| Herpetic Eye Disease Study (HEDS) I (NCT00000138) | National Eye Institute (NEI) | 1989-05-01 |
| Randomized Boost Versus no Boost Irradiation of Early Breast Cancer (NCT02295033) | European Organisation for Research and Treatment of Cancer - EORTC | 1989-05-01 |
| Thrombolysis in Myocardial Ischemia Trial (TIMI III) (NCT00000472) | National Heart, Lung, and Blood Institute (NHLBI) | 1989-04-01 |
| Somatropin Treatment to Final Height in Turner Syndrome (NCT00191113) | Eli Lilly and Company | 1989-02-01 |
| The Modification of Diet in Renal Disease Study (NCT04364113) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 1989-01-01 |
| Infant Heart Surgery: Central Nervous System Sequelae of Circulatory Arrest (NCT00000470) | Boston Children's Hospital | 1988-12-01 |
| Iodine I-131 Iodocholesterol, Its Use in Adrenal Screening (NCT00037843) | M.D. Anderson Cancer Center | 1988-12-01 |
| Central Vein Occlusion Study (CVOS) (NCT00000131) | National Eye Institute (NEI) | 1988-08-01 |
| Radiation Therapy After Prostatectomy in Treating Patients With Stage III Prostate Cancer (NCT00394511) | National Cancer Institute (NCI) | 1988-08-01 |
| Optic Neuritis Treatment Trial (ONTT) (NCT00000146) | National Eye Institute (NEI) | 1988-07-01 |
| Radiation Therapy or No Further Treatment Following Surgery in Treating Patients With Cancer of the Uterus (NCT00002459) | European Organisation for Research and Treatment of Cancer - EORTC | 1988-04-01 |
| Advanced Glaucoma Intervention Study (AGIS) (NCT00000148) | National Eye Institute (NEI) | 1988-04-01 |
| Myocardial Infarction Triage and Intervention Project (MITI) (NCT00000468) | University of Washington | 1988-04-01 |
| Combination Chemotherapy in Treating Children With Neuroblastoma (NCT00003093) | Children's Oncology Group | 1988-03-01 |
| Antioxidant Supplement and Reduction of Metachronous Adenomas of the Large Bowel: a Double Blind Randomized Trial (NCT01437826) | IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy | 1988-03-01 |
| Intraperitoneal Versus Extraperitoneal Colostomy (NCT00964379) | Mayo Clinic | 1988-01-01 |
| Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection (NCT01203345) | NICHD Neonatal Research Network | 1988-01-01 |
| Diet and Breast Cancer Prevention Trial (NCT00148057) | University Health Network, Toronto | 1988-01-01 |
| Clinical Use and Safety of the Fentanyl Transdermal Therapeutic System (TTS) in the Management of Pain in Patients With Cancer (NCT00269763) | Alza Corporation, DE, USA | 1987-10-01 |
| Use of Somatropin in Turner Syndrome (NCT01518036) | Novo Nordisk A/S | 1987-09-14 |
| Adjuvant Hormone Therapy in Treating Women With Operable Breast Cancer (NCT00002460) | Cancer Research UK | 1987-09-01 |
| Child and Adolescent Trial for Cardiovascular Health (CATCH) (NCT00000467) | National Heart, Lung, and Blood Institute (NHLBI) | 1987-09-01 |
| Postmenopausal Estrogen/Progestin Interventions (PEPI) (NCT00000466) | National Heart, Lung, and Blood Institute (NHLBI) | 1987-09-01 |
| Magnesium Sulfate to Prevent Brain Injury in Premature Infants (NCT00065949) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1987-08-01 |
| Extracorporeal Carbon Dioxide Removal for Acute Respiratory Distress Syndrome (NCT00000572) | Intermountain Health Care, Inc. | 1987-06-01 |
