| Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial (NCT07650656) | City of Hope Medical Center | 2027-05-15 |
| Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma (NCT07758673) | City of Hope Medical Center | 2027-04-17 |
| Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome (NCT07582172) | City of Hope Medical Center | 2027-04-05 |
| Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease (NCT07733141) | City of Hope Medical Center | 2027-03-01 |
| A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer (NCT07741968) | City of Hope Medical Center | 2027-02-22 |
| The High Fiber Program to Increase Fiber Intake Among Patients Undergoing Allogeneic Hematopoietic Cell Transplant (NCT07664670) | City of Hope Medical Center | 2027-02-13 |
| Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root Involvement (NCT07707024) | City of Hope Medical Center | 2027-01-10 |
| Belinostat in Combination With Azacitidine or Pralatrexate for the Treatment of Relapse or Refractory T-cell Lymphoma (NCT07691450) | City of Hope Medical Center | 2027-01-03 |
| Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules (NCT03676647) | City of Hope Medical Center | 2027-01-01 |
| Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery (NCT07037004) | City of Hope Medical Center | 2027-01-01 |
| Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Prostate Cancer (NCT07769372) | City of Hope Medical Center | 2027-01-01 |
| Environmental Exposure Assessment in High-Risk and Early-Onset Breast Cancer Care (NCT07690852) | City of Hope Medical Center | 2026-12-28 |
| Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3 (NCT07595874) | City of Hope Medical Center | 2026-12-27 |
| Circadian-Optimized Light Therapy for the Treatment of Patients With Advanced Melanoma Receiving Tumor-Infiltrating Lymphocyte Therapy (NCT07628894) | City of Hope Medical Center | 2026-12-23 |
| Golcadomide in Combination With Rituximab for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma (NCT07578077) | City of Hope Medical Center | 2026-12-21 |
| Biology Guided Therapy Recommendations for Treatment Determination of Hormone Receptor-Positive Advanced, Unresectable or Metastatic Breast Cancer, ENDORSE Trial (NCT07590583) | City of Hope Medical Center | 2026-12-19 |
| Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (NCT07582159) | City of Hope Medical Center | 2026-12-19 |
| Asciminib as Maintenance Treatment After Cellular Therapies for Adults With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (NCT07040982) | City of Hope Medical Center | 2026-12-19 |
| 64Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic Cancer (NCT07608627) | City of Hope Medical Center | 2026-12-16 |
| Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody Rituximab for the Treatment of Marginal Zone Lymphoma (NCT07583810) | City of Hope Medical Center | 2026-12-16 |
| BSB-2002 After Cyclophosphamide and Fludarabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With NPM1 Mutation (NCT07583303) | City of Hope Medical Center | 2026-12-14 |
| Tear Fluid for the Detection of Tumor-associated Extracellular Vesicles in Glioblastoma Patients (NCT07775534) | City of Hope Medical Center | 2026-12-09 |
| Wearable Data for Personalized Prognostication in Cancer: A Registry Protocol (NCT07691008) | City of Hope Medical Center | 2026-12-01 |
| Zanzalintinib and MO-03 for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy (NCT07578025) | City of Hope Medical Center | 2026-11-28 |
| Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients (NCT07608445) | City of Hope Medical Center | 2026-11-13 |
| Exercise and Mortality in Middle-Aged and Older Adults (NCT07224659) | City of Hope Medical Center | 2026-10-01 |
| Scheduled Meditation for Improving Postoperative Outcomes in Patients Undergoing Pancreatectomy (NCT07608458) | City of Hope Medical Center | 2026-10-01 |
| Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma (NCT06675123) | City of Hope Medical Center | 2026-10-01 |
| Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial (NCT07271355) | City of Hope Medical Center | 2026-10-01 |
| Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal Cell Cancer (NCT07226544) | City of Hope Medical Center | 2026-10-01 |
| Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard Treatment (NCT07275216) | City of Hope Medical Center | 2026-10-01 |
| Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas (NCT07293403) | City of Hope Medical Center | 2026-10-01 |
| Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation (NCT07235501) | City of Hope Medical Center | 2026-10-01 |
| Geriatric Assessment and Management for Older Adults Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer and Their Family Caregivers (NCT07225855) | City of Hope Medical Center | 2026-10-01 |
| Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers (NCT07611370) | City of Hope Medical Center | 2026-09-30 |
| A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab (NCT07619599) | City of Hope Medical Center | 2026-09-14 |
| A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery (NCT07612085) | City of Hope Medical Center | 2026-09-02 |
| Autologous CD6-CAR Treg Cells for Patients With Stage 3 Type 1 Diabetes (NCT07395050) | City of Hope Medical Center | 2026-09-01 |
| RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy (NCT07218692) | City of Hope Medical Center | 2026-08-11 |
| Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer (NCT07363408) | City of Hope Medical Center | 2026-07-21 |
| Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer (NCT07226102) | City of Hope Medical Center | 2026-07-16 |
| Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant (NCT06996119) | City of Hope Medical Center | 2026-06-12 |
| Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas (NCT07544992) | City of Hope Medical Center | 2026-05-26 |
| Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia (NCT07133997) | City of Hope Medical Center | 2026-05-20 |
| Circulating Tumor DNA Based Minimal Residual Disease Detection for Patients With Early-Stage Breast Cancer (NCT07136493) | City of Hope Medical Center | 2026-05-12 |
| A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant (NCT07020533) | City of Hope Medical Center | 2026-05-08 |
| Molecular Profiling for Risk Stratification in Appendiceal Cancer (NCT07587268) | City of Hope Medical Center | 2026-05-01 |
| Alternative Splicing Based Prediction of Chemotherapy Response in Gastric Cancer (NCT07587229) | City of Hope Medical Center | 2026-05-01 |
| Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation (NCT07025538) | City of Hope Medical Center | 2026-04-29 |
