| Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe Influenza (NCT03684044) | Hoffmann-La Roche | 2019-01-08 |
| Open-label Treatment in Cushing's Syndrome (NCT03621280) | Cortendo AB | 2019-01-07 |
| Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma (NCT03706079) | AstraZeneca | 2019-01-07 |
| Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis (NCT03737110) | Kiniksa Pharmaceuticals (UK), Ltd. | 2019-01-07 |
| Preventive Treatment of OxaLiplatin Induced peripherAl neuRopathy in Adjuvant Colorectal Cancer (NCT04034355) | Egetis Therapeutics | 2019-01-07 |
| Safety and Efficacy of Emixustat in Stargardt Disease (NCT03772665) | Kubota Vision Inc. | 2019-01-07 |
| Study of NPF-08 in Patients Who Receive Colonoscopy (NCT03794310) | Nihon Pharmaceutical Co., Ltd | 2019-01-05 |
| Virginia Opioid Overdose Treatment InitiatVE (NCT03818399) | Virginia Commonwealth University | 2019-01-04 |
| Noradrenergic Add-on Therapy With Guanfacine (NCT03116126) | Imperial College London | 2019-01-04 |
| A Study Assessing the Safety and Effectiveness of IC2000 and SPY Fluorescence Imaging Systems (SPY-PHI) in the Visualization of Lymphatic Vessels and Identification of Lymph Nodes During Sentinel Lymph Node Biopsy in Subjects With Breast Cancer (NCT03200704) | Novadaq Technologies ULC, now a part of Stryker | 2019-01-04 |
| Daily vs. Every Other Day Oral Iron Supplementation in Patients With Absolute Iron Deficiency Anemia (NCT03725384) | Sunnybrook Health Sciences Centre | 2019-01-04 |
| Dexmedetomidine After Cardiac Surgery for Prevention of Delirium (NCT03477344) | University Hospital, Brest | 2019-01-04 |
| Temocillin Versus a Carbapenem as Initial Intravenous Treatment for ESBL Related Urinary Tract Infections (NCT03543436) | Assistance Publique - Hôpitaux de Paris | 2019-01-04 |
| Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension (NCT02617459) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2019-01-04 |
| A Study to Evaluate the Safety and Tolerability of Intravenous Brivaracetam (BRV) as Replacement for Oral Brivaracetam in Japanese Subjects >=16 Years of Age With Partial Seizures With or Without Secondary Generalization (NCT03685630) | UCB Biopharma S.P.R.L. | 2019-01-04 |
| Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients (NCT03877081) | Hospital Civil de Guadalajara | 2019-01-04 |
| Efficacy and Safety of Oral Ibrexafungerp (SCY-078) vs. Placebo in Subjects With Acute Vulvovaginal Candidiasis (VANISH 303) (NCT03734991) | Scynexis, Inc. | 2019-01-04 |
| Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients (NCT03737643) | AstraZeneca | 2019-01-04 |
| Efficacy & Safety of SmofKabiven Emulsion for Infusion vs Hospital Compounded "All in One" for Parenteral Nutrition (NCT03792100) | Fresenius Kabi | 2019-01-03 |
| Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF Development (NCT03780673) | Judit Pich | 2019-01-03 |
| The Effect of Botulinum Toxin A In Patients With Excessive Gingival Display With And Without Zinc Supplementation (NCT03717987) | Cairo University | 2019-01-03 |
| Neubotulinum Toxin Injection in Cerivical Dystonia (NCT04582929) | Department of Medical Services Ministry of Public Health of Thailand | 2019-01-03 |
| Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar (NCT03662022) | Institute of Tropical Medicine, Belgium | 2019-01-02 |
| Clinical Efficacy and Safety of Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis (NCT03724240) | ASIT Biotech S.A. | 2019-01-02 |
| Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes (NCT03579160) | Brigham and Women's Hospital | 2019-01-02 |
| SAPT Versus DAPT in Incomplete Revascularization After CABG (NCT03789916) | Campus Bio-Medico University | 2019-01-02 |
| Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's Disease (NCT03660176) | Assistance Publique Hopitaux De Marseille | 2019-01-02 |
| A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve (NCT03682536) | Celgene | 2019-01-02 |
| Effects of tDCS on Maximal Isometric Strength and Endurance Test of Trunk Extensors. (NCT03870178) | Universidade Federal do Piauí | 2019-01-02 |
| Propolis as a Treatment Option for Hand Foot and Mouth Disease (NCT06455007) | Murat Sutcu | 2019-01-01 |
| Neoadjuvant Chemotherapy for Pancreatic Cancer Followed by GS and GnP (NCT05268692) | Kochi University | 2019-01-01 |
| Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy ( ISTIAB-0) (NCT03791294) | Università degli Studi dell'Insubria | 2019-01-01 |
| Treatment of Severe Infection With Antihyperlipidemia Drug (NCT03634293) | Wolfson Medical Center | 2019-01-01 |
| Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery (NCT04342065) | South Egypt Cancer Institute | 2019-01-01 |
| Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision (NCT05800301) | Ankara Universitesi Teknokent | 2019-01-01 |
| Metformin in Intrahepatic Cholestasis of Pregnancy (NCT03056274) | Epsom and St Helier University Hospitals NHS Trust | 2019-01-01 |
| Faces: Choices Study (NCT02409862) | University of Florida | 2019-01-01 |
| IT or IA Infusion of PD1/PDL1/CTLA4 Inhibitors Versus IV for Immunotherapy of Head/Neck Cancers (HNC) (NCT03952065) | Second Affiliated Hospital of Guangzhou Medical University | 2019-01-01 |
| Antibacterial Effect of Guava Leaves Extract Mouthwash Compared to Chlorhexidine Mouthwash in High Caries Risk Patients (NCT03773094) | Cairo University | 2019-01-01 |
| Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines (NCT05728632) | Giulio Stefanini | 2019-01-01 |
| Acute Olanzapine and Lipid Response (NCT04181385) | University Health Network, Toronto | 2019-01-01 |
| Vasopressin or Norepinephrine in Vasoplegic Shock After Non-cardiac Surgery (NCT03483753) | University of Sao Paulo | 2019-01-01 |
| Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL, T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients (NCT04446130) | The First Affiliated Hospital of Soochow University | 2019-01-01 |
| Role of Dutasteride in Treatment of Chronic Prostatitis (NCT04756206) | Ain Shams University | 2019-01-01 |
| Melatonin in Youth: N-of-1 Trials in a Stimulant-treated Attention Deficit Hyperactivity Disorder (ADHD) Population (NCT02333149) | University of Alberta | 2019-01-01 |
| A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancer (NCT03811418) | iOMEDICO AG | 2019-01-01 |
| Results of Extended Versus Single Dose Antibiotic Prophylaxis In Orthopedic Revision Arthroplasty in Nijmegen. (NCT06402591) | Radboud University Medical Center | 2019-01-01 |
| Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis. (NCT04767269) | Maharishi Markendeswar University (Deemed to be University) | 2019-01-01 |
| Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis (NCT05118542) | Indonesia University | 2019-01-01 |
| Reactor Thoracostomy (NCT03734471) | Crozer-Keystone Health System | 2019-01-01 |
| Everolimus in Castrated Resistant Prostate Cancer(CRPC)Patients With PI3K-AKT-mTOR Signaling Pathway Deficiency (NCT03580239) | Tianjin Medical University Second Hospital | 2019-01-01 |
| Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy (NCT03789799) | Università degli Studi dell'Insubria | 2019-01-01 |
| Postoperative Pain, Recovery and Discharge Following Robot-assisted Laparoscopic Prostatectomy (NCT03639389) | Karolinska Institutet | 2019-01-01 |
| A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study (NCT03936192) | Eurofarma Laboratorios S.A. | 2019-01-01 |
| Different Techniques for Perineal Skin Closure During Mediolateral Episiotomy Repair (NCT03780530) | Ain Shams University | 2019-01-01 |
| Ultrasound-guided Greater Occipital Nerve Block in Children Undergoing Posterior Fossa Craniotomy (NCT03762343) | Kasr El Aini Hospital | 2019-01-01 |
| Ruxolitinib as add-on Therapy in Steroid-refractory Graft-vs-host Disease (NCT05663827) | Yi-Lun Wang | 2019-01-01 |
| Infusion of PD1/PDL1/CTLA4 Inhibitors Via Hepatic Arterial for Immunotherapy of Hepatocellular Carcinoma (NCT03949231) | Second Affiliated Hospital of Guangzhou Medical University | 2019-01-01 |
| Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients (NCT03295058) | Assiut University | 2019-01-01 |
| Delta Q Value to Discriminate Detrusor Underactivity From Bladder Outlet Obstruction (NCT05359484) | Ain Shams University | 2019-01-01 |
| Librata Endometrial Ablation Device Treatment to Reduce Menstrual Blood Loss (NCT03725306) | LiNA Medical | 2019-01-01 |
| Study Comparing Caspofungin to Placebo for the Treatment of ICU Intra-abdominal Candidiasis (NCT03580733) | Centre Hospitalier Universitaire, Amiens | 2019-01-01 |
| 7 Days Versus 14 Days of Antibiotics for Neonatal Sepsis (NCT03280147) | Indian Council of Medical Research | 2019-01-01 |
| Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial. (NCT03435744) | Pakistan Institute of Living and Learning | 2019-01-01 |
| Nondependent Lung Ventilation and Fluid Responsiveness (NCT02191410) | Imam Abdulrahman Bin Faisal University | 2019-01-01 |
| Averting Complications of Proton Pump Inhibitor Therapy by Effervescent Calcium Magnesium Citrate (NCT03812380) | University of Texas Southwestern Medical Center | 2019-01-01 |
