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UNC Lineberger Comprehensive Cancer Center

417 clinical trials · Sponsor

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RecordFirmDate
Trial of a Personalized and Adaptive Neoantigen Dose-Adjusted Vaccine Concurrently With Pembrolizumab (NCT04266730)UNC Lineberger Comprehensive Cancer Center2027-05-20
Optimization of Dietary Adherence in a Mobile Weight Loss Intervention (NCT07582536)UNC Lineberger Comprehensive Cancer Center2027-03-01
Evaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts (NCT06026098)UNC Lineberger Comprehensive Cancer Center2026-10-01
Incorporating Biometric Data for Patients Receiving Concurrent Chemotherapy & RT (NCT05937659)UNC Lineberger Comprehensive Cancer Center2026-09-15
Virtual Testis Cancer Lay Support and Survivorship Aim 2 (NCT06702592)UNC Lineberger Comprehensive Cancer Center2026-09-01
Uniting Trusted Community Messengers to Improve Access to Cervical Cancer Screening in Rural North Carolina (NCT07294066)UNC Lineberger Comprehensive Cancer Center2026-09-01
NeoAdjuvant, Spare-Adjuvant (NASA) in Stage IIIB-IV (M1a) Melanoma (NCT07740941)UNC Lineberger Comprehensive Cancer Center2026-08-05
Effects of Infusion Timing on Treatment Response in Solid Tumors (NCT07630168)UNC Lineberger Comprehensive Cancer Center2026-08-01
Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer (NCT07078838)UNC Lineberger Comprehensive Cancer Center2026-08-01
Overcoming Barriers to Uptake of Cascade Screening (NCT07304063)UNC Lineberger Comprehensive Cancer Center2026-07-01
Dara-RVd Induction for Newly Diagnosed Multiple Myeloma With Autologous Stem Cell Transplantation (NCT06348147)UNC Lineberger Comprehensive Cancer Center2026-07-01
SURGIMEDIA: Utilization of Multimedia for Enhanced Surgical Consent (NCT07494994)UNC Lineberger Comprehensive Cancer Center2026-07-01
Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML (NCT07605949)UNC Lineberger Comprehensive Cancer Center2026-07-01
Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease (NCT07685938)UNC Lineberger Comprehensive Cancer Center2026-07-01
The PharmFIT Study (NCT06656936)UNC Lineberger Comprehensive Cancer Center2026-07-01
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology (NCT07463833)UNC Lineberger Comprehensive Cancer Center2026-06-22
Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in Women Living With HIV (NCT07624123)UNC Lineberger Comprehensive Cancer Center2026-06-01
C-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the United States (NCT07520188)UNC Lineberger Comprehensive Cancer Center2026-06-01
H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC) (NCT07484139)UNC Lineberger Comprehensive Cancer Center2026-06-01
Olomorasib + Pembrolizumab KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or Metastatic NSCLC (NCT07639242)UNC Lineberger Comprehensive Cancer Center2026-06-01
Dietary Cysteine and Methionine Deprivation (CMD) in Glioma Patients (NCT07553520)UNC Lineberger Comprehensive Cancer Center2026-05-01
Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL) (NCT07634653)UNC Lineberger Comprehensive Cancer Center2026-05-01
Tirzepatide in Obesity-Driven Endometrial Cancer (NCT07065552)UNC Lineberger Comprehensive Cancer Center2026-04-27
Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes (NCT07599462)UNC Lineberger Comprehensive Cancer Center2026-04-24
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome (NCT07296861)UNC Lineberger Comprehensive Cancer Center2026-04-16
Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer (NCT07276880)UNC Lineberger Comprehensive Cancer Center2026-03-17
Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors (NCT07479199)UNC Lineberger Comprehensive Cancer Center2026-03-16
PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease (NCT07069595)UNC Lineberger Comprehensive Cancer Center2026-02-26
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies (NCT07340541)UNC Lineberger Comprehensive Cancer Center2026-02-16
Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in Women With HIV (NCT07428330)UNC Lineberger Comprehensive Cancer Center2026-02-03
Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia (NCT07278557)UNC Lineberger Comprehensive Cancer Center2026-01-28
Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise (NCT07313306)UNC Lineberger Comprehensive Cancer Center2025-12-15
Medically Tailored Meals for Kids (NCT06814795)UNC Lineberger Comprehensive Cancer Center2025-11-25
Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging (NCT07225114)UNC Lineberger Comprehensive Cancer Center2025-11-04
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors (NCT06848491)UNC Lineberger Comprehensive Cancer Center2025-10-27
Consumer Perceptions of Alcoholic Beverages (NCT07226271)UNC Lineberger Comprehensive Cancer Center2025-10-10
Dissemination of BREASTChoice AIM1-B (NCT07396766)UNC Lineberger Comprehensive Cancer Center2025-10-01
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults (NCT07116837)UNC Lineberger Comprehensive Cancer Center2025-10-01
Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer (NCT07025785)UNC Lineberger Comprehensive Cancer Center2025-08-22
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer (NCT06727773)UNC Lineberger Comprehensive Cancer Center2025-08-19
Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia (NCT06276946)UNC Lineberger Comprehensive Cancer Center2025-08-08
PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival (NCT06896162)UNC Lineberger Comprehensive Cancer Center2025-06-27
mPATH-Cloud for Colorectal Cancer Screening (NCT06441487)UNC Lineberger Comprehensive Cancer Center2025-06-24
XL092 and Cemiplimab in BRAF WT Thyroid Cancer (NCT06902376)UNC Lineberger Comprehensive Cancer Center2025-06-03
Combating Cancer-Related Fatigue: A Personalized Supportive Care Program (NCT06860880)UNC Lineberger Comprehensive Cancer Center2025-06-03
Implementation of an Oral Chemotherapy Adherence Intervention (NCT06989489)UNC Lineberger Comprehensive Cancer Center2025-05-28
Designing Visual Tools to Enhance Cancer Surgeon Decision-making (NCT06965192)UNC Lineberger Comprehensive Cancer Center2025-04-24
Piloting a Reinforcement Learning Tool for Individually Tailoring Just-in-time Adaptive Interventions (NCT05751993)UNC Lineberger Comprehensive Cancer Center2025-04-12
Digital Art Therapy for Young Cancer Survivors (NCT06789666)UNC Lineberger Comprehensive Cancer Center2025-04-07
Social Media Posts About Cancer: Five Timepoints (NCT07588607)UNC Lineberger Comprehensive Cancer Center2025-03-31
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients (NCT06878547)UNC Lineberger Comprehensive Cancer Center2025-03-07
Effectiveness of Central Oncology Navigation and the Use of an ORN (NCT06618274)UNC Lineberger Comprehensive Cancer Center2025-03-03
Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST) (NCT06902311)UNC Lineberger Comprehensive Cancer Center2025-02-19
Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel (NCT06483555)UNC Lineberger Comprehensive Cancer Center2025-02-06
Rehabilitation Outcomes Study (NCT06674889)UNC Lineberger Comprehensive Cancer Center2025-01-21
Immune Reconstitution Monitoring and Pneumococcal Vaccination in Patients Treated With CAR-T Cells (NCT07071909)UNC Lineberger Comprehensive Cancer Center2025-01-20
Promoting Resilience in Women With Breast Cancer (PRISM -MBC) (NCT06855654)UNC Lineberger Comprehensive Cancer Center2025-01-01
Streamlined Resin Y90 Radiation Segmentectomy for Small HCC (NCT06618300)UNC Lineberger Comprehensive Cancer Center2024-11-06
VisR for Noninvasively Interrogating Stromal Collagen Organization as a Breast Cancer Biomarker: Evaluation of Compression in Control Subjects (NCT06547034)UNC Lineberger Comprehensive Cancer Center2024-10-16
BREAST Choice Decision Tool R21 - AIM2 (NCT06817226)UNC Lineberger Comprehensive Cancer Center2024-10-10
Multimedia Aid for Genetic Testing in Gynecologic Oncology (NCT07084168)UNC Lineberger Comprehensive Cancer Center2024-10-10
A Novel Approach Utilizing Organ Specific Age Proteomics (NCT06789653)UNC Lineberger Comprehensive Cancer Center2024-10-10
Effective Ads for Quitting Smoking (NCT06485479)UNC Lineberger Comprehensive Cancer Center2024-09-05
Physical Activity Centers Empowerment (NCT06411756)UNC Lineberger Comprehensive Cancer Center2024-08-14
Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking (NCT06546618)UNC Lineberger Comprehensive Cancer Center2024-08-14
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells (NCT06305299)UNC Lineberger Comprehensive Cancer Center2024-07-29
