| Intravenous Acetaminophen for Postoperative Delirium in Older Patients Recovering From Major Noncardiac Surgery (NCT06653465) | RenJi Hospital | 2025-06-01 |
| A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation (NCT06836024) | Hamilton Health Sciences Corporation | 2025-06-01 |
| Real-World Joint Outcomes After Selective Transition to Low-Dose Emicizumab in Pediatric Hemophilia A (NCT07439055) | Chulalongkorn University | 2025-06-01 |
| Saline Versus Balanced Crystalloid in Traumatic Brain Injury (NCT06953674) | University of Louisville | 2025-06-01 |
| Intra-Arterial Thrombolysis After SUCCESSful Reperfusion in Anterior Circulation Ischemic Stroke (NCT06768138) | Central Hospital, Nancy, France | 2025-06-01 |
| Low Dose Emicizumab vs Low Dose Factor VIII in Prophylaxis in Hemophilia A Patients (NCT06938659) | Dhaka Medical College | 2025-06-01 |
| Efficacy and Safety of Fruquintinib Combined With Sintilimab and Stereotactic Body Radiation Therapy (SBRT) for the Second-line and Higher-line Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma With Oligometastatic Progression (NCT06977061) | Queling Liu | 2025-06-01 |
| Comparison of Postoperative Analgesia in Erector Spinae Plane Block (ESPB) v/s Subcostal Transversus Abdominal Plane Block (STAP) in Adults Undergoing Laparoscopic Cholecystectomy. (NCT07469410) | Patel Hospital, Pakistan | 2025-06-01 |
| To Evaluate the Efficacy and Safety of Abaloparatide Injection (QLG2128) in the Treatment of Postmenopausal Women With Osteoporosis and at High Risk of Fracture (NCT06898060) | Qilu Pharmaceutical Co., Ltd. | 2025-06-01 |
| SHR - A1811 Versus Chemotherapy for Platinum-resistant Recurrent Epithelial Ovarian Cancer (NCT06990503) | Tongji Hospital | 2025-06-01 |
| Randomized Controlled Trial Comparing Remote Patient Monitoring vs Standard Care in IBD Patients Initiating or Changing Advanced Therapy (NCT07043036) | Resilience | 2025-06-01 |
| A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC) (NCT06959693) | Sun Yat-sen University | 2025-06-01 |
| NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) (NCT06963021) | Neurocrine Biosciences | 2025-05-30 |
| A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series (NCT06947499) | LG Chem | 2025-05-30 |
| Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (NCT06790966) | PDS Biotechnology Corp. | 2025-05-30 |
| Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-BEYOND (NCT06954155) | Beijing Tiantan Hospital | 2025-05-30 |
| Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET (NCT06784752) | Novartis Pharmaceuticals | 2025-05-30 |
| A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain. (NCT06917404) | Paradigm Biopharmaceuticals Ltd. | 2025-05-29 |
| A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors (NCT06970743) | BeOne Medicines | 2025-05-29 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain (NCT07035093) | Eli Lilly and Company | 2025-05-29 |
| Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRC (NCT06844487) | Jean-Pierre Van geertruyden | 2025-05-29 |
| A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event (NCT07000123) | AstraZeneca | 2025-05-28 |
| A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease (NCT06976268) | Biohaven Therapeutics Ltd. | 2025-05-28 |
| A Study to Assess the Efficacy and Safety of Firmonertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB - IIIB NSCLC With Uncommon Epidermal Growth Factor Receptor (EGFR) Mutations, Following Complete Surgical Resection With or Without Adjuvant Chemotherapy（FIRMOST） (NCT07010419) | Allist Pharmaceuticals, Inc. | 2025-05-28 |
| Platform Trial For Cryptococcal Meningitis (PLATFORM-CM) (NCT06666322) | David Boulware | 2025-05-28 |
| Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response (NCT06592924) | Canadian Cancer Trials Group | 2025-05-28 |
| The Beat Pain Better Trial (NCT06932887) | University of Utah | 2025-05-28 |
| Safety and Efficacy Evaluation of GC101 Gene Therapy Via Intrathecal (IT) Injectionin the Treatment of Patients With Type 2 Spinal Muscular Atrophy (SMA) - Phase III (NCT06971094) | GeneCradle Inc | 2025-05-27 |
| Low Frequency Right Dorsolateral Pre Frontal Cortical Repetitive TMS for Bipolar Depression (NCT06986460) | Tyler Kaster | 2025-05-27 |
| A Study of Switching to Picankibart in Chinese Patients With Plaque Psoriasis With an Inadequate Response to Interleukin-17 Monoclonal Antibody Therapy (NCT06945107) | Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. | 2025-05-27 |
| AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer (NCT06951503) | Akeso | 2025-05-27 |
| Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis (NCT07039916) | Immunovant Sciences GmbH | 2025-05-27 |
