| Micronized Purified Flavonoid- Fraction (MPFF) in the Management of Radiation Proctitis (NCT04335617) | Medical University Innsbruck | 2020-02-26 |
| Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer (NCT03937154) | Amgen | 2020-02-26 |
| The SToICAL Study - The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study (NCT04253457) | University Hospital Plymouth NHS Trust | 2020-02-26 |
| Investigational Use of Erenumab for the Treatment of Fibromyalgia Pain (NCT06411067) | United States Naval Medical Center, Portsmouth | 2020-02-26 |
| Spermidine Anti-Hypertension Study (NCT04405388) | Medical University of Graz | 2020-02-25 |
| RCT for Pregabalin in Restless Legs Syndrome in South Korea (NCT04161027) | Seoul National University Hospital | 2020-02-24 |
| NAsal Polyps: Inflammatory & Molecular Phenotyping of Responders to Benralizumab (NCT04185012) | Humanitas Clinical and Research Center | 2020-02-24 |
| Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients (NCT04271917) | University of Tennessee | 2020-02-24 |
| Comparative Efficacy of PRP and Dry Needling in Management of Trigger Points in Masseter Muscle in MPS Patients (NCT04286880) | Postgraduate Institute of Dental Sciences Rohtak | 2020-02-24 |
| Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation (NCT04235140) | Vertex Pharmaceuticals Incorporated | 2020-02-24 |
| Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS (NCT04158674) | Centre Hospitalier Universitaire Dijon | 2020-02-24 |
| Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder (NCT04276883) | BioXcel Therapeutics Inc | 2020-02-24 |
| Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer (NCT04178174) | Centre hospitalier de l'Université de Montréal (CHUM) | 2020-02-23 |
| 16-week Flexible vs. 8-week Semaglutide Titration (NCT04447859) | Tel-Aviv Sourasky Medical Center | 2020-02-23 |
| Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction (NCT04622735) | Unither Pharmaceuticals, France | 2020-02-22 |
| Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin (NCT03820466) | Dr. med. Mahir Karakas | 2020-02-21 |
| Adaptive COVID-19 Treatment Trial (ACTT) (NCT04280705) | National Institute of Allergy and Infectious Diseases (NIAID) | 2020-02-21 |
| EEG Changes in Pediatrics With Language Dysfunction Evaluation of Sleep EEG Changes in Paediatric Patients With Language Dysfunction: A Follow up Study. EEG Changes in Pediatrics With Language Dysfunction (NCT05487521) | Ain Shams University | 2020-02-20 |
| Use of Tranexamic Acid in Blepharoplasties (NCT04724772) | Northwestern University | 2020-02-20 |
| A Trial to Evaluate the Potential Benefit of Adjuvant Chemotherapy for Small Bowel Adenocarcinoma (NCT04257461) | Belgian Group of Digestive Oncology | 2020-02-20 |
| Empagliflozin in Patients With Glomerulonephritis (NCT05283057) | Kasr El Aini Hospital | 2020-02-20 |
| Brazilian Total Neoadjuvant Therapy Trial (NCT05081687) | Hospital Israelita Albert Einstein | 2020-02-20 |
| A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa (NCT04242446) | UCB Biopharma SRL | 2020-02-19 |
| Safety and Diagnostic Efficacy of Mangoral in Participants With Focal Liver Lesions and Reduced Kidney Function (NCT04119843) | Ascelia Pharma AB | 2020-02-19 |
| A Study of Secukinumab Treatment in Patients With Plaque Psoriasis and Coexisting Non-alcoholic Fatty Liver Disease (NAFLD) (NCT04237116) | Novartis Pharmaceuticals | 2020-02-19 |
| Switch to Doravirine/Islatravir (DOR/ISL) in Human Immunodeficiency Virus 1 (HIV-1) Participants Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-018) (NCT04223791) | Merck Sharp & Dohme LLC | 2020-02-18 |
