| Reperfusion Completion Via Local Arterial Infusion of Tenecteplase After Incomplete Mechanical Thrombectomy (NCT07471282) | Chuansheng Zhao | 2026-03-01 |
| PET Guided Dose Reduction for InvOlved Site Radiotherapy In Early sTage Unfavourable Hodgkin Lymphoma (NCT07256158) | Fondazione Italiana Linfomi - ETS | 2026-03-01 |
| QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated Low Density Lipoprotein Cholesterol (LDL-C) (NCT07441317) | Qilu Pharmaceutical Co., Ltd. | 2026-03-01 |
| Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial (NCT07015892) | Instituto de Investigación Biomédica de Salamanca | 2026-03-01 |
| A Clinical Trial to Assess the Effectiveness of NRF2 Activator (Oral Sodium-copper- Chlophyllin ) in Locally Advanced Cervical Cancer to Reduce Late Radiotherapy Toxicity. (NCT07164534) | Tata Memorial Hospital | 2026-03-01 |
| Melatonin vs Midazolam in Children Undergoing Tonsillectomy (NCT07336095) | Ain Shams University | 2026-03-01 |
| Targeted Hypothermia Versus Targeted Normothermia After Convulsive Refractory Status Epilepticus (NCT07383779) | Versailles Hospital | 2026-03-01 |
| A Phase III Clinical Study of WX390 Combined With Toripalimab Versus Investigator's Choice of Therapy in Patients With Recurrent or Metastatic Cervical Cancer Who Have Failed Prior Platinum-Based Treatment (NCT07392060) | Shanghai Jiatan Pharmatech Co., Ltd | 2026-02-28 |
| A Study to Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia (NCT07421297) | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 2026-02-28 |
| A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis (NCT07420257) | CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | 2026-02-28 |
| Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (NCT07456176) | Ain Shams University | 2026-02-28 |
| A Study of FG-M108+Chemotherapy vs Placebo+Chemotherapy in Claudin18.2-positive Pancreatic Cancer (NCT07383922) | FutureGen Biopharmaceutical (Beijing) Co., Ltd | 2026-02-28 |
| Comparing the Efficacy of Different Durations of Maribavir Treatment Regimens in Allo-HSCT (NCT07511127) | Ruijin Hospital | 2026-02-28 |
| A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows (NCT07427797) | Ipsen | 2026-02-27 |
| A Study to Evaluate HLX22 in Combination With HLX87 in Patients With HER2-Positive Recurrent or Metastatic Breast Cancer (NCT07294508) | Shanghai Henlius Biotech | 2026-02-27 |
| Adding Aprepitant to a Multimodal Strategy for the Prevention of Postoperative Nausea and Vomiting in High-risk Outpatient Surgical Patients (NCT07248280) | Centre hospitalier de l'Université de Montréal (CHUM) | 2026-02-27 |
| Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial (NCT07166406) | NRG Oncology | 2026-02-26 |
| Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide (NCT07454837) | Mirum Pharmaceuticals, Inc. | 2026-02-26 |
| Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth (NCT07464886) | University of Cincinnati | 2026-02-26 |
| A Clinical Trial of Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried in a Population Aged 10 to 60 Years (NCT07275645) | Ab&B Bio-tech Co., Ltd.JS | 2026-02-26 |
| Famitinib Combined With SHR-A1811, Versus SHR-A1811 for CDK4/6 Inhibitors-resistent Advanced HR+/HER2- Breast Cancer With SNF4 Subtype (NCT07382687) | Fudan University | 2026-02-26 |
| Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease (NCT07404865) | Vor Biopharma | 2026-02-26 |
| HEALEY ALS Platform Trial - Regimen I NUZ-001 (NCT07410806) | Merit E. Cudkowicz, MD | 2026-02-25 |
| Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer (NCT07357298) | H. Lee Moffitt Cancer Center and Research Institute | 2026-02-25 |
| A Study of HDM1005 in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone (NCT07394114) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2026-02-24 |
| AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight (NCT07339423) | Novo Nordisk A/S | 2026-02-24 |
| Surgery With or Without Neoadjuvant Treatment of SBRT Plus Chemoimmunotherapy in Resectable Locally Advanced Oral and HPV-unrelated Oropharyngeal Squamous Cell Carcinoma (NCT07402538) | Sun Yat-sen University | 2026-02-24 |
| Clinical Trial to Evaluate the Efficacy and Safety of Platelet-rich Plasma Infiltration in Chronic Omalgia (NCT07448285) | Biobizkaia Health Research Institute | 2026-02-24 |
| Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo (NCT06694740) | Assistance Publique - Hôpitaux de Paris | 2026-02-24 |
| Study on the Efficacy and Safety of Mecobalamin in Preventing Taxane-related Peripheral Neuropathy (NCT07423390) | Qinghai Red Cross Hospital | 2026-02-24 |
| A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D) (NCT07400653) | Pfizer | 2026-02-24 |
| A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4) (NCT07391657) | AstraZeneca | 2026-02-23 |
| Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol (NCT07484217) | Axsome Therapeutics, Inc. | 2026-02-23 |
| REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool (NCT07280065) | Senseye, Inc. | 2026-02-23 |
| Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Without Concurrent Surufatinib in Neoadjuvant Therapy for Mid-to-low Localized Rectal Cancer of High-risk Criteria (NCT07505472) | The First Hospital of Jilin University | 2026-02-23 |
| Transverse vs Longitudinal Mucosal Incision During POEM (NCT07425977) | Universidad Nacional de Colombia | 2026-02-22 |
| Conversion Surgery for Gastric Cancer With Peritoneal Metastases (CONVERGENCE) (NCT07241715) | National University Hospital, Singapore | 2026-02-21 |
| AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction (NCT07368959) | Aurion Biotech | 2026-02-19 |
| Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches (NCT07354464) | University Hospital, Clermont-Ferrand | 2026-02-19 |
| Comparing Adjuvant Treatments for High Tone Pelvic Floor Dysfunction (NCT07404397) | University of Michigan | 2026-02-18 |
| A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows (NCT07435428) | Ipsen | 2026-02-18 |
| A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well (NCT07361302) | Boehringer Ingelheim | 2026-02-17 |
| Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant (NCT07495852) | Glaukos Corporation | 2026-02-17 |
| Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis (NCT07362017) | Vanda Pharmaceuticals | 2026-02-17 |
| Anesthesia sTrategy foR Organ Procurement In braiN dEath (NCT07166991) | University Hospital, Grenoble | 2026-02-17 |
| A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer (NCT07409272) | Astellas Pharma Global Development, Inc. | 2026-02-17 |
| COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME (NCT07449936) | EyePoint Pharmaceuticals, Inc. | 2026-02-16 |
| A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS) (NCT07220083) | Boehringer Ingelheim | 2026-02-16 |
| A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021) (NCT07318558) | Merck Sharp & Dohme LLC | 2026-02-16 |
| Transarterial Chemoembolization (TACE) Plus ABCB1 Inhibition Versus TACE Alone in Patients With Hepatocellular Carcinoma (NCT07302919) | University Hospital, Basel, Switzerland | 2026-02-16 |
| Golidocitinib Versus Placebo as Maintenance Therapy in PTCL Patients With Response (CR/PR) After First-Line Chemotherapy (NCT07414758) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2026-02-15 |
| Effects of Lower Body Positive Pressure Therapy Versus Alpha Lipoic Acid and Omega-3 Fatty Acids on Knee Osteoarthritis (NCT07399743) | Badr University | 2026-02-15 |
| Reducing the Burden of Cardiovascular Events With Antiplatelet Therapy in Patients With IntraCerebral Haemorrhage (NCT07243704) | Christian Medical College and Hospital, Ludhiana, India | 2026-02-15 |
| Semaglutide for Smoking Cessation in Patients With Diabetes (NCT07059377) | Ottawa Heart Institute Research Corporation | 2026-02-13 |
| PROGAIN Trial in Gastric Cancer Surgery (NCT07488611) | Soonchunhyang University Hospital | 2026-02-13 |
| Holy Basil in The Treatment of Dyspepsia (NCT07175272) | Mahidol University | 2026-02-13 |
| A Clinical Trial of Flonoltinib Maleate for Intermediate or High-Risk Myelofibrosis (NCT07317700) | Chengdu Zenitar Biomedical Technology Co., Ltd | 2026-02-13 |
| Study of the Efficacy and Safety of ICP-332 in Participants With Chronic Spontaneous Urticaria (NCT07378527) | Beijing InnoCare Pharma Tech Co., Ltd. | 2026-02-13 |
| A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy (NCT07210723) | Kardigan, Inc. | 2026-02-13 |
| Immunomodulatory Therapy to Restore Ovarian Function and Improve Fertility in Women With Autoimmune Premature Ovarian Insufficiency (NCT07509840) | Angelica Lindén Hirschberg | 2026-02-12 |
| A Trial of SHR-A2102 With Adebrelimab in Locally Advanced or Metastatic Urothelial Carcinoma (NCT07393542) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-02-12 |
| A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease (NCT07363694) | Pfizer | 2026-02-11 |
| Thymosin-α1 for Recurrent Implantation Failure (NCT07675980) | Fakih IVF Fertility Center | 2026-02-11 |
| Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS (NCT07197944) | Zealand Pharma | 2026-02-11 |
| Ribociclib in Hormone Receptor-positive, HER2-negative Early Breast Cancer With Residual Disease After Neoadjuvant Chemotherapy (NCT07400523) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2026-02-10 |
| Trial Evaluating Hypo-fractionated Accelerated Versus Conventional Fractionated Adjuvant RT in Head & Neck Malignancies (NCT07573956) | All India Institute of Medical Sciences | 2026-02-10 |
