| A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome (NCT03355209) | Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc. | 2017-11-27 |
| Four Quadrants Transverse Abdominus Plane (4Q-TAP) Block With Plain and Liposomal Bupivacaine vs. Thoracic Epidermal Analgesia (TEA) in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) on an Enhanced Recovery Pathway (NCT03359811) | M.D. Anderson Cancer Center | 2017-11-27 |
| Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission (NCT03267433) | ECOG-ACRIN Cancer Research Group | 2017-11-27 |
| Lumateperone Monotherapy for the Treatment of Bipolar Depression Conducted Globally (NCT03249376) | Intra-Cellular Therapies, Inc. | 2017-11-27 |
| Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin (NCT03351478) | Lexicon Pharmaceuticals | 2017-11-27 |
| A Study of LY01008 and Bevacizumab Combined With Paclitaxel and Carboplatin for Treatment of Naïve Subjects With Metastatic or Recurrent Nonsquamous Non-small Cell Lung Cancer (NCT03533127) | Luye Pharma Group Ltd. | 2017-11-27 |
| 8-Week Atopic Dermatitis (AD) Treatment Study (NCT03386032) | Procter and Gamble | 2017-11-27 |
| Pathological Complete Response Rate in Locally Advanced Breast Cancer With FEC, EC-T, or TC as Neoadjuvant Chemotherapy (NCT03349177) | Zhiyong Yu | 2017-11-27 |
| Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis (NCT03334422) | Eli Lilly and Company | 2017-11-27 |
| Facilitating Rapid Naltrexone Initiation (NCT03345173) | New York State Psychiatric Institute | 2017-11-25 |
| A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol A (NCT03316300) | Neurotech Pharmaceuticals | 2017-11-24 |
| A Study to Evaluate the Efficacy of Tocilizumab as a Remission-Induction and Glucocorticoid-Sparing Regimen in Subjects With New-Onset Polymyalgia Rheumatica (PMR- SPARE) (NCT03263715) | Medical University of Vienna | 2017-11-24 |
| Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma (NCT03347279) | AstraZeneca | 2017-11-23 |
| Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction (NCT02901184) | Uppsala University | 2017-11-23 |
| A Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis (NCT03334396) | Eli Lilly and Company | 2017-11-23 |
| A Study of VELCADE (Bortezomib) Melphalan-Prednisone (VMP) Compared to Daratumumab in Combination With VMP (D-VMP), in Participants With Previously Untreated Multiple Myeloma Who Are Ineligible for High-Dose Therapy (Asia Pacific Region) (NCT03217812) | Janssen Research & Development, LLC | 2017-11-23 |
| Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia (NCT03236805) | Nantes University Hospital | 2017-11-23 |
| Phase II/III Study to Assess the Efficacy of Neoadjuvant Consolidation Chemotherapy in Rectal Cancer Patients. (NCT03957733) | King Abdullah Medical City | 2017-11-23 |
| Research Study Comparing Insulin Degludec to Insulin Detemir, Together With Insulin Aspart, in Pregnant Women With Type 1 Diabetes (NCT03377699) | Novo Nordisk A/S | 2017-11-22 |
| Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Wilate in Previously Treated Paediatric Patients With Severe Haemophilia A (NCT03376516) | Octapharma | 2017-11-22 |
| Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (NCT03086486) | Global Alliance for TB Drug Development | 2017-11-21 |
| A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitus With Nasal Polyps (NCT03280537) | Hoffmann-La Roche | 2017-11-21 |
| Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy? (NCT03269994) | Memorial Sloan Kettering Cancer Center | 2017-11-21 |
| Clinical Endpoint Bioequivalence Study of Test and Reference Inhalation Products in Patients With COPD With Device Robustness (NCT03137992) | Lupin, Inc. | 2017-11-21 |
| Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide (NCT03298802) | The University of Texas Medical Branch, Galveston | 2017-11-21 |
| Evaluation of SPN-812 (Viloxazine Extended-release Capsule) High Dose in Adolescents With ADHD (NCT03247556) | Supernus Pharmaceuticals, Inc. | 2017-11-20 |
| CHAMP: Study of NVK-002 in Children With Myopia (NCT03350620) | Vyluma, Inc. | 2017-11-20 |
| The Safety and Effectiveness of PEEK Interference Screws in Anterior Cruciate Ligament Reconstruction (NCT03342222) | Central South University | 2017-11-20 |
| Functional Respiratory Imaging Study (FRI) (NCT03268226) | Chiesi Farmaceutici S.p.A. | 2017-11-20 |
| A Study of Paliperidone Palmitate 6-Month Formulation (NCT03345342) | Janssen Research & Development, LLC | 2017-11-20 |
| Xylitol for Otitis Media (NCT02950311) | Duke University | 2017-11-20 |
