| A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight (NCT06388187) | Novo Nordisk A/S | 2024-06-24 |
| SIM0718 Treatment of Asthma Clinical Study (NCT06488755) | Simcere Pharmaceutical Co., Ltd | 2024-06-23 |
| Evaluation of the Therapeutic Effects of Curcumin on Changes in Lipid, Metabolic, and Hormonal Profiles, Liver Enzyme Activity, and Ultrasonography Morphology of the Liver in Women With Polycystic Ovary Syndrome and Nonalcoholic Fatty Liver Disease: A Double-blind, Placebo-controlled Clinical Trial (NCT07278128) | Fateme Moshirenia | 2024-06-22 |
| A 3- to 5-day Clinical Trial of Levamisole in Loiasis Infected Subjects (NCT06252961) | Programme National de Lutte contre l'Onchocercose, Republic of the Congo | 2024-06-21 |
| A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer(PANKU-Breast02) (NCT06382142) | Sichuan Baili Pharmaceutical Co., Ltd. | 2024-06-21 |
| Efficacy of Diacerein Supplementation on Interleukin-1β, Hs-CRP, TNF-α Levels and Glycemic Control in Uncontrolled Type 2 Diabetes Mellitus Patients at Dr. Mohammad Hoesin General Hospital Palembang (NCT06912035) | Universitas Sriwijaya | 2024-06-21 |
| Oto Smartphone App in Treating Tinnitus Amongst Adult Patients Compared with Standard Talking Therapies (NCT06623123) | East and North Hertfordshire NHS Trust | 2024-06-20 |
| A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures (NCT06425159) | Biohaven Therapeutics Ltd. | 2024-06-20 |
| TYK2 Inhibition in Paradoxical Psoriasis (NCT06281106) | Prof Curdin Conrad | 2024-06-20 |
| Comparison of General Anesthesia Hemodynamics Between R and P in Patients Undergoing Laparoscopic Hepatectomy (NCT06714669) | Sun Yat-sen University | 2024-06-20 |
| A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis) (NCT06455449) | AstraZeneca | 2024-06-20 |
| To Evaluate HU-045 in the Treatment of Glabellar Lines(Phase III) (NCT06205797) | Huons Biopharma | 2024-06-20 |
| A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma (NCT06388733) | Ivy Brain Tumor Center | 2024-06-19 |
| A Study of AK104/Placebo Plus AK109/Placebo And Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma (NCT06341335) | Akeso | 2024-06-19 |
| Study of Lumateperone in the Acute Treatment of Patients With Bipolar Mania (NCT06462586) | Intra-Cellular Therapies, Inc. | 2024-06-19 |
| Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies (NCT07290491) | The Methodist Hospital Research Institute | 2024-06-19 |
| Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma (NCT06356129) | Celgene | 2024-06-19 |
| Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma (NCT06124976) | Peter Black | 2024-06-19 |
| Photodynamic Diagnosis for Malignant Brain Glioma With 5-Aminolevulinic Acid(5-ALA) (NCT06417281) | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | 2024-06-19 |
| Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic High-Potency Single Antiplatelet Therapy to Neutralize Bleeding Complications in Patients With High Bleeding Risk Beyond One Month After an Acute Coronary Syndrome (NCT05577988) | Assistance Publique - Hôpitaux de Paris | 2024-06-18 |
| To Compare Efficacy and Safety of CMAB007 and Xolair® in Patients With Chronic Spontaneous Urticaria (NCT06365879) | Taizhou Mabtech Pharmaceutical Co.,Ltd | 2024-06-18 |
| Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus (NCT06446310) | Qilu Pharmaceutical (Hainan) Co., Ltd. | 2024-06-18 |
| Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study) (NCT05935826) | University of Colorado, Denver | 2024-06-18 |
| A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa (NCT06388200) | Ocugen | 2024-06-18 |
| Interventional Study of Vosoritide for the Treatment of Children With Hypochondroplasia (NCT06455059) | BioMarin Pharmaceutical | 2024-06-17 |
| Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery (NCT06414031) | Ulrich Ronellenfitsch, MD | 2024-06-17 |
| TREAT-SC: Early, Short Course Oral Dexamethasone for the Treatment of Sydenham Chorea in Children (NCT06259006) | Starship Child Health, Te Toka Tumai Auckland | 2024-06-17 |
| A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma (NCT06471257) | AstraZeneca | 2024-06-17 |
| A Study of the Efficacy, Safety, and Pharmacokinetics (PK) of the Port Delivery System With Ranibizumab (PDS) in Chinese Participants With Neovascular Age-related Macular Degeneration (nAMD) (NCT05562947) | Hoffmann-La Roche | 2024-06-17 |
| A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure (NCT06424288) | Boehringer Ingelheim | 2024-06-17 |
| the Efficacy of Ginger Powder as an Analgesic for Intraoperative and Post- Endodontic Pain Management (NCT06439212) | Cairo University | 2024-06-15 |
