Atlas Trials

Epizyme, Inc.

21 clinical trials · Sponsor

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RecordFirmDate
A Study to Assess Efficacy and Safety of Oral Tazemetostat in Adult Participants With Relapsed/Refractory Follicular Lymphoma That Does Not Have an "EZH2 Gain-of-function" Genetic Mutation (NCT06068881)Epizyme, Inc.2025-09-02
A Study of the Safety, Tolerability and Effectiveness of EZM0414 (IPN60210) Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma (NCT05121103)Epizyme, Inc.2022-05-31
A Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer. (NCT05205252)Epizyme, Inc.2021-12-22
SYMPHONY-2, A Trial to Examine Combination of Tazemetostat With Rituximab in Subjects With Relapsed/Refractory Follicular Lymphoma (NCT04762160)Epizyme, Inc.2020-12-15
A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma. (NCT04224493)Epizyme, Inc.2020-06-11
Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels (NCT04537715)Epizyme, Inc.2020-04-23
A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function (NCT04241835)Epizyme, Inc.2020-01-15
Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma (NCT04204941)Epizyme, Inc.2019-12-19
A Study of Tazemetostat With Enzalutamide or Abiraterone/Prednisone in Participants With Advanced Prostate Cancer (NCT04179864)Epizyme, Inc.2019-11-18
Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors (NCT03010982)Epizyme, Inc.2018-06-20
Epithelioid Sarcoma Natural History Study (NCT03837678)Epizyme, Inc.2018-06-04

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