| Zilucoplan for Severe gMG Exacerbations (NCT07215949) | Miriam Freimer | 2026-01-20 |
| Comparative Evaluation of Clinical and Radiographic Treatment Outcomes of Garlic Gel and Calcium Hydroxide as an Intracanal Medicament in Nonsurgical Root Canal Treatment of Permanent Teeth. (NCT07289971) | University of Health Sciences Lahore | 2026-01-20 |
| Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease (NCT07247188) | Sanofi | 2026-01-20 |
| Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age (NCT07348692) | Sanofi | 2026-01-20 |
| A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years) (NCT06579755) | Takeda | 2026-01-20 |
| Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia (NCT07330375) | Zagazig University | 2026-01-20 |
| A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2) (NCT07359846) | Generate Biomedicines | 2026-01-20 |
| A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22) (NCT07216703) | Merck Sharp & Dohme LLC | 2026-01-19 |
| A Multicentre, Randomised, Double-blind, Placebo-parallel Controlled Phase Ⅲ Clinical Trial Evaluating the Efficacy and Safety of BXOS110 Injection in the Treatment of Acute Ischaemic Stroke Within 3 Hours of Onset. (NCT07520565) | Biocells (Beijing) Biotech Co.,Ltd | 2026-01-19 |
| Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations (NCT07195695) | Boehringer Ingelheim | 2026-01-16 |
| Vorasidenib Maintenance for IDH Mutant Astrocytoma (NCT06809322) | European Organisation for Research and Treatment of Cancer - EORTC | 2026-01-16 |
| RC48 Combined With Chemotherapy in HER2-Positive Advanced Breast Cancer Patients With Prior TOP1i-ADC Failure (NCT07366840) | Fudan University | 2026-01-16 |
| Efficacy and Safety of Anti-angiogenic Therapy With IV Bevacizumab in Patients With Symptomatic Cerebral Arteriovenous Malformations (NCT06264531) | Fondation Ophtalmologique Adolphe de Rothschild | 2026-01-16 |
| A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis (NCT07185009) | Sanofi | 2026-01-16 |
| A Study of Zovaglutide in Subjects With Overweight or Obesity (HORIZON-1) (NCT07230119) | Beijing QL Biopharmaceutical Co.,Ltd | 2026-01-16 |
| Adaptive RCT of Corticosteroids for Severe Chlamydia Psittaci Pneumonia in Adults (NCT07352865) | Qingyuan Zhan | 2026-01-15 |
| Single vs Triple Hyaluronic Acid in Knee Osteoarthritis (NCT07352540) | University of Erlangen-Nürnberg Medical School | 2026-01-15 |
| Phase III Clinical Study of HB0025 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First-Line Treatment of Advanced Squamous Non-Small Cell Lung Cancer (NCT07360132) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2026-01-15 |
| Efficacy of Intravesical Oxybutynin in Children With Neurogenic Bladder Dysfunction (NCT07027020) | Central Hospital, Nancy, France | 2026-01-15 |
| Phase III Clinical Study of HB0025 Combined With Chemotherapy Versus Tislelizumab Combined With Chemotherapy as First-Line Treatment for Advanced Nonsquamous Non-Small Cell Lung Cancer (NCT07383116) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2026-01-15 |
| A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease (NCT06996730) | Banner Health | 2026-01-15 |
| Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALL (NCT07297914) | Bambino Gesù Hospital and Research Institute | 2026-01-15 |
| A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD) (NCT07266402) | Celldex Therapeutics | 2026-01-15 |
| Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved. (NCT07276542) | The Ketamine Research Foundation | 2026-01-15 |
| Short-course Tislelizumab Combined With Chemoradiotherapy for Nasopharyngeal Carcinoma (NCT07373990) | Sun Yat-sen University | 2026-01-15 |
| Randomised Study Within a Review (SWAR) to Compare Communication of the Findings of Systematic Reviews to the Public by Plain Language Summary or Video Abstract (NCT07333924) | Queen's University, Belfast | 2026-01-15 |
| Baclofen for Improving Benzodiazepine Titration in Benzodiazepine Dependence (NCT05935553) | Hospices Civils de Lyon | 2026-01-15 |
| Functional Lung Avoidance Planning Guided by Lung Perfusion PET/CT Versus Anatomical Planning for Lung Stereotactic Body Radiotherapy (NCT07289646) | University Hospital, Brest | 2026-01-15 |
| Study to Confirm the AuthenTicity of Point of Care Urine samplEs Using Oral fluoreScein Sodium in adulTs With substancE Use Disorder (ATTESTED) (NCT07356349) | UpTru Inc. | 2026-01-15 |
| Adaptive RCT of Corticosteroids for Severe Influenza Pneumonia in Adults (NCT07351500) | Qingyuan Zhan | 2026-01-15 |
| A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4) (NCT07298330) | Mirum Pharmaceuticals, Inc. | 2026-01-14 |
| Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design (NCT07398417) | Axsome Therapeutics, Inc. | 2026-01-14 |
