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Shanghai Chest Hospital

192 clinical trials · Sponsor

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Label-free Femtosecond Laser Imaging Combined With the Fast Lung Artificial Intelligence Model for Rapid Intraoperative Diagnosis of Lung Surgical Specimens: A Multicentre, Prospective, Parallel-workflow, Non-inferiority Study. (NCT07681245)Shanghai Chest Hospital2026-07-03
Segmentectomy Versus Lobectomy for Deep Solid-Dominant Early-Stage NSCLC (NCT07698990)Shanghai Chest Hospital2026-07-01
SYHX2011 in Combination With Carboplatin and Enlonstobart as First-Line Therapy for Squamous Non-Small Cell Lung Cancer (NCT07662811)Shanghai Chest Hospital2026-06-01
Sd-RAB for the Diagnosis of PPNs (NCT06719687)Shanghai Chest Hospital2026-06-01
Xuan Yin Ning Plus Bevacizumab for Malignant Pleural Effusion (NCT07670338)Shanghai Chest Hospital2026-06-01
Robotic-Assisted Bronchoscopy-Guided Synchronous Biopsy and Radiofrequency Ablation for Pulmonary Nodules (NCT07545057)Shanghai Chest Hospital2026-05-01
RATS Sleeve Lobectomy After Neo-Chemo-IO for NSCLC (NCT07541521)Shanghai Chest Hospital2026-04-13
Septum-guided Segmentectomy for Deep Early-stage Lung Cancer (SGS2512) (NCT07564557)Shanghai Chest Hospital2026-04-01
Neoadjuvant Adebrelimab Plus CRT for Locally Advanced Thymic Carcinoma (NCT07479628)Shanghai Chest Hospital2026-04-01
Establishment of a Prospective Clinical Cohort of Small Cell Lung Cancer Patients Receiving Radiotherapy-Involved Comprehensive Treatment (NCT07565532)Shanghai Chest Hospital2026-04-01
Vebreltinib Plus Chemotherapy as First-line Treatment for MET-overexpressing NSCLC (NCT07549061)Shanghai Chest Hospital2026-03-30
Downstaging and RATS After Neo-Chemo-IO: Impact on Surgical Outcomes in NSCLC (NCT07528066)Shanghai Chest Hospital2026-03-02
The Efficacy and Safety of ARNI on the Outcome of Advanced Lung Cancer With Concurrent Hypertension (NCT07261098)Shanghai Chest Hospital2026-01-01
Epicardial Adipose Tissue-Targeted DApagliflozin for Reducing Electrical Remodeling in Atrial Fibrillation (NCT07331727)Shanghai Chest Hospital2026-01-01
Renal Denervation Combined With Pulsed Field Ablation to Prevent Recurrence in Persistent Atrial Fibrillation (NCT07320768)Shanghai Chest Hospital2026-01-01
SGLT2 Inhibitors and Survival in Lung Cancer Patients With Diabetes (NCT07272057)Shanghai Chest Hospital2025-12-07
A Study of SHR-A1811 Combined With Adebelimumab as Neoadjuvant Therapy for Resectable HER2-Altered Non-Small Cell Lung Cancer (NCT07281209)Shanghai Chest Hospital2025-12-01
A Study of QL1706 Combined With Chemotherapy Induction on Sequential Immunotherapy Consolidation in Patients With Limited-Stage Small Cell Lung Cancer After Chemoradiotherapy (NCT07091305)Shanghai Chest Hospital2025-10-23
Infiltration Pattern of Locally Advanced ESCC (NCT07567716)Shanghai Chest Hospital2025-10-01
A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC (NCT07058519)Shanghai Chest Hospital2025-09-23
Surufatinib Combined With Chemo Versus Surufatinib in the Treatment of Pulmonary Neuroendocrine Tumors (NCT07357623)Shanghai Chest Hospital2025-09-22
Sleeve Lobectomy Following Neoadjuvant Therapy in NSCLC (NCT07135856)Shanghai Chest Hospital2025-09-01
Clinical Validation Study on the Imaging Efficacy of Mobile 4D CBCT Technology for Peripheral Pulmonary Lesions (NCT07149597)Shanghai Chest Hospital2025-09-01
Novel Thin Bronchoscope Versus Ultrathin Bronchoscope for the Diagnosis of Peripheral Pulmonary Nodules (NCT07135297)Shanghai Chest Hospital2025-09-01
Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation (NCT07122336)Shanghai Chest Hospital2025-07-16
A Study of Contrast-enhanced EBUS in Lung Lesions and Intrathoracic Lymph Nodes (NCT07060378)Shanghai Chest Hospital2025-07-10
RAB Versus Ultrathin Bronchoscopy With VBN in the Diagnosis of PPNs (NCT06962436)Shanghai Chest Hospital2025-07-02
Shanghai Clinical Cohort - Esophageal Cancer (NCT07312526)Shanghai Chest Hospital2025-07-01
A Clinical Study on the Efficacy and Safety of the Combination of Limertinib and Bevacizumab Versus Limertinib as First-line Treatment for NSCLC. (NCT06982924)Shanghai Chest Hospital2025-06-30
Standard-of-care Systemic Therapy With or Without Local Therapy in Patients With Oligoprogressive Non-Small Cell Lung Cancer(NSCLC) (NCT07076693)Shanghai Chest Hospital2025-06-03
Transbronchial MWA for Pulmonary Tumors (NCT06969014)Shanghai Chest Hospital2025-05-12
MWA With or Without Furmonertinib for Early-Stage Non-Small Cell Lung Cancer (NCT06969781)Shanghai Chest Hospital2025-05-01
A Multicenter, Single-arm Phase II Study to Evaluate the Efficacy and Safety of Fulzerasib (IBI351) in Combination With Ivonescimab (AK-112) in First-line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer Patients With KRAS G12C Mutation (NCT06936644)Shanghai Chest Hospital2025-04-30
Cryoablation vs Thoracoscopic Surgery for GGN (NCT06848881)Shanghai Chest Hospital2025-04-20
Resistance Mechanisms and Sequential Treatment Strategies Following First-Line Lorlatinib in ALK-Positive NSCLC (NCT06904547)Shanghai Chest Hospital2025-04-20
GGO-dominant PPLs Diagnosis Using CLE and ssRAB-guided Cryobiopsy (NCT06910046)Shanghai Chest Hospital2025-04-01
EBUS-TTFB vs EBUS-TBNA for Diagnosing Inadequate Lymph Node Specimens Based on MOSE (NCT06913569)Shanghai Chest Hospital2025-04-01
Neoadjuvant Chemotherapy Sequentially Combined with Sintilimab in Resectable EGFR-Mutant NSCLC (NCT06688656)Shanghai Chest Hospital2025-03-31
Intracardiac Echocardiography-Guided Catheter Ablation for Premature Ventricular Contractions Originating From the Papillary Muscles (NCT06898281)Shanghai Chest Hospital2025-03-23
Efficacy of Mavacamten Combined With Radiofrequency Ablation in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (NCT06856265)Shanghai Chest Hospital2025-02-26
Efficacy and Safety of Pulsed Field Ablation in Refractory Mitral Isthmus-dependent Atrial Flutter: Pulsed Field Ablation Vs. Radiofrequency Ablation: a Preliminary Randomized Controlled Study (NCT06850064)Shanghai Chest Hospital2025-02-24
The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer (NCT05798845)Shanghai Chest Hospital2025-02-20
Comparative Efficacy and Safety of Extensive Electro-Anatomical Guided Pulsed Field Ablation Versus Radiofrequency Ablation in Persistent Atrial Fibrillation (NCT06745167)Shanghai Chest Hospital2025-01-01
Pulsed Field Ablation in Three Different Substrate Ablation Strategies for Persistent Atrial Fibrillation (NCT06739512)Shanghai Chest Hospital2024-12-25
Atrial Fibrillation with Heart Failure with Preserved Ejection Fraction: Treatment Strategies-Catheter Ablation Vs. Anti-Atrial Arrhythmia Drugs (NCT06740539)Shanghai Chest Hospital2024-12-16
Efficacy and Safety of Intravenous + Oral Vs. Oral Amiodarone in Preventing Recurrence After Catheter Ablation in Patients with Persistent Atrial Fibrillation (NCT06742866)Shanghai Chest Hospital2024-12-16
A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC (NCT06690671)Shanghai Chest Hospital2024-12-15
Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC (NCT06663306)Shanghai Chest Hospital2024-12-09
