| A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes) (NCT04058353) | Vertex Pharmaceuticals Incorporated | 2019-08-28 |
| Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients (NCT04075006) | King Faisal Specialist Hospital & Research Center | 2019-08-28 |
| Efficacy and Safety of CHF 6532 in Patients With Uncontrolled Severe Eosinophilic Asthma (NCT04049175) | Chiesi Farmaceutici S.p.A. | 2019-08-28 |
| Prophylactic Use of Hydroxycobolamin in Vasoplegic Syndrome in Adult Patients Undergoing Cardiopulmonary Bypass (NCT06160219) | Ain Shams University | 2019-08-28 |
| Palbociclib for HR Positive / HER2-negative Isolated Locoregional Recurrence of Breast Cancer (NCT03820830) | ETOP IBCSG Partners Foundation | 2019-08-27 |
| Efficacy and Safety of Gadopiclenol for Body Magnetic Resonance Imaging (MRI) (NCT03986138) | Guerbet | 2019-08-27 |
| A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With PNH (NCT04085601) | Apellis Pharmaceuticals, Inc. | 2019-08-27 |
| Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections (NCT04832607) | Tobias Feuchtinger | 2019-08-27 |
| Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment (NCT04237532) | Nourhan M.Aly | 2019-08-27 |
| Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC (NCT03991403) | Samsung Medical Center | 2019-08-27 |
| Betaglucin 0.2% Versus Imiquimod 5% in Treatment of Ano-genital Warts: Combined Results From Triple Blind Controlled Study (NCT03901690) | Centro de Investigaciones Medicas y Ensayos Clinicos Dr Italo Fabbri | 2019-08-27 |
| Extended Pelvic Lymph Node Dissection vs. no Pelvic Lymph Node Dissection at Radical Prostatectomy for intermediate-and High-risk Prostate Cancer (NCT03921996) | Swiss Cancer Institute | 2019-08-27 |
| The Role of Secondary Bile Acids in Intestinal Inflammation (NCT03724175) | Stanford University | 2019-08-26 |
| Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS) (NCT04032158) | EMD Serono Research & Development Institute, Inc. | 2019-08-26 |
| Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations (NCT04053634) | AstraZeneca | 2019-08-26 |
| Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients (NCT03867201) | Novartis Pharmaceuticals | 2019-08-26 |
| Smartphone Based Smoking Cessation Intervention (NCT03740490) | University of Oklahoma | 2019-08-26 |
| Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria (NCT03847090) | Allena Pharmaceuticals | 2019-08-26 |
| The Impact of Magnesium on Exercise Tolerance, Quality of Life and Clinical Outcomes in Chronic Heart Failure Patients (NCT03840226) | Sheba Medical Center | 2019-08-25 |
| CATER: Comprehensive Alveolar and Tooth Esthetic Replacement (NCT04082143) | University of Illinois at Chicago | 2019-08-25 |
| World Maternal Antifibrinolytic Trial_2 (NCT03475342) | London School of Hygiene and Tropical Medicine | 2019-08-24 |
| Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines (NCT05967442) | Wake Forest University Health Sciences | 2019-08-23 |
| International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma (NCT04043494) | University Hospital Muenster | 2019-08-23 |
| Clinical Trial to Evaluate the Efficacy and Safety of MEDITOXIN® in Subject With Idiopathic Overactive Bladder (NCT04113941) | Medy-Tox | 2019-08-23 |
| Study Compare Adjuvant Chemotherapy, Chemoradiotherapy and Surgery Alone for pN1-2(pT1b-3N1-2M0) Esophageal Carcinoma (NCT04009265) | Fujian Medical University Union Hospital | 2019-08-23 |
| Intravenous Ascorbic Acid Administration in Hysterectomy (NCT03965637) | Shahid Beheshti University | 2019-08-23 |
| To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema (NCT04058067) | Novartis Pharmaceuticals | 2019-08-23 |
| Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer (NCT03914612) | National Cancer Institute (NCI) | 2019-08-22 |
| Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis (NCT04636242) | Rothman Institute Orthopaedics | 2019-08-22 |
| Anti-VEGF Intravitreous Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery (NCT04063358) | Second Military Medical University | 2019-08-22 |
| Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care (NCT04062201) | Wits Health Consortium (Pty) Ltd | 2019-08-22 |
| Controlling Rapid Atrial Fibrillation With Dexmedetomidine (NCT04042727) | Stony Brook University | 2019-08-21 |
| Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis (NCT04028492) | Vanda Pharmaceuticals | 2019-08-20 |
| Detection of False Positives From First-trimester Preeclampsia Screening (StopPRE) at the Second-trimester of Pregnancy (NCT03741179) | Hospital Universitari Vall d'Hebron Research Institute | 2019-08-20 |
