| A 52-week International, Multicenter Trial With a Long -Term Extension to Evaluate Saxagliptin With Dapagliflozin in Combination With Metformin Compared to Glimepiride in Combination With Metformin in Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone (NCT02419612) | AstraZeneca | 2015-08-14 |
| Physical Activity and Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Advanced Cancer (NCT02491632) | M.D. Anderson Cancer Center | 2015-08-13 |
| 221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease (NCT02477800) | Biogen | 2015-08-13 |
| Effect of BG00012 on Lymphocyte Subsets and Immunoglobulins in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS). (NCT02525874) | Biogen | 2015-08-11 |
| Long-Term Safety of IDP-118 Lotion in the Treatment of Plaque Psoriasis (NCT02462083) | Bausch Health Americas, Inc. | 2015-08-11 |
| Study to Evaluate the Analgesic Efficacy and Safety of Hydrocodone Bitartrate/Acetaminophen Immediate-Release Tablets in Participants With Moderate to Severe Pain Following Bunionectomy (NCT02487108) | Teva Branded Pharmaceutical Products R&D, Inc. | 2015-08-11 |
| Safety and Efficacy of IDP-118 in the Treatment of Plaque Psoriasis (NCT02462070) | Bausch Health Americas, Inc. | 2015-08-11 |
| Study to Assess the Safety and Tolerability of PT010, PT009 and PT003 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (NCT02536508) | Pearl Therapeutics, Inc. | 2015-08-10 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (NCT02417064) | Janssen Research & Development, LLC | 2015-08-10 |
| A Randomized, Double-Blind, Parallel-Group, 24-Week, Chronic-Dosing, Multi-Center Study to Assess the Efficacy and Safety of PT010, PT003, and PT009 Compared With Symbicort® Turbuhaler® (Kronos) (NCT02497001) | Pearl Therapeutics, Inc. | 2015-08-10 |
| Safety and Efficacy Study of BCD-066 Compared to Aranesp® for Anemia Treatment in Chronic Kidney Disease Patients (NCT02506868) | Biocad | 2015-08-08 |
| Versartis Trial in Pre-pubertal Japanese Children With Growth Hormone Deficiency (GHD) to Assess Long-Acting Growth Hormone (Somavaratan, VRS-317) (NCT02413138) | Versartis Inc. | 2015-08-08 |
| A Phase 3, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 3, Multicenter, Open-label, Long-term Study of SYR-472 (25 mg) in Patients With Type 2 Diabetes Mellitus Complicated by Severe Renal Impairment or End-stage Renal Disease (NCT02512068) | Takeda | 2015-08-07 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (NCT02418585) | Janssen Research & Development, LLC | 2015-08-07 |
| Lymph Node 14v Dissection in Clinical Stage T3N+, T4N+ of Gastric Cancer (NCT03264807) | National Cancer Center, Korea | 2015-08-06 |
| Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors (NCT02375204) | Alliance for Clinical Trials in Oncology | 2015-08-06 |
| Efficacy Study Comparing Compounded Topical Pain Creams vs. Placebo for Treating Pain Symptoms (NCT02497066) | Walter Reed National Military Medical Center | 2015-08-05 |
| An Investigational Immuno-therapy Trial of Nivolumab, or Nivolumab Plus Ipilimumab, or Nivolumab Plus Platinum-doublet Chemotherapy, Compared to Platinum Doublet Chemotherapy in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC) (NCT02477826) | Bristol-Myers Squibb | 2015-08-05 |
| A 3-Month Open-Label Safety and Efficacy Study of TNX-102 SL Tablets in Fibromyalgia Patients (NCT02589275) | Tonix Pharmaceuticals, Inc. | 2015-08-04 |
| Aprepitant Triple Therapy for the Prevention of CINV in Nondrinking and Young Women Who Received Moderately Emetogenic Chemotherapy (NCT03674294) | Sun Yat-sen University | 2015-08-04 |
| An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy (NCT02472145) | Janssen Research & Development, LLC | 2015-08-04 |
| Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures (NCT02408549) | UCB BIOSCIENCES, Inc. | 2015-08-03 |
