| Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents (NCT06120491) | AstraZeneca | 2023-11-21 |
| Effectiveness and Safety of Lebrikizumab Treatment in Adults and Adolescents With Moderate-to-Severe Atopic Dermatitis (NCT05990725) | Almirall, S.A. | 2023-11-20 |
| A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2) (NCT05417516) | Ontario Clinical Oncology Group (OCOG) | 2023-11-20 |
| A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT) (NCT06077864) | Boehringer Ingelheim | 2023-11-20 |
| Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis (NCT06566508) | Mansoura University | 2023-11-20 |
| A Phase III, Active-Controlled Study of SHR-A1811 Versus Trastuzumab Emtansine (T-DM1) in HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy (NCT06126640) | Jiangsu HengRui Medicine Co., Ltd. | 2023-11-20 |
| CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2). (NCT05797792) | Hospital Clinic of Barcelona | 2023-11-18 |
| A Phase 3b Randomized, Double-blind, Multi-center Study to Compare the Safety and Efficacy of Omadacycline to Moxifloxacin for Treating Adult Subjects With CABP (NCT06162286) | Zai Lab (Hong Kong), Ltd. | 2023-11-17 |
| Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC (NCT06123754) | 3D Medicines (Sichuan) Co., Ltd. | 2023-11-17 |
| OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer (NCT06016738) | Olema Pharmaceuticals, Inc. | 2023-11-16 |
| A Study to Evaluate the Efficacy and Safety of SHR-1703 in Subjects With Eosinophilic Granulomatosis With Polyangiitis （EGPA） (NCT05979051) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2023-11-16 |
| A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) (NCT05920356) | Amgen | 2023-11-16 |
| A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer (NCT06144164) | Memorial Sloan Kettering Cancer Center | 2023-11-16 |
| A Study of the Efficacy and Safety of Antiwei Granules in the Treatment of Common Cold (NCT06697886) | Tasly Pharmaceutical Group Co., Ltd | 2023-11-16 |
| Chiglitazar/Metformin in Non-obese Women With PCOS (NCT06125587) | Shengjing Hospital | 2023-11-15 |
| Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension. (NCT06042478) | Novartis Pharmaceuticals | 2023-11-15 |
| The Impact Of SGLT2 -I on Metabolic Dysfunction -Associated Steatotic Liver Disease In Patients With Type 2 Diabetes Mellitus (NCT06117137) | Sohag University | 2023-11-15 |
| Safety and Immunogenicity of a Booster Vaccination With an Adapted Vaccine (NCT06181292) | Hipra Scientific, S.L.U | 2023-11-15 |
| Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC) (NCT06095583) | Shanghai Junshi Bioscience Co., Ltd. | 2023-11-15 |
| A Phase 3 Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDs (NCT06020144) | Hangzhou Highlightll Pharmaceutical Co., Ltd | 2023-11-15 |
| Oral Branched-chain Amino Acid Supplementation for Cirrhotic Patients With Sarcopenia (NCT06121492) | Mahidol University | 2023-11-15 |
| A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease (NCT06106828) | Hoffmann-La Roche | 2023-11-15 |
| A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease. (NCT06063967) | AbbVie | 2023-11-15 |
| Study of LAU-7b for the Treatment of Long COVID in Adults (NCT05999435) | Laurent Pharmaceuticals Inc. | 2023-11-15 |
| Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa (NCT05285917) | Brown University | 2023-11-15 |
| CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine (NCT06158698) | Niguarda Hospital | 2023-11-14 |
| CompariSon Between the EuroPeAn and Japanese pathologiCal InvEstigation for Colon Cancer (SPACE) (NCT06119867) | Russian Society of Colorectal Surgeons | 2023-11-14 |
| A Trial to Learn if Odronextamab Combined With Chemotherapy is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Chemotherapy for Adult Participants With Follicular Lymphoma (NCT06097364) | Regeneron Pharmaceuticals | 2023-11-14 |
| A Study of AK104/Tislelizumab With Chemotherapy as First-line Treatment in PD-L1 TPS < 1% Non-small Cell Lung Cancer (NCT05990127) | Akeso | 2023-11-14 |
| ACP-204 in Adults With Alzheimer's Disease Psychosis (NCT06159673) | ACADIA Pharmaceuticals Inc. | 2023-11-14 |
| A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer (NCT06112379) | AstraZeneca | 2023-11-14 |