| Nitropaste in Breast Reduction (NCT04321967) | Icahn School of Medicine at Mount Sinai | 2019-08-20 |
| Paclitaxel (Albumin-bound) and Oxaliplatin for Advanced Hepatobiliary and Malignant Tumors (NCT04060472) | Dong Wang | 2019-08-20 |
| Study to Assess Immunegnicity & Safety of Pentavalent Meningococcal Vaccine (NmCV-5) (NCT03964012) | Serum Institute of India Pvt. Ltd. | 2019-08-20 |
| Extension Study to Provide Adjuvant Treatment Following Neoadjuvant Treatment and Surgical Resection in Protocol TX05-03 (NCT04109391) | Tanvex BioPharma USA, Inc. | 2019-08-20 |
| A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation (NCT04002297) | BeOne Medicines | 2019-08-20 |
| The Effect of Multiple Injection of Platlet-rich Plasma in Chronic Patellar Tendinopathy (NCT03986372) | Chang Gung Memorial Hospital | 2019-08-20 |
| A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly (NCT04076462) | Camurus AB | 2019-08-19 |
| A Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children (NCT04070326) | Shire | 2019-08-19 |
| A Study to Compare QL1207 to Eylea® in Subjects With Wet Age-related Macular Degeneration (wAMD) (NCT05345236) | Qilu Pharmaceutical Co., Ltd. | 2019-08-19 |
| Efficacy and Safety of Xacrel® (Ocrelizumab) in Participants With Relapsing Remitting Multiple Sclerosis (NCT04966338) | Cinnagen | 2019-08-19 |
| A Study to Compare Different Antibiotics and Different Modes of Fluid Treatment for Children With Severe Pneumonia (NCT04041791) | University of Oxford | 2019-08-19 |
| Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer (NCT03811015) | National Cancer Institute (NCI) | 2019-08-16 |
| Apatinib and Etoposide Capsule Versus Weekly Paclitaxel in Patients With Platinum Resistant Ovarian Cancer (NCT04000295) | Jiangsu HengRui Medicine Co., Ltd. | 2019-08-16 |
| 89Zr-TLX250 for PET/CT Imaging of ccRCC- ZIRCON Study (NCT03849118) | Telix Pharmaceuticals (Innovations) Pty Limited | 2019-08-15 |
| Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia (NCT04119050) | Janssen Research & Development, LLC | 2019-08-15 |
| Tuberculosis Preventive Therapy Among Latent Tuberculosis Infection in HIV-infected Individuals (NCT03785106) | The HIV Netherlands Australia Thailand Research Collaboration | 2019-08-15 |
| Plasma Exchange in Acute on Chronic Liver Failure (NCT04051437) | Asian Institute of Gastroenterology, India | 2019-08-15 |
| Impact of Atorvastatin on Prostate Cancer Progression During ADT (NCT04026230) | Tampere University Hospital | 2019-08-15 |
| Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases (NCT03870750) | Fred Hutchinson Cancer Center | 2019-08-15 |
| A Study of the Effectiveness of Venetoclax in Combination With Azacitidine or Decitabine in an Outpatient Setting in Patients With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy (NCT03941964) | AbbVie | 2019-08-15 |
| Treating Idiopathic Inflammatory Myopathies Related Reduced Bone Mineral Density With Denosumab or Zoledronic Acid (NCT04034199) | Kwong Wah Hospital | 2019-08-15 |
| A Randomized, Double-blind, Placebo Controlled Phase III Study to Investigate Efficacy and Safety of First-Line Treatment With HLX10 + Chemotherapy (Carboplatin-Nanoparticle Albumin Bound (Nab) Paclitaxel) in Patients With Stage IIIB/IIIC or IV NSCLC (NCT04033354) | Shanghai Henlius Biotech | 2019-08-14 |
| Long Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003) (NCT04053387) | Organon and Co | 2019-08-13 |
| A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector for the Subcutaneous Self-injection of Bimekizumab Solution by Subjects With Active Psoriatic Arthritis (NCT04109976) | UCB Biopharma SRL | 2019-08-13 |
| Study of TQ-B3139 Versus Crizotinib in the First Line Treatment of Subjects With Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC) (NCT04009317) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2019-08-13 |
| Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease (NCT03933397) | Duke University | 2019-08-13 |
| Cenobamate Open-Label Extension Study for YKP3089C025 (NCT03961568) | SK Life Science, Inc. | 2019-08-13 |
| Impact of Budesonide Irrigations on Patients With Chronic Rhinosinusitis and Impact on Sinus Surgery Rates (NCT03519061) | Kaiser Permanente | 2019-08-13 |
| In Vivo Effects of Fibrinogen Concentrate (FC) Versus Cryoprecipitate on the Neonatal Fibrin Network Structure After Cardiopulmonary Bypass (CPB) (NCT03932240) | Emory University | 2019-08-13 |
| S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration (NCT04071457) | SWOG Cancer Research Network | 2019-08-13 |
| A Study to Assess the Long-term Safety, Tolerability, and Efficacy of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis (NCT04009499) | UCB Biopharma SRL | 2019-08-13 |