| Fluzoparib+Bevacizumab/Dietary Intervention vs Fluzoparib Monotherapy as First-line Maintenance in HRD+/- Advanced Ovarian Cancer (NCT06954584) | Tongji Hospital | 2025-05-27 |
| Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's Disease (NCT06873334) | Skyhawk Therapeutics, Inc. | 2025-05-27 |
| A Study to Compare Efficacy and Safety of CT-P55 and Cosentyx in Patients With Moderate to Severe Psoriasis (NCT06630559) | Celltrion | 2025-05-26 |
| A Study to Assess Safety and Effectiveness of HArmonyCa Lidocaine Injectable Gel for Restoration and/or Creation of Mid-Face Volume in Adult Participants (NCT07032597) | AbbVie | 2025-05-26 |
| Immunogenicity and Safety of I-HAV in Healthy Thai Children and Adolescents Lacking Protective Antibody After L-HAV (NCT06978621) | Chiang Mai University | 2025-05-25 |
| Antagonization of Heparin With Protamine Sulfate After TAVI (NCT06215378) | Assistance Publique - Hôpitaux de Paris | 2025-05-25 |
| Open-label Study to Evaluate Metreleptin in Children Under 6 Years of Age With Generalised Lipodystrophy (NCT06502990) | Amryt Pharma | 2025-05-23 |
| Pembrolizumab and Radiotherapy for Oligometastatic Head and Neck Cancer (NCT05815927) | European Organisation for Research and Treatment of Cancer - EORTC | 2025-05-23 |
| Intermittent Androgen Deprivation Therapy in the Era of AR Pathway Inhibitors (NCT05974774) | European Organisation for Research and Treatment of Cancer - EORTC | 2025-05-23 |
| Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE (NCT06853535) | Sichuan Provincial People's Hospital | 2025-05-23 |
| A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29) (NCT06952504) | Merck Sharp & Dohme LLC | 2025-05-22 |
| Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial) (NCT06616584) | SWOG Cancer Research Network | 2025-05-22 |
| Efficacy of an Adapted Antibiotherapy in Hurley Stage 2 Hidradenitis Suppurativa Patients (NCT05821478) | Institut Pasteur | 2025-05-22 |
| Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma. (NCT06697301) | Eikon Therapeutics | 2025-05-22 |
| A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN) (NCT06962800) | Biogen | 2025-05-22 |
| Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age (NCT06975878) | Sanofi | 2025-05-22 |
| Reduced Dose Radiotherapy vs Standard Dose Radiotherapy for Early Stage Nasopharyngeal Carcinoma (NCT06912698) | Hai-Qiang Mai,MD,PhD | 2025-05-22 |
| A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness (NCT06803654) | Bausch & Lomb Incorporated | 2025-05-22 |
| Phase 3 Randomized, Modified Double-blind, Active-controlled Safety Study on vYF in Adults (NCT07002060) | Sanofi | 2025-05-22 |
| A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer (NCT06901531) | Astellas Pharma Global Development, Inc. | 2025-05-22 |
| A Study to Evaluate the Efficacy and Safety of Treatment With CsA-PG Ophthalmic Gel in Dry Eye Patients (NCT06942793) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2025-05-20 |
| Efficacy of Striatin in Malnourished Children (NCT07089329) | Universitas Sriwijaya | 2025-05-20 |
| Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus Treatment (NCT06988527) | Dar Al Uloom University | 2025-05-20 |
| Efficacy and Safety of Xinyue Capsule in the Treatment of Heart Failure With Preserved Ejection Fraction (NCT06946095) | Beijing Anzhen Hospital | 2025-05-20 |
| A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart (NCT06935370) | Boehringer Ingelheim | 2025-05-20 |
| Pelacarsen Roll-over Extension Program (NCT06875973) | Novartis Pharmaceuticals | 2025-05-19 |
| A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype (NCT06522737) | SecuraBio | 2025-05-19 |
| Low Dose Nivolumab With Chemotherapy vs Standard Chemotherapy as First-Line Treatment in Advanced or Metastatic NSCLC (NCT07050043) | Dr Arvindran A/L Alaga | 2025-05-19 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes (NCT06972472) | Eli Lilly and Company | 2025-05-19 |
| Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass (NCT06702553) | Xijing Hospital | 2025-05-19 |
| Anti-vascular Endothelial Growth Factor (Anti-VEGF) Monotherapy vs Anti-VEGF Followed by Subthreshold Micropulse Laser for Treating Severe Diabetic Macular Oedema When the Central Retina Goes <400 Microns (NCT06985706) | Belfast Health and Social Care Trust | 2025-05-19 |
| A Study of Changes to Prostate Procedures (NCT06986083) | Memorial Sloan Kettering Cancer Center | 2025-05-19 |
| Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation (NCT06830798) | Alexion Pharmaceuticals, Inc. | 2025-05-19 |
| Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension) (NCT06711887) | Novartis Pharmaceuticals | 2025-05-19 |
| Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and Cataract Removal (NCT06997874) | Queen's University, Belfast | 2025-05-16 |
