| Randomized, Open-Label, Multicenter, Controlled, Pivotal Study to Assess Safety and Efficacy of ELAD in Subjects w/ AILD (NCT02612428) | Vital Therapies, Inc. | 2016-01-01 |
| Outcomes of Opioid Addicted Prisoners With Extended-Release Injectable Naltrexone (NCT02617628) | University of Pennsylvania | 2016-01-01 |
| A Safety and Efficacy Study of Tavilermide (MIM-D3) Ophthalmic Solution for the Treatment of Dry Eye Disease (NCT02665234) | Mimetogen Pharmaceuticals USA, Inc. | 2016-01-01 |
| Behavioral Economic Incentives to Improve Glycemic Control Among Adolescents and Young Adults (NCT02568501) | University of Pennsylvania | 2016-01-01 |
| Cost-utility and Biological Underpinnings of MBSR in Fibromyalgia Syndrome (NCT02561416) | Fundació Sant Joan de Déu | 2016-01-01 |
| A Clinical Study to Investigate the Long-term Use of Lacosamide as Monotherapy in Subjects Who Completed Study SP0994 (NCT02582866) | UCB Biopharma S.P.R.L. | 2016-01-01 |
| Determine the Efficacy of TT-173. Reducing the the Total Blood Loss Associated With Total Knee Arthroplasty (HESTAT) (NCT02687399) | Thrombotargets Europe S.L | 2016-01-01 |
| Safety and Immunogenicity Study of Live Attenuated Mumps Vaccines in Healthy Infants (NCT02692599) | Sinovac (Dalian) Vaccine Technology Co., Ltd. | 2016-01-01 |
| A Study Comparing Ponatinib and Nilotinib in Participants With Chronic Myeloid Leukemia (NCT02627677) | Ariad Pharmaceuticals | 2015-12-31 |
| Efficacy of Iron Bisglycinate in Treatment of Iron Deficiency Anemia in Pregnant Women (NCT03378791) | Hatem AbuHashim | 2015-12-31 |
| A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) (NCT02545283) | Hoffmann-La Roche | 2015-12-30 |
| An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation (NCT02577406) | Celgene | 2015-12-30 |
| International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device (NCT02656329) | GE Healthcare | 2015-12-30 |
| RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity (NCT02375971) | Novartis Pharmaceuticals | 2015-12-30 |
| Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers (NCT02785952) | SWOG Cancer Research Network | 2015-12-29 |
| A Multicenter Randomized 52 Week Treatment Double-blind, Triple Dummy Parallel Group Study to Assess the Efficacy and Safety of QMF149 Compared to Mometasone Furoate in Participants With Asthma (NCT02554786) | Novartis Pharmaceuticals | 2015-12-29 |
| Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300) (NCT02625623) | EMD Serono Research & Development Institute, Inc. | 2015-12-28 |
| The BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial Lipodystrophy (NCT02527343) | Akcea Therapeutics | 2015-12-28 |
| Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions (NCT02059499) | AIDS Malignancy Consortium | 2015-12-28 |
| Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia Study (NCT02593773) | Amgen | 2015-12-25 |
| Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100) (NCT02625610) | EMD Serono Research & Development Institute, Inc. | 2015-12-24 |
| The Effect of Lovastatin Gel in the Treatment of Chronic Periodontitis (NCT03178526) | Islamic Azad University, Sanandaj | 2015-12-24 |
| A Study to Assess the Effects of PT003 and Placebo MDI on Specific Image Based Airway Volumes and Resistance in Subjects With Moderate to Severe COPD (NCT02643082) | Pearl Therapeutics, Inc. | 2015-12-23 |
| Changes in Body Composition After EPA Supplementation in Head and Neck Patients (NCT02715596) | Institut Català d'Oncologia | 2015-12-23 |
| Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease (NCT04958642) | Mandos LLC | 2015-12-23 |
| Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Patients Having Acute Respiratory Distress Syndrome (ARDS) (NCT02622724) | Faron Pharmaceuticals Ltd | 2015-12-23 |
| The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome (NCT02658175) | Akcea Therapeutics | 2015-12-23 |
| Study to Evaluate the Efficacy of MONotherapy of TiviCAY® Versus a Triple Therapy in HIV-1-infected Patients (NCT02596334) | Centre Hospitalier Régional d'Orléans | 2015-12-23 |
| Safety and Efficacy of SOF/VEL/VOX FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor (NCT02639247) | Gilead Sciences | 2015-12-23 |
| Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome (NCT02521493) | Children's Oncology Group | 2015-12-23 |
| Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis (NCT02639338) | Gilead Sciences | 2015-12-23 |
| Long-Term Extension Study of Ofatumumab in Subjects With Pemphigus Vulgaris (NCT02613910) | GlaxoSmithKline | 2015-12-23 |
| Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH) (NCT02537431) | Kyowa Kirin, Inc. | 2015-12-23 |
| Switching From a Tenofovir Disoproxil Fumarate (TDF) Containing Regimen to Elvitegravir/Cobicistat/Emtricitabine/ Tenofovir Alafenamide (E/C/F/TAF) Fixed-Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Infected Adults Aged ≥ 60 Years (NCT02616783) | Gilead Sciences | 2015-12-22 |
| Empagliflozin as Adjunctive to Insulin Therapy Over 26 Weeks in Patients With T1DM (EASE-3) (NCT02580591) | Boehringer Ingelheim | 2015-12-22 |
| Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Limited Stage or Extensive Stage Small Cell Lung Cancer (NCT02635009) | NRG Oncology | 2015-12-22 |
| Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (NCT02654054) | AbbVie | 2015-12-22 |
| Peanut Allergy Oral Immunotherapy Study of AR101 for Desensitization in Children and Adults (PALISADE) (NCT02635776) | Aimmune Therapeutics, Inc. | 2015-12-22 |
| Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Adults With Chronic HCV and HBV Coinfection (NCT02613871) | Gilead Sciences | 2015-12-22 |
| Zinc-L-Carnosine Prevents Dysphagia in Breast Cancer Patients Undergoing Adjuvant Radiotherapy (NCT03997188) | Cynthia Aristei | 2015-12-21 |
| A Study Of Avelumab Alone Or In Combination With Pegylated Liposomal Doxorubicin Versus Pegylated Liposomal Doxorubicin Alone In Patients With Platinum Resistant/Refractory Ovarian Cancer (JAVELIN Ovarian 200) (NCT02580058) | Pfizer | 2015-12-21 |
| Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment (NCT02585895) | Amgen | 2015-12-21 |
| Nivolumab Combined With Ipilimumab Followed by Nivolumab Monotherapy as First-Line Treatment for Patients With Advanced Melanoma (NCT02599402) | Bristol-Myers Squibb | 2015-12-20 |
| Prevention of Cardiovascular Disease With Polypill Among Pars Cohort Participants (NCT03459560) | Tehran University of Medical Sciences | 2015-12-20 |
| Efficacy and Safety of the Biosimilar Ranibizumab FYB201 in Comparison to Lucentis in Patients With Neovascular Age-related Macular Degeneration (NCT02611778) | Bioeq GmbH | 2015-12-19 |
| Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency (NCT02004691) | Genzyme, a Sanofi Company | 2015-12-18 |
| Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis (NCT02611830) | Takeda | 2015-12-18 |
| A Study to Evaluate the Safety of Long Term Treatment With Teriflunomide 14 mg Once Daily in Patients With a First Clinical Episode Suggestive of Multiple Sclerosis in a Long-term Extension Period (NCT02587195) | Centre Hospitalier Universitaire de Nice | 2015-12-18 |
| Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study (NCT02576067) | Icahn School of Medicine at Mount Sinai | 2015-12-18 |
