| A Study to Investigate Stannous Fluoride Containing Toothpaste on Antibacterial Effects in the Different Regions of the Mouth (NCT07458464) | Colgate Palmolive | 2026-08-01 |
| A Study Comparing BL-M07D1 With Physician's Choice Therapy in Patients With HER2 IHC3+ Advanced Colorectal Cancer Who Failed Prior Treatment With Oxaliplatin, Fluorouracil and Irinotecan (NCT07730489) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-08-01 |
| A Study of BL-B01D1 Plus an Anti-PD-1 Antibody Versus Nab-paclitaxel Plus an Anti-PD-1 Antibody in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Express PD-L1 (PANKU-Breast04) (NCT07729956) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-08-01 |
| Lumateperone for Late-Life Depression (NCT07623135) | Eric Lenze | 2026-08-01 |
| A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes (NCT07743450) | Ascletis Pharma (China) Co., Limited | 2026-08-01 |
| Stibium Metallicum Praeparatum 6x Versus Placebo in the Prevention of Paclitaxel-induced Peripheral Neurotoxicity (NCT04715542) | University of Bern | 2026-08-01 |
| A Phase 3 Study of Rezpegaldesleukin (NKTR-358) for Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis (NCT07711418) | Nektar Therapeutics | 2026-08-01 |
| CiLostAzol for pReventIon of Recurrent sTroke in Africa (NCT06919835) | Northern California Institute of Research and Education | 2026-08-01 |
| A Phase III Study of KHN939 in Chinese Patients With Moderate-to-Severe Active Thyroid Eye Disease (NCT07720635) | Beijing Kanghong Biological Medicine Co., Ltd. | 2026-08-01 |
| Progesterone Luteal Support in Unexplained Infertility Management (NCT07738068) | Simone Broer | 2026-08-01 |
| Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder (NCT06807918) | University of Pennsylvania | 2026-08-01 |
| A Study Comparing BL-B01D1 in Combination With PD-1/VEGF Bispecific Antibody Versus Chemotherapy in Combination With PD-1/VEGF Bispecific Antibody in First-line Patients With Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer(PANKU-Lung05) (NCT07739199) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-08-01 |
| A Phase 3 Trial of DR10624 Versus Placebo in Patients With Severe Hypertriglyceridemia (NCT07680829) | Zhejiang Doer Biologics Co., Ltd. | 2026-08-01 |
| Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia (NCT07473843) | Arrowhead Pharmaceuticals | 2026-08-01 |
| Efficacy and Safety of Utidelone Capsule and Utidelone Injection in Patients With HER-2 Negative Advanced Breast Cancer (NCT07684456) | Beijing Biostar Pharmaceuticals Co., Ltd. | 2026-08-01 |
| A Study Evaluating BL-B01D1 in Combination With a PD-1/VEGF Bispecific Antibody Versus Tislelizumab Plus Platinum-doublet Chemotherapy as First-line Treatment for Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer(PANKU-Lung06) (NCT07739186) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-08-01 |
| A Study to Investigate the Efficacy and Safety of Letrozole SIE Compared With Femara® (Both Combined With the CDK4/6 Inhibitor Ribociclib) in Postmenopausal Women With HR-Positive, HER2-Negative, Inoperable Locally Advanced or Metastatic Breast Cancer (NCT07340658) | Rovi Pharmaceuticals Laboratories | 2026-08-01 |
| Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya (NCT06790342) | University of Chicago | 2026-07-31 |
| IBI363 Combined With Bevacizumab for Advanced Colorectal Cancer (NCT07722494) | Innovent Biologics (Suzhou) Co. Ltd. | 2026-07-31 |
| Additional Phase 3 Study of KP-100IT in Subjects With Acute Spinal Cord Injury (NCT07722962) | Kringle Pharma, Inc. | 2026-07-31 |
| Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or Without Ipilimumab N01 in Resectable Gastric/Gastroesophageal Junction Adenocarcinoma (NCT07643623) | Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. | 2026-07-31 |
| Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin (NCT07441681) | NRG Oncology | 2026-07-31 |
| A Study of Econoglutide Injection in Obese Participants With Knee Osteoarthritis (KOA) (NCT07734311) | Hangzhou Sciwind Biosciences Co., Ltd. | 2026-07-31 |
| A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and Pediatric Participants With Allergic Conjunctivitis Due to Cat Allergy (NCT07675811) | Regeneron Pharmaceuticals | 2026-07-31 |
| Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation (NCT07626411) | Regeneron Pharmaceuticals | 2026-07-31 |
| A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment of Patchy Hair Loss, Known by the Medical Term as Moderate Alopecia Areata (NCT07733765) | Pfizer | 2026-07-31 |
| A Study of Olezarsen for the Treatment of Familial Chylomicronemia Syndrome (FCS) in Pediatric Participants (NCT07727538) | Ionis Pharmaceuticals, Inc. | 2026-07-31 |
| A Study of HS-20093 in Patients With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (NCT07621601) | Hansoh BioMedical R&D Company | 2026-07-31 |
| Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study (NCT07620574) | Exelixis | 2026-07-30 |
