| REduced-dose Steroid PrOtocol for Childhood Nephrotic SyndromE (RESPONSE) (NCT06635720) | The Hospital for Sick Children | 2024-11-01 |
| Efficacy and Safety of Tamsulosin for Children with Posterior Urethral Valve. (NCT06737016) | Mansoura University | 2024-11-01 |
| TDLN-sparing RT Plus Immunotherapy and Chemotherapy in Locally Advanced ESCC (NCT06676449) | Fudan University | 2024-11-01 |
| A Phase 3 Study to Evaluate the Immunogenicity and Safety of Minhai's PCV13-DT/TT Vaccine As Compared to Pfizer's PCV13 Vaccine (NCT06608199) | Beijing Minhai Biotechnology Co., Ltd | 2024-11-01 |
| High Versus Lower Intensity Surveillance Following Resection of Retroperitoneal Sarcoma (NCT06480396) | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 2024-11-01 |
| SBRT Combined With PD-1 Inhibitor and Chemotherapy in Early-stage TNBC (NCT06627712) | West China Hospital | 2024-11-01 |
| Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery (NCT06675500) | Ain Shams University | 2024-11-01 |
| Non-Invasive Pulsed Radiofrequency for the Treatment of Neuropathic Pain (NCT06185816) | Stanford University | 2024-11-01 |
| Does Perioperative Intravenous Magnesium Affect Postoperative Quality of Recovery in Craniotomy Surgery Patients? (NCT05049707) | Thomas Jefferson University | 2024-11-01 |
| Efficacy and Safety of N-Acetylcysteine Versus Alpha-Lipoic Acid in Colistin-Induced Nephrotoxicity (NCT06650384) | Ain Shams University | 2024-11-01 |
| Oxyhydrogen Nanobubble Infusion as a Complementary Therapy in Patients With Parkinsonism (NCT07466381) | dr. Siti Nurlaela, SpN | 2024-11-01 |
| Efficacy and Safety of LEAF-4L6715 for Acute Respiratory Distress Syndrome (NCT06640777) | LEAF4Life, Inc. | 2024-11-01 |
| Effectiveness of a Grape Seed Extract on Circulatory Measures in Healthy Adults (NCT06440252) | RDC Clinical Pty Ltd | 2024-10-31 |
| Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease (NCT06217302) | Alessandro Doria | 2024-10-31 |
| A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 Diabetes (NCT06649344) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2024-10-31 |
| Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAI (NCT06633718) | Qilu Pharmaceutical Co., Ltd. | 2024-10-31 |
| Study to Assess the Safety and Efficacy of ZX-7101A in Children Aged 5-11 Years With Influenza (NCT06669351) | Nanjing Zenshine Pharmaceuticals | 2024-10-31 |
| A Study of Simmitinib Versus Chemotherapy for Participants With Advanced Oesophageal Squamous Cell Carcinoma (NCT06656091) | Shanghai Runshi Pharmaceutical Technology Co., Ltd | 2024-10-31 |
| Hyperbaric Oxygen Therapy in HAMstring Injury (HOTHAM) Trial (NCT06526728) | JL Tol | 2024-10-30 |
| Quercetin Effect on Post-ceserean Pain (NCT06650891) | Future University in Egypt | 2024-10-30 |
| A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination With Pembrolizumab as First-Line Treatment for PD-L1 Negative Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NCT06711900) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2024-10-30 |
| Spironolactone Improved Children With Gene Mutations Related to NCOR (NCT06678685) | Qilu Hospital of Shandong University | 2024-10-30 |
| GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial (NCT06162715) | Vanderbilt University Medical Center | 2024-10-30 |
| Safety and Efficacy of Apixaban Versus Warfarin in Peritoneal Dialysis Patients With Non Valvular Atrial Fibrillation: a Prospective, Randomised, Open-label, Blinded End-point Trial (APIDP2) (NCT06045858) | University Hospital, Caen | 2024-10-30 |
| A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (NCT06601335) | Akeso | 2024-10-30 |
| A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy (NCT06541704) | Regeneron Pharmaceuticals | 2024-10-30 |
| A Phase III Study Comparing the Weight Loss Effects of Semaglutide Injection and Wegovy® (NCT06633783) | Hangzhou Jiuyuan Gene Engineering Co. Ltd., | 2024-10-30 |
| A Multicenter, Randomized, Controlled Trial of Prednisone Combined With Ursodeoxycholic Acid in the Treatment of Primary Biliary Cholangitis With Moderate to Severe Interface Hepatitis Characteristics (NCT06591468) | Han Ying | 2024-10-30 |
| The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study (NCT06377852) | American Society of Clinical Oncology | 2024-10-29 |
| A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants (NCT06663332) | Janssen Research & Development, LLC | 2024-10-29 |
| Lemborexant Treatment of Insomnia Linked to Epilepsy (NCT06262594) | University of Manitoba | 2024-10-29 |
| Efficacy and Safety of Skincare Serum and Cream for Anti-aging of Facial Skin (NCT06638905) | Goldman, Butterwick, Fitzpatrick and Groff | 2024-10-28 |
| Effectiveness of Intranasal Dexmedetomidine Premedication in Child Intubation (NCT06991647) | Indonesia University | 2024-10-28 |
