| NAlmefene Versus Placebo in Addition to Treatment as Usual on Craving in Behavioural Addictions (NCT05540288) | Nantes University Hospital | 2023-03-31 |
| Comparative, Multicenter Study in Subjects with Rheumatoid Arthritis, ALVOFLEX (NCT05842213) | Alvotech Swiss AG | 2023-03-30 |
| Efficacy and Safety of Hemorrane Plus Versus Hemorrane and Versus Placebo in Patients With Uncomplicated Haemorrhoids (NCT05788497) | Faes Farma, S.A. | 2023-03-30 |
| Clinical Study on Adjuvant Therapy of TQB3616 Combined With Endocrine Therapy Compared With Placebo Combined With Endocrine Therapy in Patients With Breast Cancer (NCT05780567) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2023-03-30 |
| Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working (NCT05432791) | National Cancer Institute (NCI) | 2023-03-30 |
| A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus (NCT05707832) | CSPC Ouyi Pharmaceutical Co., Ltd. | 2023-03-30 |
| Evaluation of the Efficacy and Safety of Intravenous Imipenem/Cilastatin/XNW4107 in Comparison With Meropenem in Hospitalized Adults With cUTI Including AP (EudraCT no. 2022-000061-40) (NCT05204368) | Evopoint Biosciences Inc. | 2023-03-30 |
| A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD) (NCT05795699) | Kowa Research Institute, Inc. | 2023-03-30 |
| A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis of the Lumbar Spine (NCT03110523) | Techfields Pharma Co. Ltd | 2023-03-30 |
| Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients (NCT05586971) | LG Chem | 2023-03-30 |
| Ebastine Versus Mebeverine in IBS Patients (NCT05815602) | Guy Boeckxstaens | 2023-03-30 |
| In Vivo Efficacy of Salbutamol (Sandoz) Versus Salbutamol Ventolin (GSK) in Children With Asthma (NCT05884970) | Canisius-Wilhelmina Hospital | 2023-03-30 |
| A Phase 3 Clinical Study to Evaluate Lemzoparlimab for Injection in Combination With Azacitidine (AZA) Versus AZA Monotherapy in Treatment-naïve Patients With Higher-risk Myelodysplastic Syndrome (MDS) (NCT05709093) | TJ Biopharma Co., Ltd. | 2023-03-30 |
| Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. (NCT05727904) | Iovance Biotherapeutics, Inc. | 2023-03-30 |
| A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome (NCT05627557) | Hoffmann-La Roche | 2023-03-29 |
| Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) (NCT06229041) | Peking University Cancer Hospital & Institute | 2023-03-29 |
| Evaluating Novel Therapies in ctDNA Positive GI Cancers (NCT05482516) | Georgetown University | 2023-03-29 |
| A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (NCT05572515) | Janssen Research & Development, LLC | 2023-03-29 |
| A Study of Olanzapine in Patients With Acute Agitation (NCT05803642) | Qilu Pharmaceutical Co., Ltd. | 2023-03-28 |
| Study of Telitacicept in Generalized Myasthenia Gravis (NCT05737160) | RemeGen Co., Ltd. | 2023-03-28 |
| Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease (NCT05732727) | University Hospital, Tours | 2023-03-28 |
| FS-1502 Versus T-DM1 for HER2-Positive Unresectable Locally Advanced or Metastatic Breast Cancer (NCT05755048) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2023-03-28 |
| Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines (NCT05875701) | Novavax | 2023-03-28 |
| Immunosuppressive Treatment in Chronic Virus-Negative Inflammatory Cardiomyopathy (NCT05570409) | LMU Klinikum | 2023-03-28 |
| Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery (NCT04922333) | Wake Forest University Health Sciences | 2023-03-28 |
| Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study ) (NCT05568888) | CSL Behring | 2023-03-28 |
| A Study of mRNA-1283 Injection Compared With mRNA-1273 Injection in Participants ≥12 Years of Age to Prevent COVID-19 (NCT05815498) | ModernaTX, Inc. | 2023-03-28 |
| Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations (NCT06041776) | Betta Pharmaceuticals Co., Ltd. | 2023-03-28 |
| REVErsing Airway Remodelling With Tezepelumab (NCT05651841) | University Hospital, Montpellier | 2023-03-27 |
| A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) (NCT05813288) | Areteia Therapeutics | 2023-03-27 |
| A Study of Adynovate in Previously Treated Chinese Teenagers and Adults With Severe Hemophilia A (NCT05707351) | Takeda | 2023-03-27 |
| Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (NCT05794230) | Sanofi Pasteur, a Sanofi Company | 2023-03-27 |
| Cook´s Balloon Versus Dinoprostone for Labor Induction of Term Pregnancies With Fetal Growth Restriction (NCT05774236) | Hospital Universitario 12 de Octubre | 2023-03-27 |
| Clinical Trail of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021) in Participants Aged 18 Years and Older (NCT05812014) | AIM Vaccine Co., Ltd. | 2023-03-25 |