| Efficacy and Safety of Ravulizumab in Chinese Adults Participants With Generalized Myasthenia Gravis (gMG) (NCT07596784) | Alexion Pharmaceuticals, Inc. | 2026-07-30 |
| QL1706 Plus Anlotinib as a Later-line Treatment for Patients With Advanced Lung Cancer (NCT07636226) | Sun Yat-sen University | 2026-07-30 |
| A Study to Investigate the Safety, Pharmacokinetics (PK), and Efficacy of Garetosmab in Children and Adolescents With Fibrodysplasia Ossificans Progressiva (FOP) (NCT07559513) | Regeneron Pharmaceuticals | 2026-07-30 |
| Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2) (NCT07653477) | The United Bio-Technology (Hengqin) Co., Ltd. | 2026-07-30 |
| TR115 VS Investigator's Choice in Relapsed/Refractory Peripheral T/NK Cell Lymphoma (NCT07639879) | Tarapeutics Science Inc. | 2026-07-30 |
| Mitoxantrone Hydrochloride Liposome, Cytarabine, G-CSF Plus Venetoclax vs. Azacitidine Plus Venetoclax for MDS-IB2 and Secondary/Elderly AML (NCT07735117) | Ruijin Hospital | 2026-07-30 |
| Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION) (NCT07684144) | Amgen | 2026-07-29 |
| A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic Migraine (NCT07729462) | Pfizer | 2026-07-29 |
| A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder (NCT07759128) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2026-07-28 |
| Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE) (NCT07218354) | VA Office of Research and Development | 2026-07-28 |
| A Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis (NCT07465289) | UCB Biopharma SRL | 2026-07-27 |
| Caffeine Consumption and Rate Control in Permanent Atrial FIBrillation: The CAFIB Trial (NCT07738523) | Hospital Universitario Getafe | 2026-07-27 |
| Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced Mucositis (NCT07736495) | Ain Shams University | 2026-07-27 |
| A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression (NCT07716098) | Janssen Research & Development, LLC | 2026-07-27 |
| A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis (NCT07497087) | Boehringer Ingelheim | 2026-07-27 |
| A Study to Evaluate GFH375 Versus Docetaxel in Participants With Non-Small Cell Lung Cancer With KRAS G12D Mutation (NCT07668752) | Genfleet Therapeutics (Shanghai) Inc. | 2026-07-27 |
| A Study to Evaluate 20vPnC in Healthy Chinese Infants (NCT07754539) | Pfizer | 2026-07-25 |
| Whole Versus Partial Gland Boost During Prostate SBRT (NCT07574489) | University of Nebraska | 2026-07-25 |
| Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies (NCT07648264) | CSL Behring | 2026-07-24 |
| Individualized Primary Clinical Target Volume Based on Margin Expansion for Nasopharyngeal Carcinoma (NCT07661771) | Sun Yat-sen University | 2026-07-24 |
| Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old (NCT07118800) | UNICANCER | 2026-07-24 |
| A Clinical Study to Evaluate the Efficacy and Safety of HRS9531 Tablets in Overweight or Obese Subjects (NCT07670884) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2026-07-24 |
| An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer's Disease (NCT07724132) | University College, London | 2026-07-24 |
| A Study of BL-B01D1 in Combination With Osimertinib as Perioperative Therapy in Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer(PANKU-Lung09) (NCT07642024) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-07-24 |
| Impact of Minimally Invasive Endodontic Treatment on the Prognosis of Mandibular Permanent Molars With Necrotic Pulp and Apical Periodontitis (NCT07762248) | Mohamed Ashraf Abdeen | 2026-07-23 |
| Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION) (NCT07684235) | Amgen | 2026-07-23 |
| A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH) (NCT07701993) | GlaxoSmithKline | 2026-07-22 |
| A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH) (NCT07704892) | GlaxoSmithKline | 2026-07-22 |
| A Continued Access Study for Participants Transitioning From ViiV Healthcare-sponsored or ViiV Healthcare-collaborative Parent Studies for HIV Treatment (NCT07393659) | ViiV Healthcare | 2026-07-21 |
| A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD) (NCT07656415) | Agios Pharmaceuticals, Inc. | 2026-07-21 |
| Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa (NCT07482787) | Paradigm Therapeutics | 2026-07-21 |
| A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD) (NCT07366034) | Boehringer Ingelheim | 2026-07-21 |
| Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients (NCT07721324) | Ain Shams University | 2026-07-21 |
| PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis (NCT07232069) | Duke University | 2026-07-21 |
| Study to Evaluate the Efficacy and Safety of Lerodalcibep in Children 6 to 17 Years, With Heterozygous FH (NCT07102511) | LIB Therapeutics LLC | 2026-07-20 |
| Efficacy and Safety of Becotatug Vedotin (MRG003) Combined With Anti-PD1 as Maintenance Therapy for Recurrent and Metastatic Nasopharyngeal Carcinoma (NCT07705243) | Sun Yat-sen University | 2026-07-20 |
