| Bispecific CD19/CD20-Targeted Chimeric Antigen Receptor (CAR) Modified T Cells With 4-1BB and Mutated CD28 Costimulatory Domains in Patients With Relapsed or Refractory CD19+ Hematologic Malignancies (NCT07701889) | Roswell Park Cancer Institute | 2026-10-01 |
| Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer (NCT07745023) | Roswell Park Cancer Institute | 2026-09-30 |
| Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance (NCT07439471) | Roswell Park Cancer Institute | 2026-09-28 |
| Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream (NCT06334016) | Roswell Park Cancer Institute | 2026-09-15 |
| Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids (NCT06827054) | Roswell Park Cancer Institute | 2026-09-15 |
| Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors (NCT06565260) | Roswell Park Cancer Institute | 2026-09-01 |
| CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer (NCT07543172) | Roswell Park Cancer Institute | 2026-09-01 |
| Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms (NCT07679334) | Roswell Park Cancer Institute | 2026-09-01 |
| Comparing Two Weight Loss Programs for the Prevention of Kidney Cancer Progression Among Patients With Small Renal Masses on Active Surveillance (NCT07714018) | Roswell Park Cancer Institute | 2026-09-01 |
| Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer (NCT07718672) | Roswell Park Cancer Institute | 2026-09-01 |
| Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer (NCT06943664) | Roswell Park Cancer Institute | 2026-08-15 |
| Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers (NCT07553819) | Roswell Park Cancer Institute | 2026-08-01 |
| Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma (NCT06968195) | Roswell Park Cancer Institute | 2026-07-15 |
| A Food Security Intervention for the Prevention of Cancer in Low-income Families (NCT07039630) | Roswell Park Cancer Institute | 2026-07-15 |
| Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas (NCT06202066) | Roswell Park Cancer Institute | 2026-07-15 |
| Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy (NCT07075705) | Roswell Park Cancer Institute | 2026-07-15 |
| GB-5267 for the Treatment Platinum-Resistant Ovarian, Peritoneal, or Fallopian Tube Cancer (NCT07489287) | Roswell Park Cancer Institute | 2026-07-15 |
| Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue Sarcoma (NCT06670976) | Roswell Park Cancer Institute | 2026-05-15 |
| Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects (NCT07107139) | Roswell Park Cancer Institute | 2026-05-11 |
| New York Better Breathing Study (NCT06869447) | Roswell Park Cancer Institute | 2026-04-20 |
| GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer (NCT07017829) | Roswell Park Cancer Institute | 2026-04-01 |
| Selvigaltin With Standard of Care Treatment for the Treatment of Relapsed/Refractory Multiple Myeloma (NCT07082270) | Roswell Park Cancer Institute | 2026-04-01 |
| Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study (NCT07402577) | Roswell Park Cancer Institute | 2026-03-30 |
| Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer (NCT06434064) | Roswell Park Cancer Institute | 2026-03-03 |
| NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal Adenocarcinoma, Nectar Trial (NCT06821997) | Roswell Park Cancer Institute | 2026-03-02 |
| Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma (NCT07214298) | Roswell Park Cancer Institute | 2026-02-16 |
| Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers (NCT06977503) | Roswell Park Cancer Institute | 2026-02-04 |
| Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia (NCT06871410) | Roswell Park Cancer Institute | 2026-02-02 |
| A Cruciferous Vegetable Eating Program for the Reduction of Cancer Recurrence and Progression in Patients With Non-muscle Invasive Bladder Cancer (NCT06733363) | Roswell Park Cancer Institute | 2026-01-13 |
| Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO Trial (NCT06995508) | Roswell Park Cancer Institute | 2025-12-24 |
| Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas (NCT07182240) | Roswell Park Cancer Institute | 2025-12-22 |
| Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults (NCT06816459) | Roswell Park Cancer Institute | 2025-10-14 |
| FL118 for Treating Patients With Advanced Pancreatic Ductal Adenocarcinoma (NCT06206876) | Roswell Park Cancer Institute | 2025-10-01 |
| Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand (NCT07102082) | Roswell Park Cancer Institute | 2025-09-25 |
