| Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC Patients (NCT06696794) | Shaogang Wang | 2025-02-17 |
| Toripalimab vs. Placebo Wtih GP Induction Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma (NCT06712888) | Sun Yat-sen University | 2025-02-17 |
| A Phase III Clinical Study to Assess the Efficacy and Safety of GZR4 in Insulin-naive Subjects With Type 2 Diabetes Mellitus (T2DM) (NCT06767735) | Gan & Lee Pharmaceuticals. | 2025-02-17 |
| A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease (NCT06612268) | Novo Nordisk A/S | 2025-02-17 |
| Head-to-head Study of Tegoprazan 50 mg BID Plus Amoxicillin 1 g TID vs. Vonoprazan 20 mg BID Plus Amoxicillin 1 g TID for H. Pylori Eradication (NCT07242456) | First People's Hospital of Hangzhou | 2025-02-17 |
| Clinical Study of Fasudil Hydrochloride and PD1 Inhibitor Combined With Androgen Deprivation in Neoadjuvant Therapy of Prostate Cancer (NCT06861192) | baotai Liang | 2025-02-16 |
| BiodEgradable Soaked Amiodarone paTch Use for the Prevention of Atrial Fibrillation After Cardiac Surgery (NCT06722196) | Jilin Heart Hospital | 2025-02-15 |
| Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars (NCT06237231) | EMS | 2025-02-15 |
| Ultrasound Assessment of Metoclopramide's Effect on Stomach Volume in Urgent Pediatric Trauma Surgery (NCT06793267) | Assiut University | 2025-02-15 |
| Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children. (NCT06272409) | EMS | 2025-02-15 |
| Probiotic Supplements in Osteoarthritis (NCT07364578) | Beni-Suef University | 2025-02-15 |
| A Phase III Clinical Study to Assess the Efficacy and Safety of GZR4 in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin (NCT06767748) | Gan & Lee Pharmaceuticals. | 2025-02-15 |
| GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes (NCT06630585) | University of Bern | 2025-02-14 |
| The Research of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression (NCT06827431) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2025-02-14 |
| Phase 3, Multi-center, Prospective, Randomized, Double-blind, Placebo- Controlled Study to Evaluate the Effectiveness and Safety of ZP5-9676 for the Treatment of Soil Transmitted Helminthiasis (STH) (NCT06128447) | Zero Point Five Therapeutics | 2025-02-14 |
| Efficacy and Safety of SP-8203 (Otaplimastat) in Patients With Acute Ischemic Stroke Receiving Thrombolytic Standard of Care (NCT06660719) | Shin Poong Pharmaceutical Co. Ltd. | 2025-02-14 |
| A Study of SC0062 Capsule for the Treatment of IgA Nephropathy with Proteinuria (NCT06819826) | Biocity Biopharmaceutics Co., Ltd. | 2025-02-14 |
| A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years (NCT06810505) | AbbVie | 2025-02-13 |
| A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus (NCT06778967) | Gan & Lee Pharmaceuticals. | 2025-02-13 |
| A Phase III Study to Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Naive to Complement Inhibitor Therapy (NCT06799546) | Haisco Pharmaceutical Group Co., Ltd. | 2025-02-13 |
| The Efficacy and Safety of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2 (NCT06523400) | Lupin Ltd. | 2025-02-13 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia (NCT06723652) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2025-02-13 |
| A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps (NCT06834347) | Sanofi | 2025-02-12 |
| Assessment of Immunogenicity, Reactogenicity and Safety of the Drug GNG-DE in Comparison With the Reference Drug (NCT06834100) | NPO Petrovax | 2025-02-12 |
| A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE) (NCT06908226) | Longboard Pharmaceuticals | 2025-02-12 |
| Colchicine in Chronic Kidney Disease Patients (NCT06998862) | Hospital General Universitario Gregorio Marañon | 2025-02-12 |
| A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma (NCT06738251) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2025-02-12 |
| Pyrotinib and Trastuzumab Combined With Dalpiciclib Versus Combined With Docetaxel in Advanced HER2-Positive Breast Cancer (NCT07615751) | Fudan University | 2025-02-12 |
| Continuous Positive Airway Pressure (CPAP) Assisted Radiotherapy in Breast Cancer (NCT07373782) | Universitaire Ziekenhuizen KU Leuven | 2025-02-11 |
| A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma (NCT06822738) | AbbVie | 2025-02-11 |
| The Prospective, Double-blind, Multicenter, Placebo-controlled, Randomized, Comparative Clinical Trial (NCT07391319) | JSC NextGen | 2025-02-11 |
| Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction (NCT06518694) | Assistance Publique - Hôpitaux de Paris | 2025-02-11 |