| Copanlisib and Rituximab in Relapsed Indolent B-cell Non-Hodgkin's Lymphoma (iNHL) (NCT02367040) | Bayer | 2015-08-03 |
| Effect of Probiotic on Constipation (NCT03100851) | China Agricultural University | 2015-08-02 |
| Trial of Prophylactic Tamsulosin for Postoperative Urinary Retention in Primary Total Hip and Knee Arthroplasty Patients (NCT02518971) | University of Michigan | 2015-08-01 |
| Ibalizumab Plus Optimized Background Regimen in Patient With Multi-Drug Resistant HIV (NCT02475629) | TaiMed Biologics Inc. | 2015-08-01 |
| Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Volunteers (NCT02526667) | Medline Industries | 2015-08-01 |
| Platelet Reactivity in Acute Non-disabling Cerebrovascular Events (NCT02506140) | Beijing Tiantan Hospital | 2015-08-01 |
| A Study Comparing Different Dosing Regimens of Ixekizumab (LY2439821) in Participants With Moderate to Severe Plaque Psoriasis (NCT02513550) | Eli Lilly and Company | 2015-08-01 |
| NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee Joint (NCT02967302) | Hildrun Haibel | 2015-08-01 |
| Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Prior to First Dose of VIVITROL® (Naltrexone for Extended-Release Injectable Suspension) (NCT02537574) | Alkermes, Inc. | 2015-08-01 |
| Pharmacokinetics and Safety of rFVIIIFc Manufactured at 15,000 L (15K) Scale (NCT02502149) | Bioverativ Therapeutics Inc. | 2015-08-01 |
| Long-term Safety Study of Glycopyrronium in Subjects With Primary Axillary Hyperhidrosis (NCT02553798) | Journey Medical Corporation | 2015-08-01 |
| Bioequivalence Study for Benzyl Alcohol Lotion 5%. (NCT02624843) | Akorn, Inc. | 2015-08-01 |
| Efficacy of Oral Progesterone and Vaginal Progesterone After Tocolytic Therapy in Threatened Preterm Labor (NCT02989519) | Sanpasitthiprasong Hospital | 2015-08-01 |
| DC-CIK Immunotherapy Plus Chemotherapy vs Chemotherapy Alone in the Adjuvant Treatment of Stage III Colorectal Cancer (NCT02415699) | Sixth Affiliated Hospital, Sun Yat-sen University | 2015-08-01 |
| High-dose Selenium Supplementation in Patients With Left Ventricular Assist (NCT02530788) | RWTH Aachen University | 2015-08-01 |
| Study of Glycopyrronium in Subjects With Axillary Hyperhidrosis (NCT02530294) | Journey Medical Corporation | 2015-08-01 |
| Ticagrelor in Patients With ST Elevation Myocardial Infarction Treated With Pharmacological Thrombolysis (NCT02298088) | Hospital do Coracao | 2015-08-01 |
| Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus (NCT02229240) | GlaxoSmithKline | 2015-08-01 |
| Infra-orbital Nerve Block for Post Operative Analgesia in Children Undergoing Cleft Lip Surgery. (NCT02514980) | Assiut University | 2015-08-01 |
| Metformin/Atorvastatin Combination Therapy in Subjects With Type II Diabetes and Dyslipidemia (Phase 3) (NCT02947620) | Daewoong Pharmaceutical Co. LTD. | 2015-08-01 |
| Efficacy and Safety of SANGUINATE™ for Reduction of Delayed Graft Function in Patients Receiving a Kidney Transplant (NCT02490202) | Prolong Pharmaceuticals | 2015-08-01 |
| Pegfilgrastim-gema Compared to Pegfilgrastim-roche for Prevention of Induced Neutropenia in Breast Cancer Patients. (NCT03404752) | Gema Biotech S.A. | 2015-08-01 |
| Aprepitant Versus Gabapentin Prophylaxis for Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgeries (NCT02525848) | Assiut University | 2015-08-01 |
| Essentiale® Paste in Patients With Gastrointestinal Symptoms in Acute or Chronic Liver Diseases (NCT02517385) | Sanofi | 2015-08-01 |
| To Study Generic Diclofenac Sodium Topical Gel 1% in the Treatment of Osteoarthritis of the Knee (Degenerative Joint Disease Presented as Joint Pain, Stiffness, Swelling and Restricted Motion). (NCT02596451) | Glenmark Pharmaceuticals Ltd. India | 2015-08-01 |
| Clinical Trial to Evaluate the Efficacy of Metadoxine as a Therapy for Patients With Non-alcoholic Steatohepatitis (NCT02541045) | Hospital General de Mexico | 2015-08-01 |
