| Study to Assess the Safety and Immunogenicity of a Single Dose of a Quadrivalent Meningococcal (MenACYW) Conjugate Vaccine in Older Adults Who Received a Primary Vaccination (3 or More Years Earlier) in Study MET49 (NCT04142242) | Sanofi Pasteur, a Sanofi Company | 2019-10-04 |
| Utility of Sodium Lactate Infusion During Septic Shock (NCT03528213) | University Hospital, Lille | 2019-10-04 |
| A Study Evaluating the Efficacy and Safety of VX-445/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects, Homozygous for F508del (NCT04105972) | Vertex Pharmaceuticals Incorporated | 2019-10-03 |
| Double-Blind Comparison of the Efficacy and Safety of C213 to Placebo for the Acute Treatment of Cluster Headaches (NCT04066023) | Zosano Pharma Corporation | 2019-10-03 |
| Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN (NCT03955445) | Novartis Pharmaceuticals | 2019-10-03 |
| Topical Ruxolitinib Evaluation in Vitiligo Study 2 (TRuE-V2) (NCT04057573) | Incyte Corporation | 2019-10-03 |
| TACE Plus Sorafenib Versus TACE Alone for Recurrent Intermediate Hepatocellular Carcinoma (NCT04103398) | Sun Yat-sen University | 2019-10-02 |
| A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer (NCT03975647) | Seagen, a wholly owned subsidiary of Pfizer | 2019-10-02 |
| Short vs Long Duration Dual Antiplatelet Therapy in Patients Undergoing Lower Extremity Endovascular Revascularization (NCT02433587) | University Hospitals Cleveland Medical Center | 2019-10-01 |
| Study of 18F-DCFPyL PET/CT Imaging in Patients With Prostate Cancer (NCT03800784) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2019-10-01 |
| Correlation of Serum Adalimumab Levels at an Administration of 40 mg Weekly vs 80 mg Every Two Weeks (NCT04404517) | Hospital Universitario La Paz | 2019-10-01 |
| OMEGA, Local Ablative Therapy in Oligometastatic NSCLC (NCT03827577) | Azienda Ospedaliera Universitaria Integrata Verona | 2019-10-01 |
| Postoperative Hyperbaric Oxygen Treatments to Reduce Complications in Diabetic Patients Undergoing Vascular Surgery (NCT01002209) | Karolinska Institutet | 2019-10-01 |
| Efficacy and Safety of UGN-101 in Recurrent Patients (NCT04006691) | UroGen Pharma Ltd. | 2019-10-01 |
| The Study for the "Cervical Cancer Screening and Treatment Algorithms Study Using HPV Testing in Africa" (NCT04794660) | International Agency for Research on Cancer | 2019-10-01 |
| Safinamide for Levodopa-induced Dyskinesia (PD-LID) (NCT03987750) | Zambon SpA | 2019-10-01 |
| Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine (NCT04069897) | St. Olavs Hospital | 2019-10-01 |
| Pulsatile High-dose Sunitinib Versus TAS-102 in Patients With Metastatic Colorectal Carcinoma (mCRC) (NCT03909724) | Amsterdam UMC, location VUmc | 2019-10-01 |
| Fixed-dose Combination of Valsartan + Rosuvastatin Versus Their Isolated Components for Hypertension and Dyslipidemia. (NCT02662894) | EMS | 2019-10-01 |
| The Efficacy of Potassium-competitive Acid Blocker in Patients With Laryngopharyngeal Reflux Disease (NCT05871398) | Pusan National University Hospital | 2019-10-01 |
| Effects of tDCS on Heart Rate Variability in Chronic Low Back Pain (NCT04077632) | Universidade Federal do Piauí | 2019-10-01 |
| Granulocyte Colony Stimulating Factor for for the Prevention of Febrile Neutropenia in Epithelial Ovarian Cancer (NCT04101760) | Lei Li | 2019-10-01 |
| Efficacy and Safety of the Biosimilar Natalizumab PB006 in Comparison to Tysabri® (NCT04115488) | Polpharma Biologics S.A. | 2019-10-01 |
| Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer (NCT04288999) | National Cancer Center Hospital East | 2019-10-01 |
| A Phase IIb/III Study of Prof-001 for the Treatment of Patients With Recurrent Vulvovaginal Candidiasis (RVVC) (NCT04734405) | ProFem GmbH | 2019-10-01 |
| Efficacy and Safety of Aflibercept in Patients With Neovascular Age-related Macular Degeneration (NCT05587062) | Cinnagen | 2019-10-01 |
| Decitabine + BUCY vs BUCY Conditioning Regimen for TP53+ Myeloid Tumors Undergoing Allo-HSCT (NCT04123392) | Nanfang Hospital, Southern Medical University | 2019-10-01 |
| Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length (NCT04342585) | National University of Malaysia | 2019-10-01 |
| Enoblituzumab Plus MGA012 or MGD013 in Squamous Cell Carcinoma of the Head and Neck (NCT04129320) | MacroGenics | 2019-10-01 |
| The Evaluation of Vitiligous Lesions Repigmentation After Topical Administration of Methotrexate in Patients With Active Vitiligo (NCT04942860) | Nicolaus Copernicus University | 2019-10-01 |
| The Efficacy of N-acetylcysteine Versus Placebo for the Treatment of Metamphetamine Withdrawal Symptoms (NCT04405193) | Melva Louisa | 2019-10-01 |
| Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy With and Without Bevacizumab as First-Line Treatment of Subjects With Advanced Cervical Cancer (FERMATA) (NCT03912415) | Biocad | 2019-10-01 |
| SUV on 68Ga-DOTATATE PET/CT and Ki-67 Index in Neuro-Endocrine Tumors (NCT02840149) | Jewish General Hospital | 2019-10-01 |
| Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC) (NCT04026113) | AbbVie | 2019-10-01 |
| Impact of DOlutegravir+Lamivudine Simplification on HIV-1 Reservoirs (NCT04034862) | University of Liege | 2019-10-01 |
| An Open-Label Study of DCCR Tablet in Patients With PWS (NCT04086810) | Soleno Therapeutics, Inc. | 2019-10-01 |
| Sequential Nephron Blockade in Acute Heart Failure (NCT04163588) | Policlinico Casilino ASL RMB | 2019-10-01 |
| Drug-eluting Balloon for Treatment of Non-atherosclerotic Renal Artery Stenosis (NCT04366596) | Peking Union Medical College Hospital | 2019-10-01 |
| Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy (NCT04531163) | Al-Azhar University | 2019-10-01 |
| A Research Study Comparing a New Medicine Oral Semaglutide to Placebo in People With Type 2 Diabetes (NCT04109547) | Novo Nordisk A/S | 2019-10-01 |
| Symptomatic Management of Lyme Arthritis (NCT04038346) | Desiree Neville, MD | 2019-10-01 |
| An Extension Study of TS-152 in Subjects With Rheumatoid Arthritis (NCT04077567) | Taisho Pharmaceutical Co., Ltd. | 2019-10-01 |
| Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream (CD06809-41) Versus Vehicle Cream for Actinic Keratosis of the Face (NCT04085367) | Galderma R&D | 2019-09-30 |
| Efficacy, Safety and Tolerability Study of ND0612 vs. Oral Immediate Release Levodopa/Carbidopa (IR-LD/CD) in Subjects With Parkinson's Disease Experiencing Motor Fluctuations (NCT04006210) | NeuroDerm Ltd. | 2019-09-30 |
| Combination Margetuximab, Retifanlimab, Tebotelimab, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/GEJ Cancer (NCT04082364) | MacroGenics | 2019-09-30 |
| A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma (NCT04039607) | Bristol-Myers Squibb | 2019-09-30 |
| CuATSM Compared With Placebo for Treatment of ALS/MND (NCT04082832) | Collaborative Medicinal Development Pty Limited | 2019-09-30 |
| A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME (NCT04108156) | Hoffmann-La Roche | 2019-09-30 |
| Vitamin D 24'000 IU for Oral Intermittent Supplementation (NCT03920150) | University Hospital, Basel, Switzerland | 2019-09-30 |
| Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF) (NCT04075981) | Assistance Publique - Hôpitaux de Paris | 2019-09-30 |
| Novel Triple-dose Tuberculosis Retreatment Regimens: How to Overcome Resistance Without Creating More (NCT03862248) | Institute of Tropical Medicine, Belgium | 2019-09-30 |
| Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer (NCT03362177) | Amgen | 2019-09-30 |
| Study on Clinical Effectiveness of L-Oxiracetam Injection (NCT04205565) | Nanjing Yoko Biomedical Co., Ltd. | 2019-09-30 |
| A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia (NCT04031742) | Innovent Biologics (Suzhou) Co. Ltd. | 2019-09-29 |
| Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense (NCT03974178) | Drugs for Neglected Diseases | 2019-09-29 |
| Aurinia Renal Assessments 2: Aurinia Renal Response in Lupus With Voclosporin (NCT03597464) | Aurinia Pharmaceuticals Inc. | 2019-09-29 |
| Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH (NCT04249336) | Dow University of Health Sciences | 2019-09-27 |
| Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort II) (NCT04090957) | Estetra | 2019-09-27 |
| A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis (NCT04033445) | Janssen Research & Development, LLC | 2019-09-26 |
| Aflibercept for Retinopathy of Prematurity - Intravitreal Injection Versus Laser Therapy (NCT04004208) | Bayer | 2019-09-25 |
| Delafloxacin IV and OS Administration Compared to Best Available Therapy in Patients With Surgical Site Infections (NCT04042077) | Menarini Group | 2019-09-25 |
| Single-dose Vaginal Dinoprostone and Hysterectomy (NCT04080323) | Cairo University | 2019-09-25 |
| Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON) (NCT04005352) | Novartis Pharmaceuticals | 2019-09-25 |
| Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966) (NCT04003636) | Merck Sharp & Dohme LLC | 2019-09-24 |
| Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1) (NCT04146363) | Eli Lilly and Company | 2019-09-24 |
| DPP4-Inhibitors and Bone Metabolism in Diabetes (NCT06770894) | Azienda Policlinico Umberto I | 2019-09-24 |