| The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (NCT05973786) | Dr. Inge Winter | 2025-02-11 |
| A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE) (NCT06858579) | Dianthus Therapeutics | 2025-02-10 |
| Home-based Cycling for People With Lumbar Spinal Stenosis (NCT04075539) | Assistance Publique - Hôpitaux de Paris | 2025-02-10 |
| A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity (NCT06780449) | Novo Nordisk A/S | 2025-02-10 |
| Study of Oral Atogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine (NCT06806293) | AbbVie | 2025-02-10 |
| This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations. (NCT06616025) | Neuraptive Therapeutics Inc. | 2025-02-10 |
| A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) (NCT06533098) | Janssen Research & Development, LLC | 2025-02-10 |
| Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal Bleed (NCT06815770) | Institute of Liver and Biliary Sciences, India | 2025-02-10 |
| Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2) (NCT06561061) | Indiana University | 2025-02-10 |
| Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in Women With Primary Infertility (NCT06769204) | Cairo University | 2025-02-10 |
| ROLE OF FOLIC ACID IN THE MANAGEMENT OF ADJUVANT ENDOCRINE THERAPY-INDUCED HOT FLASHES IN BREAST CANCER PATIENTS (NCT06774885) | Future University in Egypt | 2025-02-09 |
| Phase III Clinical Trial of Quadrivalent Influenza Virus Split Vaccine (NCT06800950) | Institute of Medical Biology, Chinese Academy of Medical Sciences | 2025-02-08 |
| Study Evaluating the Safety of a Recombinant Acellular Pertussis Vaccine in Adults (NCT06798831) | BioNet-Asia Co., Ltd. | 2025-02-08 |
| The Efficacy and Safety of HRS8179 in Severe Cerebral Edema Following Large Hemispheric Infarction (NCT06732648) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2025-02-07 |
| AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer (NCT06767527) | Akeso | 2025-02-07 |
| Gut Microbiome Profiles in Patients with Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544). (NCT06799351) | Bernardino Clavo, MD, PhD | 2025-02-07 |
| Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy (NCT06706544) | Bernardino Clavo, MD, PhD | 2025-02-07 |
| A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis (NCT06744920) | Novartis Pharmaceuticals | 2025-02-07 |
| Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer (NCT06619236) | Genmab | 2025-02-07 |
| Adjuvant Abemaciclib for Locoregional Recurrence of HR-positive, HER2-negative Breast Cancer (JCOG2313, AURA) (NCT07190443) | Japanese Foundation for Cancer Research | 2025-02-07 |
| A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps (NCT06834360) | Sanofi | 2025-02-06 |
| PRODIGE 90 - (FFCD 2204) Neoadjuvant Dostarlimab with Short Course Radiotherapy in a Watch-and-wait Strategy for Microsatellite Unstable or Mismatch Repair-deficient Locally Advanced Rectal Cancer Patients (NCT06762405) | Centre Hospitalier Universitaire Dijon | 2025-02-06 |
| Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types (NCT06782412) | KU Leuven | 2025-02-06 |
| Cannabidiol as add-on Therapy for Children With Refractory Epilepsy (CBD-uN1que), a High-quality Individualized Approach: a Series of N-of-1 Trials (NCT07668856) | UMC Utrecht | 2025-02-06 |
| Efgartigimod in IVIG Dependent Myasthenia Gravis Patients (NCT06765161) | Clinique Neuro-Outaouais | 2025-02-06 |
| Bacteriophages in Addition to Antibiotics for the Treatment of Patients With Infective Endocarditis (NCT06870409) | University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba) | 2025-02-05 |
| A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum (NCT06624670) | LEO Pharma | 2025-02-05 |
| Polymeric Micellar Paclitaxel for Metastatic Pancreatic Cancer (NCT06752811) | Shanghai Yizhong Pharmaceutical Co., Ltd. | 2025-02-05 |
| A Phase III Clinical Study of Valsartan Oral Solution for the Treatment of Hypertension in Children and Adolescents (NCT06863987) | Shandong New Time Pharmaceutical Co., LTD | 2025-02-05 |
| A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD (NCT06709014) | Annovis Bio Inc. | 2025-02-04 |
| Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free. (NCT06431633) | Fundación GECP | 2025-02-04 |
| Personalized Rituximab Treatment Based on Artificial Intelligence in Membranous Nephropathy (iRITUX) (NCT06341205) | Centre Hospitalier Universitaire de Nice | 2025-02-04 |
| Is Adaptive SBRT for Prostate vs Image-guided Radiotherapy a True Evolution (ASPIRE) (NCT06825091) | University Health Network, Toronto | 2025-02-04 |