| Trial of Vemurafenib and Cobimetinib in Patients With Advanced BRAFV600 Mutant Melanoma (NCT02427893) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2015-08-01 |
| Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia (NCT02484248) | Craig A. Friesen, MD | 2015-08-01 |
| A Multicenter Trial to Assess the MIcrovascular Integrity and Left Ventricular Function Recovery After Clopidogrel or TicagrelOr Administration, in Patients With STEMI Treated With Thrombolysis - The 'MIRTOS' Study (NCT02429271) | Hellenic Cardiovascular Research Society | 2015-08-01 |
| Prevention of Post-operative Urinary Retention (NCT02486653) | University of Wisconsin, Madison | 2015-08-01 |
| A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation (NCT02516410) | Vertex Pharmaceuticals Incorporated | 2015-08-01 |
| CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY) (NCT02369978) | Universidad Autónoma de Bucaramanga | 2015-08-01 |
| Cortical Metrics in Intervention Trials With Autism Spectrum Disorders (NCT02212275) | Duke University | 2015-08-01 |
| The Effects of Nifedipine and Metoprolol on Blood Pressure Variability in Northern Chinese (NCT02513927) | First Affiliated Hospital of Harbin Medical University | 2015-08-01 |
| Focal Electrically-Administered Seizure Therapy (FEAST) Studies at Two Enrolling Sites to Further Test and Refine the Treatment (NCT02535572) | Medical University of South Carolina | 2015-08-01 |
| ENDOTHELION Study Group: Effect of Bosentan in NAION Patients (NCT02377271) | University Hospital, Grenoble | 2015-08-01 |
| Dapagliflozin As Additional Treatment To Liraglutide And Insulin In Patients With Type 1 Diabetes (NCT02518945) | University at Buffalo | 2015-08-01 |
| Osimertinib or Docetaxel-bevacizumab as Third-line Treatment in EGFR T790M Mutated Non-Small Cell Lung Cancer (NCT02959749) | Qingdao Central Hospital | 2015-08-01 |
| Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility (NCT02432209) | Yale University | 2015-08-01 |
| A Phase 3 Pharmacokinetic Study of TAK-536 (Azilsartan) in Pediatric Patients 6 to Less Than 16 Years With Hypertension (NCT02451150) | Takeda | 2015-08-01 |
| A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Participants With Cystic Fibrosis Who Have an F508del-CFTR Mutation (NCT02565914) | Vertex Pharmaceuticals Incorporated | 2015-08-01 |
| Assessing Repeat Fit Testing for CRC (NCT03248661) | Richard Crosby | 2015-08-01 |
| Increasing Medical Male Circumcision Uptake (NCT02511548) | Progressus | 2015-08-01 |
| Peg Interferon α-2b for Relapsed Hematological Malignancies After Allo-HSCT (NCT02634294) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2015-08-01 |
| Atorvastatin in the Recipient's Kidney Graft From a Living Donor (NCT02522117) | Instituto Mexicano del Seguro Social | 2015-08-01 |
| Estimate the Efficacy of HD6610 Granule for Oxaliplatin-induced Peripheral Neuropathy (NCT02590367) | Jiangsu Province Hospital of Traditional Chinese Medicine | 2015-08-01 |
| A Phase 3 Evaluation of Daclatasvir and Asunaprevir in Treatment-naive Subjects With Chronic Hepatitis C Genotype 1b Infection (NCT02496078) | Bristol-Myers Squibb | 2015-08-01 |
| Resveratrol for the Treatment of Non Alcoholic Fatty Liver Disease and Insulin Resistance in Overweight Adolescents (NCT02216552) | University of Manitoba | 2015-08-01 |
| A Phase III Trial of Pertuzumab Retreatment in Previously Pertuzumab Treated Her2-Positive Advanced Breast Cancer (NCT02514681) | Japan Breast Cancer Research Group | 2015-08-01 |
| Comparison of Two Automated Mononuclear Collection Systems in Patients Undergoing Extracorporeal Photochemotherapy. A Cross-over Equivalence Study. (MNC_CMNC) (NCT02490163) | Fondazione IRCCS Policlinico San Matteo di Pavia | 2015-08-01 |
