| Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive Psychotherapy (NCT07640802) | National Institute of Mental Health (NIMH) | 2026-08-26 |
| Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) (NCT07566468) | National Institute of Mental Health (NIMH) | 2026-08-26 |
| PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) (NCT07169630) | National Institute of Mental Health (NIMH) | 2026-08-26 |
| Augmenting Parent Management Training for Child Temper Outbursts Using a Digital Tool (NCT07764536) | National Institute of Mental Health (NIMH) | 2026-08-26 |
| PET Imaging of Noradrenergic Transmission in the Brain (NCT07686393) | National Institute of Mental Health (NIMH) | 2026-08-14 |
| Evaluation of [11C]ZTP-1 to Image PDE4B (NCT07625345) | National Institute of Mental Health (NIMH) | 2026-07-01 |
| Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder (NCT05652465) | National Institute of Mental Health (NIMH) | 2026-04-25 |
| Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) (NCT07027839) | National Institute of Mental Health (NIMH) | 2025-12-11 |
| PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) (NCT06920628) | National Institute of Mental Health (NIMH) | 2025-06-18 |
| Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers (NCT06874205) | National Institute of Mental Health (NIMH) | 2025-04-11 |
| PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder (NCT06795581) | National Institute of Mental Health (NIMH) | 2025-03-20 |
| Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST) (NCT03895658) | National Institute of Mental Health (NIMH) | 2025-02-26 |
| Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers (NCT06484088) | National Institute of Mental Health (NIMH) | 2025-02-21 |
| Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety (NCT06595953) | National Institute of Mental Health (NIMH) | 2024-12-04 |
| Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression (NCT06511908) | National Institute of Mental Health (NIMH) | 2024-11-06 |
| Natural History of Depression, Bipolar Disorder and Suicide Risk (NCT06462196) | National Institute of Mental Health (NIMH) | 2024-09-09 |
| Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial (NCT05608434) | National Institute of Mental Health (NIMH) | 2024-03-15 |
| NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder (NCT05669703) | National Institute of Mental Health (NIMH) | 2023-11-03 |
| State-dependent Interoception, Value-based Decision-making, and Introspection (NCT05666726) | National Institute of Mental Health (NIMH) | 2023-07-25 |
| [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET (NCT05703685) | National Institute of Mental Health (NIMH) | 2023-06-22 |
| [11C]-(R)-Rolipram to Measure cAMP Signaling Before and After Ketamine (NCT05522673) | National Institute of Mental Health (NIMH) | 2023-02-08 |
| [18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy Subjects (NCT05564429) | National Institute of Mental Health (NIMH) | 2023-02-02 |
| Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD) (NCT05357495) | National Institute of Mental Health (NIMH) | 2023-01-05 |
| Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD) (NCT05172271) | National Institute of Mental Health (NIMH) | 2022-11-08 |
| Developing Brain, Impulsivity and Compulsivity (NCT04631042) | National Institute of Mental Health (NIMH) | 2022-09-30 |
| PET Imaging of Cyclooxygenase in Multiple Sclerosis (NCT05062083) | National Institute of Mental Health (NIMH) | 2022-06-07 |
| Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array (NCT04950309) | National Institute of Mental Health (NIMH) | 2022-05-12 |
| Identifying Decision Making Parameters in Healthy Volunteers and Anxiety Patients (NCT05092971) | National Institute of Mental Health (NIMH) | 2022-03-03 |
| Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations (NCT04639830) | National Institute of Mental Health (NIMH) | 2021-11-09 |
| Long-term Observation of Participants With Mood Disorders (NCT04877977) | National Institute of Mental Health (NIMH) | 2021-08-17 |
| PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease (NCT04396873) | National Institute of Mental Health (NIMH) | 2021-08-17 |
| PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD) (NCT04582916) | National Institute of Mental Health (NIMH) | 2021-07-20 |
| Ask Suicide-Screening Questions (ASQ) for Youth With Autism Spectrum and Neurodevelopmental Disorders (NCT04317118) | National Institute of Mental Health (NIMH) | 2021-07-15 |
| Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder (NCT04798274) | National Institute of Mental Health (NIMH) | 2021-06-15 |