| Lenvatinib Plus PD-1 Antibody vs TACE for Intermediate-stage HCC Beyond Up-to-seven Criteria (NCT03791918) | Sun Yat-sen University | 2019-01-01 |
| S-1 for 9 Months Versus 1 Year for Stage II Gastric Cancer (SMAC） (NCT03941561) | Fudan University | 2019-01-01 |
| OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps (NCT03747458) | Optinose US Inc. | 2018-12-31 |
| Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma (MK-7902-002/E7080-G000-311/LEAP-002) (NCT03713593) | Merck Sharp & Dohme LLC | 2018-12-31 |
| Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial (NCT03508830) | University of California, San Francisco | 2018-12-30 |
| Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC) (NCT03711305) | Jiangsu HengRui Medicine Co., Ltd. | 2018-12-30 |
| Randomized Evaluation of Radotinib Versus Imatinib in Phase III Study for Efficacy With Chinese Patients (RERISE China) (NCT03722420) | Il-Yang Pharm. Co., Ltd. | 2018-12-28 |
| A Study Comparing the Efficacy and Safety of G-CHOP Versus R-CHOP in Untreated Diffuse Large B-cell Lymphoma Patients (NCT03650933) | Nanjing Yoko Biomedical Co., Ltd. | 2018-12-28 |
| Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS (NCT03650114) | Novartis Pharmaceuticals | 2018-12-28 |
| A Phase 3 Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG) (NCT03759366) | Alexion Pharmaceuticals, Inc. | 2018-12-28 |
| DEF-315 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY (NCT03719612) | Lantheus Medical Imaging | 2018-12-28 |
| A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NCT03735121) | Hoffmann-La Roche | 2018-12-27 |
| Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04] (NCT03734029) | Daiichi Sankyo | 2018-12-27 |
| Actual Use and Compliance Study Of Ibuprofen 600 Mg Immediate Release/Extended Release Tablets In At-Risk OTC Consumers (NCT03722238) | Pfizer | 2018-12-27 |
| Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756) (NCT03725059) | Merck Sharp & Dohme LLC | 2018-12-27 |
| Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDS (NCT03699475) | Bellicum Pharmaceuticals | 2018-12-27 |
| Peanut Oral Immunotherapy Study of Early Intervention for Desensitization (NCT03736447) | Aimmune Therapeutics, Inc. | 2018-12-27 |
| Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in Japan (NCT03873116) | BioCryst Pharmaceuticals | 2018-12-27 |
| Procollagen-3 Driven Corticosteroids for Persistent Acute Respiratory Distress Syndrome (NCT03371498) | Assistance Publique Hopitaux De Marseille | 2018-12-27 |
| Safety and Efficacy of Y-shape Pegylated Somatropin in Growth Hormone Deficiency Children (NCT04513171) | Xiamen Amoytop Biotech Co., Ltd. | 2018-12-26 |
| Phase 3 Study to Evaluate the Safety and Efficacy of Galnobax® in Treating Diabetic Foot Ulcers (NCT03998436) | Novalead Pharma Private Limited | 2018-12-26 |
| MT10109L in the Treatment of Glabellar Lines (NCT03795922) | Medy-Tox | 2018-12-24 |
| Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676) (NCT03711032) | Merck Sharp & Dohme LLC | 2018-12-24 |
| Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 ) (NCT03748134) | Innovent Biologics (Suzhou) Co. Ltd. | 2018-12-24 |
| RRx-001 Sequentially With a Platinum Doublet or a Platinum Doublet in Third-Line or Beyond in Patients With Small Cell Lung Cancer (NCT03699956) | EpicentRx, Inc. | 2018-12-24 |
| Study of Brimonidine Tartrate Nanoemulsion Eye Drops in Patients With Ocular Graft-vs-Host Disease (NCT03591874) | Ocugen | 2018-12-23 |
| Catheter-Directed Thrombolysis Versus Anticoagulation Monotherapy in Intermediate-High Risk PE (NCT05172115) | Rajaie Cardiovascular Medical and Research Center | 2018-12-22 |
| Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia (NCT03804268) | Allergan | 2018-12-21 |
| A Study of First-line JS001 and Nab-paclitaxel Versus Palcelbo and Nab-Paclitaxel in Participants With Advanced Recurrent or Metastatic TNBC (NCT03777579) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2018-12-21 |
| A Study of S6G5T-3 in the Treatment of Acne Vulgaris (NCT03761784) | Sol-Gel Technologies, Ltd. | 2018-12-21 |
| Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD) (NCT03794583) | United Therapeutics | 2018-12-21 |
| Impact of TheraWorx Foam on Symptom Relief in Thumb Arthritis (NCT03770091) | John Fowler | 2018-12-21 |
| Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment (NCT04085276) | Shanghai Junshi Bioscience Co., Ltd. | 2018-12-21 |
| A Multicenter, Open-Label Retreatment Study of the Safety and Effectiveness of PN40082 for Lip Augmentation (NCT04029519) | Prollenium Medical Technologies Inc. | 2018-12-21 |