| Emory Angioplasty Versus Surgery Trial (EAST) (NCT00000465) | National Heart, Lung, and Blood Institute (NHLBI) | 1987-06-01 |
| Osteosarcoma Study #2: A Randomized Trial of Pre-Surgical Chemotherapy vs. Immediate Surgery and Adjuvant Chemotherapy in the Treatment of Non-Metastatic Osteosarcoma. A Pediatric Oncology Group Phase III Study (NCT00001217) | National Cancer Institute (NCI) | 1987-05-01 |
| Radiation Therapy With or Without Goserelin and Cyproterone in Treating Patients With Prostate Cancer (NCT00849082) | European Organisation for Research and Treatment of Cancer - EORTC | 1987-05-01 |
| Post Coronary Artery Bypass Graft (CABG) Study (NCT00000463) | National Heart, Lung, and Blood Institute (NHLBI) | 1987-04-01 |
| Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) (NCT00000464) | University of Washington | 1987-04-01 |
| Bypass Angioplasty Revascularization Investigation (BARI) (NCT00000462) | National Heart, Lung, and Blood Institute (NHLBI) | 1987-04-01 |
| Dietary Intervention Study in Children (DISC) (NCT00000459) | National Heart, Lung, and Blood Institute (NHLBI) | 1986-12-01 |
| A Randomized Phase III Study of Intensive Consolidation With High Dose Cytosine Arabinoside in Acute Myelogenous Leukemia (AML-8B) (NCT01324063) | European Organisation for Research and Treatment of Cancer - EORTC | 1986-11-01 |
| Collaborative Ocular Melanoma Study (COMS) (NCT00000124) | National Eye Institute (NEI) | 1986-11-01 |
| Trials of Hypertension Prevention (TOHP) (NCT00000528) | National Heart, Lung, and Blood Institute (NHLBI) | 1986-09-01 |
| Cardiac Arrhythmia Suppression Trial (CAST) (NCT00000526) | National Heart, Lung, and Blood Institute (NHLBI) | 1986-08-01 |
| Diuretics, Hypertension, and Arrhythmias Clinical Trial (NCT00000525) | University of California, San Francisco | 1986-07-01 |
| Collaborative Corneal Transplantation Studies (CCTS) (NCT00000137) | National Eye Institute (NEI) | 1986-05-01 |
| Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantation (NCT00002456) | Fred Hutchinson Cancer Center | 1986-05-01 |
| Efficacy of the Fentanyl Transdermal Therapeutic System (TTS) in the Management of Pain in Patients With Cancer (NCT00269737) | Alza Corporation, DE, USA | 1986-05-01 |
| Further Studies of Attention Deficit Disorder - Residual Type (RT) (NCT00693212) | University of Utah | 1986-02-01 |
| Trial of Inspiratory Muscle Rest and Exercise in Chronic Obstructive Lung Disease (NCT00000571) | McGill University | 1986-02-01 |
| Human Surfactant Treatment of Respiratory Distress Syndrome Bicenter Trial (NCT00000570) | National Heart, Lung, and Blood Institute (NHLBI) | 1986-01-01 |
| Fluorouracil Filtering Surgery Study (FFSS) (NCT00000122) | National Eye Institute (NEI) | 1985-09-01 |
| The Silicone Study (NCT00000140) | National Eye Institute (NEI) | 1985-09-01 |
| Studies of Left Ventricular Dysfunction (SOLVD) (NCT00000516) | National Heart, Lung, and Blood Institute (NHLBI) | 1985-07-01 |
| Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) (NCT00000518) | University of Utah | 1985-07-01 |
| Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF) (NCT00000517) | Massachusetts General Hospital | 1985-07-01 |
| Long-Term Oral Acyclovir Usage to Prevent Herpes Zoster Virus Infection After Bone Marrow Transplant (NCT00209352) | Fred Hutchinson Cancer Center | 1985-06-01 |