| IBI354 With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (NCT07377643) | Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. | 2026-02-10 |
| Aspirin Continuation or Interruption in Patients at Moderate Risk for Cardiovascular Events Undergoing Colonoscopy and/or Polypectomy (NCT07052799) | Chinese University of Hong Kong | 2026-02-10 |
| A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight (NCT07369011) | Eli Lilly and Company | 2026-02-10 |
| A Phase III Clinical Trial of NTQ1062 in Combination With Fulvestrant for the Treatment of Advanced or Metastatic HR+/HER2- Breast Cancer (NCT07393321) | Nanjing Chia-tai Tianqing Pharmaceutical | 2026-02-10 |
| A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin (NCT07392190) | Eli Lilly and Company | 2026-02-10 |
| A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis (NCT07201922) | Boehringer Ingelheim | 2026-02-10 |
| A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout (NCT07388498) | Amgen | 2026-02-09 |
| A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment (NCT07201129) | Viatris Innovation GmbH | 2026-02-09 |
| 3% Diquafosol Ophthalmic Solution for Active Moderate-to-Severe Vernal Keratoconjunctivitis (NCT06903884) | The University of Hong Kong | 2026-02-09 |
| A Study of Brenipatide in Adult Participants With Major Depressive Disorder (NCT07412756) | Eli Lilly and Company | 2026-02-09 |
| CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME (NCT07449923) | EyePoint Pharmaceuticals, Inc. | 2026-02-09 |
| Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Pelvic Pain Suggestive of Dysmenorrhea (NCT06995287) | Nantes University Hospital | 2026-02-09 |
| MSA-01 in Multiple System Atrophy (NCT07446894) | Tokyo University | 2026-02-09 |
| Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight (NCT07353931) | Eli Lilly and Company | 2026-02-09 |
| A Study of XW003 in Obese Participants With Obstructive Sleep Apnea But Not Receive Positive Airway Pressure Therapy (NCT07387094) | Hangzhou Sciwind Biosciences Co., Ltd. | 2026-02-09 |
| Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal Vaccination (NCT07425392) | Vaxcyte, Inc. | 2026-02-09 |
| A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults (NCT07220772) | Regeneron Pharmaceuticals | 2026-02-09 |
| A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes (NCT07321886) | Eli Lilly and Company | 2026-02-06 |
| A Trial to Evaluate the Safety and Immunogenicity of VLA1553 in Healthy Children (NCT07133178) | Valneva Austria GmbH | 2026-02-06 |
| Efficacy and Safety of SBRT Combined With Becotatug Vedotin (MRG003) in EGFR-Positive Metastatic Tumor Patients With Oligometastases (NCT07481799) | Ming-Yuan Chen | 2026-02-06 |
| "Effect of Vitamin E (α-Tocopherol) on Clinical Activity and Inflammation in Rheumatoid Arthritis" (NCT06915701) | University of Guadalajara | 2026-02-06 |
| Tarlatamab vs Standard of Care Chemotherapy in Patients With Pre-treated Advanced, Pulmonary or Gastroenteropancreatic Poorly Differentiated Neuroendocrine Carcinomas (NECs) (NCT06937905) | Intergroupe Francophone de Cancerologie Thoracique | 2026-02-06 |
| JSKN003 Versus Physician Choiced Treatment in Patients With HER2-positive and Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-Fu, and Irinotecan (NCT07384377) | Shanghai JMT-Bio Inc. | 2026-02-06 |
| Becotatug Vedotin (MRG003) in Combination With PD-1 Inhibitor Versus PD-1 Inhibitor for the Treatment of EGFR-positive, CPS≥1 Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma (NCT07524452) | Ming-Yuan Chen | 2026-02-06 |
| A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE) (NCT07222332) | Eli Lilly and Company | 2026-02-05 |
| A Study of Rocbrutinib Versus Investigator's Choice of BTK Inhibitors in Patients With Relapsed or Refractory Mantle Cell Lymphoma (NCT07377578) | Guangzhou Lupeng Pharmaceutical Company LTD. | 2026-02-05 |
| A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma (NCT07258511) | Janssen Research & Development, LLC | 2026-02-04 |
| A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA) (NCT07340827) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2026-02-04 |
| Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia (NCT06761560) | Yves Pastore | 2026-02-03 |
| to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and Menorrhagia (NCT07378098) | JW Pharmaceutical | 2026-02-03 |
| Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 (NCT07431281) | AstraZeneca | 2026-02-03 |
| Olanzapine Plus Metoclopramide for the Prevention of Opioid-Induced Nausea and Vomiting (NCT07208305) | Affiliated Hospital of Qinghai University | 2026-02-03 |
| Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty (NCT07214311) | Peptilogics | 2026-02-03 |
| TELITACICEPT IN INFLAMMATORY MYOPATHIES(TELITACICEPT-IM) (NCT07355257) | Zhongming Qiu | 2026-02-02 |