| A Study to Evaluate the Efficacy and Safety of Tirbanibulin Ointment in Adult Participants With Actinic Keratosis (NCT06135415) | Almirall, S.A. | 2023-12-21 |
| Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder (NCT06058039) | Neumora Therapeutics, Inc. | 2023-12-21 |
| A Study of the Efficacy and Safety of Monotherapy With BCD-264 and Darzalex in Subjects With Relapsed and Refractory Multiple Myeloma (NCT06296121) | Biocad | 2023-12-21 |
| Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy (NCT06056830) | Clarity Pharmaceuticals Ltd | 2023-12-21 |
| A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3) (NCT06140836) | Bristol-Myers Squibb | 2023-12-21 |
| Extension Study in Primary Distal Renal Tubular Acidosis (NCT03831152) | Advicenne Pharma | 2023-12-20 |
| Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia (NCT06083948) | University of Aarhus | 2023-12-20 |
| Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma (NCT05948475) | TransThera Sciences (Nanjing), Inc. | 2023-12-20 |
| Global Trial in APG2575 for Patients With CLL/SLL (NCT06104566) | Ascentage Pharma Group Inc. | 2023-12-20 |
| Optimizing Early Nutrition Support in Severe Stroke-2 (NCT05998902) | Wen Jiang-3 | 2023-12-20 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Combined Modified RNA Vaccine Candidate Against COVID-19 and Influenza. (NCT06178991) | BioNTech SE | 2023-12-20 |
| Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder (NCT06058013) | Neumora Therapeutics, Inc. | 2023-12-20 |
| A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia (NCT05883956) | Otsuka Australia Pharmaceutical Pty Ltd | 2023-12-20 |
| Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients (NCT06165679) | Cairo University | 2023-12-20 |
| RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy (NCT06154252) | Cabaletta Bio | 2023-12-20 |
| MgSO4 as Adjuvants to Bupivacaine vs Neostigmine in TAP Block in Cesarean Section (NCT06513013) | Assiut University | 2023-12-20 |
| A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN) (NCT05912517) | Janssen Research & Development, LLC | 2023-12-20 |
| PARa-aOrtic LymphAdenectomy in Locally Advanced Cervical Cancer (NCT05581121) | Institut Claudius Regaud | 2023-12-20 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Safety and Efficacy of SAL003 in Combination With Statin Therapy in Patients With Hypercholesterolemia and Mixed Dyslipidemia (NCT07253584) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2023-12-19 |
| Efficacy and Safety of Orelabrutinib Combined With Rituximab Versus Lenalidomide Combined With Rituximab in Patients With Relapsed/Refractory Marginal Zone Lymphoma (NCT06082102) | Beijing InnoCare Pharma Tech Co., Ltd. | 2023-12-19 |
| A Study To Assess Adverse Events and Effectiveness of Upadacitinib Oral Tablets in Adult and Adolescent Participants With Vitiligo (NCT06118411) | AbbVie | 2023-12-19 |
| A Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of Booster Vaccination With Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell) (NCT06175494) | WestVac Biopharma Co., Ltd. | 2023-12-19 |
| Anxiolysis for Laceration Repair in Children (NCT05383495) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2023-12-19 |
| Metastasis-directed Therapy in Oligoprogressive Castration-refractory Prostate Cancer (NCT06585007) | Universitaire Ziekenhuizen KU Leuven | 2023-12-19 |
| UCMSCs as Treatment for Patients With Acute Ischemic Stroke (Stroke Neuroncell-EX) (NCT06129175) | Cytopeutics Sdn. Bhd. | 2023-12-19 |
| Comparison of Sequential CFA vs CFA +rFSH for Elective Fertility Preservation. (NCT06134479) | Fundación Santiago Dexeus Font | 2023-12-18 |
| A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Opthalmic Suspension Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery (NCT06128369) | Oculis | 2023-12-18 |
| Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases (NCT06173401) | Stanford University | 2023-12-18 |
| Enhancing Successful Return to Work of Employees With Cancer, by Supporting Employers (MiLES Intervention) (NCT06672887) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2023-12-18 |
| REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors) (NCT05973773) | Taiho Oncology, Inc. | 2023-12-18 |
| Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder (NCT05637879) | White River Junction Veterans Affairs Medical Center | 2023-12-18 |
| A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004) (NCT06136650) | Merck Sharp & Dohme LLC | 2023-12-18 |
| The Efficacy and Safety of Protoxin in Subjects With Moderate to Severe Glabellar Lines (NCT06124794) | Protox Inc. | 2023-12-18 |
| DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers (NCT05770037) | Cancer Research UK | 2023-12-18 |
| Romiplostim in Chemotherapy-Induced Thrombocytopenia (NCT06201663) | Ain Shams University | 2023-12-17 |
| Efficacy/Effectiveness, Safety, and Immunogenicity of LC16m8 Mpox Vaccine in Colombia (NCT06223919) | Universidad Nacional de Colombia | 2023-12-16 |
| Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) (NCT05512364) | European Organisation for Research and Treatment of Cancer - EORTC | 2023-12-15 |
| Evaluate the Efficacy and Safety of "Formosa 1-Breath Free (NRICM101) " in Subjects With the Symptoms of COVID-19 or Influenza-like Disease (NCT06175468) | China Medical University Hospital | 2023-12-15 |
| Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007) (NCT06170788) | Merck Sharp & Dohme LLC | 2023-12-15 |
| The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal Incontinence (NCT06166615) | Seoul National University Hospital | 2023-12-15 |
| Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis (NCT05796401) | Centre Hospitalier St Anne | 2023-12-15 |
| Effects of Letrozole During the Luteal Phase After Controlled Ovarian Stimulation in Oocyte Donors. (NCT06244745) | IVI Madrid | 2023-12-15 |
| Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity (NCT06140108) | SINA Health Education and Welfare Trust | 2023-12-15 |
| A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy (NCT06129864) | AstraZeneca | 2023-12-14 |
| Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults (NCT06139393) | Jiangsu HengRui Medicine Co., Ltd. | 2023-12-14 |
| TGRX-326 Chinese Phase III for Advanced Non-small Cell Lung Cancer (NSCLC) (NCT06082635) | Shenzhen TargetRx Co., Ltd. | 2023-12-14 |
| A Study of Adjuvant Cretostimogene Grenadenorepvec for Treatment of Intermediate Risk NMIBC Following TURBT (NCT06111235) | CG Oncology, Inc. | 2023-12-14 |
| Vitamin D for Prostate Endocrine Therapy (NCT05838716) | University of Rochester | 2023-12-14 |
| Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer (NCT05946213) | NRG Oncology | 2023-12-14 |
| Comparison Between Local Radiotherapy Alone or Combined With Obinutuzumab in Early Stage Follicular Lymphoma: the GAZEBO Trial From the Fondazione Italiana Linfomi (NCT05929222) | Fondazione Italiana Linfomi - ETS | 2023-12-14 |
| Goat or Cow Milk Based Infant Formula GMS (NCT06312059) | Kendal Nutricare Ltd | 2023-12-14 |
| MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) (NCT06128629) | Intellia Therapeutics | 2023-12-13 |
| Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis (NCT06141473) | Sanofi | 2023-12-13 |
| A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib (NCT05734105) | Deciphera Pharmaceuticals, LLC | 2023-12-13 |
| Brightline-4: A Study to Test How Well Brigimadlin is Tolerated by People With a Type of Cancer Called Dedifferentiated Liposarcoma (NCT06058793) | Boehringer Ingelheim | 2023-12-13 |
| Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers (NCT06282588) | Cancer Research Antwerp | 2023-12-13 |
| A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma (NCT06091865) | Regeneron Pharmaceuticals | 2023-12-13 |
| BAT1308 Combined with Platinum-Based Chemotherapy± Bevacizumab for PDL1-Positive (CPS ≥1) Cervical Cancer (NCT06123884) | Bio-Thera Solutions | 2023-12-13 |
| A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011) (NCT06136559) | Merck Sharp & Dohme LLC | 2023-12-13 |
| A Study of LNK01001 Capsule in Subjects With Active Rheumatoid Arthritis (COURAGE-RA) (NCT06276998) | Lynk Pharmaceuticals Co., Ltd | 2023-12-12 |
| Efficacy of Vitex Agnus-castus BNO 1095 (20 mg) in Women With Primary Dysmenorrhea (NCT06211049) | Bionorica SE | 2023-12-12 |
| A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma (NCT06091254) | Regeneron Pharmaceuticals | 2023-12-12 |
| An Efficacy and Safety Study of GNR-086 (Canakinumab Biosimilar) and Ilaris® in Patients With Adult-onset Still's Disease (NCT06497491) | AO GENERIUM | 2023-12-12 |
| Azathioprine in MOGAD (NCT05349006) | Hospices Civils de Lyon | 2023-12-12 |
| A Phase III Clinical Study to Compare the Safety and Efficacy of 177Lu-DOTATATE Injection and Long-acting Oxytrexine in Adult Patients With NETs (NCT07057622) | HTA Co., Ltd. | 2023-12-12 |
| A Study to Assess the Adverse Events and Effectiveness of BOTOX Injections for the Treatment of Moderate to Severe Forehead Lines in Chinese Adult Participants (NCT06174688) | AbbVie | 2023-12-12 |
| Study Comparing RT With Cetuximab + Xevinapant to RT With Cetuximab-placebo in Patients With Head and Neck Cancer (NCT05930938) | Groupe Oncologie Radiotherapie Tete et Cou | 2023-12-12 |
| Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution (NCT05938699) | Nicox Ophthalmics, Inc. | 2023-12-12 |
| Contribution of PET (Positron Emission Tomography) Scans for the Preoperative Assessment of Symptomatic Endometriosis Lesions: TEP-ENDORUN (NCT04831619) | Centre Hospitalier Universitaire de la Réunion | 2023-12-12 |
| Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor (NCT05834777) | Vanderbilt University Medical Center | 2023-12-11 |
| INcreased Sun Exposure Without Pain In Research Participants With EPP or XLP (NCT06144840) | Tanabe Pharma America, Inc. | 2023-12-11 |
| A Study to Investigate the Efficacy and Safety of OTL-203 in Subjects With MPS-IH Compared With Standard of Care With Allogeneic HSCT (NCT06149403) | Orchard Therapeutics | 2023-12-11 |
| A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease (NCT05995353) | AbbVie | 2023-12-11 |
| Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucoma (NCT05710198) | Omikron Italia S.r.l. | 2023-12-11 |
| Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity (NCT06067958) | Assaf-Harofeh Medical Center | 2023-12-11 |
| Intermittent Darolutamide Treatment in the Triple Therapy of mHSPC (NCT06177015) | The First Affiliated Hospital with Nanjing Medical University | 2023-12-11 |
| A Study to Evaluate the Safety and Efficacy of HL231 Solution for Inhalation in Patients With COPD (NCT06643078) | Haisco Pharmaceutical Group Co., Ltd. | 2023-12-11 |
| A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer) (NCT06065748) | Hoffmann-La Roche | 2023-12-11 |
| Compare the Perioperative Analgesic Effect of Ultrasound Guided Thoracic Paravertebral Block and Ultrasound Guided Serratus Anterior Block in Patients Undergoing Thoracotomy (NCT06831578) | Menoufia University | 2023-12-10 |
| IMMUNERECOV CONTRIBUTES TO IMPROVEMENT OF RESPIRATORY AND IMMUNOLOGICAL RESPONSE IN POST-COVID-19 PATIENTS. (NCT06166030) | Federal University of São Paulo | 2023-12-10 |
| Randomized Clinical Trial of Two Different Initial Growth Hormone Doses in Children (NCT06103513) | Northwell Health | 2023-12-10 |
| DMT310-009 Topical in the Treatment of Acne Vulgaris (NCT06090721) | Dermata Therapeutics | 2023-12-08 |
| Evaluation of the Efficacy of Therapeutic Infiltrations of the Pudendal Nerve, Performed Under Neurostimulation on Pain, 1 Month After an Infiltration of Local Anaesthetic, in the Treatment of Pudendal Neuralgia. (NCT06872437) | Groupe Hospitalier Diaconesses Croix Saint-Simon | 2023-12-08 |
| A Study to Learn About the Study Medicine Sisunatovir in Adults With Respiratory Syncytial Virus (RSV) Infection (NCT06079320) | Pfizer | 2023-12-08 |
| Early Initiated Vasopressor Therapy in the Emergency Department (NCT05931601) | Odense University Hospital | 2023-12-08 |
| Continuation Study for Latozinemab (NCT06111014) | Alector Inc. | 2023-12-08 |
| A Phase 3 Study of AGA111 in Patients With Degenerative Disc Disease Undergoing Lumbar Interbody Fusion (NCT06115512) | Angitia Biopharmaceuticals | 2023-12-08 |
| A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines (NCT05976243) | Novartis Pharmaceuticals | 2023-12-07 |
| Economic Evaluation of Stream™ Platform (NCT05994625) | FluidAI Medical | 2023-12-06 |
| BE Study of Albuterol Sulfate Inhalation Aerosol 90 mcg Per Actuation in Patients With Stable Mild Asthma (NCT06154304) | Cipla Ltd. | 2023-12-06 |
| Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005) (NCT06132958) | Merck Sharp & Dohme LLC | 2023-12-06 |
| Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study. (NCT05333523) | Radboud University Medical Center | 2023-12-06 |
| A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma (NCT06007690) | Aura Biosciences | 2023-12-06 |
| A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002) (NCT06077760) | Merck Sharp & Dohme LLC | 2023-12-06 |
| A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction (NCT05887271) | University of Leicester | 2023-12-05 |
| Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer. (NCT06072612) | BriaCell Therapeutics Corporation | 2023-12-05 |
| Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement (NCT06489431) | Rush University Medical Center | 2023-12-04 |
| Efficacy and Safety of XC8, Film-coated Tablets, in Children With Acute Respiratory Viral Infections (NCT06379542) | Valenta Pharm JSC | 2023-12-04 |
| Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents (NCT03516968) | Hospices Civils de Lyon | 2023-12-04 |
| Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01) (NCT06109779) | AstraZeneca | 2023-12-04 |