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Neurocrine Biosciences

86 clinical trials · Sponsor

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RecordFirmDate
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years Old (NCT07536269)Neurocrine Biosciences2026-04-01
Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia (NCT07288333)Neurocrine Biosciences2026-02-16
Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia (NCT07365462)Neurocrine Biosciences2026-02-06
An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania (NCT07288320)Neurocrine Biosciences2025-12-24
Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia (NCT07227818)Neurocrine Biosciences2025-12-16
Pharmacokinetics, Safety and Tolerability of Crinecerfont in Participants With Congenital Adrenal Hyperplasia Who Are Less Than 2 Years Old (NCT07187375)Neurocrine Biosciences2025-09-30
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor (NCT07105111)Neurocrine Biosciences2025-08-29
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) (NCT07196501)Neurocrine Biosciences2025-08-18
NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia (NCT07105098)Neurocrine Biosciences2025-08-11
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia (NCT07114874)Neurocrine Biosciences2025-07-11
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) (NCT06963021)Neurocrine Biosciences2025-05-30
NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia (NCT06963034)Neurocrine Biosciences2025-05-08
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) (NCT06966401)Neurocrine Biosciences2025-04-16
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) (NCT06911112)Neurocrine Biosciences2025-03-31
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) (NCT06786624)Neurocrine Biosciences2025-01-22
Long-term Study to Evaluate Safety and Tolerability of Valbenazine in Participants With Chorea Associated With Huntington Disease in Canada (NCT06312189)Neurocrine Biosciences2024-04-24
A Study to Evaluate the Efficacy and Safety of NBI-1070770 in Adults With Major Depressive Disorder (NCT06267846)Neurocrine Biosciences2024-03-20
Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia (NCT05859698)Neurocrine Biosciences2023-05-09
Study to Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as an Adjunctive Treatment for Schizophrenia (NCT05654870)Neurocrine Biosciences2023-01-05
Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures (NCT05493293)Neurocrine Biosciences2022-11-09
Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-1117568 in Adults With Schizophrenia (NCT05545111)Neurocrine Biosciences2022-10-04
Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE (NCT05226780)Neurocrine Biosciences2022-07-12
Extension Study to Evaluate NBI-827104 in Pediatric Participants With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep (NCT05301894)Neurocrine Biosciences2022-06-07
Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral Palsy (NCT05206513)Neurocrine Biosciences2022-04-15
Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD) (NCT05203341)Neurocrine Biosciences2022-02-21
Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE) (NCT04873869)Neurocrine Biosciences2022-01-31
Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia (NCT05182476)Neurocrine Biosciences2021-12-07
Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD (NCT05165394)Neurocrine Biosciences2021-11-30
Journey Study: Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as Adjunctive Treatment for Schizophrenia (NCT05110157)Neurocrine Biosciences2021-11-29
A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures (NCT05159908)Neurocrine Biosciences2021-11-08
Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Participants With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study) (NCT04806451)Neurocrine Biosciences2021-06-25
Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep (NCT04625101)Neurocrine Biosciences2021-04-26
Safety, Efficacy, and Tolerability of NBI-827104 for the Treatment of Essential Tremor (NCT04880616)Neurocrine Biosciences2021-04-20
Open-Label Rollover Study for Continuing Valbenazine Administration for the Treatment of Chorea Associated With Huntington Disease (NCT04400331)Neurocrine Biosciences2020-09-18
A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants (NCT04234672)Neurocrine Biosciences2020-02-17
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 (Crinecerfont) in Pediatric Participants With Congenital Adrenal Hyperplasia (NCT04045145)Neurocrine Biosciences2019-12-12
Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington Disease (NCT04102579)Neurocrine Biosciences2019-11-13
Persistence of Effect and Safety of Valbenazine for the Treatment of Tardive Dyskinesia (NCT03891862)Neurocrine Biosciences2019-03-18
A Study to Evaluate Central Nervous System (CNS) Pharmacodynamic Activity of TAK-653 in Healthy Participants Using Transcranial Magnetic Stimulation (TMS) (NCT03792672)Neurocrine Biosciences2019-02-11
A Study to Evaluate the Relative Bioavailability (BA) and Effect of Food on TAK-831 Tablet Formulations in Healthy Participants (NCT03706469)Neurocrine Biosciences2018-10-18
Rollover Study for Continuing NBI-98854 Administration in Pediatric Subjects With Tourette Syndrome (NCT03732534)Neurocrine Biosciences2018-10-17
VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1) (NCT03562494)Neurocrine Biosciences2018-10-17
Phase 1 Study of TAK-831 in Healthy Adult Asian Subjects (NCT03687684)Neurocrine Biosciences2018-10-09
The Potential for Clinical Dependence and Withdrawal Symptoms Associated With Valbenazine (NCT03698331)Neurocrine Biosciences2018-09-14
Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome (NCT03530293)Neurocrine Biosciences2018-04-17
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 in Adults With Congenital Adrenal Hyperplasia (NCT03525886)Neurocrine Biosciences2018-04-10
Open-Label Safety and Tolerability Study of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome (NCT03444038)Neurocrine Biosciences2018-02-08
A Study to Evaluate Multiple Oral Doses of Luvadaxistat in Adults With Schizophrenia (NCT03359785)Neurocrine Biosciences2018-01-10
A Randomized, Double-Blind, Placebo Controlled, Two-Period Cross-Over, Proof of Activity Study to Evaluate the Effects of TAK-041 on Motivational Anhedonia as Add-On to Antipsychotics in Participants With Stable Schizophrenia (NCT03319953)Neurocrine Biosciences2017-12-21
Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia (NCT03214588)Neurocrine Biosciences2017-11-08
Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome (NCT03325010)Neurocrine Biosciences2017-10-05

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