Perioperative Tislelizumab for Resectable II-IIIB(N2) KRAS-mutated Nonsquamous Non-small Cell Lung Cancer (NCT06659042)Shanghai Chest Hospital2024-11-20
Perioperative Treatment Outcomes of Early NSCLC (NCT06610240)Shanghai Chest Hospital2024-11-01
A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS) (NCT06709417)Shanghai Chest Hospital2024-11-01
Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin (NCT06698965)Shanghai Chest Hospital2024-10-13
Optimized Posterior Left Atrial Wall Ablation Strategy for PeAF (NCT06633523)Shanghai Chest Hospital2024-10-01
Efficacy and Safety of Combination Therapy of Sintilimab and Chemotherapy With Cryoablation in NSCLC (NCT06483009)Shanghai Chest Hospital2024-10-01
Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients(neoR-TORCH) (NCT06437977)Shanghai Chest Hospital2024-09-12
Assessment the Effectiveness of BTVA in COPD and Ablation in Pulmonary Nodules by Pulmonary MRI (NCT07045532)Shanghai Chest Hospital2024-09-01
Cryoablation with or Without Serplulimab in Treating Patients with Stage I-IIA Non-small Cell Lung Cancer (NCT06580665)Shanghai Chest Hospital2024-09-01
Real-World Assessment of Therapeutic Strategies and Survival Outcomes Following First-Line Tislelizumab Therapy in Advanced Non-Small Cell Lung Cancer (NCT06962449)Shanghai Chest Hospital2024-08-16
Augmented Reality Assisted Lung Nodule Localization: a Multicentered, Prospective, Randomly Controlled, Non-inferiority Trial (NCT06548451)Shanghai Chest Hospital2024-08-15
Trametinib Plus Anlotinib Combined With Tislelizumab in KRAS-mutant NSCLC (NCT06456138)Shanghai Chest Hospital2024-07-01
Neoadjuvant Immunochemotherapy for Adenocarcinoma of the Esophagogastric Junction (NCT06469060)Shanghai Chest Hospital2024-06-19
Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS) (NCT06385730)Shanghai Chest Hospital2024-06-17
A Comparative Study Evaluating the Vein of MArshall Ethanol Infusion Ablation Using an Over-the-wire (OTW) Balloon Versus a microcatHeter in Patients With Atrial Fibrillation (NCT06460831)Shanghai Chest Hospital2024-06-15
Optical Biopsy for Peripheral Pulmonary Lesions (NCT06457087)Shanghai Chest Hospital2024-06-01
Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC (NCT06127303)Shanghai Chest Hospital2024-04-02
Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation (NCT06348381)Shanghai Chest Hospital2024-04-01
Improving Patient-reported Outcomes After Lung Cancer Surgery With Mobile Internet Platform (NCT06483295)Shanghai Chest Hospital2024-03-24
The Novel Special Light for Endotracheal/Bronchial Lesions. (NCT07036614)Shanghai Chest Hospital2024-01-31
Blinded Randomized Controlled Trial of Artificial Intelligence Guided Detection of Intracardiac Thrombus (NCT06206187)Shanghai Chest Hospital2024-01-05
Transthoracic vs Transbronchial Radiofrequency Ablation for Lung Cancer (NCT06503744)Shanghai Chest Hospital2024-01-04
RAE Versus MIE in Patients With Esophageal Cancer After Neoadjuvant Therapy (NCT06012214)Shanghai Chest Hospital2024-01-01
A Multi-center RCT to Evaluate Subsegmental BTVA Treatment for Severe Emphysema (NCT06152107)Shanghai Chest Hospital2024-01-01
Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan (NCT06358222)Shanghai Chest Hospital2023-12-15
Neoadjuvant Adebrelimab Plus Chemotherapy for Resectable ESCC: a Single Arm, Prospective Phase 2 Clinical Trial (NCT06178211)Shanghai Chest Hospital2023-12-01
Glycoprotein in Immunotherapy Response and Efficacy Prediction of Lung Cancer (NCT06730503)Shanghai Chest Hospital2023-10-01
