| Perineural Dexamethasone, Dexmedetomidine, or Their Combination to Reduces Rebound Pain After Supraclavicular Brachial Plexus Block (NCT07299877) | Al-Azhar University | 2025-12-28 |
| Effect of Single Dose Intravenous Magnesium Sulfate on Postoperative Analgesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy (NCT07328893) | Tata Main Hospital | 2025-12-27 |
| Anrikefon-based Patient-controlled Intravenous Analgesia After Laparoscopic Surgery (NCT07246785) | Peking University First Hospital | 2025-12-25 |
| A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI) (NCT07311551) | Bhavya Bhavya, MD | 2025-12-24 |
| Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in Cytomegalovirus Infection in Lung Transplant Recipients (NCT07235683) | University Health Network, Toronto | 2025-12-24 |
| Health Benefits of Nutraceutical Supplementation in Older Adults. (NCT07534878) | GPLIFE HEALTHCARE PRIVATE LIMITED | 2025-12-24 |
| Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs) (NCT05962541) | University of Roma La Sapienza | 2025-12-22 |
| Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics (NCT07300878) | Pakistan Institute of Medical Sciences | 2025-12-22 |
| Effect of Pirfenidone on TA Fibrosis (NCT07325357) | Shanghai Zhongshan Hospital | 2025-12-20 |
| Early Administration of PCSK9 Inhibitors After Thrombectomy for Atherosclerotic Acute Ischemic Stroke: A Randomized Controlled Trial (NCT07295366) | The Affiliated Hospital of Xuzhou Medical University | 2025-12-20 |
| Anesthetic Effectiveness of Lidocaine Versus Articaine in Dentistry (NCT07231614) | Universidad Austral de Chile | 2025-12-20 |
| Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares (NCT07346079) | Massachusetts General Hospital | 2025-12-20 |
| Immunogenicity and Safety of Sequential 2vHPV-9vHPV Vaccination in Girls Aged 9-14 Years (NCT07281677) | Zhejiang Provincial Center for Disease Control and Prevention | 2025-12-20 |
| A Multicenter Randomized Controlled Trial of Echocardiography-Guided Atrial Septal Defect Closure Performed in a Mobile Surgical Unit (NCT07273227) | China National Center for Cardiovascular Diseases | 2025-12-19 |
| Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS (NCT07308574) | Alexion Pharmaceuticals, Inc. | 2025-12-19 |
| Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis (NCT07217405) | Mayo Clinic | 2025-12-19 |
| Low-Dose Tenecteplase for Acute Ischemic Stroke Treatment in Aging Patients (NCT07294209) | Southwest Hospital, China | 2025-12-19 |
| OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa (NCT06967519) | Yale University | 2025-12-18 |
| Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease (NCT07058155) | The Cleveland Clinic | 2025-12-17 |
| Immunogenicity and Safety PCV-20 of the Vaccine Administered During an Acute Febrile Illness in Adults (NCT06822907) | Centre Hospitalier Universitaire de Saint Etienne | 2025-12-17 |
| Clinical Study of Equivalent Doses of Oxycodone or Tegileridine on Patients Undergoing Gynecological Laparoscopic Hysterectomy (NCT07326683) | Xin Chen | 2025-12-17 |
| Digoxin After Acute Heart Failure (DIG-DICA) (NCT07321509) | Hospital General de Agudos "Dr. Cosme Argerich" | 2025-12-16 |
| Gabapentin And Breast Surgery Decision Architecture Randomization Trial (GABS-DART) Protocol (NCT07308717) | Memorial Sloan Kettering Cancer Center | 2025-12-16 |
| Effect of Misoprostol on Fluid Deficit Volume in Hysteroscopic Myomectomy (NCT07286188) | Northwestern University | 2025-12-16 |
| Clinical Performance of Nobel N1 System (NCT07280260) | Louisiana State University Health Sciences Center in New Orleans | 2025-12-15 |
| Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression (NCT07026461) | Region Örebro County | 2025-12-15 |
| Inhaled Sedation in Critically Ill Patients (NCT07000526) | Instituto de Investigación Hospital Universitario La Paz | 2025-12-15 |
| Switching From Xiidra to TRYPTYR (NCT07267481) | Southern College of Optometry | 2025-12-15 |
| Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based Treatment (NCT07697287) | McMaster University | 2025-12-15 |
| Prevention of Delayed Post-polypectomy Bleeding by Endoscopic Sucralfate Spray in High-risk Patients: A Randomized Controlled Trial (NCT07257926) | National Cheng-Kung University Hospital | 2025-12-15 |
| Investigator Initiated Trial Using Dry Eye Surveys to Evaluate and Better Understand FDA Approved Acoltremon Treatment for Dry Eye Disease in Real World Treatment Settings (DESERT) (NCT07281950) | Center for Sight Las Vegas | 2025-12-15 |
| A Study on Nausea and Vomiting Caused by T-DXd in Breast Cancer Patients (NCT07254416) | Tianjin Medical University Cancer Institute and Hospital | 2025-12-15 |
| Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China Population With Uncontrolled Type 2 Diabetes on Oral Agents (NCT07307235) | Shanghai Zhongshan Hospital | 2025-12-13 |
| Comparing Treatment of Knee Osteoarthritis With Triamcinolone Injections Using 40mg With Landmark Guidance and 20mg With Ultrasound Guidance (NCT07544576) | Sosi Dzhugarian | 2025-12-12 |
| Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses (NCT07510620) | Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists | 2025-12-12 |
| Effectiveness of mRNA-1273 Variant-Containing Vaccine Formulation Against Severe Outcomes in Adults Aged 50-64 Years Without Risk Factors for Severe COVID-19 (NCT07279766) | Tor Biering-Sørensen | 2025-12-11 |
| A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS) (NCT07223723) | Biogen | 2025-12-11 |
| Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect? (NCT07109245) | Centre for Addiction and Mental Health | 2025-12-11 |
| Efficacy and Tolerability of Sucrosomial® Iron vs Ferric Maltol in Iron Deficient Women (NCT07308769) | Pharmanutra S.p.a. | 2025-12-11 |
| C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics (NCT07220356) | Johns Hopkins University | 2025-12-10 |
| A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL (NCT07172893) | HealthTech Wound Care | 2025-12-10 |
| A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese (NCT07326111) | University of Bonn | 2025-12-09 |
| Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study) (NCT07268547) | Sarasota Memorial Health Care System | 2025-12-09 |
| Pilot Study of Fisetin to Improve Fatigue Among Older Adult Cancer Survivors (NCT06819254) | Wake Forest University Health Sciences | 2025-12-09 |
| Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia (NCT07284290) | Virginia Commonwealth University | 2025-12-08 |
| PRIMA-HF: Predicting Myocardial Recovery in Heart Failure Using Cardiac Imaging HAI-HF: High Dosing vs. Standard Dosing Adenosine During Myocardial Perfusion in Heart Failure (NCT07243119) | Gødstrup Hospital | 2025-12-08 |
| Rivastigmine as an Antidote for Clozapine and Other Anticholinergic-Induced CNS Depression and Delirium: A Study of 100 Cases (NCT07545382) | Alexandria University | 2025-12-08 |
| High Dose Eylea for Proliferative Diabetic Retinopathy Outcomes (NCT07118670) | Edward Wood, MD | 2025-12-08 |
| Evaluating RELiZORB Use for the Treatment of Feeding Intolerance in Adults With Moderate to Severe Acute Pancreatitis (NCT07583342) | Northwell Health | 2025-12-08 |
| Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIAL (NCT07554820) | Shaikh Zayed Hospital, Lahore | 2025-12-06 |
| Impact of FLU Vaccination on Nasal Resident Memory Immune Responses and Peripheral Respiratory-tropic Memory Immune Responses (NCT06824779) | Centre Hospitalier Universitaire de Saint Etienne | 2025-12-05 |
| Efficacy of Top-down Therapy With Mirikizumab Versus Standard of Care With Azathioprine in Patients With Newly Diagnosed Moderate-to-severe Ulcerative Colitis (NCT07235904) | University Hospital Schleswig-Holstein | 2025-12-05 |
| Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version (NCT07092527) | University of California, San Diego | 2025-12-05 |
| Pasteurised Donor Human Milk Supplementation for Term Babies (NCT06993103) | The University of Queensland | 2025-12-04 |
| Romosozumab and Denosumab, Alone or Combined, in Postmenopausal Osteoporosis (NCT07283887) | National Taiwan University Hospital | 2025-12-03 |
| Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases Under Immunomodulators (NCT07280741) | University of Sao Paulo General Hospital | 2025-12-02 |
| Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities (NCT07303582) | Oxford University Hospitals NHS Trust | 2025-12-02 |
| Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome (NCT07277257) | Center For Sight | 2025-12-02 |
| Treating Toddler Obesity by Treating the Parent/Caregiver Obesity With Weight Loss Medications (NCT06768320) | Loma Linda University | 2025-12-01 |
| Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS) (NCT07268222) | Laikο General Hospital, Athens | 2025-12-01 |
| Preoperative Maltodextrin's Effect on Cardiac Function in Cardiac Surgery (NCT05188222) | Jewish General Hospital | 2025-12-01 |
| Switching From Restasis to TRYPTYR (NCT07267299) | Southern College of Optometry | 2025-12-01 |
| Individualized Application of Anti-Thymocyte Globulin(ATG)in Unrelated Donor Hematopoietic Stem Cell Transplantation (NCT07648992) | Daihong Liu | 2025-12-01 |
| Interleukin-23 Monoclonal Antibody for Inflammatory Bowel Disease: Efficacy and Safety (NCT07216014) | Sixth Affiliated Hospital, Sun Yat-sen University | 2025-12-01 |
| GLP-1 Receptor Agonists in Non-diabetic Patients With Psoriatic Arthritis (NCT07251556) | Chinese University of Hong Kong | 2025-12-01 |
| Bilateral Erector Spinae Plane Block Versus Bilateral Quadratus Lumborum Plane Block for Postoperative Anaelgesia After Lumbar Spine Surgery (NCT07517822) | Ain Shams University | 2025-12-01 |
| Phase 4 Study of Laybon Tab. in Knee Osteoarthritis (NCT07203547) | Mather's Pharm. Co., Ltd. | 2025-12-01 |
| Short-Term Dual Antiplatelet Therapy With Early Transi-tion to Low-dose Antiplatelet Monotherapy Using Ti-cagRelor in Chronic Coronary Artery Disease (NCT07080684) | University of Messina | 2025-12-01 |
| Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery (NCT07265128) | Yonsei University | 2025-12-01 |
| Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing (NCT07326553) | BioXTek | 2025-12-01 |
| Dose-escalation of Rectal Indomethacin for Preventing PEP (NCT07247682) | The First Affiliated Hospital of Anhui Medical University | 2025-12-01 |
| Niaoduqing Granules in Older Adults With Impaired Kidney Function (NCT07741292) | Huashan Hospital | 2025-12-01 |
| Perioperative Colchicine for TKA (NCT06936709) | Geisinger Clinic | 2025-12-01 |
| Use of PRP for the Healing of Grade III Ulcers (NCT07255391) | Hospital Mutua de Terrassa | 2025-12-01 |
| Sequential rhTPO and Eltrombopag Following Glucocorticoids for Severe Adult ITP (NCT07189910) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-12-01 |