| A Clinical Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab or Atezolizumab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma (NCT06618664) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2024-10-28 |
| A Study of BGM0504 Injection in Participants with Obesity or Overweight (NCT06704581) | BrightGene New Bio-Medical Technology(Wuxi) Co.Ltd. | 2024-10-28 |
| Study to Assess Safety and Effectiveness of Slowly Increasing Dose and Food Effect of KarXT in Participants With Schizophrenia (NCT06572449) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2024-10-28 |
| Efficacy of Adenosine as Compared to Verapamil in Paroxysmal Supraventricular Tachycardia (pSVT) Patients (NCT06717685) | Rashid Latif Medical College | 2024-10-28 |
| Efficacy and Safety Study of Aprepitant Injection for Prevention of Post-operative Nausea and Vomiting (NCT06543966) | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 2024-10-28 |
| Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Chinese Pediatric Participants 1 to <12 Years of Age With Influenza Symptoms (NCT06774859) | Hoffmann-La Roche | 2024-10-27 |
| Using of Bone Marrow Stem Cell Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Reconstruction of Upper Jaw Bony Cystic Defects, Comparing with Platelet Rich Fibrin with Bone Graft (NCT06662604) | Cairo University | 2024-10-26 |
| The Experiment of Noiiglutide Injection in Type 2 Diabetes Patients (NCT06649773) | Jiangsu HengRui Medicine Co., Ltd. | 2024-10-25 |
| MDMA-assisted Massed Prolonged Exposure for PTSD (NCT06117306) | Healing Breakthrough | 2024-10-25 |
| Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta (NCT06636071) | Ultragenyx Pharmaceutical Inc | 2024-10-25 |
| A Study of Andecaliximab in Participants With Fibrodysplasia Ossificans Progressiva (FOP) (NCT06508021) | Ashibio Inc | 2024-10-25 |
| The Effect of Methylene Blue Infiltrating Injection on Anal Pain After Milligan-Morgan Surgery: A Randomized Controlled Clinical Study (NCT06660680) | The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine | 2024-10-25 |
| A Study to Evaluate the Efficacy and Safety of Oral HRS-5965 in Adult Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy (NCT06593938) | Chengdu Suncadia Medicine Co., Ltd. | 2024-10-25 |
| A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Qifangfeixian Granules in the Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD) (NCT06674148) | Huilan Zhang | 2024-10-25 |
| A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (NCT06439082) | Novartis Pharmaceuticals | 2024-10-24 |
| A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3) (NCT06653153) | Eli Lilly and Company | 2024-10-24 |
| Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial (NCT06593431) | M.D. Anderson Cancer Center | 2024-10-23 |
| A Clinical Study of JMT101 in Combination With Osimertinib Versus Osimertinib Alone as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Sensitive Mutations (NCT06735391) | Shanghai JMT-Bio Inc. | 2024-10-23 |
| Clinical Trial of 13-Valent Pneumococcal Conjugate Vaccine (NCT06617715) | Sinovac Life Sciences Co., Ltd. | 2024-10-23 |
| Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma (NCT06337318) | National Cancer Institute (NCI) | 2024-10-23 |
| Phase 3 Study to Evaluate the Immunogenicity and Safety of Inactived Split Influenza Vaccine in Healthy Infants (NCT04381689) | Il-Yang Pharm. Co., Ltd. | 2024-10-23 |
| OBINOTUZUMAB Versus Cyclophosphamide + Glucocorticoids in Primary Membranous Nephropathy(Blossom Study) (NCT06781944) | Huashan Hospital | 2024-10-23 |
| The Sagittarius Trial (NCT06490536) | IFOM ETS - The AIRC Institute of Molecular Oncology | 2024-10-22 |
| A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight (NCT06649045) | Eli Lilly and Company | 2024-10-22 |
| Study to Evaluate the Efficacy and Safety of JP-1366 in the Prevention of NSAIDs-Induced Peptic Ulcers (NCT06439563) | Onconic Therapeutics Inc. | 2024-10-22 |
| A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. (NCT06629779) | Pfizer | 2024-10-22 |
| A Study in Chinese Patients With Acquired Blepharoptosis (NCT06683651) | Santen Pharmaceutical Co., Ltd. | 2024-10-22 |
| Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age (NCT06524882) | Jaeb Center for Health Research | 2024-10-22 |
| QL0911 for the Treatment of Cancer Treatment-Induced Thrombocytopenia (NCT06456528) | Qilu Pharmaceutical Co., Ltd. | 2024-10-22 |
| A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56 (NCT06668064) | EyePoint Pharmaceuticals, Inc. | 2024-10-22 |
| Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV. (NCT06321601) | Amgen | 2024-10-22 |
| Supplementation of Galatonol 300 mg / Striatin 30 mg in Postpartum Lactating Mothers (NCT06558071) | Dexa Medica Group | 2024-10-21 |
| Perioperative SDD to Prevent Infectious Complications After Esophagectomy (NCT05865743) | Radboud University Medical Center | 2024-10-21 |