A Randomized Controlled Study of Ablation Pursuing Atrial Fibrillation Termination as a Procedural Endpoint in Patients With Persistent Atrial Fibrillation (NCT05921734)Shanghai Chest Hospital2023-08-01
Pembrolizumab Plus Bevacizumab and Chemotherapy for Non-Squamous NSCLC Patients (NCT05751187)Shanghai Chest Hospital2023-06-27
Application of Mixed Reality Technique for Percutaneous Lung Nodule Localization: A Prospective, Randomized, Controlled Trial (NCT05715996)Shanghai Chest Hospital2023-05-23
A Study of Molecular Residual, Dynamic Monitoring and Recurrence of Stage III Driver Mutated NSCLC (NCT06443684)Shanghai Chest Hospital2023-05-08
Cadonilimab in Patients (Pts) With Advanced Non-small Cell Lung Cancer (NSCLC) (NCT05816499)Shanghai Chest Hospital2023-02-16
Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer (NCT06173986)Shanghai Chest Hospital2023-01-10
Left Atrial Isolation by Catheter Ablation in Persistent Atrial Fibrillation With Severe Atrial Fibrosis (NCT05173779)Shanghai Chest Hospital2023-01-01
Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma (NCT05978193)Shanghai Chest Hospital2023-01-01
PerAF: AF Termination vs Prespecified Ablation (NCT06837441)Shanghai Chest Hospital2023-01-01
Camrelizumab Combined With Neoadjuvant Concurrent Chemoradiotherapy for Resectable Locally Advanced ESCC(NICE-RT) (NCT05650216)Shanghai Chest Hospital2022-12-25
Chemoradiotherapy Following Immunotherapy Plus Chemotherapy for Locally-advanced Esophageal Squamous Cell Cancer (RICE) (NCT05621707)Shanghai Chest Hospital2022-11-02
First-line Treatment With Dacomitinib Plus Anlotinib for Patients With Advanced NSCLC With EGFR 21L858R Mutations (NCT05271916)Shanghai Chest Hospital2022-10-13
Electroacupuncture Intervention in Catheter Ablation of Atrial Fibrillation (NCT05575544)Shanghai Chest Hospital2022-10-11
Induction Chemoimmunotherapy in Combination With Chemoradiotherapy and Consolidation Immunotherapy in Unresectable Locally Advanced Non-Small Cell Lung Cancer (NCT07632365)Shanghai Chest Hospital2022-10-09
Feasibility of Thin Cp-EBUS Scope BF-UC290F for the Diagnosis of PPLs (NCT05512533)Shanghai Chest Hospital2022-09-02
Comparison of Peri-procedural Complications of Intracardiac Echocardiography and Transesophageal Echocardiography in Patients With Atrial Fibrillation (NCT05466266)Shanghai Chest Hospital2022-08-01
Exosomes Detection for the Prediction of the Efficacy and Adverse Reactions of Anlotinib in Patients With Advanced NSCLC (NCT05218759)Shanghai Chest Hospital2022-02-21
Augmented Reality-assisted Localization of Solitary Pulmonary Nodules for Precise Sublobar Lung Resection (NCT05162235)Shanghai Chest Hospital2022-01-01
China Lung Cancer Screening (CLUS) Study Version 3.0 (NCT05494021)Shanghai Chest Hospital2022-01-01
Recurrent Persistent Atrial Fibrillation:In-situ Ablation Vs Extensive Ablation (NCT06829446)Shanghai Chest Hospital2022-01-01
SHR-1701 for Consolidation Therapy After Concurrent Chemoradiotherapy in Inoperable Stage III NSCLC (NCT05177497)Shanghai Chest Hospital2022-01-01
Sintilimab Combined With Anlotinib for Perioperative Non-small Cell Lung Cancer Based on MRD Evaluation (NCT05460195)Shanghai Chest Hospital2022-01-01
Evaluate the Diagnostic Value of BTPNA for PPL: a Real-world Study (NCT04597346)Shanghai Chest Hospital2021-12-23
Catgut Embedding in Acupoints on Treating Persistent Atrial Fibrillation After Catheter Ablation (NCT05125042)Shanghai Chest Hospital2021-12-01
Catheter Ablation and Surgical Ablation of Persistent Atrial Fibrillation With Severe Atrial Fibrosis (NCT05153486)Shanghai Chest Hospital2021-12-01
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