| SAFE Nerve Sparing Guided by Micro-ultrasound (MUS) (NCT06945315) | Icahn School of Medicine at Mount Sinai | 2023-11-14 |
| An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM (NCT06116968) | Corxel Pharmaceuticals | 2023-11-14 |
| A Study of Efficacy and Safety of Hemay005 Tablets in Patients With Behçet's Disease (NCT06145893) | Ganzhou Hemay Pharmaceutical Co., Ltd | 2023-11-13 |
| Oral Branched-chain Amino Acid Supplementation for Decompensated Cirrhotic Patients (NCT06121479) | Mahidol University | 2023-11-13 |
| Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin (NCT06353347) | Shenzhen HighTide Biopharmaceutical Ltd. | 2023-11-13 |
| A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT) (NCT05319353) | Takeda | 2023-11-13 |
| Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004) (NCT06074588) | Merck Sharp & Dohme LLC | 2023-11-12 |
| Effect of Green Tea on Obese Pediatrics With Prediabetes (NCT06229795) | Ain Shams University | 2023-11-12 |
| Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL) (NCT06073821) | BeOne Medicines | 2023-11-11 |
| Esketamine Combined With Pregabalin on CPSP in Spinal Patients. (NCT06117917) | Beijing Tiantan Hospital | 2023-11-10 |
| Strong Albumin Solutions in Patients With Septic Shock (NCT05208242) | Manchester University NHS Foundation Trust | 2023-11-10 |
| A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (NCT06161571) | Akero Therapeutics, Inc | 2023-11-10 |
| Hysteroscopic Tubal Occlusion Using Amacrylate With or Without Lipidol in Patients With Hydrosalpinx Prior to IVF (NCT06130072) | Ain Shams University | 2023-11-10 |
| A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor (NCT06109311) | Eli Lilly and Company | 2023-11-10 |
| Extension Study to Evaluate Safety and Efficacy of Jaktinib in Patients With Active Ankylosing Spondylitis(AS) (NCT05861128) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2023-11-10 |
| High Versus Low Dose Nitroglycerin in Acute Pulmonary Edema (NCT06107465) | Alexandria University | 2023-11-10 |
| A Study to Evaluate the Efficacy and Safety of Infigratinib in Children and Adolescents With Achondroplasia (NCT06164951) | QED Therapeutics, a BridgeBio company | 2023-11-10 |
| Study to Assess the Safety and Effectiveness of NMRA-335140-501 (NCT06029439) | Neumora Therapeutics, Inc. | 2023-11-10 |
| Efficacy and Safety of AJU-S56 5% in Dry Eye Syndrome Patients (NCT06291194) | AJU Pharm Co., Ltd. | 2023-11-10 |
| Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome (NCT05726916) | Assistance Publique - Hôpitaux de Paris | 2023-11-09 |
| Impact of Annual Versus Biannual Infusions of Ocrelizumab in Patients With Active MS,After 2 Years of Initial Treatment, on Freedom From Radiological Disease Activity at Two Years: a Multicenter Randomized Controlled Non-inferiority Trial (NCT05999604) | Fondation Ophtalmologique Adolphe de Rothschild | 2023-11-09 |
| MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma (NCT06097728) | AstraZeneca | 2023-11-09 |
| Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression (NCT06112990) | University of Utah | 2023-11-09 |
| Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD (NCT05904028) | Jaeb Center for Health Research | 2023-11-09 |
| Efficacy and Safety of Tirofiban for Patients With BAD (BRANT) (NCT06037889) | Peking Union Medical College Hospital | 2023-11-09 |
| Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia. (NCT06023706) | Nantes University Hospital | 2023-11-08 |
| The Effect of Low Doses of Prednisone on the Prolongation of Pregnancy in Threatened Preterm Birth (NCT06103227) | University of Mostar | 2023-11-08 |
| A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy (NCT05924438) | Professor Francois Venter | 2023-11-08 |
| A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2 (NCT06072183) | Pfizer | 2023-11-08 |
| Metastasis-directed Therapy for Oligometastases of Breast Cancer (NCT06135714) | Tokyo Medical and Dental University | 2023-11-08 |
| Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) (NCT05925803) | AstraZeneca | 2023-11-08 |
| A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (NCT06130566) | Sanofi | 2023-11-08 |