| L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance (NCT07220447) | City of Hope Medical Center | 2026-04-21 |
| Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma (NCT07365306) | City of Hope Medical Center | 2026-04-15 |
| Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial (NCT07288034) | City of Hope Medical Center | 2026-04-08 |
| Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer (NCT07128680) | City of Hope Medical Center | 2026-03-23 |
| A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes (NCT07061574) | City of Hope Medical Center | 2026-03-10 |
| 177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer (NCT07219147) | City of Hope Medical Center | 2026-03-06 |
| Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors (NCT07218913) | City of Hope Medical Center | 2026-02-19 |
| Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells (NCT07042438) | City of Hope Medical Center | 2026-02-11 |
| Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer (NCT06860815) | City of Hope Medical Center | 2026-01-30 |
| Individualized AML Treatment (NCT07613385) | City of Hope Medical Center | 2026-01-28 |
| A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients (NCT07225738) | City of Hope Medical Center | 2026-01-21 |
| Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy (NCT07186192) | City of Hope Medical Center | 2026-01-14 |
| Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial (NCT07218510) | City of Hope Medical Center | 2026-01-07 |
| Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia (NCT06735690) | City of Hope Medical Center | 2025-12-30 |
| Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas (NCT07278856) | City of Hope Medical Center | 2025-12-16 |
| Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy (NCT07218718) | City of Hope Medical Center | 2025-12-11 |
| STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma (NCT06626256) | City of Hope Medical Center | 2025-12-05 |
| Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R) (NCT07210086) | City of Hope Medical Center | 2025-11-26 |
| Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial (NCT07202247) | City of Hope Medical Center | 2025-11-05 |
| Nab-Paclitaxel PIPAC in Combination With Paclitaxel and Ramucirumab for the Treatment of Stomach Cancer With Peritoneal Metastases (NCT06675136) | City of Hope Medical Center | 2025-10-29 |
| MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia (NCT07025564) | City of Hope Medical Center | 2025-10-24 |
| Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma (NCT06918431) | City of Hope Medical Center | 2025-10-10 |
| Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors (NCT06731894) | City of Hope Medical Center | 2025-10-03 |
| Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients (NCT07125729) | City of Hope Medical Center | 2025-08-29 |
| External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease (NCT06572605) | City of Hope Medical Center | 2025-08-29 |
| Different Types of Massage Therapy to Reduce Anxiety During Chemotherapy Infusion in Patients With Cancer (NCT07184294) | City of Hope Medical Center | 2025-08-28 |
| Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer (NCT06954831) | City of Hope Medical Center | 2025-08-28 |
| Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NCT06859008) | City of Hope Medical Center | 2025-08-25 |
| Indocyanine Green Fluoroscopy and SPY Angiography for the Assessment of Lymphatic Structure in Breast Cancer Patients at Risk for Breast Cancer-Related Lymphedema (NCT06672224) | City of Hope Medical Center | 2025-08-14 |
| Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation (NCT06735664) | City of Hope Medical Center | 2025-08-14 |
| A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (NCT06763341) | City of Hope Medical Center | 2025-07-30 |
| Glofitamab With Obinutuzumab Pre-treatment for the Treatment of Central Nervous System Lymphoma (NCT06922604) | City of Hope Medical Center | 2025-07-30 |
| Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting (NCT07126301) | City of Hope Medical Center | 2025-07-08 |
| 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome (NCT06287944) | City of Hope Medical Center | 2025-07-01 |
| Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers (NCT06985784) | City of Hope Medical Center | 2025-06-25 |
| Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma (NCT06815029) | City of Hope Medical Center | 2025-06-17 |
| Multi-antigen Specific CD8+ T Cells With Decitabine and Lymphodepleting Chemotherapy for the Treatment of Patients With Relapsed or Refractory AML or MDS Following an Allogeneic Hematopoietic Cell Transplantation From a Matched Donor (NCT06572631) | City of Hope Medical Center | 2025-06-07 |
| Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer (NCT06130826) | City of Hope Medical Center | 2025-05-27 |
| Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia (NCT06454409) | City of Hope Medical Center | 2025-05-21 |
| FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery (NCT06780787) | City of Hope Medical Center | 2025-05-20 |
| Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer (NCT06910761) | City of Hope Medical Center | 2025-05-05 |
| Niraparib and Selenium for the Treatment of Recurrent BRCA Negative Platinum Resistant Ovarian Cancer (NCT05672095) | City of Hope Medical Center | 2025-04-18 |
| Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning (NCT06815003) | City of Hope Medical Center | 2025-04-18 |
| Cemiplimab for the Treatment of Untreated Brain Metastases From PD-L1 >= 50% Non-Small Cell Lung Cancer (NCT05840770) | City of Hope Medical Center | 2025-04-15 |
| Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial (NCT06834126) | City of Hope Medical Center | 2025-04-07 |
| [18F]-rhPSMA PET-CT Imaging Performance in Patients With Prostate Cancer (NCT06580015) | City of Hope Medical Center | 2025-03-25 |
| Epcoritamab and Tazemetostat for the Treatment of Relapsed or Refractory Grade I-IIIa Follicular Lymphoma (NCT06575686) | City of Hope Medical Center | 2025-03-11 |
| Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant (NCT06498973) | City of Hope Medical Center | 2025-01-28 |
| Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma (NCT06572618) | City of Hope Medical Center | 2025-01-22 |
| Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant (NCT06543381) | City of Hope Medical Center | 2025-01-17 |
| Project for Multi-Omics-Based Early Detection of Hepatocellular Carcinoma (PROMETHEA Study) (NCT07265271) | City of Hope Medical Center | 2025-01-15 |