| Antidepressant Effects of TS-161 in Treatment-Resistant Depression (NCT04821271) | National Institute of Mental Health (NIMH) | 2021-06-10 |
| Emotional, Social, Cognitive and Behavioral Sequalae of the COVID-19 Pandemic (NCT04823988) | National Institute of Mental Health (NIMH) | 2021-04-13 |
| Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine (NCT04711005) | National Institute of Mental Health (NIMH) | 2021-01-11 |
| Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen (NCT04684615) | National Institute of Mental Health (NIMH) | 2020-12-28 |
| Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses (NCT04377100) | National Institute of Mental Health (NIMH) | 2020-05-08 |
| Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers (NCT04339790) | National Institute of Mental Health (NIMH) | 2020-04-07 |
| Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression (NCT03973268) | National Institute of Mental Health (NIMH) | 2020-01-21 |
| PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand (NCT03958630) | National Institute of Mental Health (NIMH) | 2019-07-03 |
| Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions (NCT03912428) | National Institute of Mental Health (NIMH) | 2019-06-14 |
| Estrogen Receptor Beta and Mood (NCT03689543) | National Institute of Mental Health (NIMH) | 2019-05-23 |
| Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D) (NCT03861000) | National Institute of Mental Health (NIMH) | 2019-03-12 |
| Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes (NCT03289923) | National Institute of Mental Health (NIMH) | 2018-05-17 |
| PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome (NCT02743377) | National Institute of Mental Health (NIMH) | 2018-04-04 |
| Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) (NCT03507218) | National Institute of Mental Health (NIMH) | 2018-03-20 |
| Development of Non-Invasive Brain Stimulation Techniques (NCT03351764) | National Institute of Mental Health (NIMH) | 2018-01-11 |
| Characterization and Treatment of Adolescent Depression (NCT03388606) | National Institute of Mental Health (NIMH) | 2017-12-28 |
| Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies (NCT03304665) | National Institute of Mental Health (NIMH) | 2017-11-01 |
| Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1) (NCT03324646) | National Institute of Mental Health (NIMH) | 2017-10-03 |
| Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder (NCT03065335) | National Institute of Mental Health (NIMH) | 2017-05-25 |
| Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core (NCT03092687) | National Institute of Mental Health (NIMH) | 2017-03-21 |
| Effect of Transcranial Magnetic Stimulation to the Frontoparietal Attention Network on Anxiety Potentiated Startle (NCT03027414) | National Institute of Mental Health (NIMH) | 2017-01-23 |
| Novel Positron Emission Tomography (PET) Radiotracer to Image Phosphodiesterase-4B (PDE4B) (NCT03030391) | National Institute of Mental Health (NIMH) | 2017-01-10 |
| Use of the Ask Suicide-Screening Questions (ASQ) in Pediatric Outpatient Settings (NCT02830334) | National Institute of Mental Health (NIMH) | 2016-07-09 |
| Main Study: Influence on Plasticity of Brain Temperature Sub-Study: Phase Triggered Paired Associative Stimulation (PAS) (NCT02363296) | National Institute of Mental Health (NIMH) | 2016-05-03 |
| Evaluation of a Novel PET Radioligand to Image OGA (NCT03632226) | National Institute of Mental Health (NIMH) | 2016-05-02 |
| Neurobiology of Suicide (NCT02543983) | National Institute of Mental Health (NIMH) | 2015-12-01 |
| Psychological Treatments for Youth With Severe Irritability. (NCT02531893) | National Institute of Mental Health (NIMH) | 2015-11-17 |
| Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder (NCT02484456) | National Institute of Mental Health (NIMH) | 2015-10-14 |
| Spatial Context and Fear Learning (NCT02423044) | National Institute of Mental Health (NIMH) | 2015-04-18 |
| Checking Out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress (NCT02423031) | National Institute of Mental Health (NIMH) | 2015-04-14 |
| Investigating the Impact of Methylphenidate on Neural Response in Disruptive Behavioral Disorder (NCT02247986) | National Institute of Mental Health (NIMH) | 2014-09-04 |
| PET Imaging in Chronic Traumatic Encephalopathy (NCT02211820) | National Institute of Mental Health (NIMH) | 2014-08-01 |
| Specific PET Radioligand Binding to Translocator Protein (NCT02181582) | National Institute of Mental Health (NIMH) | 2014-06-24 |
| Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety (NCT02153944) | National Institute of Mental Health (NIMH) | 2014-06-16 |
| Ask Suicide-Screening Questions to Everyone in Medical Settings (asQ em): Development of a Suicide Risk Screening Instrument for Adult Medical Inpatients (NCT02140177) | National Institute of Mental Health (NIMH) | 2014-05-14 |
| Assessment of [11C]ER176 to Image Translocator Protein in Brain and Whole Body of Healthy People (NCT02147392) | National Institute of Mental Health (NIMH) | 2014-05-14 |
| Evaluation of a Novel Positron Emission Tomography (PET Radiotracer for TARP Gamma-8 (NCT02108015) | National Institute of Mental Health (NIMH) | 2014-03-05 |
| Imaging and Genetic Investigation of Learning and Decision Making (NCT01950377) | National Institute of Mental Health (NIMH) | 2014-02-11 |
| Validation of the Ask Suicide-Screening Questions (ASQ) in the Inpatient Medical Setting (NCT02050867) | National Institute of Mental Health (NIMH) | 2014-01-29 |
| Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression? (NCT02049385) | National Institute of Mental Health (NIMH) | 2014-01-03 |
| PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX (NCT02230592) | National Institute of Mental Health (NIMH) | 2013-11-08 |
| Evaluation of Two Radioactive Chemicals to Image mGluR5 Receptors in Brain (NCT01896843) | National Institute of Mental Health (NIMH) | 2013-06-27 |
| A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism (NCT01887132) | National Institute of Mental Health (NIMH) | 2013-06-01 |
| Brain Inflammation in Major Depressive Disorder Background (NCT01851356) | National Institute of Mental Health (NIMH) | 2013-05-08 |
| Effects of Atypical Antipsychotics on Brain Function in Children and Teens With Conduct Disorders (NCT01867398) | National Institute of Mental Health (NIMH) | 2013-04-29 |
| Brain Stimulation and Vision Testing (NCT01617408) | National Institute of Mental Health (NIMH) | 2013-03-04 |
| Study of [11C]DPA-713 for Temporal Lobe Epilepsy (NCT01793532) | National Institute of Mental Health (NIMH) | 2013-01-31 |
| A Pilot Study to Extend the K-SADS-PL to Adolescents and Young Adults (NCT01778478) | National Institute of Mental Health (NIMH) | 2013-01-26 |
| Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders (NCT01778504) | National Institute of Mental Health (NIMH) | 2012-12-27 |
| Near Infrared Spectroscopy in Children With Autism and ADHD (NCT01730079) | National Institute of Mental Health (NIMH) | 2012-10-23 |
| Daily Intranasal Oxytocin for Childhood-Onset Schizophrenia (NCT01712646) | National Institute of Mental Health (NIMH) | 2012-10-05 |
| Depression Outcomes Study of Exercise (NCT00964054) | National Institute of Mental Health (NIMH) | 2012-09-01 |
| Top-Down Attentional Control of Visual-Processing (NCT01087281) | National Institute of Mental Health (NIMH) | 2012-07-23 |
| Brain Imaging, Genetics and Treatment for Major Depression (NCT01568684) | National Institute of Mental Health (NIMH) | 2012-03-12 |
| Translocator Protein and Inflammation After Traumatic Brain Injury (NCT01547780) | National Institute of Mental Health (NIMH) | 2012-01-20 |
| Mild Neurocognitive Disorder in HIV Infection of the Brain (NCT01547754) | National Institute of Mental Health (NIMH) | 2012-01-09 |
| Assessing Suicide Risk in Adolescents With Developmental Delays (NCT01517126) | National Institute of Mental Health (NIMH) | 2012-01-06 |
| A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty (NCT01434368) | National Institute of Mental Health (NIMH) | 2011-11-23 |
| Imaging of Brain Receptors Using (11C)mGlu1 (NCT01420952) | National Institute of Mental Health (NIMH) | 2011-07-29 |
| Imaging of CB1 Receptors Using (11C)SD5024 (NCT01399398) | National Institute of Mental Health (NIMH) | 2011-06-22 |
| (18F)FCWAY and the Blood-Brain Barrier (NCT01386476) | National Institute of Mental Health (NIMH) | 2011-06-15 |
| Study of Toddlers With Language Delay (NCT01339767) | National Institute of Mental Health (NIMH) | 2011-04-18 |
| Oxytocin and Arginine Vasopressin in Pain Relief (NCT01328561) | National Institute of Mental Health (NIMH) | 2011-03-17 |
| A Study of the Association Between Autism and Immune Changes in the Brain (NCT01322555) | National Institute of Mental Health (NIMH) | 2011-03-04 |
| Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive Disorder (NCT01313403) | National Institute of Mental Health (NIMH) | 2011-02-10 |
| Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle (NCT01266577) | National Institute of Mental Health (NIMH) | 2011-01-27 |