| The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries. (NCT06427707) | Ain Shams University | 2024-06-15 |
| Probucol for Symptomatic Intracranial and Extracranial Artery Stenosis (NCT06225752) | First Affiliated Hospital of Wannan Medical College | 2024-06-15 |
| Transcutaneous Spinal Cord Stimulation for Upper Extremity Function (NCT06596369) | University of Alberta | 2024-06-15 |
| The Effectiveness and Safety of Two Low-concentration Atropine Sulfate Eye Drops (0.01%/0.02%) for Delaying the Pediatric Myopia Progression (NCT06708156) | Oupushifang Pharmaceutical Technology Co., Ltd. | 2024-06-15 |
| Assessment of the Efficacy of Scorpion Antivenom Therapy in a Dose-response Manner, in Patients With Scorpionism (NCT06333834) | Selene Guadalupe Huerta Olvera | 2024-06-15 |
| Preventing Celiac Disease by Weaning With Mediterranean Diet (NCT06184906) | University of Naples | 2024-06-15 |
| Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes (NCT06334133) | vTv Therapeutics | 2024-06-14 |
| A Study of Rozanolixizumab in Pediatric Study Participants With Moderate to Severe Generalized Myasthenia Gravis (NCT06149559) | UCB Biopharma SRL | 2024-06-14 |
| The Trial of SHR6508 in Secondary Hyperparathyroidism (NCT06434961) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2024-06-14 |
| A Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Patients (NCT06508983) | Hangzhou Sumgen Biotech Co., Ltd. | 2024-06-14 |
| Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis (NCT06468956) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2024-06-14 |
| A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab (NCT06389136) | AbbVie | 2024-06-14 |
| Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients Pilot Trial (NCT05841056) | Population Health Research Institute | 2024-06-13 |
| Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer (NCT06122584) | ABX advanced biochemical compounds GmbH | 2024-06-13 |
| APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia (NCT06408181) | University of Pennsylvania | 2024-06-12 |
| Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer (NCT06509126) | National Cancer Institute, Naples | 2024-06-12 |
| Phase III Long-Term Extension Study With Dexpramipexole (NCT06388889) | Areteia Therapeutics | 2024-06-12 |
| Dalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple Sclerosis (NCT06136728) | MGH Institute of Health Professions | 2024-06-12 |
| Randomized, Open, Controlled, Multicenter Phase III Clinical Study of Fluzoparib in Combination With Apatinib Versus Investigator-Selected Chemotherapy for HRD-Positive/HER2-negative Advanced Breast Cancer (NCT06255392) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2024-06-12 |
| Fluorizoparib Plus Apatinib Versus Chemotherapy in HRD-positive, HER2-negative Advanced Breast Cancer (NCT07371910) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2024-06-12 |
| Efficacy and Safety of Vaginal Lactobacillus Dual Probiotic Capsules in Bacterial Vaginosis (NCT07418957) | Guangdong Longchuangji Pharmaceutical Co., Ltd. | 2024-06-12 |
| Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009) (NCT06305754) | Merck Sharp & Dohme LLC | 2024-06-11 |
| A Clinical Study of Lutetium[177Lu] Oxodotreotide Injection in Patients With Advanced Neuroendocrine Neoplasms (NCT06398444) | Sinotau Pharmaceutical Group | 2024-06-11 |
| A Pivotal Study of APG-2575 (Lisaftoclax) Combined With Azacitidine in the Treatment of Acute Myeloid Leukemia (NCT06389292) | Ascentage Pharma Group Inc. | 2024-06-11 |
| Effect of Ensifentrine Treatment on CAT Score (NCT06460493) | Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA | 2024-06-11 |
| PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic TNBC (NCT06419621) | Biotheus Inc. | 2024-06-11 |
| A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer (NCT06320067) | University College, London | 2024-06-11 |
| A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC) (NCT06472076) | GlaxoSmithKline | 2024-06-10 |
| Prevalence of Asymptomatic H Pylori Infection Among Patients Undergoing PCI and Impact of Its Eradication on Occurrence of GIT Symptoms and Bleeding" (NCT07487142) | Beni-Suef University | 2024-06-10 |
| Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023] (NCT06422143) | Merck Sharp & Dohme LLC | 2024-06-10 |
| DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease (NCT06384573) | Washington University School of Medicine | 2024-06-10 |
| PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases (NCT06519266) | Vastra Gotaland Region | 2024-06-10 |
| Parasite Clearance and Protection From Infection (PCPI) in Cameroon (NCT06173206) | London School of Hygiene and Tropical Medicine | 2024-06-10 |