| A Financial Intervention (Financial Compass) to Identify and Address Financial Hardship Among Head and Neck Cancer Patients, Financial Compass Trial (NCT06896695) | Roswell Park Cancer Institute | 2025-09-23 |
| An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study (NCT06855706) | Roswell Park Cancer Institute | 2025-06-04 |
| Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma in Patients With Extramedullary Disease (NCT06627751) | Roswell Park Cancer Institute | 2025-05-01 |
| A Post-treatment Supportive Service Program for the Transition Into Survivorship for Black Women Breast Cancer Survivors in Western New York (NCT06833255) | Roswell Park Cancer Institute | 2025-04-21 |
| SX-682 in Combination With Carfilzomib, Daratumumab-Hyaluronidase, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma (NCT06622005) | Roswell Park Cancer Institute | 2025-04-10 |
| Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study) (NCT07167225) | Roswell Park Cancer Institute | 2025-04-03 |
| Virtual Reality for Symptom Management in Patients Undergoing Hematopoietic Stem Cell Transplantation (NCT06798701) | Roswell Park Cancer Institute | 2025-03-14 |
| MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence (NCT06323044) | Roswell Park Cancer Institute | 2025-02-11 |
| Dendritic Cell-Based Treatment Plus Immunotherapy for the Treatment of Metastatic or Unresectable Triple Negative Breast Cancer (NCT05539365) | Roswell Park Cancer Institute | 2025-02-01 |
| Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer (NCT06305598) | Roswell Park Cancer Institute | 2024-12-19 |
| A Patient Navigation Program for Addressing Disparities in Breast Cancer Care (NCT06350500) | Roswell Park Cancer Institute | 2024-12-15 |
| Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies (NCT06343376) | Roswell Park Cancer Institute | 2024-11-26 |
| A Community Health Education Intervention for Increasing Community-driven Actions to Reduce the Cancer Burden in Western New York (NCT06681077) | Roswell Park Cancer Institute | 2024-11-16 |
| Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma (NCT04093323) | Roswell Park Cancer Institute | 2024-11-13 |
| Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence: Study 3 (NCT06074666) | Roswell Park Cancer Institute | 2024-11-07 |
| Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction (NCT06306638) | Roswell Park Cancer Institute | 2024-10-01 |
| Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC) (NCT05518032) | Roswell Park Cancer Institute | 2024-10-01 |
| An Investigational Scan (124I-hJAA-F11 PET/CT) for Diagnosing Lung Cancer (NCT06427369) | Roswell Park Cancer Institute | 2024-10-01 |
| Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial (NCT06563388) | Roswell Park Cancer Institute | 2024-09-18 |
| Evaluating the Episodic Future Thinking Intervention for Reducing Cigarette Consumption in Cigarette Smokers (NCT05825001) | Roswell Park Cancer Institute | 2024-09-15 |
| Community-Based Physical Activity Intervention for Underserved Cancer Survivors (NCT06206863) | Roswell Park Cancer Institute | 2024-08-20 |
| Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant (NCT04876248) | Roswell Park Cancer Institute | 2024-08-19 |
| Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer (NCT06307548) | Roswell Park Cancer Institute | 2024-07-30 |
| Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer (NCT05231122) | Roswell Park Cancer Institute | 2024-03-12 |
| Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer (NCT05756166) | Roswell Park Cancer Institute | 2024-02-16 |
| Binimetinib and Palbociclib Before Surgery for the Treatment of Operable KRAS-Positive Lung, Colorectal, or Pancreatic Cancer (NCT04870034) | Roswell Park Cancer Institute | 2024-01-15 |
| An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers (NCT06414317) | Roswell Park Cancer Institute | 2024-01-12 |
| AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic Ductal Adenocarcinoma (NCT06320717) | Roswell Park Cancer Institute | 2024-01-02 |
| Quality of Life Intervention to Inform Patient Decision-Making in Early-Stage Lung Cancer (NCT05292521) | Roswell Park Cancer Institute | 2023-12-21 |
| EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer (NCT06011772) | Roswell Park Cancer Institute | 2023-12-18 |
| Specialized Immune Cells (nCTLs) and a Vaccine (Alpha-type-1 Polarized Dendritic Cells) in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (NCT03735589) | Roswell Park Cancer Institute | 2023-12-15 |
| Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Cancer (NCT05787834) | Roswell Park Cancer Institute | 2023-10-16 |
| Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography (NCT05876091) | Roswell Park Cancer Institute | 2023-08-30 |
| Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients (NCT05893940) | Roswell Park Cancer Institute | 2023-08-14 |
| Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy (NCT04646434) | Roswell Park Cancer Institute | 2023-07-13 |
| Implementation of Evidence-Based Strategy (PC TEACH) for the Optimization of HPV Vaccination in Rural Primary Care (NCT06256718) | Roswell Park Cancer Institute | 2023-05-24 |
| ivWatch in Prevention of Extravasation of Vesicants in an Oncology Setting (NCT06758011) | Roswell Park Cancer Institute | 2023-05-17 |
| Financial Health Educational Program for Increasing Financial Literacy Among Underserved Communities in Western New York (NCT05997589) | Roswell Park Cancer Institute | 2023-05-17 |
| APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion (NCT04919629) | Roswell Park Cancer Institute | 2023-04-27 |
| A Virtual Intervention to Improve Medication Adherence in Pediatric Cancer: MedSupport (NCT05150028) | Roswell Park Cancer Institute | 2023-04-11 |
| Consumer Assessment of Tobacco Flavor and Odor (NCT04358315) | Roswell Park Cancer Institute | 2023-04-03 |
| Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma (NCT05651594) | Roswell Park Cancer Institute | 2023-03-07 |
| A Cytomegalovirus-Directed Vaccine (CMV-alphaDC1) for Preventing Cytomegalovirus Infection or Reactivation in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (NCT05589844) | Roswell Park Cancer Institute | 2023-03-01 |
| Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer (NCT04348747) | Roswell Park Cancer Institute | 2022-12-19 |
| Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial (NCT05338905) | Roswell Park Cancer Institute | 2022-10-11 |
| Behavioral Parenting Skills As A Novel Target for Improving Pediatric Medication Adherence (NCT05587582) | Roswell Park Cancer Institute | 2022-09-01 |
| A Sugar-Sweetened Beverage Reduction Intervention for Native American Men (NCT06029517) | Roswell Park Cancer Institute | 2022-07-20 |
| Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer (NCT06456411) | Roswell Park Cancer Institute | 2022-07-12 |
| Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma (NCT05312255) | Roswell Park Cancer Institute | 2022-06-28 |
| Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems (NCT05423340) | Roswell Park Cancer Institute | 2022-06-12 |
| Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease (NCT04836429) | Roswell Park Cancer Institute | 2022-03-10 |
| Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer (NCT04119830) | Roswell Park Cancer Institute | 2022-02-01 |
| Decitabine/Cedazuridine and Enzalutamide for the Treatment of Metastatic Castrate Resistant Prostate Cancer (NCT05037500) | Roswell Park Cancer Institute | 2022-01-26 |
| Mindfulness Meditation (NCT05098002) | Roswell Park Cancer Institute | 2022-01-02 |
| A Pilot Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) in Central Non-Small Cell Lung Cancer (NCT05138900) | Roswell Park Cancer Institute | 2021-12-16 |
| Sleep and Circadian Rhythm Study in Head and Neck Cancer Patients (NCT05099952) | Roswell Park Cancer Institute | 2021-12-15 |
| A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence (NCT04298606) | Roswell Park Cancer Institute | 2021-11-22 |
| Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study] (NCT05030194) | Roswell Park Cancer Institute | 2021-10-21 |
| Weight Loss Interventions for Black Adults of Faith (NCT04557540) | Roswell Park Cancer Institute | 2021-09-25 |
| Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery (NCT03678350) | Roswell Park Cancer Institute | 2021-09-17 |
| CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old (NCT04269213) | Roswell Park Cancer Institute | 2021-07-29 |
| Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage Small Cell Lung Cancer (NCT04696575) | Roswell Park Cancer Institute | 2021-07-02 |
| Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer (NCT04511039) | Roswell Park Cancer Institute | 2021-06-08 |
| Thermal Therapy for the Treatment of Depression in Cancer Survivors, the S-WARM Study (NCT04803630) | Roswell Park Cancer Institute | 2021-05-06 |
| Behavioral Dietary Intervention for the Improvement of Bladder Cancer Survivorship (NCT04548193) | Roswell Park Cancer Institute | 2021-04-05 |
| Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma (NCT04682158) | Roswell Park Cancer Institute | 2021-04-01 |