| First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Persistent Atrial Fibrillation Treatment (RAAFT-3) (NCT04037397) | University of Pennsylvania | 2019-09-24 |
| Risk of SDRs Under 3HP and 1HP Regimen for LTBI (NCT04094012) | National Taiwan University Hospital | 2019-09-24 |
| Prospective Evaluation of Oral Antibiotics for Treatment of Shoulder PJI (NCT04636125) | Rothman Institute Orthopaedics | 2019-09-24 |
| Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy (NCT04090736) | PETHEMA Foundation | 2019-09-24 |
| Research of Unified Protocol for the Treatment of Common Mental Disorders in Adolescents in Hong Kong (NCT04091139) | Chinese University of Hong Kong | 2019-09-24 |
| A Study to Evaluate the Efficacy and Safety of AD-203 (NCT04066530) | Addpharma Inc. | 2019-09-23 |
| A Clinical Study to Evaluate the Efficacy and Safety of Aramchol in Subjects With NASH (ARMOR) (NCT04104321) | Galmed Research and Development, Ltd. | 2019-09-23 |
| Clopidogrel With Aspirin in High-risk Patients With Acute Non-disabling Cerebrovascular Events II (NCT04078737) | Beijing Tiantan Hospital | 2019-09-23 |
| A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension (NCT03683186) | United Therapeutics | 2019-09-23 |
| Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303 (NCT04072835) | Milestone Pharmaceuticals Inc. | 2019-09-23 |
| COrticosteroids in acUte uRticAria in emerGency dEpartment (NCT03545464) | Assistance Publique - Hôpitaux de Paris | 2019-09-21 |
| Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (NCT04095364) | NRG Oncology | 2019-09-20 |
| Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy (NCT04083339) | Applied Therapeutics, Inc. | 2019-09-20 |
| Topical Ruxolitinib Evaluation in Vitiligo Study 1 (TRuE-V1) (NCT04052425) | Incyte Corporation | 2019-09-20 |
| Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC (NCT04066491) | EMD Serono Research & Development Institute, Inc. | 2019-09-20 |
| Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension Trial (NCT03836716) | ZevraDenmark | 2019-09-19 |
| Prospective Study of Benznidazole for Chagas' Disease Children With Chronic Indeterminate Chagas Disease (NCT04024163) | Insud Pharma | 2019-09-19 |
| A Study of Paliperidone Palmitate 6-Month Formulation (NCT04072575) | Janssen Research & Development, LLC | 2019-09-19 |
| Extension Study of Hetrombopag in Severe Aplastic Anemia (NCT04961710) | Jiangsu HengRui Medicine Co., Ltd. | 2019-09-19 |
| Extension Study of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (NCT04103450) | Urovant Sciences GmbH | 2019-09-19 |
| Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention (NCT04040946) | Centre Francois Baclesse | 2019-09-19 |
| A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMS (NCT04121221) | Mapi Pharma Ltd. | 2019-09-19 |
| ADCTA for Adjuvant Immunotherapy in Standard Treatment of Recurrent Glioblastoma Multiforme (GBM) (NCT04277221) | Safe Save Medical Cell Sciences & Technology Co.,Ltd. | 2019-09-19 |
| Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure (NCT04095793) | Theravance Biopharma | 2019-09-19 |
| Improving Maternal heAlth by Reducing Malaria in African HIV Women (NCT03671109) | Barcelona Institute for Global Health | 2019-09-18 |
| A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled 14-week Study of DS-5565 in Chinese Patients With Diabetic Peripheral Neuropathic Pain (NCT04094662) | Daiichi Sankyo Co., Ltd. | 2019-09-18 |
| A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects (NCT03893045) | AMAG Pharmaceuticals, Inc. | 2019-09-18 |
| A Clinical Trial to Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia (NCT04072354) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2019-09-17 |
| DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (NCT03954314) | Population Health Research Institute | 2019-09-17 |
| Lorcaserin and Behavioral Modification for Overweight and Obesity Management in Chinese Obese Patients (NCT03720574) | Kanion & Huawe Medicine Co.,Ltd | 2019-09-17 |
| Safety, Tolerability, and Efficacy of Zilucoplan in Subjects With Generalized Myasthenia Gravis (NCT04115293) | Ra Pharmaceuticals, Inc. | 2019-09-17 |
| Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome (NCT04087421) | University of Aarhus | 2019-09-17 |
| Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients (NCT04008706) | AstraZeneca | 2019-09-17 |
| Safety and Immunogenicity Study of GlaxoSmithKline's Herpes Zoster Subunit Vaccine (HZ/su) When Given on a Two-dose Schedule to Adults at Least 50 Years of Age (YOA) With a Prior Episode of Herpes Zoster (NCT04091451) | GlaxoSmithKline | 2019-09-17 |