| XELOX for 4 Months Versus 6 Months in Gastric Cancer (LOMAC) (NCT03399110) | Fudan University | 2017-11-17 |
| Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticosteroids (TCS) in Participants ≥6 to <12 Years With Severe Atopic Dermatitis (AD) (NCT03345914) | Regeneron Pharmaceuticals | 2017-11-17 |
| Entecavir to TAF Switch (NCT03489239) | Thomas Jefferson University | 2017-11-16 |
| MAGnesium Adjunction in Alcohol Withdrawal Syndrome: a Multicenter Assessment (MAGMA) (NCT03033823) | Assistance Publique - Hôpitaux de Paris | 2017-11-16 |
| ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP) (NCT03338816) | Alnylam Pharmaceuticals | 2017-11-16 |
| Western Australian Pre-exposure Prophylaxis for HIV Implementation Trial (NCT03327155) | Kirby Institute | 2017-11-16 |
| A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma (NCT03274492) | Hoffmann-La Roche | 2017-11-16 |
| Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control (NCT03351348) | Memorial Sloan Kettering Cancer Center | 2017-11-16 |
| Role of Propolis Paste in Preventing Pain After Root Canal Treatment. (NCT03723980) | Juzer Shabbir Saifee | 2017-11-16 |
| rVWF IN PROPHYLAXIS (NCT02973087) | Takeda | 2017-11-16 |
| A Study of JNJ-63723283, an Anti-programmed Death-1 Monoclonal Antibody, Administered in Combination With Daratumumab, Compared With Daratumumab Alone in Participants With Relapsed or Refractory Multiple Myeloma (NCT03357952) | Janssen Research & Development, LLC | 2017-11-16 |
| A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps (NCT03280550) | Hoffmann-La Roche | 2017-11-15 |
| Cryptococcal Antigen Screening Plus Sertraline (NCT03002012) | University of Minnesota | 2017-11-15 |
| Treatment Evaluation of Acute Stroke for Using in Regenerative Cell Elements (NCT02961504) | Healios K.K. | 2017-11-15 |
| Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES) (NCT03363841) | Scynexis, Inc. | 2017-11-15 |
| Efficacy of Quadrivalent HPV Vaccine to Prevent Relapses of Genital Warts After Initial Therapeutic Response (NCT03296397) | Assistance Publique - Hôpitaux de Paris | 2017-11-15 |
| A Study of Aripiprazole Lauroxil or Paliperidone Palmitate for the Treatment of Schizophrenia (NCT03345979) | Alkermes, Inc. | 2017-11-15 |
| Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia (NCT03389724) | Children's Cancer Hospital Egypt 57357 | 2017-11-14 |
| Efficacy Of Bovine Colostrum In The Treatment Of Severe Alcohol-Associated Hepatitis: A Randomized Controlled Trial (NCT02473341) | Dayanand Medical College and Hospital | 2017-11-14 |
| Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome (NCT02813824) | Assistance Publique - Hôpitaux de Paris | 2017-11-14 |
| Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery (NCT03363425) | University of Athens | 2017-11-14 |
| TPF+CCRT vs.CCRT+PF in High Risk Nasopharyngeal Carcinoma (NCT03306121) | Sun Yat-sen University | 2017-11-13 |
| A Safety, Tolerability and Efficacy Study of TransCon hGH in Children With Growth Hormone Deficiency (NCT03305016) | Ascendis Pharma Endocrinology Division A/S | 2017-11-13 |
| A Trial of Absorbable Medical Adhesive for Prevention of CSF Leak (NCT07768553) | Medprin Regenerative Medical Technologies Co., Ltd. | 2017-11-13 |
| Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE) (NCT03358329) | Intersect ENT | 2017-11-13 |
| A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622 (NCT03306043) | GlaxoSmithKline | 2017-11-13 |
| Antimicrobial Barrier Dressing Versus Closed-incision Negative Pressure Therapy in the Obese Primary Total Joint Arthroplasty (NCT03345771) | NYU Langone Health | 2017-11-13 |
| In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste (NCT03296072) | GlaxoSmithKline | 2017-11-13 |
| CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase3) (NCT03289702) | Medy-Tox | 2017-11-13 |
| Kypho-IORT vs. EBRT in Spinal Metastases (NCT02773966) | Universitätsmedizin Mannheim | 2017-11-12 |
| The Effect Of Ultrasound-guided Modified Pectoral Nerves Block Versus Ketamine Plus Magnesium Infusion On Analgesic Profile In Breast Cancer Surgeries (NCT04095455) | National Cancer Institute, Egypt | 2017-11-12 |
| Pharmacokinetics and Dynamics of Dexmedetomidine as Adjuvant in TAP Block (NCT03328299) | Assiut University | 2017-11-11 |
| Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer (NCT03331588) | Shanghai Pulmonary Hospital, Shanghai, China | 2017-11-10 |
| Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment (NCT02862977) | EMS | 2017-11-10 |
| Resveratrol in Knee Osteoarthritis (NCT02905799) | Assistance Publique - Hôpitaux de Paris | 2017-11-09 |
| Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer (NCT03425838) | Borstkanker Onderzoek Groep | 2017-11-09 |
| Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation (NCT03270501) | University Ghent | 2017-11-08 |
| Maximizing Outcome of Multiple Sclerosis Transplantation (NCT03342638) | Northwestern University | 2017-11-08 |
| A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine (NCT03282227) | Zosano Pharma Corporation | 2017-11-07 |
| Precision-exercise-prescription for Lung Cancer Patients Undergoing Surgery: The PEP Study (NCT03306992) | University of Utah | 2017-11-07 |
| Trial of Sacituzumab Govitecan in Participants With Refractory/Relapsed Metastatic Triple-Negative Breast Cancer (TNBC) (NCT02574455) | Gilead Sciences | 2017-11-07 |
| Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women (NCT03164564) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-11-07 |
| Botulinum Toxin for Trigeminal Neuralgia (NCT03331913) | The First Affiliated Hospital of Zhengzhou University | 2017-11-07 |
| A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma (NCT03301220) | Janssen Research & Development, LLC | 2017-11-07 |
| Efficacy and Safety of CKD-501 Added to D150 Plus D745 10mg Therapy in Patients With Type 2 Diabetes (NCT03739125) | Chong Kun Dang Pharmaceutical | 2017-11-07 |
| Trabectedin Maintenance Post 1st-line in STS (NCT02929394) | European Organisation for Research and Treatment of Cancer - EORTC | 2017-11-07 |
| Comparing Effect of Autologous Platelet-Rich Plasma Versus Hyaluronic Acid Treatment on Knee Osteoarthritis (NCT04972383) | Kaohsiung Medical University Chung-Ho Memorial Hospital | 2017-11-07 |
| Naloxegol and Opioid-induced Constipation (NCT03316859) | TriHealth Inc. | 2017-11-06 |
| Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma (NCT03342300) | Peking University People's Hospital | 2017-11-06 |
| PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM) (NCT03193333) | Laboratorios Sophia S.A de C.V. | 2017-11-06 |
| Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients (NCT03221842) | CSL Behring | 2017-11-06 |
| A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD) (NCT02932618) | Baxalta now part of Shire | 2017-11-06 |
| The Effect of Different Drugs in the Prevention of Tooth Sensitivity Caused by Tooth Bleaching Treatment. (NCT03343392) | Universidade Estadual de Ponta Grossa | 2017-11-05 |
| Phase 2B/3 Double-blinded Placebo-controlled (NCT03107377) | Evofem Inc. | 2017-11-03 |
| Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease (NCT03357471) | UCB Biopharma S.P.R.L. | 2017-11-03 |
| Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer (NCT03244384) | National Cancer Institute (NCI) | 2017-11-03 |
| Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical Studies (NCT03031938) | Pfizer | 2017-11-03 |
| Assessment of the Clinical and Ultrasound Response to Apremilast by Clinical Evaluation and by a Joint-periarticular-nail Ultrasound Index in Patients With Active Psoriatic Arthritis (NCT03191539) | Hospital Universitari Vall d'Hebron Research Institute | 2017-11-02 |
| Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes (NCT04390295) | Jiangsu HengRui Medicine Co., Ltd. | 2017-11-02 |
| Evaluation of SPN-812 (Viloxazine Extended-release Capsule) Low Dose in Adolescents With ADHD (NCT03247517) | Supernus Pharmaceuticals, Inc. | 2017-11-02 |
| REduced Dose Versus Full-dose of Direct Oral Anticoagulant After uNprOvoked Venous thromboEmbolism. (NCT03285438) | University Hospital, Brest | 2017-11-02 |
| Study to Assess the Safety and Efficacy of ONZETRA® Xsail® for the Acute Treatment of Episodic Migraine With or Without Aura in Adolescents (NCT03338920) | Currax Pharmaceuticals | 2017-11-02 |
| Longer-term Study of AR101 in Subjects Who Participated in a Prior AR101 Study (ARC008) (NCT03292484) | Aimmune Therapeutics, Inc. | 2017-11-02 |
| Topiramate and Prolonged Exposure (NCT03176953) | VA Office of Research and Development | 2017-11-01 |
| Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders (NCT03350633) | Tianjin Medical University General Hospital | 2017-11-01 |
| SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain (NCT03204331) | Myovant Sciences GmbH | 2017-11-01 |
| Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast Cancer (NCT03351062) | Chinese Anti-Cancer Association | 2017-11-01 |
| Staging Prostate Cancer With Hybrid C11-Choline PET/MR and mpMRI (NCT03404648) | Mayo Clinic | 2017-11-01 |
| Inclisiran for Subjects With ASCVD or ASCVD-Risk Equivalents and Elevated Low-density Lipoprotein Cholesterol (NCT03400800) | The Medicines Company | 2017-11-01 |