| A Study of Letermovir (MK-8228) to Evaluate Efficacy and Safety for Prevention of Cytomegalovirus Infection in Chinese Hematopoietic Stem Cell Transplant Recipients (MK-8228-045) (NCT05763823) | Merck Sharp & Dohme LLC | 2023-03-24 |
| To Investigate Efficacy and Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as Reference (NCT06091436) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2023-03-24 |
| Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual Ischemia (NCT05549752) | Hippocration General Hospital | 2023-03-24 |
| Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital (NCT05706727) | KIST Medical and Teaching Hospital | 2023-03-23 |
| To Evaluate the Safety and Efficacy of Meplazumab in Treatment of Post-COVID-19 (NCT05813587) | Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd | 2023-03-23 |
| HU007 in Patients with Dry Eye Syndrome (NCT05743764) | Huons Co., Ltd. | 2023-03-23 |
| A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis (NCT05767047) | Amgen | 2023-03-23 |
| Evaluation of TNF-alpha Antagonists (Infliximab) Withdrawal in Sarcoidosis (NCT05689879) | Assistance Publique - Hôpitaux de Paris | 2023-03-23 |
| HEALEY ALS Platform Trial - Regimen F ABBV-CLS-7262 (NCT05740813) | Merit E. Cudkowicz, MD | 2023-03-23 |
| Feasibility of DPP-4 Inhibitor Therapy on Advanced Hybrid Closed Loop System (NCT06021119) | Ain Shams University | 2023-03-23 |
| A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC) (NCT05714202) | Janssen Research & Development, LLC | 2023-03-23 |
| Vamikibart in Participants With Uveitic Macular Edema (NCT05642325) | Hoffmann-La Roche | 2023-03-23 |
| Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR) (NCT05767034) | Novartis Pharmaceuticals | 2023-03-22 |
| A Phase 3 Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid (NCT05681481) | argenx | 2023-03-22 |
| Prevention of Incisional Hernia With Mesh-suture at Umbilical Trocar Site. (NCT06251583) | Miguel A ngel Garci-a Urena | 2023-03-22 |
| Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (NCT05597280) | Institute of Tropical Medicine, Belgium | 2023-03-22 |
| Pyridostigmine and Amifampridine for Myasthenia Gravis (NCT05919407) | Leiden University Medical Center | 2023-03-22 |
| Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV (NCT05768230) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2023-03-22 |
| Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial (NCT05006482) | University of Rochester | 2023-03-21 |
| Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment Failure (NCT04841096) | Laboratorios Silanes S.A. de C.V. | 2023-03-21 |
| Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT) (NCT05657457) | General Hospital of Shenyang Military Region | 2023-03-21 |
| Intra-arterial Tenecteplase During First Thrombectomy Attempt for Acute Stroke (BRETIS-TNK II) (NCT05657444) | General Hospital of Shenyang Military Region | 2023-03-21 |
| Evaluation of the Effect of Liposomal L-Arg and Vit C Integration on Mitochondrial Function in Patients With Heart Failure (NCT06044194) | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 2023-03-21 |
| Camrelizumab in Combination With Apatinib and Temozolomide as First-line Treatment in Advanced Acral Melanoma (NCT05789043) | Peking University Cancer Hospital & Institute | 2023-03-21 |
| Post-surgical Scars After the Use of CACIPLIQ20 (NCT05528328) | Organ, Tissue, Regeneration, Repair and Replacement | 2023-03-21 |
| Rescue Thrombolysis for Medium Vessel Occlusion (RESCUE-TNK) (NCT05657470) | General Hospital of Shenyang Military Region | 2023-03-21 |
| Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome (NCT05586802) | Georgios Papadakis | 2023-03-21 |
| NATIENS: Optimal Management and Mechanisms of SJS/TEN (NCT02987257) | Vanderbilt University Medical Center | 2023-03-21 |
| Effect of a Healthy Food Voucher on Blood Glucose Control in People With Type 2 Diabetes or Prediabetes (NCT05776420) | Unity Health Toronto | 2023-03-21 |
| Combined Ketamine and Midazolam for Generalized Convulsive Status Epilepticus (NCT05779657) | Sohag University | 2023-03-21 |
| Safety and Efficacy of Intra-arterial Tenecteplase for Noncomplete Reperfusion of Intracranial Occlusions (NCT05499832) | Insel Gruppe AG, University Hospital Bern | 2023-03-21 |
| A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients (NCT05815901) | JW Pharmaceutical | 2023-03-21 |
| Role of the Gut Vascular Barrier and Microbiota in Autism Spectrum Disorders (NCT07450443) | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 2023-03-21 |
| A Study of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy (NCT05769855) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2023-03-21 |
| Maintenance Pembrolizumab at Usual or Low doSE in Non-squamous Lung Cancer: a Non-inferiority Study (NCT05692999) | Gustave Roussy, Cancer Campus, Grand Paris | 2023-03-20 |