| CAR-T CD19 for Acute Myelogenous Leukemia With t 8:21 and CD19 Expression (NCT04257175) | Sheba Medical Center | 2020-02-18 |
| StrataGraft® Skin Tissue Expanded Access at Specific Study Sites ( StrataCAT ) (NCT04123548) | Stratatech, a Mallinckrodt Company | 2020-02-18 |
| Doravirine Concentrations and Antiviral Activity in Cerebrospinal Fluid in HIV-1 Infected Individuals (NCT04079452) | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 2020-02-18 |
| [KSR-001-P02] Phase 2b/3 Study, Evaluate the Efficacy and Safety of KSR-001 in Patients With Dry Eye Syndrome (NCT05017844) | Kukje Pharma | 2020-02-18 |
| A Study of 2-dose Vaccine Regimen Using 3 Consecutive Lots of Ad26.ZEBOV and MVA-BN-Filo in Adult Participants (NCT04228783) | Janssen Vaccines & Prevention B.V. | 2020-02-18 |
| Safety and Efficacy of a Switch to Doravirine/Islatravir in Participants With HIV-1 (MK-8591A-017) (NCT04223778) | Merck Sharp & Dohme LLC | 2020-02-18 |
| Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older (NCT04183790) | Vertex Pharmaceuticals Incorporated | 2020-02-17 |
| Effectiveness of 0.01% Atropine Sulfate Solution in Controlling of Myopia Progression in Children (NCT04338373) | The V.P. Vyhodcev Eye Hospital | 2020-02-17 |
| A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer (NCT04194944) | Eli Lilly and Company | 2020-02-17 |
| Optimizing Tobacco Use Treatment for PLWHA (NCT04176172) | University of Pennsylvania | 2020-02-17 |
| Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients (NCT04191213) | Al-Neelain University | 2020-02-15 |
| Ciprofloxacin Versus an Aminoglycoside Followed by Ciprofloxacin for Bubonic Plague (NCT04110340) | University of Oxford | 2020-02-15 |
| Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients (NCT04214990) | National Cancer Center, Korea | 2020-02-15 |
| HA-WBRT vs SRS in Patients With Multiple Brain Metastases (NCT04277403) | Medical University Innsbruck | 2020-02-15 |
| Feasibility of a Clinical Trial Comparing the Use of Cetirizine to Replace Diphenhydramine in the Prevention of Reactions Related to Paclitaxel (NCT04237090) | Ciusss de L'Est de l'Île de Montréal | 2020-02-14 |
| Long-term Safety and Efficacy Study of MND-2119 in Patients With Hypertriglyceridemia (NCT04221217) | Mochida Pharmaceutical Company, Ltd. | 2020-02-14 |
| Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass (NCT04217421) | dr. M.J.N.L. Benders | 2020-02-14 |
| A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease (NCT04293185) | Genetix Biotherapeutics Inc. | 2020-02-14 |
| Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301) (NCT04248829) | Yuhan Corporation | 2020-02-13 |
| ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD (NCT03911505) | Amicus Therapeutics | 2020-02-13 |
| Exemestane in Hormone Receptor Positive High Grade Ovarian Cancer (NCT04460807) | Ente Ospedaliero Ospedali Galliera | 2020-02-13 |
| 3,3'-Dioxo-2,2'-Bisindolylidene-5,5'-Disulfonate Disodium 0.8% Solution as an Aid for Ureteral Patency (NCT04228445) | Prove pharm | 2020-02-13 |
| Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991) (NCT04191096) | Merck Sharp & Dohme LLC | 2020-02-12 |
| Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis (NCT04286607) | Arcutis Biotherapeutics, Inc. | 2020-02-12 |
| Phase 3 Study of SNF472 for Calciphylaxis (NCT04195906) | Sanifit Therapeutics S. A. | 2020-02-12 |
| Study to Evaluate the Efficacy and Safety of RPH-104 Treatment in Patients With Idiopathic Recurrent Pericarditis (NCT04692766) | R-Pharm International, LLC | 2020-02-12 |