| Efficacy and Safety of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (STELLAR) (NCT07317934) | Innostellar Biotherapeutics Co.,Ltd | 2026-01-14 |
| A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma (NCT06980480) | Takeda | 2026-01-14 |
| Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy (NCT07186192) | City of Hope Medical Center | 2026-01-14 |
| Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis (NCT07325292) | Sanofi | 2026-01-14 |
| A Study of Telitacicept in Patients With Ocular Myasthenia Gravis (OMG) (NCT07249632) | RemeGen Co., Ltd. | 2026-01-13 |
| A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults (NCT07382167) | Ardelyx | 2026-01-13 |
| A Trial to Evaluate the Efficacy and Safety of SHR-1918 in Patients With Hyperlipidemia (NCT07230730) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2026-01-13 |
| A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis (NCT07355062) | Renibus Therapeutics, Inc. | 2026-01-13 |
| A Clinical Study to Evaluate the Efficacy and Safety of D-2570 in the Treatment of Moderate to Severe Plaque Psoriasis (NCT07326813) | InventisBio Co., Ltd | 2026-01-12 |
| A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults (NCT07222137) | Eli Lilly and Company | 2026-01-12 |
| Intravenous Tirofiban After Bridging Therapy for Acute Stroke With Atherosclerotic Large Artery Occlusion (NCT07335107) | Beijing Tiantan Hospital | 2026-01-12 |
| A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy (NCT07188558) | Lyell Immunopharma, Inc. | 2026-01-12 |
| Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes (NCT07284901) | Kailera | 2026-01-12 |
| A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age (NCT07365826) | Vaxcyte, Inc. | 2026-01-12 |
| Methadone in THA for Post-op Pain and Opioid Reduction (NCT07227064) | Medical University of South Carolina | 2026-01-12 |
| A Clinical Study to Assess the Efficacy of Adjuvant Immunotherapy With Cemiplimab in Patients With Surgically Removed Non-small Cell Lung Cancer Who Have Not Received Prior Chemotherapy (NCT06931717) | ETOP IBCSG Partners Foundation | 2026-01-12 |
| EVE TRIAL , ALMA SYSTAM (NCT06646653) | ResQ Medical Ltd | 2026-01-11 |
| Study of Bet v1 Antibodies Effect on Eye Allergy Symptoms in Adolescents and Adults With Birch Pollen Allergy (NCT07309432) | Regeneron Pharmaceuticals | 2026-01-10 |
| Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma (NCT07356037) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2026-01-10 |
| Open-Label Extension Study of MHB018A in Subjects With Thyroid Eye Disease (NCT07262476) | Minghui Pharmaceutical (Hangzhou) Ltd | 2026-01-09 |
| Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis (NCT06654882) | Duke University | 2026-01-09 |
| Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II. (NCT07412132) | University of Sao Paulo | 2026-01-09 |
| A Study of Buntanetap in Participants With PD (NCT07284784) | Annovis Bio Inc. | 2026-01-09 |
| A Phase 3 Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis With Phosphate Binders (NCT07285291) | Taisho Pharmaceutical Co., Ltd. | 2026-01-09 |
| Early Methylene Blue in the Microhemodynamics of Septic Patients (NCT07264543) | Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva | 2026-01-09 |
| Methadone in TKA for Post-op Pain and Opioid Reduction (NCT07226076) | Medical University of South Carolina | 2026-01-08 |
| Study of VYD2311 for the Prevention of COVID-19 (NCT07298434) | Invivyd, Inc. | 2026-01-08 |
| A Study to Evaluate the Safety and Efficacy of SCTC21C in Combination With Bortezomib, Cyclophosphamide, and Dexamethasone in Patients With Newly Diagnosed Systemic Light-Chain Amyloidosis (NDSLCA) (NCT07388602) | Sinocelltech Ltd. | 2026-01-08 |
| A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight (NCT07253285) | Novo Nordisk A/S | 2026-01-08 |
| A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder (NCT07227454) | Janssen Research & Development, LLC | 2026-01-08 |
| A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants (NCT06904261) | Amicus Therapeutics | 2026-01-08 |
| A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant (NCT07095452) | AbbVie | 2026-01-08 |
| LA-HCM Study : Rivaroxaban for Antithrombotic Prevention in Hypertrophic Cardiomyopathy Patients With Abnormal Left Atrial Strain. (NCT07202897) | Rennes University Hospital | 2026-01-07 |
| Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) (NCT07179380) | Insmed Incorporated | 2026-01-07 |
| Tenecteplase Before Interhospital Transfer for EVT in Acute Anterior Circulation LVO at 4.5-24 Hours (NCT07253181) | Xuanwu Hospital, Beijing | 2026-01-06 |