| Study of MB-102 (Relmapirazin) and the Use of the MediBeacon® Transdermal GFR Measurement System Using the TGFR Reusable Sensor With Disposable Adhesive Ring (NCT05777174) | MediBeacon | 2023-03-20 |
| Evaluate the Efficacy, Safety, and Pharmacokinetic Profile and Immunogenicity of Subcutaneous Netakimab in Chinese Adult Patients With Active Ankylosing Spondylitis (NCT07277179) | SPH-BIOCAD (HK) Limited | 2023-03-20 |
| A Study to Investigate the Effect of DWP16001 as add-on Therapy to Drug A in Patients With Type 2 Diabetes Mellitus (NCT05466643) | Daewoong Pharmaceutical Co. LTD. | 2023-03-17 |
| Evaluation of the Use of Empagliflozin in Patients with HF with PEF in a Cardiology Outpatient Department (NCT06683053) | Conrado Roberto Hoffmann Filho | 2023-03-17 |
| Fasting Mimicking Diet Program to ImpRovE ChemoTherapy in Hormone Receptor Postive (HR+), HER2- Breast Cancer (NCT05503108) | Leiden University Medical Center | 2023-03-17 |
| A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054) (NCT05766501) | Merck Sharp & Dohme LLC | 2023-03-17 |
| Famitinib in Combination With Camrelizumab and TPC in The First-line Treatment of Immunomodulatory Locally Advanced or Metastatic TNBC. (NCT05760378) | Fudan University | 2023-03-17 |
| Intravenous Tenecteplase Plus EVT Versus EVT Alone on 4.5 to 24 Hours After Basilar Artery Occlusion (NCT05701956) | The First Affiliated Hospital of University of Science and Technology of China | 2023-03-16 |
| Fixed Combination of Dipyrone and Codeine for Controlling Pain After Pelvic-abdominal Surgery (NCT04641338) | Brazilian Clinical Research Institute | 2023-03-16 |
| A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008) (NCT05624554) | Merck Sharp & Dohme LLC | 2023-03-16 |
| Efficacy of Supplement Adjuvant Capecitabine in HR+/HER2- Breast Cancer Patients With High Risks (NCT05212454) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2023-03-15 |
| Fecal Microbiota Transplantation in Clostridioides Difficile Infection First Episode and First Recurrence (NCT05266807) | Benoit Guery | 2023-03-15 |
| Safety and Efficacy of DIDALA Monotherapy in Patients With Type 2 Diabetes Compared With Metformin. (NCT05760456) | Centre of Clinical Pharmacology, Hanoi Medical University | 2023-03-15 |
| Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (NCT05763875) | Novartis Pharmaceuticals | 2023-03-15 |
| Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer (NCT05445778) | AbbVie | 2023-03-15 |
| Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome (NCT05457556) | Children's Oncology Group | 2023-03-15 |
| Ultrasound-Guided Thoracic Paravertebral Block With Steroid and Local Anesthetic for Acute Herpes Zoster: Effects on Pain Control and Prevention of Postherpetic Neuralgia (NCT07349680) | Assiut University | 2023-03-15 |
| Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases (NCT05768490) | Sun Yat-sen University | 2023-03-15 |
| Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis (NCT05201404) | Can-Fite BioPharma | 2023-03-15 |
| Efficacy and Safety of RC28-E Versus Aflibercept (NCT05727397) | RemeGen Co., Ltd. | 2023-03-14 |
| Ramucirumab Plus Pembrolizumab vs Usual Care for Treatment of Stage IV or Recurrent Non-Small Cell Lung Cancer Following Immunotherapy, Pragmatica-Lung Study (NCT05633602) | SWOG Cancer Research Network | 2023-03-14 |
| Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study (NCT05695027) | Columbia University | 2023-03-14 |
| Assessment of Immunogenicity, Safety and Reactogenicity of a Booster Dose of Various COVID-19 Vaccine Platforms in Individuals Primed With Several Regimes. (NCT05812586) | D'Or Institute for Research and Education | 2023-03-14 |
| Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome (NCT05789056) | Quoin Pharmaceuticals | 2023-03-14 |
| Short Versus Long-term Androgen Deprivation Therapy With Salvage Radiotherapy in Prostate Cancer. URONCOR 0624 (NCT05781217) | Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic | 2023-03-14 |
| Repurposing Clinically Approved Drugs for Yaws With an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws) (NCT05764876) | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 2023-03-14 |
| Adjuvant Trastuzumab Plus Neratinib in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer After Neoadjuvant Trastuzumab Plus Pertuzumab (NCT05760612) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2023-03-14 |
| Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers (NCT05063552) | National Cancer Institute (NCI) | 2023-03-13 |
| A Study to Understand the Long-term Safety and Effects of an Experimental Gene Therapy for Duchenne Muscular Dystrophy. (NCT05689164) | Pfizer | 2023-03-13 |
| The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal (NCT07142408) | The Cooper Health System | 2023-03-13 |
| A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy (NCT05696613) | Cerium Pharmaceuticals, Inc. | 2023-03-13 |