Little Cigar and Cigarillo Warnings for Youth (NCT06413797)UNC Lineberger Comprehensive Cancer Center2024-07-18
Autologous CAR-T Cells Targeting B7-H3 in PDAC (NCT06158139)UNC Lineberger Comprehensive Cancer Center2024-07-18
DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics (NCT06296368)UNC Lineberger Comprehensive Cancer Center2024-06-21
Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya (NCT06263582)UNC Lineberger Comprehensive Cancer Center2024-05-29
Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment (NCT04743674)UNC Lineberger Comprehensive Cancer Center2024-05-03
ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells (NCT06090864)UNC Lineberger Comprehensive Cancer Center2024-04-25
UNC Metastatic Cancer Radiation Therapy Registry (NCT06306924)UNC Lineberger Comprehensive Cancer Center2024-04-21
Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC (NCT06096038)UNC Lineberger Comprehensive Cancer Center2024-04-05
Abequolixron (RGX-104) and Durvalumab in Lung Cancer (NCT05911308)UNC Lineberger Comprehensive Cancer Center2024-04-01
Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya (NCT06165614)UNC Lineberger Comprehensive Cancer Center2024-03-04
Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors (NCT06171945)UNC Lineberger Comprehensive Cancer Center2024-03-01
18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy (NCT05483023)UNC Lineberger Comprehensive Cancer Center2024-02-15
Impact of E-Cigarette Prevention Messages on Adolescents (NCT05985538)UNC Lineberger Comprehensive Cancer Center2024-02-05
Promoting CT Engagement for Pancreatic Cancer With App (NCT06252545)UNC Lineberger Comprehensive Cancer Center2024-02-02
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study (NCT04700527)UNC Lineberger Comprehensive Cancer Center2023-12-15
Isa-Pom-Dex in Elderly/Frail Subjects With RRMM (NCT05911321)UNC Lineberger Comprehensive Cancer Center2023-12-05
Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study (NCT07214610)UNC Lineberger Comprehensive Cancer Center2023-11-28
Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS) (NCT06075316)UNC Lineberger Comprehensive Cancer Center2023-11-14
GRID Therapy for Extremity Soft Tissue Sarcoma (NCT06073067)UNC Lineberger Comprehensive Cancer Center2023-11-09
The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment (NCT06096623)UNC Lineberger Comprehensive Cancer Center2023-11-06
ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer (NCT05542407)UNC Lineberger Comprehensive Cancer Center2023-10-23
Physical Activity and Healthy Eating Among Young Adult Cancer Survivors (NCT05887401)UNC Lineberger Comprehensive Cancer Center2023-10-02
Physical Therapy in Pre-cystectomy Patients (NCT05978570)UNC Lineberger Comprehensive Cancer Center2023-08-27
Brain Slice Explants to Predict Drug Response in Brain Tumors (NCT05978557)UNC Lineberger Comprehensive Cancer Center2023-07-27
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer (NCT05620342)UNC Lineberger Comprehensive Cancer Center2023-06-21
Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs (NCT05849051)UNC Lineberger Comprehensive Cancer Center2023-05-22
enCompass Carolina: A Social Support and Coaching Program for Cancer Caregivers (NCT05828927)UNC Lineberger Comprehensive Cancer Center2023-05-15
Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers (NCT05823740)UNC Lineberger Comprehensive Cancer Center2023-05-01
Intervention to Address Psychosocial Needs Among Socially Disadvantaged Older Adults With Cancer (NCT05828654)UNC Lineberger Comprehensive Cancer Center2023-04-28
5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East Africa (NCT05362955)UNC Lineberger Comprehensive Cancer Center2023-04-26
Kaposi Sarcoma Chemotherapy and Research (KS-CARE) (NCT06480773)UNC Lineberger Comprehensive Cancer Center2023-04-25
Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (NCT05413811)UNC Lineberger Comprehensive Cancer Center2023-03-22
Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies (NCT05743426)UNC Lineberger Comprehensive Cancer Center2023-03-17
Assessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast Cancer (NCT05755347)UNC Lineberger Comprehensive Cancer Center2023-03-17
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