| REVIVE (Response to the Ebola Virus Vaccine) (NCT05992480) | Tulane University | 2025-12-01 |
| The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 1) (NCT07303738) | Boston Children's Hospital | 2025-12-01 |
| Ganagliflozin on the Progression of Kidney Disease in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease (NCT07116928) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2025-11-30 |
| Threatened Preterm Labour: Vaginal Progesterone Versus Nifedipine (NCT07649668) | Dr Mudassar Saeed Pansota | 2025-11-30 |
| Clinical Study on the Effect of Tegileridine on Postoperative Pain in Patients Undergoing Abdominal Surgery. (NCT07277153) | Xin Chen | 2025-11-30 |
| Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis (NCT07225361) | Northwestern University | 2025-11-28 |
| A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment (NCT07220538) | Dr. Willmar Schwabe GmbH & Co. KG | 2025-11-28 |
| Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis (NCT07017270) | Unity Health Toronto | 2025-11-27 |
| Phase IV Clinical Study of Sequential Vaccination of Sabin Strain and Wild Strain Inactivated Poliovirus Vaccine (NCT07457060) | Sinovac Biotech Co., Ltd | 2025-11-27 |
| Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV) (NCT06958796) | Camille N. Kotton, MD | 2025-11-27 |
| A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age Without High-Risk Conditions for Severe Coronavirus Disease 2019 (COVID-19) (NCT07266558) | ModernaTX, Inc. | 2025-11-26 |
| Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia (NCT07034690) | Novartis Pharmaceuticals | 2025-11-26 |
| Fluid Administration in Ketoacidosis (DRINK) (NCT06541535) | Centre Hospitalier Universitaire de Nice | 2025-11-26 |
| Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients (NCT07173855) | Scarborough General Hospital | 2025-11-25 |
| Jack Jumper Ant Venom Immunotherapy Long-term Effectiveness Investigation (NCT06935890) | Murdoch Childrens Research Institute | 2025-11-25 |
| Application of Orelabrutinib With or Without CD20 Monoclonal Antibody in Previously Untreated Marginal Zone Lymphoma (NCT07355699) | Beijing Tongren Hospital | 2025-11-25 |
| Clinical Trial to Evaluate the Efficacy and Safety in Concomitant Administration of Macitentan and Dapagliflozin in Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction (HFmrEF and HFpEF) and Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) (NCT07147114) | Gachon University Gil Medical Center | 2025-11-24 |
| A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation (NCT07073950) | AstraZeneca | 2025-11-24 |
| Continuous Glucose Monitoring By DExcom iN PEople Followed for Type 2 DIabeTes on Insulin Therapy in the Kingdom of Saudi Arabia (NCT07603284) | DexCom, Inc. | 2025-11-24 |
| A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK) (NCT07247084) | Eli Lilly and Company | 2025-11-24 |
| Multi-center Randomized Controlled Clinical Study of Shenling Baishu Granule to Prevent the Recurrence of Low-risk Colorectal Adenoma (NCT06930157) | Shanghai Jiao Tong University School of Medicine | 2025-11-24 |
| 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients (NCT07325240) | Mayo Clinic | 2025-11-21 |
| Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants (NCT06971939) | Neurotech Pharmaceuticals | 2025-11-21 |
| Asymptomatic TB With Innovative Modified Short-course Regimens (NCT06153069) | Huashan Hospital | 2025-11-21 |
| Retinal Protective Effects of Novel Finerenone in Patients With Chronic Kidney Disease (NCT07235891) | Alexandria University | 2025-11-20 |