| Safety and Efficacy of ULSC on Disease Severity and Steroid Tapering in Participants With Dermatomyositis/ Polymyositis (DM/PM), Also Known as Idiopathic Inflammatory Myopathy (IIM) (NCT07160205) | Restem, LLC. | 2026-01-06 |
| Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease (NCT07378644) | Skyhawk Therapeutics, Inc. | 2026-01-06 |
| Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NCT07222566) | Pfizer | 2026-01-06 |
| Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma (NCT07174427) | Takara Bio Inc. | 2026-01-05 |
| Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder (NCT07224581) | GRIN Therapeutics, Inc. | 2026-01-05 |
| Ketoanalogue Supplementation for Muscle Protection in CKD 4 and 5 Patients With Moderately Low Protein Diet (KETO-PROT-ACTION) (NCT07374042) | University Hospital, Clermont-Ferrand | 2026-01-05 |
| Compare Radiotherapy Plus Nimotuzumab Versus Radiotherapy Alone in Platinum-ineligible Patients With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (NCT07333274) | Shandong Cancer Hospital and Institute | 2026-01-05 |
| Semaglutide for the Prevention Of Post-Transplant Diabetes Mellitus (NCT06913023) | University Health Network, Toronto | 2026-01-05 |
| Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis (NCT07217587) | Janssen Research & Development, LLC | 2026-01-05 |
| Pulsed Electromagnetic Field on Chronic Anal Fissure Healing (NCT07729709) | Galala University | 2026-01-03 |
| A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion (NCT07063745) | Bristol-Myers Squibb | 2026-01-02 |
| A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM) (NCT07222761) | Regeneron Pharmaceuticals | 2026-01-02 |
| RANKL Inhibition to Combat Sarcopenia in Hip Fracture Patients (NCT07056478) | Prince of Wales Hospital, Shatin, Hong Kong | 2026-01-01 |
| A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab With or Without Pembrolizumab in HER2-high Expression Advanced Gastric or Gastroesophageal Junction Adenocarcinoma. (NCT07315750) | RemeGen Co., Ltd. | 2026-01-01 |
| Evaluation of Neoadjuvant Stereotactic Radiosurgery (SRS) and Multi-fraction SRS Alone for the Treatment of Large Brain Metastases (NCT07329634) | Maciej Harat | 2026-01-01 |
| A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301) (NCT07296445) | SDK Therapeutics, Inc. | 2026-01-01 |
| Efficacy/ Safety of Product DNN.65.21.005 in Patients With Benign Prostatic Hyperplasia (NCT07270432) | Ache Laboratorios Farmaceuticos S.A. | 2026-01-01 |
| Interest of Clomiphene Citrate in Patients With Non-obstructive Azoospermia on the Quantity of Sperm Cells (NCT03615547) | Hospices Civils de Lyon | 2026-01-01 |
| Efficacy of Carbonlife Amniotic Tissue Product in the Treatment of Chronic Wounds (NCT07223892) | Bardia Anvar | 2026-01-01 |
| Prophylactic PIPAC in Patients With High-risk Colorectal Cancer (NCT06839092) | Jeremy Meyer | 2026-01-01 |
| A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function Recovery (NCT07136987) | Open Source Pharma Foundation | 2026-01-01 |
| A Randomised Trial Comparing Trastuzumab Deruxtecan to CDK4/6 Inhibitors in Non-luminal A, ER-positive/HER2-low Metastatic Breast Cancer (NCT06585969) | Danish Breast Cancer Cooperative Group | 2026-01-01 |
| Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination (NCT07604103) | University of Brawijaya | 2026-01-01 |
| De-Escalation Surgery After Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma (NCT07320690) | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 2026-01-01 |
| Active Anti-diabetic Treatment Plus Chemotherapy for Pancreatic Cancer Related Diabetes (NCT07272109) | Fudan University | 2026-01-01 |
| Cervical Facet Injection of Corticosteroids for the Management of Cervicobrachialgia (NCT07084285) | Assistance Publique - Hôpitaux de Paris | 2026-01-01 |
| Evaluation of the Effectiveness of a Cardiac Coherence Exercise on MRI Success and Image Quality in Claustrophobic Patients (NCT07309328) | Fondation Ophtalmologique Adolphe de Rothschild | 2026-01-01 |
| Vaginal Estrogen for Improvement of Outcomes Following Pelvic Organ Prolapse Surgery (NCT07030426) | Sarah Wozney | 2026-01-01 |
| Golidocitinib Combined With Selinexor for CAEBVD (NCT07369739) | Beijing Friendship Hospital | 2026-01-01 |
| Systematic Adjunction of Vasopressine in Septic Shock (NCT07052084) | Assistance Publique Hopitaux De Marseille | 2026-01-01 |
| Lidocaine Patch and Lower Third Molar (NCT07330726) | Fayoum University | 2026-01-01 |
| Randomized Controlled Trial of Different Antibiotic Duration Prior to Prostate Enucleation Surgery (NCT07209150) | Ohio State University | 2026-01-01 |
| Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML (NCT07157514) | Actinium Pharmaceuticals | 2026-01-01 |