| MARS - Monitored Atherosclerosis Regression Study (NCT00116870) | Merck Sharp & Dohme LLC | 1985-06-01 |
| Clinical Trial of Eye Prophylaxis in the Newborn (NCT00000120) | National Eye Institute (NEI) | 1985-01-01 |
| Krypton-Argon Regression of Neovascularization Study (KARNS) (NCT00000153) | National Eye Institute (NEI) | 1984-12-01 |
| Lung Health Study (LHS) I and III (NCT00000568) | National Heart, Lung, and Blood Institute (NHLBI) | 1984-09-01 |
| Hutchinson Smoking Prevention Project (NCT00115869) | Fred Hutchinson Cancer Center | 1984-09-01 |
| High Frequency Ventilation in Premature Infants (HIFI) (NCT00000567) | National Heart, Lung, and Blood Institute (NHLBI) | 1984-08-01 |
| Randomized Trial of Dietary Intervention Therapy in Obese Hypertensives (DITOH) (NCT00000515) | National Heart, Lung, and Blood Institute (NHLBI) | 1984-07-01 |
| Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium Complex (NCT03164291) | The University of Texas Health Science Center at Tyler | 1984-06-01 |
| Systolic Hypertension in the Elderly Program (SHEP) (NCT00000514) | National Heart, Lung, and Blood Institute (NHLBI) | 1984-06-01 |
| Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa (NCT00000114) | National Eye Institute (NEI) | 1984-05-01 |
| Trial of Antihypertensive Intervention Management (NCT00000513) | National Heart, Lung, and Blood Institute (NHLBI) | 1984-04-01 |
| The Prism Adaptation Study (PAS) (NCT00000121) | National Eye Institute (NEI) | 1984-03-01 |
| Liver Infusions of Fluorouracil in Treating Patients With Dukes' A, Dukes' B, or Dukes' C Colon Cancer Undergoing Surgery (NCT00427310) | NSABP Foundation Inc | 1984-03-01 |
| Glaucoma Laser Trial (GLT) Glaucoma Laser Trial Followup Study (GLTFS) (NCT00000144) | National Eye Institute (NEI) | 1984-01-01 |
| A Study of the Safety and Effectiveness of Levofloxacin Compared With Ceftriaxone Sodium or Cefuroxime Axetil in the Treatment of Adults With Pneumonia (NCT00257049) | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 1984-01-01 |
| Familial Atherosclerosis Treatment Study (NCT00000512) | University of Washington | 1984-01-01 |
| Potassium and Sodium to Control Blood Pressure in Hypertensives (NCT00000509) | University of Minnesota | 1983-09-01 |
| Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) (NCT00000566) | National Heart, Lung, and Blood Institute (NHLBI) | 1983-09-01 |
| Platelet-Inhibitor Drug Trial in Coronary Angioplasty (NCT00000510) | National Heart, Lung, and Blood Institute (NHLBI) | 1983-09-01 |
| Stanford Coronary Risk Intervention Project (SCRIP) (NCT00000508) | Stanford University | 1983-09-01 |
| Sorbinil Retinopathy Trial (SRT) (NCT00000159) | National Eye Institute (NEI) | 1983-08-01 |
| Intravenous Streptokinase in Acute Myocardial Infarction (NCT00000507) | University of Washington | 1983-08-01 |
| Penicillin Prophylaxis in Sickle Cell Disease (PROPS) (NCT00000585) | National Heart, Lung, and Blood Institute (NHLBI) | 1983-08-01 |
| Transfusion-Transmitted Cytomegalovirus Prevention in Neonates (NCT00000584) | National Heart, Lung, and Blood Institute (NHLBI) | 1983-07-01 |
| Thrombolysis in Myocardial Infarction (TIMI) (NCT00000505) | National Heart, Lung, and Blood Institute (NHLBI) | 1983-04-01 |