| Tegoprazan Plus Amoxicillin BID vs TID Regimens for H. Pylori Eradication（Frequency Adjusted Same-dose Therapy for H. Pylori） (NCT07242443) | First People's Hospital of Hangzhou | 2025-11-20 |
| Efficacy and Safety of NVX-CoV2705 (NCT07086222) | Novavax | 2025-11-20 |
| Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction (NCT07178145) | University of Virginia | 2025-11-20 |
| Urinary Proteomics to Guide Early Intervention to Prevent Complications in Type 2 Diabetes - a Feasibility Study (NCT06954090) | Steno Diabetes Center Copenhagen | 2025-11-20 |
| Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure (NCT06979726) | University of Florida | 2025-11-20 |
| Effectiveness of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitor Initiation Before Percutaneous Coronary Intervention on Acute Myocardial Infarction Patients (NCT06683131) | The Affiliated Hospital of Xuzhou Medical University | 2025-11-20 |
| Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery (NCT07131592) | Massachusetts General Hospital | 2025-11-18 |
| Remifentanil Versus Rocuronium for Optimizing Video Laryngoscopy-assisted Tracheal Intubation (NCT06564857) | Nordsjaellands Hospital | 2025-11-17 |
| Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study (NCT07222072) | The Cleveland Clinic | 2025-11-15 |
| Comparison of Convective Water Vapor Ablation (Convective Water Vapor Energy, WAVE™) With the Rezum™ System Versus Holmium Laser Enucleation of the Prostate (HoLEP) Versus Bipolar Transurethral Resection of the Prostate (TUR-P) in Patients With Benign Prostatic Syndrome (BPS) - A Randomized Study (NCT07204002) | Medical University of Graz | 2025-11-15 |
| A Lactation Study in Women Receiving Treatment With Ozanimod (NCT06181630) | Bristol-Myers Squibb | 2025-11-15 |
| Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness (NCT07148232) | University of California, San Francisco | 2025-11-14 |
| Termination of Pregnancy in Previous Scarred Uterus: PGE1 Versus Cervical Folleys (NCT07604051) | Dr Mudassar Saeed Pansota | 2025-11-13 |
| Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures (NCT07145346) | University of California, Irvine | 2025-11-13 |
| Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After Percutaneous Coronary Intervention (PROMOTE) (NCT06916520) | J.P.S Henriques | 2025-11-13 |
| Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) Study (NCT07287137) | Henry M. Jackson Foundation for the Advancement of Military Medicine | 2025-11-12 |
| Remimazolam vs Propofol in Laser Burn Cases (NCT07213544) | Medical University of South Carolina | 2025-11-12 |
| Pre-discharge Influenza Vaccination in Patients Hospitalized for Acute Cardiac Conditions (NCT07617376) | Wroclaw Medical University | 2025-11-12 |
| Intravenous Thrombolysis Combined With Tirofiban in Acute Ischemic Stroke (NCT07290751) | Beijing Anzhen Hospital | 2025-11-11 |
| Low-intensity Shockwave Therapy Versus Solifenacin for the Treatment of Overactive Bladder in Women (NCT07473310) | Mansoura University | 2025-11-11 |
| Study of Growth and Bone Mineral Density in Children With Atopic Dermatitis (AD) Treated With Dupilumab (NCT07187089) | Regeneron Pharmaceuticals | 2025-11-11 |
| Prospective Multicenter Real-world Study of Surufatinib in Patients With Advanced Neuroendocrine Neoplasms (NCT07272512) | Shanghai Zhongshan Hospital | 2025-11-11 |
| The Treatment of Liver Injury After Liver Resection With Polyene Phosphatidylcholine (NCT07150624) | Anhui Provincial Hospital | 2025-11-10 |
| Ketorolac Use and Fresh Embryo Transfer Outcomes (NCT07185724) | Jessica D. Kresowik | 2025-11-08 |
| Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA For Enhancing Facial Skin Quality in Individuals Over the Age of 30 (NCT07376148) | Instituto de Oftalmología Fundación Conde de Valenciana | 2025-11-07 |
| PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis (NCT06902740) | Peking Union Medical College Hospital | 2025-11-07 |
| Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device (NCT07225348) | Skincare Physicians of Chestnut Hill | 2025-11-07 |
| 45th Multicenter Airway Research Collaboration (NCT07166939) | Massachusetts General Hospital | 2025-11-07 |
| Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients (NCT06903819) | Texas Tech University Health Sciences Center | 2025-11-06 |
| Efficacy and Safety Trials of Yangxinshi Tablets in the Treatment of Patients With Coronary Heart Disease Complicated by Cardiac Dysfunction (NCT07110415) | SPH Qingdao Growful Pharmacetical Co.,Ltd | 2025-11-06 |
| The Nonirritating Concentrations of Midazolam, Ketamine, and Ondansetron (NCT07103720) | Mayo Clinic | 2025-11-05 |
| MenB-FHbp or MenACWY-TT/MenB-FHbp Vaccine in MenB-4C Primed Young Adults (NCT07197762) | Emory University | 2025-11-04 |
| Mexidol® Safety and Efficacy in Treatment of Hyperacute and Acute Ischemic Stroke (NCT07575984) | Pharmasoft | 2025-11-04 |
| Preoperative BOTOX® Injection for Large Ventral Hernia Repair (NCT07220382) | The Cleveland Clinic | 2025-11-03 |
| Adjunctive Topical Melatonin Gel in Non-Surgical Periodontal Therapy for Periodontitis (NCT07605767) | Liaquat College of Medicine and Dentistry | 2025-11-03 |
| Suzetrigine vs Norco-postoperative Mohs Pain (NCT07575230) | Baylor Research Institute | 2025-11-03 |
| Effectiveness of Interventional Therapy for Non-Flow-Limiting Vulnerable Plaques (NCT06855537) | Beijing Anzhen Hospital | 2025-11-03 |
| Levothyroxine Dosing in Neonatal Congenital Hypothyroidism (NCT07754370) | Menoufia University | 2025-11-02 |
| Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients (NCT06023043) | Children's Hospital Los Angeles | 2025-11-01 |
| Gentle Touch for Post-Mastectomy Lymphedema (NCT07257679) | I.R.C.C.S. Fondazione Santa Lucia | 2025-11-01 |
| Vericiguat and Reverse Remodeling Indices in Heart Failure (NCT07405944) | University Medical Centre Ljubljana | 2025-11-01 |
| Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma (NCT07209410) | Insight Eyecare Specialties, Inc. dba Vision Source Eyecare, | 2025-11-01 |
| Inter-semispinal Fascial Plane Block (ISPB) Versus Erector Spinae Plane Block (ESPB) in Posterior Cervical Spine Surgery (NCT07340801) | Fayoum University | 2025-11-01 |
| Effectiveness of Systane PRO for Mild to Moderate Dry Eye Disease (NCT07639034) | Gordon Schanzlin New Vision | 2025-11-01 |
| Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial (NCT07214701) | Assiut University | 2025-11-01 |
| Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures (NCT07225101) | University of Michigan | 2025-11-01 |
| Ketamine for the Treatment of Refractory Status Epilepticus (NCT07177235) | Thomas Jefferson University | 2025-11-01 |
| Normal Saline Versus Ringer's Lactate for Initial Fluid Resuscitation in Sepsis (NCT07240701) | Egemen Yildiz | 2025-11-01 |
| DARA-MVI Study (Daratumumab for Microvascular Inflammation in Kidney Transplantation) (NCT07274462) | University Hospital, Martin | 2025-11-01 |
| Sacubitril/Allisartan for Hypertensive Patients With Overweight or Obesity (NCT07241338) | Jing Liu | 2025-11-01 |
| Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work (NCT07266948) | Southern College of Optometry | 2025-11-01 |
| Cerebellum-based Imaging Neural Markers for Antipsychotic Response (NCT07483294) | Northwell Health | 2025-11-01 |
| Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis (NCT07316582) | Al-Azhar University | 2025-11-01 |
| Evaluation of Two Different Regimens of the Antiarrhythmic Drug Amiodarone to Maintain Normal Sinus Rhythm After Electrical Cardioversion in Patients With Persistent Atrial Fibrillation (NCT07273994) | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 2025-11-01 |
| Hemodynamic and Cardiac Effects of Dexmedetomidine Versus Fentanyl by Intravenous Infusion as Adjuncts to General Anesthesia in Patients Undergoing Major Abdominal Cancer Surgeries. (NCT07214714) | Assiut University | 2025-11-01 |
| Comparing the Efficacy of Oral Fluconazole Versus Oral Itraconazole in Treating Resistant Tinea Corporis (NCT07342153) | Urooj Fatima | 2025-11-01 |
| Efficacy of Plasma Rich in Growth Factors (PRGF) in the Treatment of Foot Ulcers in Diabetic Patients With Peripheral Arterial Disease (NCT06952998) | Biotechnology Institute IMASD | 2025-11-01 |
| Cyclosporine Or Methotrexate for Pediatric Alopecia Areata: Routine Clinical Care Effectiveness Study (NCT07381556) | Erasmus Medical Center | 2025-11-01 |
| PLLA and CaHA-R for Aesthetic Rejuvenation (NCT07202117) | Erevna Innovations Inc. | 2025-11-01 |
| The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty (NCT06489626) | F. Johannes Plate | 2025-11-01 |
| Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic Hernia (NCT07247240) | Asan Medical Center | 2025-11-01 |
| De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia (NCT05213676) | The University of Texas Health Science Center, Houston | 2025-11-01 |
| Fengliao Changweikang for Diarrhea-predominant Irritable Bowel Syndrome: N-of-1 Trial (NCT07061184) | Peking Union Medical College Hospital | 2025-11-01 |
| Effects of Energy Drinks on Cardiovascular Endpoints (NCT07212803) | University of the Pacific | 2025-11-01 |
| Empagliflozin Versus Statins in Non-Alcoholic Fatty Liver Disease (NCT07180745) | Badr University | 2025-11-01 |
| Clinical Trial to Evaluate the Efficacy and Safety of DA-5218 in Patients With Type 2 Diabetes (NCT07229534) | Dong-A ST Co., Ltd. | 2025-11-01 |
| Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell Lymphoma (NCT07270835) | The First Affiliated Hospital of Soochow University | 2025-11-01 |
| The Effects of Clostridium Butyricum on Adverse Events During Adjuvant Chemotherapy for Colorectal Cancer (NCT07152886) | The Affiliated Hospital of Qingdao University | 2025-10-31 |
| Single-stage Pulmonary Vein Isolation Combined With Percutaneous Left Atrial Appendage Occluder Implantation in Patients With Recent Onset Ischemic Stroke and Atrial Fibrillation (NCT06212674) | Medical University of Silesia | 2025-10-31 |
| Extended Dosing Intervals Trial for Oral Cholera Vaccine, Kenya (NCT07487077) | Albert B. Sabin Vaccine Institute | 2025-10-31 |
| Use of Tacrolimus and MTOR Inhibitors With Anticipatory Therapy vs. Tacrolimus and Mycophenolic Acid With Universal Prophylaxis in Renal Recipients at High Risk of Posttransplant Cytomegalovirus. (NCT07203664) | Hospital Universitario La Paz | 2025-10-30 |
| Letermovir Prophylaxis Duration Guided by CMV-Specific T-cell Monitoring After Allo-HSCT. (NCT07569653) | WeiShi | 2025-10-30 |
| Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination (NCT06862739) | Nabiqasim Industries (Pvt) Ltd | 2025-10-30 |
| Intracervical Vasopressin (NCT07102615) | Prisma Health-Upstate | 2025-10-30 |
| Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke (NCT07301372) | The Affiliated Hospital of Xuzhou Medical University | 2025-10-30 |