| Fixed Dose Combination of COdeine + DIpyrone to Mitigate Moderate to Intense Pain Post-impacted Third Lower Molar Extraction (NCT04972292) | Eurofarma Laboratorios S.A. | 2023-11-08 |
| CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrence (NCT06037980) | Gruppo Oncologico del Nord-Ovest | 2023-11-07 |
| Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria) (NCT06087835) | AstraZeneca | 2023-11-07 |
| Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies (NCT05385432) | University Hospital, Tours | 2023-11-07 |
| Empagliflozin to Prevent Post-Operative Atrial Fibrillation (NCT06124937) | Rajaie Cardiovascular Medical and Research Center | 2023-11-07 |
| A Study to Evaluate Efficacy and Safety of Qingzhu Granules in the Treatment of Acute Gouty Arthritis (NCT06068478) | Tasly Pharmaceutical Group Co., Ltd | 2023-11-07 |
| Effect of TXA Oral Sol 5% in Patients Treated With DOACs or VKA and Undergoing a Single or Multiple Tooth Extraction (NCT06143787) | Hyloris Developments | 2023-11-07 |
| Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis. (NCT05782907) | AbbVie | 2023-11-06 |
| A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period (NCT06108544) | Takeda | 2023-11-06 |
| A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment (NCT06088043) | Takeda | 2023-11-06 |
| Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy (NCT05615844) | University of Maryland, Baltimore | 2023-11-05 |
| Montelukast in Parkinson Disease (NCT06113640) | Mostafa Bahaa | 2023-11-05 |
| Effect of Lidocaine in Reducing Opioids Requirement in Day Care Surgery (NCT06717672) | Liaquat National Hospital & Medical College | 2023-11-05 |
| The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency (NCT06046820) | Inozyme Pharma | 2023-11-05 |
| Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes (NCT06350890) | Shenzhen HighTide Biopharmaceutical Ltd. | 2023-11-05 |
| Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events (NCT06122948) | Kasr El Aini Hospital | 2023-11-04 |
| The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older (NCT06015282) | Seqirus | 2023-11-03 |
| Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome (NCT05819853) | University of Colorado, Denver | 2023-11-03 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy (NCT06071988) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain (NCT06071962) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET) (NCT06087276) | Praxis Precision Medicines | 2023-11-02 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy (NCT06072573) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis (NCT06071949) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain (NCT06072560) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy (NCT06071936) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis (NCT06072001) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy (NCT06071975) | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Comparing Tunlametinib Capsules and Combination Chemotherapy in Advanced NRAS-mutant Melanoma (NCT06008106) | Shanghai Kechow Pharma, Inc. | 2023-11-02 |
| A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma (NCT06054555) | Amgen | 2023-11-02 |
| Acceptability and Feasibility of Injectable Cabotegravir Pre-exposure Prophylaxis (PrEP) Versus Oral PrEP in Routine Care up to 15 Months in Private Pharmacies in South Africa (NCT06138600) | University of Witwatersrand, South Africa | 2023-11-01 |
| THE EFFECT OF VITAMIN C ON POST-ORTHODONTIC TREATMENT RELAPSE (NCT06146296) | Nourhan M.Aly | 2023-11-01 |
| The Effect of Mannitol Volume With Changes in Osmolarity in Traumatic Brain Injury (NCT06846307) | Universitas Diponegoro | 2023-11-01 |
| Aspirin Discontinuation in High-Risk Pregnant Women of Preeclampsia (NCT06111079) | FANG HE | 2023-11-01 |
| Effect of Short-term Basal Insulin Initiation in Newly Diagnosed Type 2 Diabetes on 1-year Glycemic Control (NCT06107153) | University of Basrah | 2023-11-01 |
| Silodosin vs Placebo in the Treatment of Female LUTS (NCT06114979) | Mansoura University | 2023-11-01 |
| Lapelga vs Gastrofil (NCT06116734) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2023-11-01 |
| Phase III Trial to Investigate Efficacy and Safety of Vilobelimab in Ulcerative Pyoderma Gangrenosum (NCT05964413) | InflaRx GmbH | 2023-11-01 |