| 64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer (NCT06970847) | Clarity Pharmaceuticals Ltd | 2025-05-16 |
| Efficacy and Safety Study of QLM3003 Ointment in Participants With Mild or Moderate Atopic Dermatitis (NCT06880276) | Qilu Pharmaceutical Co., Ltd. | 2025-05-16 |
| Prophylactic or Preemptive Entecavir in Patients With Gastrointestinal Cancer Who Are Inactive Hepatitis B Carriers (NCT06966232) | Sun Yat-sen University | 2025-05-15 |
| Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2) (NCT06960577) | AstraZeneca | 2025-05-15 |
| A Study of BL-M07D1 Versus Investigator's Choice of Chemotherapy in Patients With HER2-low Recurrent/Metastatic Breast Cancer (NCT06957886) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-05-15 |
| A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes (NCT06993792) | Eli Lilly and Company | 2025-05-15 |
| Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma (NCT06949033) | Zuoyi Jiao | 2025-05-15 |
| Vebreltinib Plus PLB1004 Versus Platinum-based Doublet Chemotherapy in Patients With EGFRm, MET+, Locally Advanced or Metastatic NSCLC Following EGFR-TKI Failure (NCT06970782) | Avistone Biotechnology Co., Ltd. | 2025-05-15 |
| A Study of Disitamab Vedotin Combined With Tislelizumab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in HER2-Low Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (NCT06944496) | RemeGen Co., Ltd. | 2025-05-15 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related Comorbidity (NCT06972459) | Eli Lilly and Company | 2025-05-15 |
| Drug- Eluting Stent for Symptomatic Intracranial Arterial Stenosis (NCT07197970) | Beijing Tiantan Hospital | 2025-05-15 |
| A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age (NCT06806137) | GlaxoSmithKline | 2025-05-15 |
| Optimizing Reperfusion to Improve Outcomes and Neurologic Function (NCT06990867) | Corxel Pharmaceuticals | 2025-05-15 |
| A Study of YZJ-4729 Tartrate Injection for the Treatment of Pain After Abdominal Surgery (NCT06890533) | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | 2025-05-14 |
| Randomized Withdrawal Study in Patients With Schizophrenia (NCT06961968) | Vanda Pharmaceuticals | 2025-05-14 |
| Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC) (NCT06822426) | CorMedix Therapeutics | 2025-05-14 |
| Efficacy and Safety of Etoricoxib/Betamethasone Combination in Acute Bursitis, Tendinitis and Synovitis (NCT07328022) | Laboratorios Silanes S.A. de C.V. | 2025-05-14 |
| Contribution of Contrast Enhanced Ultrasound for Diagnosis of Adnexal Torsion (NCT06677554) | Central Hospital, Nancy, France | 2025-05-14 |
| A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001) (NCT06925737) | Merck Sharp & Dohme LLC | 2025-05-13 |
| Dalargin for Prevention of Organ Disfunction in High-Risk Abdominal Surgery (NCT07404358) | Botkin Hospital | 2025-05-13 |
| Effects of Ketone Supplement and Alcohol on Brain Metabolism (NCT06815237) | University of Pennsylvania | 2025-05-13 |
| Efficacy and Safety of HSK39297 in Anti-C5 Treated PNH Patients With Anemia (NCT07052838) | Haisco Pharmaceutical Group Co., Ltd. | 2025-05-12 |
| A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight (NCT06962280) | Eli Lilly and Company | 2025-05-12 |
| Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar (NCT06923592) | London School of Hygiene and Tropical Medicine | 2025-05-12 |
| Clinical Trial of the S. Flexneri-S. Sonnei Bivalent Conjugate Vaccine (NCT06838195) | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | 2025-05-12 |
| Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant (NCT06563895) | Eidos Therapeutics, a BridgeBio company | 2025-05-12 |
| A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease (NCT06819891) | Hoffmann-La Roche | 2025-05-12 |
| Fucoidan(Seaweed) Based Gel Around Immediate Implants (NCT07736287) | Krishnadevaraya College of Dental Sciences & Hospital | 2025-05-11 |
| Efficacy of Tofacitinib, Methotrexate Combination Therapy Versus Upadacitinib, Methotrexate Combination Therapy in Moderate to Severe Rheumatoid Arthritis (NCT07008846) | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 2025-05-10 |
| Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste (NCT06956599) | Colgate Palmolive | 2025-05-10 |
| Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula (NCT06807437) | SWOG Cancer Research Network | 2025-05-09 |
| ICP-332 in Subjects With Non-segmental Vitiligo (NCT07047612) | Beijing InnoCare Pharma Tech Co., Ltd. | 2025-05-09 |
| A Study Comparing IBI362 vs Semaglutide in Chinese Overweight or Obese Adults With Metabolic Dysfunction-associated Fatty Liver Disease （MAFLD） (NCT06884293) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-05-09 |