| A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis (NCT06311682) | LEO Pharma | 2024-06-10 |
| Efficacy and Safety of NestaCell® in Huntington's Disease (NCT06097780) | Azidus Brasil | 2024-06-08 |
| Study of Mosunetuzumab Plus Lenalidomide Compared to Anti-CD20 Anti-body + Chemotherapy in Follicular Lymphoma FLIPI2-5 (NCT06284122) | The Lymphoma Academic Research Organisation | 2024-06-07 |
| A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NCT06448312) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2024-06-07 |
| Study of Zanzalintinib (XL092) + Pembrolizumab vs Pembrolizumab in Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (NCT06082167) | Exelixis | 2024-06-07 |
| Wereables for Upper Limb Functionality in Hemiparesis (NCT06872736) | Universidade da Coruña | 2024-06-07 |
| Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery (NCT05695391) | Laboratoire français de Fractionnement et de Biotechnologies | 2024-06-07 |
| Personalising and Refining Neo-adjuvant Chemotherapy in Locally Advanced but Resecable Colon Cancer in the Elderly of 70 Years Old or More (NCT06293625) | Centre Hospitalier Universitaire Dijon | 2024-06-07 |
| Anti-Inflammatory Reliever South Africa (NCT06429475) | University of KwaZulu | 2024-06-06 |
| A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections (NCT06056297) | X4 Pharmaceuticals | 2024-06-06 |
| Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children (NCT06271174) | Nantes University Hospital | 2024-06-06 |
| A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP) (NCT06367972) | M.D. Anderson Cancer Center | 2024-06-06 |
| IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301) (NCT06112314) | Immunocore Ltd | 2024-06-05 |
| A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008) (NCT06430801) | Merck Sharp & Dohme LLC | 2024-06-05 |
| Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France. (NCT05813964) | ANRS, Emerging Infectious Diseases | 2024-06-05 |
| Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab (NCT06211036) | Amgen | 2024-06-05 |
| Croup Dosing Study (NCT06272383) | University of Manitoba | 2024-06-05 |
| Lebrikizumab Pen Ease of Use in Participants With Atopic Dermatitis (NCT06444165) | Eli Lilly and Company | 2024-06-04 |
| Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin (NCT06415773) | Shenzhen HighTide Biopharmaceutical Ltd. | 2024-06-04 |
| Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (NCT06336733) | Assistance Publique - Hôpitaux de Paris | 2024-06-04 |
| Efficacy and Safety of 0.01%, 0.03%, and 0.05% Atropine Eye Drops in Reducing Myopia Progression (NCT07626892) | Khyber Medical College, Peshawar | 2024-06-03 |
| A Trial to Compare Nebulized Amphotericin B and Nebulized Normal Saline as Maintenance in Patients With Chronic Pulmonary Aspergillosis (NCT06447402) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2024-06-03 |
| Metformin Treatment of Patients with Hand Osteoarthritis (NCT06367283) | Marius Henriksen | 2024-06-03 |
| Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib (NCT06479135) | Kartos Therapeutics, Inc. | 2024-06-03 |
| Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections (NCT06363877) | Loma Linda University | 2024-06-03 |
| A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2) (NCT06439277) | Eli Lilly and Company | 2024-06-03 |
| Postbiotic as Adjunct Treatment for Vaginal Candidiasis (NCT06474247) | Min-Tze LIONG | 2024-06-02 |
| The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis (NCT06470386) | Shanghai Changzheng Hospital | 2024-06-01 |
| Sugammadex Vs Neostigmine in Reversing Neuromuscular Blocks in Outpatient ERCP. A Randomized, Double-Blinded Trial (NCT06136585) | The Cleveland Clinic | 2024-06-01 |
| Prolonged Hypercoagulability Following Major Liver Resection for Malignancy (NCT06153394) | Western University, Canada | 2024-06-01 |
| Enteral Zinc Supplementation in Very Low Birth Weight Infants (NCT06433674) | University of Tennessee | 2024-06-01 |
| Effectiveness of Different THR Products in Adult Population (NCT05825924) | Foundation for a Smoke Free World INC | 2024-06-01 |
| SAVES-IBD: Safety & Efficacy of Aspirin vs. Standard of Care for VTE Prophylaxis After IBD Surgery (NCT05104229) | Stefan Holubar MD MS FACS, FASCRS | 2024-06-01 |
| Single-Arm Study Evaluating Use of the CORA Catheters for the Crossing of Coronary Chronic Total Occlusions (NCT05848232) | ReFlow Medical, Inc. | 2024-06-01 |
| Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults (NCT06414837) | Jiangsu HengRui Medicine Co., Ltd. | 2024-06-01 |
| Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block (NCT06386770) | Aswan University | 2024-06-01 |