| Total Intravenous and Balanced Anesthesia in Diabetic Patients Undergoing Video-Assisted Thoracoscopy (NCT07496593) | Ain Shams University | 2025-12-01 |
| Does it Matter the Volume of Injectate on the Outcome of Ultrasound-guided Perineural Injection for Carpal Tunnel Syndrome (NCT07283874) | Assiut University | 2025-12-01 |
| Paracetamol and Mannitol Injection and Postoperative Delirium (NCT07235995) | Xiangya Hospital of Central South University | 2025-12-01 |
| Optimising Pacing Therapy, Integrated Medical Therapy, and Catheter AbLation for Atrial Fibrillation in Heart Failure Trial (NCT07238452) | University of British Columbia | 2025-12-01 |
| Efficacy of Topical Apraclonidine for the Treatment of Ocular Synkinesis (NCT05167760) | University of Alabama at Birmingham | 2025-12-01 |
| Clinical Trial to Evaluate the Efficacy of Probit-Based Triple Therapy for Helicobacter Pylori Eradication (NCT07115173) | Samsung Medical Center | 2025-12-01 |
| Developing a Physiology-Pharmacodynamic Model of Rocuronium Dose and Cardiac Output to Investigate the Onset Time of Neuromuscular Relaxation (NCT07168252) | Clare Hayes-Bradley | 2025-12-01 |
| Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients (NCT07391579) | Mansoura University | 2025-12-01 |
| Postoperative Intravenous Ferric Derisomaltose for Prevention of Long-term Anemia After Cardiac Surgery (NCT07238972) | Yonsei University | 2025-12-01 |
| Effect of Clonidine Additive to suprascapular_ Costoclavicular Versus Standard Interscalene Block in Arthroscopic Shoulder Surgeries (NCT07256938) | Assiut University | 2025-12-01 |
| A Trial of Shengmai Liquid for Long COVID Fatigue. (NCT06980636) | Beijing University of Chinese Medicine | 2025-12-01 |
| Very Low Dose Prednisolone on Newly Diagnosed Rheumatoid Arthritis (NCT07252271) | Chinese University of Hong Kong | 2025-12-01 |
| Effect of Itopride on Semaglutide Gastroparesis (NCT07254715) | Ain Shams University | 2025-12-01 |
| Comparison of Glucocorticoid Tapering Schedules in Rheumatoid Arthritis (NCT07227428) | Seoul National University Hospital | 2025-12-01 |
| Role of Nerve Block in Management of Multiple Rib Fractures (NCT06958549) | Assiut University | 2025-12-01 |
| Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care (NCT07236944) | Uppsala University | 2025-12-01 |
| Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy (NCT06632184) | Instituto Mexicano del Seguro Social | 2025-12-01 |
| BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis (NCT07237308) | Yonsei University | 2025-12-01 |
| Phase 4 Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Chinese Participants With Generalized Myasthenia Gravis (NCT07246564) | UCB Biopharma SRL | 2025-12-01 |
| Comparative Evaluation of the Performance of Different Thromboplastin Reagents on Prothrombin Time in Situations of Isolated Extrinsic Pathway Factor Deficiency or Liver Damage (NCT06974396) | University Hospital, Strasbourg, France | 2025-12-01 |
| Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of Secukinumab in HS (NCT07261072) | Peking Union Medical College | 2025-12-01 |
| Comparison of Two Treatment Regimens of Helicobacter Pylori Infection (NCT07021729) | Rehman Medical Institute - RMI | 2025-12-01 |
| Effect of Noninvasive Ventilation on Physical Activity and Inflammation in COPD Patients (NCT01037387) | Hospital Universitario La Paz | 2025-12-01 |
| "Effect of Ibuprofen on Acute Inflammatory Response After One-Stage Periodontal Therapy" (NCT07459049) | University of Baghdad | 2025-12-01 |
| Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE） (NCT07063108) | Chinese PLA General Hospital | 2025-12-01 |