| A Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED) (NCT06812325) | Viridian Therapeutics, Inc. | 2025-02-03 |
| Severe Acute Malnutrition and Child Development Clinical Trial in Mwanza (NCT06781918) | National Institute for Medical Research, Tanzania | 2025-02-03 |
| EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma (NCT06556563) | NovoCure GmbH | 2025-02-03 |
| Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery (NCT06843538) | TriHealth Inc. | 2025-02-03 |
| Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer (NCT06712355) | BioNTech SE | 2025-02-03 |
| Effect of Sacubitril-Valsartan on Cardiac Structure and Function (NCT06693674) | Mayo Clinic | 2025-02-03 |
| High-protein Oral Supplement With Liposomal Curcumin in Adults Undergoing Hemodialysis. (NCT06381076) | University of Florida | 2025-02-03 |
| Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplasia (BPD) (NCT06897839) | Airway Therapeutics, Inc. | 2025-02-03 |
| Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer (NCT06625034) | Mayo Clinic | 2025-02-02 |
| Alpha Lipoic Acid in Pediatrics on Hemodialysis (NCT06286098) | Ain Shams University | 2025-02-02 |
| a Study of QL1706 or QL1604 in Patients With Limited-stage Small Cell Lung Cancer After Chemoradiotherapy. (NCT06789796) | Qilu Pharmaceutical Co., Ltd. | 2025-02-01 |
| A Study to Evaluate the Efficacy and Safety of Co-administration of AD-2281 and AD-2282 (NCT06747936) | Addpharma Inc. | 2025-02-01 |
| Non-Inferiority Study on MRNA-lncRNA Model in Low-Risk Triple-Negative Breast Cancer Patients (NCT06795503) | Fudan University | 2025-02-01 |
| Transcranial Magnetic Stimulation in Patients with Dual Disorders (NCT06765824) | Cardenal Herrera University | 2025-02-01 |
| Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke After Endovascular Treatment (NCT06788626) | Wei Hu | 2025-02-01 |
| Laparoscopic Antibiotic Lavage to Prevent Intra-abdominal Abscess Formation in Complicated Appendicitis (NCT06841003) | Spaarne Gasthuis | 2025-02-01 |
| Efficacy and Safety Study of QLG1080 in Patients With Hormone-sensitive Advanced Prostate Cancer (NCT06837896) | Qilu Pharmaceutical Co., Ltd. | 2025-02-01 |
| Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea (NCT06268054) | EMS | 2025-02-01 |
| Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma (NCT05439278) | Severance Hospital | 2025-02-01 |
| Efficacy and Safety of the DTT106 in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia (NCT06264414) | EMS | 2025-02-01 |
| Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE (NCT06679881) | Pharvaris Netherlands B.V. | 2025-02-01 |
| A Comparative Evaluation of Mosapride Versus Metoclopramide for Enteral Feeding Intolerance in Critically Ill Patients (NCT06826443) | Ain Shams University | 2025-02-01 |
| Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma (NCT06419946) | Vastra Gotaland Region | 2025-02-01 |
| Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous Chorioretinopathy (NCT06809751) | Mohsen Pourazizi | 2025-02-01 |
| CompARing Between CO2 Phenylephrine and Phenylephrine Only Treatment in Patients With proGrEssing Cerebral infarctioN (NCT06770426) | Yonsei University | 2025-02-01 |
| Adjuvant Cerebroprotection Using Normobaric Hyperoxia in Pre-hospital Patients with Suspected Stroke (NCT06801457) | Capital Medical University | 2025-02-01 |
| Immuno-pet IMaging ResPonses AdministeRed Immune CheckpoiNt InhibiTor (NCT06218069) | Radboud University Medical Center | 2025-02-01 |
| Hyaluronic Acid Mouthwash as Adjunct (NCT07366398) | Cairo University | 2025-02-01 |
| "The Effect of Inhaled Nitroglycerin for COPD Patients (NCT06785337) | Beni-Suef University | 2025-02-01 |
| Efficacy and Safety of Nitazoxanide 600 Mg in the Outpatient Treatment of COVID-19 and Influenza (NCT06817096) | Azidus Brasil | 2025-02-01 |
| Comparison of the Efficacies of Two Novel Dose Dual Therapies in the First-line Helicobacter Pylori Eradication (NCT06811207) | Chang Gung Memorial Hospital | 2025-02-01 |
| The Efficacy and Safety of SHR-1314 in the Treatment of Pediatric Patients of Age 6 to <18 Years With Moderate to Severe Plaque Psoriasis (NCT06833307) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-02-01 |
| CCRT Followed by PD-1 Inhibitor Maintenance Therapy in Locally Advanced ESCC (NCT06964568) | Fudan University | 2025-02-01 |
| Lot Consistency Study of COVID-19 and Influenza Combination Vaccine (NCT06482359) | Novavax | 2025-02-01 |
| Semaglutide in Women With Polycystic Ovary Syndrome and Obesity (NCT06896981) | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 2025-02-01 |