| Use of Ultiva ® Associated With Xylocaine ® in the Procedures of Feticide (NCT02597699) | University Hospital, Montpellier | 2015-12-18 |
| Trial to Evaluate the Improvement of Chronic Low-grade AEs in Patients With Ph+ CML With Optimal Response to Imatinib When Switched to Nilotinib (NCT02115386) | Novartis Pharmaceuticals | 2015-12-17 |
| Study to Evaluate Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) in Virologically-Suppressed HIV-1 Infected Adults Harboring the Archived Isolated NRTI Resistance Mutation M184V/M184I (NCT02616029) | Gilead Sciences | 2015-12-17 |
| A Study Comparing Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on a Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response to csDMARDs Alone (NCT02675426) | AbbVie | 2015-12-17 |
| Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease (NCT02433158) | GlycoMimetics Incorporated | 2015-12-16 |
| A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012) (NCT02630706) | Merck Sharp & Dohme LLC | 2015-12-16 |
| Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes (NCT02556203) | Bayer | 2015-12-16 |
| An Efficacy and Safety of Guselkumab in Participants With Palmoplantar Pustulosis (NCT02641730) | Janssen Pharmaceutical K.K. | 2015-12-15 |
| Pilot Study Evaluating the Efficacy of Certolizumab Pegol for Interstitial Cystitis (NCT02497976) | ICStudy, LLC | 2015-12-15 |
| Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) in Adults ≥ 65 Years of Age With and Without Zostavax® Vaccination at Least 5 Years Earlier (NCT02581410) | GlaxoSmithKline | 2015-12-15 |
| Safety and Efficacy of Modified Folfirinox Versus Gemcis in Bile Duct Tumours (NCT02591030) | Centre Hospitalier Universitaire de Saint Etienne | 2015-12-15 |
| Study of ADXS11-001 in Participants With High Risk Locally Advanced Cervical Cancer (NCT02853604) | Advaxis, Inc. | 2015-12-15 |
| Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration (NCT02686658) | IVERIC bio, Inc. | 2015-12-15 |
| A Study of HyQvia and Gammagard Liquid (Kiovig) in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) (NCT02549170) | Baxalta now part of Shire | 2015-12-15 |
| TREg Activation in the Treatment of the PELADE (Alopecia Areata) (NCT02557074) | Centre Hospitalier Universitaire de Nice | 2015-12-15 |
| Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression (NCT02600494) | Intra-Cellular Therapies, Inc. | 2015-12-15 |
| Study of Nivolumab in Unresectable Advanced or Recurrent Esophageal Cancer (NCT02569242) | Ono Pharmaceutical Co., Ltd. | 2015-12-14 |
| Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of E/C/F/TAF Fixed Dose Combination (FDC) in HIV-1 Infected Adults on Chronic Hemodialysis (NCT02600819) | Gilead Sciences | 2015-12-14 |
| Study of Efficacy and Safety of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment. (NCT02555683) | Novartis Pharmaceuticals | 2015-12-11 |
| Efficacy Study of Nivolumab Compared to Docetaxel in Subjects Previously Treated With Advanced or Metastatic Non Small Cell Lung Cancer (NCT02613507) | Bristol-Myers Squibb | 2015-12-11 |
| A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1 (NCT02634307) | Biogen | 2015-12-10 |
| Intravenous Immunoglobulin for Unverricht-Lundborg Disease. (NCT03351569) | Azienda Socio Sanitaria Territoriale di Mantova | 2015-12-09 |
| A Phase III Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer (NCT02691299) | Hutchison Medipharma Limited | 2015-12-09 |
| Study to Compare the Efficacy and Safety of QVM149 With QMF149 in Patients With Asthma (NCT02571777) | Novartis Pharmaceuticals | 2015-12-08 |
| Efficacy and Safety Study of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn's Disease (NCT02596893) | Celgene | 2015-12-08 |