| A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer (NCT04028050) | Hoffmann-La Roche | 2019-08-12 |
| A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials (NCT04064060) | Celgene | 2019-08-12 |
| A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (NCT04035005) | Hoffmann-La Roche | 2019-08-12 |
| RFA Versus SBRT for Recurrent Small HCC (NCT04047173) | Sun Yat-sen University | 2019-08-12 |
| Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis (NCT04036435) | Bristol-Myers Squibb | 2019-08-12 |
| Intra-dermal With Topical Imiquimod Pretreatment Versus Intra-muscular Hepatitis B Vaccination in IBD Patients (NCT04083157) | The University of Hong Kong | 2019-08-12 |
| A Study of KHK4827 in Subjects With Palmoplantar Pustulosis (NCT04061252) | Kyowa Kirin Co., Ltd. | 2019-08-10 |
| A Study Evaluating the Long-term Safety of VX-445 Combination Therapy (NCT04043806) | Vertex Pharmaceuticals Incorporated | 2019-08-09 |
| Evaluation of Symptom Benefit Rate of Trabectedin/PLD in Patients With Recurrent Ovarian Cancer (NCT03690739) | AGO Research GmbH | 2019-08-09 |
| The Value of Screening for HPR in Patients Undergoing Lower Extremity Arterial Endovascular Interventions (NCT04007055) | Marissa Jarosinski | 2019-08-09 |
| A Study to Compare Efficacy and Safety of Nanogen's Darbepoetin Alfa With Aranesp® (Amgen) in the Treatment of Anemia in Chronic Kidney Disease Patients on Dialysis (CKD) (NCT05585645) | Nanogen Pharmaceutical Biotechnology Joint Stock Company | 2019-08-08 |
| A Efficacy and Safety Study of Anlotinib Hydrochloride Capsule Combined With Chemotherapy Versus Placebo Combined With Chemotherapy as First-line Treatment in Subjects With Advanced Non-squamous Cell Non-small Cell Lung Cancer (NCT04439890) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2019-08-08 |
| A Study to Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria (NCT04058158) | Samsung Bioepis Co., Ltd. | 2019-08-07 |
| Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment (NCT03926052) | Yale University | 2019-08-07 |
| Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-Responders (NCT03946111) | Yale University | 2019-08-07 |
| PRRT Versus PRRT Plus Chemotherapy in GEP NET (PReCedeNT Trial) (NCT07185672) | Tata Memorial Hospital | 2019-08-07 |
| A Trial of Cervidil for Outpatient Pre-induction of Cervical Ripening (NCT03806231) | Intermountain Health Care, Inc. | 2019-08-07 |
| Pregabalin Treatment for RDEB Pain and Itch (NCT03928093) | The Hospital for Sick Children | 2019-08-07 |
| Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections (NCT03840148) | Venatorx Pharmaceuticals, Inc. | 2019-08-07 |
| A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive Disorder (NCT04007367) | Biogen | 2019-08-06 |
| PRACTECAL-PKPD Sub Study (NCT04081077) | Medecins Sans Frontieres, Netherlands | 2019-08-06 |
| Extended-release Pharmacotherapy for Opioid Use Disorder (NCT05164549) | King's College London | 2019-08-06 |
| Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring (NCT03967197) | Centre hospitalier de l'Université de Montréal (CHUM) | 2019-08-06 |
| Understanding Cognition, Oxytocin & Pain in Elders (NCT03878589) | University of Florida | 2019-08-06 |
| A Study of GC3107(BCG Vaccine) in Healthy Infants (NCT03947138) | Green Cross Corporation | 2019-08-06 |
| A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Dyskinesia in Cerebral Palsy in Children and Adolescents (NCT03813238) | Teva Branded Pharmaceutical Products R&D, Inc. | 2019-08-06 |
| Rhopressa for Corneal Edema Associated With Fuchs Dystrophy (NCT04051463) | Price Vision Group | 2019-08-05 |
| A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC) (NCT04008030) | Bristol-Myers Squibb | 2019-08-05 |
| Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease (NCT03854019) | The University of Texas Health Science Center, Houston | 2019-08-05 |
| Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis (NCT04064411) | Radius Health, Inc. | 2019-08-05 |
| Management Of Pain After Cesarean Trial (NCT03929640) | Milton S. Hershey Medical Center | 2019-08-05 |
| A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Allergic Conjunctivitis (NCT04050865) | Ocular Therapeutix, Inc. | 2019-08-05 |
| Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease (NCT03943459) | InCor Heart Institute | 2019-08-02 |
| Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1) (NCT04275323) | Beijing Northland Biotech. Co., Ltd. | 2019-08-02 |
| Rifaximin and Misoprostol Combination Therapy for Healing of Small Bowel Ulcers in Aspirin Users (NCT03962283) | Chinese University of Hong Kong | 2019-08-02 |