| Efficacy and Safety of TPC Induction Chemotherapy Combined With Nimotuzumab and Toripalimab "Immune Sandwich" Regimen Versus Full-Course Immunotherapy for Locally Advanced Nasopharyngeal Carcinoma (NCT07706985) | Sun Yat-sen University | 2026-07-20 |
| Study of Secutrelvir in Participants With COVID-19 (NCT07746544) | Shionogi | 2026-07-20 |
| Personalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal Cancer Using a Blood Test (NCT07340567) | UNICANCER | 2026-07-20 |
| A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP) (NCT07700238) | Amgen | 2026-07-20 |
| An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) (NCT07234032) | Insmed Incorporated | 2026-07-20 |
| Evaluation of the Efficacy and Safety of Tirzepatide, a Dual GLP-1/GIP Agonist, on Functional Capacity in Reduced Ejection Fraction Heart Failure Patients With Obesity (NCT07738276) | Shahid Beheshti University of Medical Sciences | 2026-07-18 |
| A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) (NCT07654374) | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics | 2026-07-17 |
| Cognitive Strategies in Early Psychosis 2 (NCT07263022) | University of Minnesota | 2026-07-17 |
| Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of VG081821AC Tablets in Patients With Early to Mid-stage Parkinson's Disease (NCT07725562) | Zhejiang Vimgreen Pharmaceuticals, Ltd. | 2026-07-17 |
| A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05) (NCT07743164) | Merck Sharp & Dohme LLC | 2026-07-17 |
| Phase III Study of HRS-5635 in Nucleos(t)Ide Analogue-suppressed HBeAg-negative Patients With Chronic Hepatitis B (NCT07606950) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2026-07-17 |
| Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden (NCT07621809) | Novartis Pharmaceuticals | 2026-07-16 |
| An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC (NCT07720284) | AstraZeneca | 2026-07-16 |
| the Effect of Ginkgo Biloba on Rheumatoid Arthritis Patients (NCT07709312) | Ain Shams University | 2026-07-15 |
| Yang et al. Anti-PD-1/CTLA-4 Dual Immunotherapy for LARC (NCT07596290) | Beijing Friendship Hospital | 2026-07-15 |
| An Open Label Extension Safety Study to Evaluate SD-101 in Epidermolysis Bullosa (NCT07482813) | Paradigm Therapeutics | 2026-07-15 |
| A Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the Combination of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID (NCT06974084) | HealthBio, Inc. | 2026-07-15 |
| A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS) (NCT07466316) | Children's Oncology Group | 2026-07-14 |
| Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation (NCT07688551) | University of South Carolina | 2026-07-14 |
| Study of Lenacapavir, Teropavimab, and Zinlirvimab in Virologically Suppressed Adults With HIV-1 on Stable Oral Treatment Regimens (NCT07683000) | Gilead Sciences | 2026-07-14 |
| Precision Management of Urinary Tract Symptoms in Older Women (NCT07686055) | Megan Bradley | 2026-07-14 |
| A Phase 3 Study of Fenfluramine Hydrochloride in Rett Syndrome (NCT07503444) | UCB BIOSCIENCES, Inc. | 2026-07-14 |
| Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral Therapy (NCT07682961) | Gilead Sciences | 2026-07-14 |
| A Study of Intravesical SHR-1501 Combination With BCG Versus Investigator-selected Chemotherapy in Subjects With BCG-unresponsive NMIBC (NCT07424287) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-07-13 |
| Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) (NCT07654361) | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics | 2026-07-13 |
| A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of HSK39004 Inhalation Suspension in Patients With COPD (NCT07658339) | Haisco Pharmaceutical Group Co., Ltd. | 2026-07-11 |
| Study Comparing Two Serums With Intense Pulsed Light for the Treatment of Moderate to Severe Photodamage and Crepiness on the Forearms (NCT07686198) | Goldman, Butterwick, Fitzpatrick and Groff | 2026-07-10 |
| An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS (NCT07665437) | Novartis Pharmaceuticals | 2026-07-10 |
| DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy (NCT07544654) | Boehringer Ingelheim | 2026-07-10 |
| A Study of MI078 for Postpartum Depression (NCT07721961) | Nanjing Minova Pharmaceutical Co., Ltd. | 2026-07-10 |
| Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease (NCT07318610) | Regeneron Pharmaceuticals | 2026-07-10 |
| Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality (NCT07466953) | Mert Ersan | 2026-07-10 |
| Single-Dose vs. Divided-Dose G-CSF for Stem Cell Mobilization in Healthy Allogeneic Donors (NCT07692841) | First Affiliated Hospital of Zhejiang University | 2026-07-10 |
| A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline) (NCT07585266) | GlaxoSmithKline | 2026-07-10 |
| Long-Term Safety and Efficacy of HSK39004 Inhalation Suspension in COPD (NCT07634367) | Haisco Pharmaceutical Group Co., Ltd. | 2026-07-10 |