| DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2) (NCT05566795) | Day One Biopharmaceuticals, Inc. | 2023-02-27 |
| Assessment of the Safety and Efficacy of BRM421 Ophthalmic Solutions in Dry Eye Subjects. (NCT05695781) | BRIM Biotechnology Inc. | 2023-02-27 |
| General Decolonization With Octenisan® Set Before Elective Orthopedic Surgery (NCT05647252) | Balgrist University Hospital | 2023-02-27 |
| A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata (NCT05723198) | Eli Lilly and Company | 2023-02-27 |
| Clinical Impact and Utility of Digital Health Solutions in Participants Receiving Systemic Treatment in Clinical Practice (NCT05694013) | Hoffmann-La Roche | 2023-02-27 |
| Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness (NCT06138613) | Vanda Pharmaceuticals | 2023-02-27 |
| A Long-term Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia (NCT05687071) | Otsuka Pharmaceutical Co., Ltd. | 2023-02-27 |
| Study to Evaluate NRCT-101SR in Adult Attention Deficit Hyperactivity Disorder (ADHD) (NCT05683249) | Neurocentria, Inc. | 2023-02-25 |
| Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis (NCT05697471) | Far Eastern Memorial Hospital | 2023-02-25 |
| BOTOX® vs. XEOMIN® for Chronic Migraine (NCT05598723) | Naval Medical Center Camp Lejeune | 2023-02-24 |
| Effect on Post-operative Pain of Tranexamic Acid Injection During Shoulder Surgery (NCT05302986) | Elsan | 2023-02-24 |
| A Clinical Trial to Evaluate the Efficacy and Safety of Co-administration of DWC202206 and DWC202207 in Patients With Concomitant Hypertension and Hyperlipidemia (NCT05643508) | Daewoong Pharmaceutical Co. LTD. | 2023-02-23 |
| RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease (NCT05392894) | King's College Hospital NHS Trust | 2023-02-23 |
| Fenofibrate Combined With Ursodeoxycholic Acid in Subjects With Primary Biliary Cholangitis (NCT05751967) | Xijing Hospital of Digestive Diseases | 2023-02-22 |
| An Extension Study of JR-141 to Evaluate the Long-term Safety and Efficacy in MPS II (Hunter Syndrome) Subjects (NCT05594992) | JCR Pharmaceuticals Co., Ltd. | 2023-02-22 |
| A Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa (HS) (NCT05620836) | Incyte Corporation | 2023-02-22 |
| Safety and Effectiveness of Evinacumab for the Treatment of Homozygous Familial Hypercholesterolemia (NCT05611528) | Daniel Gaudet | 2023-02-21 |
| A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection (NCT05784129) | Janssen Research & Development, LLC | 2023-02-21 |
| Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Children 4-7 Years of Age (NCT05741476) | DBV Technologies | 2023-02-21 |
| PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE) (NCT05419193) | Beijing Tiantan Hospital | 2023-02-21 |
| Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects (NCT05753189) | LENZ Therapeutics, Inc | 2023-02-21 |
| Divided or Single Exposure (DOSE) Study (NCT05459402) | University of Maryland, Baltimore | 2023-02-21 |
| A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD) (NCT05724199) | Amgen | 2023-02-21 |
| A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss (NCT05382338) | Children's Oncology Group | 2023-02-20 |
| Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA (NCT05797077) | Sixth Affiliated Hospital, Sun Yat-sen University | 2023-02-20 |
| A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Antiretroviral Therapy (ART) (MK-8591A-051) (NCT05631093) | Merck Sharp & Dohme LLC | 2023-02-20 |
| Neoadjuvant Concomitant Modulated Electro-hyperthermia in HER2-negative Breast Cancer (NCT05889390) | Semmelweis University | 2023-02-20 |
| Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome (NCT06013319) | Zhiming Jiang | 2023-02-20 |
| ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer (NCT05815082) | Sixth Affiliated Hospital, Sun Yat-sen University | 2023-02-20 |
| Efficacy,Immunogenicity and Safety of COVID-19 Vaccine , Inactivated Booster Dose in Adults Aged 18 Years and Above (NCT05156632) | Sinovac Research and Development Co., Ltd. | 2023-02-20 |
| Steroid Eye Drops in Chronic Central Serous Chorioretinopathy (NCT05633576) | Radboud University Medical Center | 2023-02-19 |
| Phase Ⅲ Clinical Study of Quadrivalent Influenza Virus Split Vaccine (NCT05642078) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2023-02-18 |
| Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation (NCT05679024) | Region Stockholm | 2023-02-17 |
| Fenofibrate for Compensated Cirrhosis Patients With Primary Biliary Cholangitis (NCT05749822) | Xijing Hospital of Digestive Diseases | 2023-02-17 |