| Effect of Danazol on Endometrial αvβ3 Integrin Expression in Patients With Unexplained Recurrent Implantation Failure (NCT03563664) | Ain Shams University | 2015-08-01 |
| The Effects of Cognitive Behavioral Therapy and Transcranial Current Stimulation (tDCS) on Chronic Lower Back Pain (NCT02483468) | Medical University of South Carolina | 2015-08-01 |
| A Prospective Multi-center Phase III Randomized Controlled Trial (NCT02607592) | Sun Yat-sen University | 2015-08-01 |
| To Study Generic Tacrolimus Ointment, 0.1% in the Treatment of Moderate to Severe Atopic Dermatitis (Inflammation of Skin: Itchy, Red, Swollen, and Cracked Skin) (NCT02601703) | Glenmark Pharmaceuticals Ltd. India | 2015-08-01 |
| The Clinical Trial of Acupuncture Pre-treatment on PCOS (NCT02491320) | The First Affiliated Hospital of Guangzhou Medical University | 2015-08-01 |
| 2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients (NCT02490631) | Vanderbilt University | 2015-08-01 |
| Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy (NCT02733952) | Ain Shams Maternity Hospital | 2015-08-01 |
| Sitagliptin Therapy and Kinetics of Inflammatory Markers (NCT02536248) | Laval University | 2015-08-01 |
| Strategies to Reduce Injuries and Develop Confidence in Elders (NCT02475850) | Brigham and Women's Hospital | 2015-08-01 |
| Comparison of CHS-1420 Versus Humira in Subjects With Chronic Plaque Psoriasis (NCT02489227) | Coherus Oncology, Inc. | 2015-08-01 |
| Phase 3 Study of Efficacy and Safety of the XaraColl® Bupivacaine Implant After Hernioplasty (NCT02523599) | Innocoll | 2015-08-01 |
| The RCT of Acupuncture on PCOS Combined With IR (NCT02491333) | The First Affiliated Hospital of Guangzhou Medical University | 2015-08-01 |
| The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients (NCT02496780) | University of Minnesota | 2015-08-01 |
| PALbociclib CoLlaborative Adjuvant Study (NCT02513394) | Alliance Foundation Trials, LLC. | 2015-08-01 |
| Coronally Advanced Flap With Connective Tissue Graft and PRF for Recession Coverage (NCT03023995) | Dr. D. Y. Patil Dental College & Hospital | 2015-08-01 |
| The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients (NCT01762644) | Perle Bioscience, Inc. | 2015-08-01 |
| The Effect of Post Ablation Medroxyprogesterone Acetate on Endometrial Amenorrhea Rates (NCT02449161) | Guy Waddell | 2015-08-01 |
| Evaluation of Therapeutic Efficacy in Use of Chamomilla Gel, Chamomilla Infuse and Urea in Radiodermatitis (NCT02251392) | University of Brasilia | 2015-08-01 |
| A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE) (NCT02511405) | Vascular Biogenics Ltd. operating as VBL Therapeutics | 2015-08-01 |
| Standard Care Versus Triventricular Pacing in Heart Failure (NCT02529410) | Guy's and St Thomas' NHS Foundation Trust | 2015-08-01 |
| Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection (NCT02523443) | Memorial Sloan Kettering Cancer Center | 2015-08-01 |
| A Trial On 4 Cycles Of Neoadjuvant Chemotherapy Plus Concurrent Chemoradiation In N2-3 Nasopharyngeal Carcinoma (NCT02512315) | Sun Yat-sen University | 2015-08-01 |
| Simultaneous Modulated Accelerated Boost Versus Standard Dose Radiotherapy in Esophageal Cancer (NCT02556762) | Chuangzhen Chen | 2015-08-01 |
| Immunogenicity and Safety of Liquid Bivalent Oral Poliomyelitis Vaccine (NCT02434770) | PATH | 2015-08-01 |
| Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor (NCT02544451) | Vertex Pharmaceuticals Incorporated | 2015-08-01 |
| Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 1301) (NCT02345850) | National Heart, Lung, and Blood Institute (NHLBI) | 2015-08-01 |
| A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC) (NCT02453308) | University of Oxford | 2015-08-01 |
| A Study of Vonapanitase (PRT-201) Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-2) (NCT02414841) | Proteon Therapeutics | 2015-08-01 |