| A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1). (NCT06551324) | Pfizer | 2024-10-21 |
| Amniotic Suspension Allograft Injection for Knee Osteoarthritis (NCT06704893) | Chang Gung Memorial Hospital | 2024-10-21 |
| Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill Patients (NCT07221370) | Riverside University Health System Medical Center | 2024-10-21 |
| Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated (NCT06613685) | Gilead Sciences | 2024-10-21 |
| A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis (NCT06624228) | UCB Biopharma SRL | 2024-10-21 |
| Long-term Extension Study of Ulviprubart (ABC008) in Subjects With Inclusion Body Myositis (NCT06450886) | Abcuro, Inc. | 2024-10-21 |
| REVERSE-Long COVID-19 With Baricitinib Study (NCT05858515) | Vanderbilt University Medical Center | 2024-10-21 |
| A Pilot Crossover Trial of Prophylactic Wilate Compared to Placebo for Heavy Menstrual Bleeding in Patients with VWD (NCT06205095) | Unity Health Toronto | 2024-10-21 |
| A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009) (NCT06623422) | Merck Sharp & Dohme LLC | 2024-10-21 |
| TPC Combined With Cadonilimab VS. TPC Alone in Anti-PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma (NCT06664983) | Sun Yat-sen University | 2024-10-21 |
| Open-Label Extension Study of Setmelanotide (NCT06596135) | Rhythm Pharmaceuticals, Inc. | 2024-10-21 |
| Protocol for Improvement of Therapy With Warfarin (NCT06789588) | University of Pernambuco | 2024-10-21 |
| Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID (NCT06631287) | Wes Ely | 2024-10-21 |
| Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age (NCT06250257) | Jimma University | 2024-10-21 |
| A Multi-center Evaluation of Aldafermin in a Randomized, Double-blind, Placebo-controlled Study in Subjects With Primary Sclerosing Cholangitis. (NCT06654726) | NGM Biopharmaceuticals, Inc | 2024-10-21 |
| AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced Biliary Tract Cancer (NCT06591520) | Akeso | 2024-10-20 |
| Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients (NCT06508710) | Assistance Publique - Hôpitaux de Paris | 2024-10-20 |
| Efficacy of Fecal Microbiota Transplantation in ICU Patients With Gastrointestinal Dysfunction-induced Enteral Nutrition Intolerance (NCT06603883) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2024-10-19 |
| Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation (NCT06780930) | Servier | 2024-10-18 |
| A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer (NCT06662786) | Janssen Research & Development, LLC | 2024-10-18 |
| A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia (NCT06544499) | argenx | 2024-10-18 |
| Evaluation of Efficacy and Safety of Oral Minoxidil 1 mg in Female Androgenetic Alopecia (NCT05888922) | Industrial Farmacéutica Cantabria, S.A. | 2024-10-17 |
| Efficacy and Safety Study of Levomilnacipran Hydrochloride Extended-Release Capsules in Major Depressive Disorder (NCT07253207) | Zhejiang Huahai Pharmaceutical Co., Ltd. | 2024-10-17 |
| Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache (NCT06621329) | University of California, Davis | 2024-10-17 |
| A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis (NCT06055959) | UCB Biopharma SRL | 2024-10-16 |
| Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) (NCT06625320) | Revolution Medicines, Inc. | 2024-10-16 |
| Nebulized Ketamine for the Treatment of Major Depressive Disorder (NCT06752759) | Theresa Jacob, PhD, MPH | 2024-10-16 |
| Rituximab Induced Remission in Patients With Chronic Inflammatory Demyelinating Polyneuropathy (NCT06714838) | Amsterdam University Medical Center (UMC), Location Academic Medical Center (AMC) | 2024-10-16 |
| Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response (NCT06641089) | MoonLake Immunotherapeutics AG | 2024-10-15 |
| Stereotactic Body Radiotherapy Followed by Tislelizumab Plus Platinum-based Chemotherapy Versus Tislelizumab Plus Platinum-based Chemotherapy as Neoadjuvant Therapy in Patients With Resectable Stage Ⅱ-Ⅲ Non-small Cell Lung Cancer: A Phase Ⅲ, Randomized, Multicenter, Prospective Study (NCT06598527) | Yang Hong | 2024-10-15 |
| A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological Features (NCT06564844) | AstraZeneca | 2024-10-15 |
| Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis Naive to Biologic Disease-Modifying Antirheumatic Drug (NCT06641076) | MoonLake Immunotherapeutics AG | 2024-10-15 |
| To Evaluate Efficacy and Safety of TopicalKX-826 Solution in Chinese Male Patients With Androgenetic Alopecia (NCT06622824) | Suzhou Kintor Pharmaceutical Inc, | 2024-10-15 |
| Bronchoprovocation Study to Demonstrate the Pharmacodynamic Bioequivalence of Albuterol Sulfate HFA Inhalation Aerosol (E.Q. 90 mcg of Albuterol Base/Inh) of Macleods Pharmaceuticals Ltd (NCT06618105) | Macleods Pharmaceuticals Ltd | 2024-10-15 |