV Kidney Cancer (NCT00405366)UNC Lineberger Comprehensive Cancer Center2006-11-01
Oxaliplatin, Capecitabine, and Cetuximab in Treating Patients With Advanced Liver Cancer (NCT00483405)UNC Lineberger Comprehensive Cancer Center2006-10-01
Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine in Treating Patients With Advanced Metastatic Solid Tumors (NCT00307255)UNC Lineberger Comprehensive Cancer Center2006-08-01
Vinflunine and Erlotinib or Pemetrexed in Treating Patients With Unresectable or Metastatic Solid Tumors (NCT00320073)UNC Lineberger Comprehensive Cancer Center2006-08-01
Bortezomib, Rituximab, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed or Refractory Low-Grade, Follicular, or Mantle Cell Non-Hodgkin's Lymphoma (NCT00334438)UNC Lineberger Comprehensive Cancer Center2006-07-01
Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer (NCT00380029)UNC Lineberger Comprehensive Cancer Center2006-05-01
Study of Abraxane and Carboplatin to Treat Small Cell Lung Cancer (NCT00454324)UNC Lineberger Comprehensive Cancer Center2006-04-01
Lapatinib and Radiation Therapy in Treating Patients With Locally Recurrent or Chemotherapy-Refractory Locally Advanced or Metastatic Breast Cancer (NCT00379509)UNC Lineberger Comprehensive Cancer Center2006-04-01
Ph II Gemcitabine, Erlotinib, and Gemcitabine With Erlotinib/Elderly Patients W/ IIIB/IV NSCLC (NCT00283244)UNC Lineberger Comprehensive Cancer Center2006-03-01
Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia (NCT00499759)UNC Lineberger Comprehensive Cancer Center2006-02-01
Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy (NCT00486304)UNC Lineberger Comprehensive Cancer Center2006-02-01
Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer (NCT00280150)UNC Lineberger Comprehensive Cancer Center2006-01-01
Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast Cancer (NCT00266110)UNC Lineberger Comprehensive Cancer Center2005-12-01
Cetuximab + / - Carboplatin for Estrogen Receptor-Negative, Progesterone Receptor-Negative Metastatic Breast Cancer (NCT00232505)UNC Lineberger Comprehensive Cancer Center2005-11-01
Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen (NCT00448357)UNC Lineberger Comprehensive Cancer Center2005-10-01
Lapatinib in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy (NCT00246753)UNC Lineberger Comprehensive Cancer Center2005-10-01
Erlotinib in Treating Patients With Progressive Glioblastoma Multiforme (NCT00227032)UNC Lineberger Comprehensive Cancer Center2005-09-01
Docetaxel, Androgen Ablation, and External-Beam Radiation Therapy in Patients With High-Risk Localized Prostate Cancer (NCT00225420)UNC Lineberger Comprehensive Cancer Center2005-08-01
Effect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast Cancer (NCT00719173)UNC Lineberger Comprehensive Cancer Center2005-08-01
Octreotide in Treating Patients With Locally Advanced or Metastatic Liver Cancer (NCT00257426)UNC Lineberger Comprehensive Cancer Center2005-07-01
Fludeoxyglucose F 18-PET Imaging for Early Detection of Residual Disease in Patients Undergoing Radiofrequency Ablation of Liver Metastases From Colorectal Cancer (NCT00499395)UNC Lineberger Comprehensive Cancer Center2005-07-01
Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer (NCT00280748)UNC Lineberger Comprehensive Cancer Center2005-05-01
Using Magnetic Resonance Spectroscopy With MRI to Non-invasively Determine Breast Cancer Extent of Disease (NCT00312637)UNC Lineberger Comprehensive Cancer Center2005-03-01
Irinotecan, Cisplatin, and Radiation Therapy With or Without Celecoxib in Treating Patients With Stage II, Stage III, or Stage IV Esophageal Cancer (NCT00520091)UNC Lineberger Comprehensive Cancer Center2005-03-01
Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Metastatic Solid Tumors (NCT00520000)UNC Lineberger Comprehensive Cancer Center2004-12-01
Mammography Reminders for Encouraging Women to Undergo Regular Mammography Screenings for Breast Cancer (NCT01148875)UNC Lineberger Comprehensive Cancer Center2004-09-01
Oxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metastatic Pancreatic Cancer or Biliary Tract Cancer (NCT00266097)UNC Lineberger Comprehensive Cancer Center2004-08-01
Ph II Adjuvant Carboplatin/Docetaxel in Curatively Resected Stage I-IIIA NSCLC (NCT00280735)UNC Lineberger Comprehensive Cancer Center2004-05-01
Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women (NCT00099008)UNC Lineberger Comprehensive Cancer Center2004-03-01
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