| A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-052) (NCT05630755) | Merck Sharp & Dohme LLC | 2023-02-17 |
| Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C (NCT05905926) | Ardelyx | 2023-02-17 |
| PD-1 Antibody Combined With mXELIRI Versus mXELIRI in the Second-line Setting for ESCC (NCT05737563) | Sun Yat-sen University | 2023-02-17 |
| To Demonstrate the Superiority of IMP (0.3% and 1% OPA-15406 Ointment) Versus the Vehicle in Pediatric Patients with AD (NCT05650320) | Otsuka Beijing Research Institute | 2023-02-17 |
| Acceptance Commitment Therapy for Caregivers of People with Memory Loss (NCT05749939) | Utah State University | 2023-02-16 |
| Stent Implantation Versus Medical Therapy for Idiopathic IntracraniaL Hypertension (SIMPLE) (NCT05707442) | Beijing Tiantan Hospital | 2023-02-16 |
| Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF ) (NCT05668676) | Assistance Publique - Hôpitaux de Paris | 2023-02-16 |
| A Study of QL1706 in Combination With Chemotherapy in PD-L1-Negative Non-small Cell Lung Cancer (NCT05690945) | Qilu Pharmaceutical Co., Ltd. | 2023-02-15 |
| A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE (NCT05702034) | Janssen Research & Development, LLC | 2023-02-15 |
| Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome (NCT05674539) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2023-02-15 |
| Segmentectomy for Ground Glass-dominant Invasive Lung Cancer (ECTOP-1012) (NCT05717803) | Fudan University | 2023-02-15 |
| Feasibility of Gallium-68-tilmanocept PET/CT for Sentinel Lymph Node Detection in Endometrial Cancer (NCT05446324) | UMC Utrecht | 2023-02-15 |
| Bioequivalence Study of Two Products of Apremilast 30 mg Tablets in Healthy, Adult, Human Subjects (NCT06084663) | Humanis Saglık Anonim Sirketi | 2023-02-15 |
| Durvalumab Plus Tremelimumab as First-line Treatment in Chinese Patients With uHCC (NCT05557838) | AstraZeneca | 2023-02-15 |
| Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation (NCT04711109) | Alliance for Clinical Trials in Oncology | 2023-02-14 |
| Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD (NCT05711940) | COMPASS Pathways | 2023-02-14 |
| A Study of IBI311 in Subjects With Active Thyroid Eye Disease (NCT05795621) | Innovent Biologics (Suzhou) Co. Ltd. | 2023-02-14 |
| A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77) (NCT05722015) | Merck Sharp & Dohme LLC | 2023-02-14 |
| This Study Will Compare the Efficacy and Safety of SCT510A Administered by Intravitreal Injection (IVT) With Ranibizumab in Patients With wAMD (NCT05480293) | Sinocelltech Ltd. | 2023-02-14 |
| A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures (NCT05667142) | Xenon Pharmaceuticals Inc. | 2023-02-14 |
| Safety and Immunogenicity of V116 in Adults With Increased Risk for Pneumococcal Disease (V116-008) (NCT05696080) | Merck Sharp & Dohme LLC | 2023-02-13 |
| Comparison of Complarate® (Tocilizumab Biosimilar) and Actemra® in Patients With Rheumatoid Arthritis (NCT06475508) | AO GENERIUM | 2023-02-13 |
| Efficacy and Safety of Azelastine +Mometasone , Nasal Spray, 140 mcg + 50 mcg, (Sandoz d.d., Slovenia) and Momat Rino Advance, Nasal Spray, 140 mcg + 50 mcg, (Glenmark, India) Administered as a Monotherapy to Patients With Seasonal Allergic Rhinitis. (NCT05590598) | Sandoz | 2023-02-13 |
| A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (NCT05685238) | Novo Nordisk A/S | 2023-02-13 |
| A Confirmatory Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia (NCT05683340) | Otsuka Pharmaceutical Co., Ltd. | 2023-02-13 |
| Use of Essential Oils as Natural Therapies (NCT05777525) | University of Extremadura | 2023-02-11 |
| Steroid-Eluting Stent Implant for the Treatment of Radiation-Related Sinusitis (NCT05757479) | Sun Yat-sen University | 2023-02-11 |
| Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles (NCT06124235) | University of Baghdad | 2023-02-10 |
| A Study to Evaluate IBI112 in the Treatment of Psoriasis With Moderate to Severe Plaque Psoriasis (NCT05645627) | Innovent Biologics (Suzhou) Co. Ltd. | 2023-02-10 |
| Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies (NCT05682378) | Novartis Pharmaceuticals | 2023-02-10 |
| SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer (NCT05451004) | Canadian Cancer Trials Group | 2023-02-10 |
| Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma (NCT05605899) | Kite, A Gilead Company | 2023-02-10 |
| Study of Rituximab Monotherapy on Children With New-onset Nephrotic Syndrome: A Randomized Controlled Trial (NCT05734794) | The Children's Hospital of Zhejiang University School of Medicine | 2023-02-09 |
| Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Experiencing a PMR Relapse (NCT05533164) | Sint Maartenskliniek | 2023-02-09 |
| Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep (NCT05458609) | Baylor College of Medicine | 2023-02-09 |
| High-flow Nasal Cannula Oxygenation During Rapid Sequence Induction in Children (NCT05063084) | Assistance Publique - Hôpitaux de Paris | 2023-02-09 |
| Study of Obeldesivir in Nonhospitalized Participants With COVID-19 (NCT05715528) | Gilead Sciences | 2023-02-08 |
| A Single-patient Clinical Trial of MAS825 in a Patient With XIAP Deficiency (NCT06309823) | The Hospital for Sick Children | 2023-02-08 |
| A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) (NCT05578976) | Genmab | 2023-02-08 |
| Study to Assess the Efficacy and Safety of STI-1558 in Adult Subjects With Mild or Moderate (COVID-19) (NCT05716425) | Zhejiang ACEA Pharmaceutical Co. Ltd. | 2023-02-08 |
| BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases (NCT04531878) | Children's Hospital of Fudan University | 2023-02-08 |
| Immunonutrition for Diabetic Foot Ulcers (NCT05281562) | Prisma Health-Midlands | 2023-02-08 |
| Pramipexole for Anhedonic Depression (NCT05355337) | Region Skane | 2023-02-08 |
| A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control (NCT05705440) | GlaxoSmithKline | 2023-02-07 |
| Intravesical BCG vs GEMDOCE in NMIBC (NCT05538663) | ECOG-ACRIN Cancer Research Group | 2023-02-07 |
| Clinical Assessment of Injectable Flowable Composite with Giomer Technology Vs High Viscosity Glass Ionomer Restorations in ART for Cancer Patients (NCT05465369) | Cairo University | 2023-02-07 |
| Efficacy and Immunological Evaluation of Telitacicept and Low Dose IL2 in the Treatment of Systemic Lupus Erythematosus (NCT05339217) | Liu Tian | 2023-02-07 |
| A Study of Shengxuening Tablet in the Treatment of Chemotherapy-related Anemia in Hematologic Tumors (NCT05784870) | Zhongnan Hospital | 2023-02-07 |
| Bioequivalence Study of Two Treatments for the Treatment of Plaque Psoriasis (NCT05763082) | Padagis LLC | 2023-02-07 |
| Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma (T-LBL) (NCT05681260) | Children's Cancer Group, China | 2023-02-06 |
| To Demonstrate the Superiority of IMP (1% OPA-15406 Ointment) to the Vehicle in Adult Patients With AD (NCT05667623) | Otsuka Beijing Research Institute | 2023-02-06 |
| A Study to Evaluate Usability of Subcutaneous Auto-injector of CT-P47 in Patients With Active Rheumatoid Arthritis (NCT05725434) | Celltrion | 2023-02-06 |
| ARVAC-A New Recombinant Coronavirus Disease 2019 (COVID-19) Vaccine (NCT05752201) | Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno | 2023-02-06 |
| A Clinical Trial of an Quadrivalent Influenza Virus Subunit Vaccine in Chinese Children Aged 6 to 35 Months (NCT05645900) | Ab&B Bio-tech Co., Ltd.JS | 2023-02-06 |
| Next Generation Ingestible Sensors for Medication Adherence Measurement (NCT05592613) | Brigham and Women's Hospital | 2023-02-06 |
| " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD " (NCT05580510) | Instituto Nacional de Cardiologia Ignacio Chavez | 2023-02-06 |
| Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (NCT05666804) | Novartis Pharmaceuticals | 2023-02-06 |
| A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR (NCT05660447) | Wills Eye | 2023-02-06 |
| Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46) (NCT05609968) | Merck Sharp & Dohme LLC | 2023-02-06 |
| A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes (NCT05691712) | Eli Lilly and Company | 2023-02-05 |
| To Evaluate Safety of Oral Cholera Vaccine Hillchol® (BBV131) (NCT05732766) | Bharat Biotech International Limited | 2023-02-04 |
| Expression-linked and R-ISS-adapted Stratification for First Line Therapy in Multiple Myeloma Patients (NCT05665140) | University Hopsital Schleswig Holstein Campus Lübeck | 2023-02-03 |
| Booster Study of PTX-COVID19-B in Adults Aged 18 Years and Older (NCT05534048) | Everest Medicines (Singapore) Pte. Ltd. | 2023-02-03 |
| Efficacy and Safety of JS002 as Monotherapy in Patients With Primary Hypercholesterolaemia and Mixed Dyslipidemia (NCT05621070) | Shanghai Junshi Bioscience Co., Ltd. | 2023-02-03 |
| Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP) (NCT05653349) | Novartis Pharmaceuticals | 2023-02-03 |
| Clinical Trial for Patients With a Stage IV Childhood Renal Tumor, Comparing Upfront Vincristine, Actinomycin-D and Doxorubicin (Standard Arm) With Upfront Vincristine, Carboplatin and Etoposide (Experimental Arm) (NCT03669783) | Assistance Publique Hopitaux De Marseille | 2023-02-03 |