| PROphylaxis in NOn Major Orthopaedic Surgery (NCT02401594) | Centre Hospitalier Universitaire de Saint Etienne | 2015-12-08 |
| Phase III Study of Surufatinib in Treating Advanced Pancreatic Neuroendocrine Tumors (NCT02589821) | Hutchison Medipharma Limited | 2015-12-07 |
| An Investigational Immuno-therapy Study of Nivolumab Compared to Sorafenib as a First Treatment in Patients With Advanced Hepatocellular Carcinoma (NCT02576509) | Bristol-Myers Squibb | 2015-12-07 |
| A Study to Evaluate the Safety and Efficacy of Domperidone in Pediatric Participants With Nausea and Vomiting Due to Acute Gastroenteritis (NCT02699385) | Janssen-Cilag International NV | 2015-12-07 |
| A Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determine if Reduction in Dysphagia is Achieved (NCT02605837) | Shire | 2015-12-07 |
| A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIa (NCT02448680) | Laboratoire français de Fractionnement et de Biotechnologies | 2015-12-07 |
| A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 1, 2, 4, 5 or 6 Infection and Compensated Cirrhosis (NCT02642432) | AbbVie | 2015-12-07 |
| Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors (NCT02588170) | Hutchison Medipharma Limited | 2015-12-07 |
| A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study- (NCT02623738) | Santen Pharmaceutical Co., Ltd. | 2015-12-06 |
| Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis (NCT02630628) | The University of Hong Kong | 2015-12-05 |
| Sanitation, Water, and Instruction in Face-washing for Trachoma I/II (NCT02754583) | University of California, San Francisco | 2015-12-05 |
| A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (NCT02562508) | Jun Zhang | 2015-12-05 |
| Evaluation of Efficay & Safety of Galcanezumab in the Prevention of Episodic Migraine- the EVOLVE-2 Study (NCT02614196) | Eli Lilly and Company | 2015-12-04 |
| Treatment of Peri-calcification Edema in Neurocysticercosis (NCC) (NCT02945527) | Universidad Peruana Cayetano Heredia | 2015-12-04 |
| Pancreatic Duct Stenting to Prevent Postoperative Pancreatic Fistula (POPF) After Distal Pancreatectomy (NCT02573389) | Kaiser Permanente | 2015-12-04 |
| Colchicine Cardiovascular Outcomes Trial (COLCOT) (NCT02551094) | Montreal Heart Institute | 2015-12-04 |
| Estradiol Patch as add-on to Antipsychotics in Patients With Schizophrenia, Schizoaffective or Schizophreniform Disorder (NCT03848234) | Tangent Data | 2015-12-04 |
| Study of Efficacy and Safety of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment. (NCT02563067) | Novartis Pharmaceuticals | 2015-12-03 |
| Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency (NCT02558829) | AEterna Zentaris | 2015-12-03 |
| Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children (NCT02477007) | Assistance Publique - Hôpitaux de Paris | 2015-12-03 |
| Efficacy of Alicaforsen in Pouchitis Patients Who Have Failed to Respond to at Least One Course of Antibiotics (NCT02525523) | Atlantic Pharmaceuticals Ltd | 2015-12-03 |
| Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC) (NCT02584439) | University Hospital, Rouen | 2015-12-03 |
| An Extension Study of RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis (NCT02531126) | Celgene | 2015-12-02 |
| Ph3 Study To Determine Safety,Tolerability&Tumor Response Of Oraxol Compared To Taxol In Metastatic Breast Cancer (NCT02594371) | Athenex, Inc. | 2015-12-02 |
| Alvimopan as Rescue in Post op Ileus (NCT02742181) | Sharon Stein | 2015-12-02 |
| Controlled Study of Rigosertib Versus Physician's Choice of Treatment in MDS Patients After Failure of an HMA (NCT02562443) | Traws Pharma, Inc. | 2015-12-02 |