| Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk Neuroblastoma (NCT06858501) | Children's Oncology Group | 2026-09-22 |
| A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia (NCT07498465) | Children's Oncology Group | 2026-09-10 |
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) (NCT07072585) | Children's Oncology Group | 2026-08-28 |
| A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information (NCT07621614) | Children's Oncology Group | 2026-08-18 |
| A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS) (NCT07466316) | Children's Oncology Group | 2026-07-14 |
| Quality of End-of-Life Care for Children With Cancer (NCT07412002) | Children's Oncology Group | 2026-06-15 |
| Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia (NCT07022678) | Children's Oncology Group | 2026-05-26 |
| Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body (NCT06820957) | Children's Oncology Group | 2025-11-10 |
| Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma (NCT06894979) | Children's Oncology Group | 2025-06-18 |
| Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma (NCT06620302) | Children's Oncology Group | 2025-06-12 |
| A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT) (NCT06401330) | Children's Oncology Group | 2025-04-15 |
| Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma (NCT06647953) | Children's Oncology Group | 2025-03-21 |
| Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer (NCT06513962) | Children's Oncology Group | 2025-02-27 |
| A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy (NCT06247787) | Children's Oncology Group | 2025-02-04 |
| A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at Home (NCT06639958) | Children's Oncology Group | 2024-12-04 |
| A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma (NCT06368817) | Children's Oncology Group | 2024-10-22 |
| A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study (NCT06410209) | Children's Oncology Group | 2024-10-15 |
| A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients (NCT05711667) | Children's Oncology Group | 2024-07-11 |
| Somatic Mosaicism in Twins Discordant for Childhood Cancer (NCT06054295) | Children's Oncology Group | 2024-06-03 |
| A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia (NCT05702645) | Children's Oncology Group | 2023-11-30 |
| A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma (NCT05705531) | Children's Oncology Group | 2023-08-18 |
| Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation (NCT04203316) | Children's Oncology Group | 2023-08-14 |
| Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma (NCT05602194) | Children's Oncology Group | 2023-08-14 |
| A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat (NCT05320380) | Children's Oncology Group | 2023-08-01 |
| Molecular Epidemiology of Pediatric Germ Cell Tumors (NCT05564026) | Children's Oncology Group | 2023-04-12 |
| Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome (NCT05457556) | Children's Oncology Group | 2023-03-15 |
| A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss (NCT05382338) | Children's Oncology Group | 2023-02-20 |
| Vincristine Pharmacokinetics in Infants (NCT05359237) | Children's Oncology Group | 2022-11-16 |
| A Study to Give Treatment Inside the Eye to Treat Retinoblastoma (NCT05504291) | Children's Oncology Group | 2022-11-04 |
| Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma (NCT05304585) | Children's Oncology Group | 2022-08-04 |
| HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma (NCT04903080) | Children's Oncology Group | 2022-07-27 |
| A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (NCT04978727) | Children's Oncology Group | 2022-07-01 |
| A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain Tumor (NCT04939597) | Children's Oncology Group | 2022-05-10 |
| Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer (NCT05228275) | Children's Oncology Group | 2022-04-08 |
| Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma (NCT05235165) | Children's Oncology Group | 2022-04-01 |
| Financial Distress During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States (NCT04928599) | Children's Oncology Group | 2022-03-14 |
| CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma (NCT04870944) | Children's Oncology Group | 2022-01-28 |
| Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors (NCT04851119) | Children's Oncology Group | 2021-11-08 |
| A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma (NCT04994132) | Children's Oncology Group | 2021-09-14 |
| Genetic Overlap Between Anomalies and Cancer in Kids in the Children's Oncology Group: The COG GOBACK Study (NCT05071859) | Children's Oncology Group | 2021-09-10 |
| Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE (NCT05020951) | Children's Oncology Group | 2021-08-28 |
| Backtracking Leukemia-Typical Somatic Mutations in Cord Blood (NCT05014165) | Children's Oncology Group | 2021-08-25 |
| A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT (NCT04684368) | Children's Oncology Group | 2021-07-13 |
| Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL) (NCT04385277) | Children's Oncology Group | 2020-12-31 |
| Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study (NCT04089358) | Children's Oncology Group | 2020-12-07 |
| A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT (NCT04322318) | Children's Oncology Group | 2020-10-19 |
| A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery (NCT04195399) | Children's Oncology Group | 2020-10-07 |
| A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations (NCT04293562) | Children's Oncology Group | 2020-07-21 |
| Inherited Genetic Susceptibility in Langerhans Cell Histiocytosis (LCH) (NCT04100408) | Children's Oncology Group | 2020-06-01 |
| Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid Leukemia (NCT04158739) | Children's Oncology Group | 2020-01-22 |
| Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia (NCT03817398) | Children's Oncology Group | 2019-11-08 |
| Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy (NCT03959085) | Children's Oncology Group | 2019-10-31 |
| Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia (NCT03834961) | Children's Oncology Group | 2019-10-25 |
| Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma (NCT03794349) | Children's Oncology Group | 2019-07-08 |
| Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL) (NCT03792256) | Children's Oncology Group | 2019-04-11 |
| Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery (NCT03533582) | Children's Oncology Group | 2018-05-24 |
| Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL) (NCT03126916) | Children's Oncology Group | 2018-05-14 |
| Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant (NCT03057054) | Children's Oncology Group | 2018-04-30 |
| Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors (NCT03320330) | Children's Oncology Group | 2018-01-31 |
| Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma (NCT03323034) | Children's Oncology Group | 2018-01-11 |
| Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia (NCT03204916) | Children's Oncology Group | 2017-12-18 |
| Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors (NCT03206450) | Children's Oncology Group | 2017-12-06 |
| Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer (NCT03223753) | Children's Oncology Group | 2017-11-29 |
| Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma (NCT02724579) | Children's Oncology Group | 2017-11-17 |
| Genetic Mutational Analysis of Saliva or Buccal Mucosa Samples From Patients With Embryonal or Alveolar Rhabdomyosarcoma (NCT03296371) | Children's Oncology Group | 2017-10-23 |