| Randomized Clinical Trial of Non-Surgical Reperfusion of the Coronary Arteries (NCT00000503) | National Heart, Lung, and Blood Institute (NHLBI) | 1982-08-01 |
| Exercise Training and Plasma Lipoproteins in Man (NCT00000519) | Stanford University | 1982-07-01 |
| Randomized Trial of Aspirin and Cataracts in U.S. Physicians (NCT00000157) | National Eye Institute (NEI) | 1982-04-01 |
| Randomized Trial of Beta-Carotene and Macular Degeneration (NCT00000152) | National Eye Institute (NEI) | 1982-04-01 |
| Multi-Center Trial of Anti-Thymocyte Globulin in Treatment of Aplastic Anemia and Other Hematologic Disorders (NCT00000597) | National Heart, Lung, and Blood Institute (NHLBI) | 1982-03-01 |
| Evaluation of SC-V Versus Conventional CPR (NCT00000502) | National Heart, Lung, and Blood Institute (NHLBI) | 1981-09-01 |
| Physicians' Health Study (NCT00000500) | Brigham and Women's Hospital | 1981-09-01 |
| Prospective Evaluation of Radial Keratotomy (PERK) Study (NCT00000129) | National Eye Institute (NEI) | 1981-04-01 |
| Cholesterol-Lowering Atherosclerosis Study (CLAS) (NCT00000599) | National Heart, Lung, and Blood Institute (NHLBI) | 1980-06-01 |
| Control of Hypertension by Non-Pharmacologic Means (NCT00000498) | National Heart, Lung, and Blood Institute (NHLBI) | 1980-04-01 |
| Dietary Intervention Study for Hypertension (DISH) (NCT00000497) | University of Mississippi Medical Center | 1980-01-01 |
| Platelet Drug Trial in Coronary Disease Progression (NCT00000496) | National Heart, Lung, and Blood Institute (NHLBI) | 1979-12-01 |
| Early Treatment Diabetic Retinopathy Study (ETDRS) (NCT00000151) | National Eye Institute (NEI) | 1979-12-01 |
| The Treatment of Stage I and II Carcinoma of the Breast With Mastectomy and Axillary Dissection Versus Excisional Biopsy, Axillary Dissection, and Definitive Irradiation (NCT01468883) | National Cancer Institute (NCI) | 1979-09-04 |
| Macular Photocoagulation Study (MPS) (NCT00000158) | National Eye Institute (NEI) | 1979-02-01 |
| Prevention of Hypertension: A Randomized Trial (NCT00000495) | Northwestern University | 1978-12-01 |
| Hepatitis B Vaccine Clinical Trial (NCT00000583) | National Heart, Lung, and Blood Institute (NHLBI) | 1978-11-01 |
| Management of Patent Ductus in Premature Infants (NCT00000494) | National Heart, Lung, and Blood Institute (NHLBI) | 1978-09-01 |
| Cooperative Study of Factor VIII Inhibitors (NCT00000582) | National Heart, Lung, and Blood Institute (NHLBI) | 1978-07-01 |
| The Berkeley Orthokeratology Study (NCT00000123) | National Eye Institute (NEI) | 1978-01-01 |
| Multicenter Investigation of Limitation of Infarct Size (MILIS) (NCT00000493) | National Heart, Lung, and Blood Institute (NHLBI) | 1977-09-01 |
| Fluorouracil, Semustine, and Vincristine Compared With BCG in Treating Patients With Dukes' B or Dukes' C Colon Cancer That Has Been Removed By Surgery (NCT00427570) | NSABP Foundation Inc | 1977-09-01 |
| Beta-Blocker Heart Attack Trial (BHAT) (NCT00000492) | National Heart, Lung, and Blood Institute (NHLBI) | 1977-09-01 |
| Branch Vein Occlusion Study (NCT00000162) | National Eye Institute (NEI) | 1977-07-01 |
| Clinical Study of Intermittent Positive Pressure Breathing (IPPB) (NCT00000565) | National Heart, Lung, and Blood Institute (NHLBI) | 1976-11-01 |
| Diabetic Retinopathy Vitrectomy Study (DRVS) (NCT00000154) | National Eye Institute (NEI) | 1976-10-01 |