| A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA) (NCT04088396) | Eli Lilly and Company | 2020-02-12 |
| Topical 0.01% Atropine for the Control of Fast Progressing Myopia (NCT04173780) | University Hospital, Strasbourg, France | 2020-02-12 |
| A Trial of Remdesivir in Adults With Mild and Moderate COVID-19 (NCT04252664) | Capital Medical University | 2020-02-12 |
| Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality (NCT03594175) | Chiesi Farmaceutici S.p.A. | 2020-02-12 |
| Roflumilast or Azithromycin to Prevent COPD Exacerbations Trial (NCT04069312) | Johns Hopkins University | 2020-02-11 |
| Study to Assess the Safety and Efficacy of Lebrikizumab (LY3650150) in Adolescent Participants With Moderate-to-Severe Atopic Dermatitis (NCT04250350) | Eli Lilly and Company | 2020-02-11 |
| A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer (NCT04211337) | Loxo Oncology, Inc. | 2020-02-11 |
| Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances (NCT04218110) | Professional Disposables International, Inc. | 2020-02-11 |
| Head-of-Bed Positioning in Large Artery Acute Ischemic Stroke (NCT05073159) | National University of Singapore | 2020-02-11 |
| Diaphragmatic Paralysis Comparison Between Local Anesthetic Volumen Doses After Interscalene Block (NCT04385966) | Instituto de Investigación Sanitaria Aragón | 2020-02-11 |
| Myo-inositol for the Management of Poor Ovarian Responders: A Prospective Randomized Controlled Trial (NCT04273256) | American University of Beirut Medical Center | 2020-02-11 |
| A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment (NCT04083235) | Ipsen | 2020-02-11 |
| Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination (NCT04247074) | Galderma R&D | 2020-02-10 |
| Long-term Follow-up Study of Patients Receiving Onasemnogene Abeparvovec-xioi (NCT04042025) | Novartis Gene Therapies | 2020-02-10 |
| Clinical Extension Study for Safety and Efficacy Evaluation of Cellavita-HD Administration in Huntington's Patients. (NCT04219241) | Azidus Brasil | 2020-02-10 |
| Impact of Topical Antiadhesion Therapy on Wound Healing and Postoperative Pain After Anal Surgery (NCT04275596) | Mansoura University | 2020-02-10 |
| Treatment of Moderate to Severe Glabellar Lines (NCT04249583) | Galderma R&D | 2020-02-10 |
| Protective Effect of Aspirin on COVID-19 Patients (NCT04365309) | Xijing Hospital | 2020-02-10 |
| A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Emicizumab in Participants With Mild or Moderate Hemophilia A Without FVIII Inhibitors (NCT04158648) | Hoffmann-La Roche | 2020-02-10 |
| The Effect of Chemoradiotherapy in Patients With Refractory Pituitary Adenomas (NCT04244708) | Peking Union Medical College Hospital | 2020-02-10 |
| The Efficacy of Intravenous Immunoglobulin Therapy for Severe 2019-nCoV Infected Pneumonia (NCT04261426) | Peking Union Medical College Hospital | 2020-02-10 |
| Treatment of Moderate to Severe Lateral Canthal Lines (NCT04249687) | Galderma R&D | 2020-02-10 |
| The Objectives of This Study Are Comparative Assessment of the Tolerability, Safety and Immunogenicity of the Flu-M Vaccine vs. the Ultrix® Vaccine by Single Vaccination of Children Aged 6 to 17 Years. (NCT05317767) | St. Petersburg Research Institute of Vaccines and Sera | 2020-02-10 |
| A Pilot Study of Sildenafil in COVID-19 (NCT04304313) | Tongji Hospital | 2020-02-09 |
| The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 ) (NCT03999580) | Jantchou Prevost | 2020-02-07 |
| A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM) (NCT04173494) | Sierra Oncology LLC - a GSK company | 2020-02-07 |
| A Study to Evaluate the Safety and Efficacy of Polatuzumab Vedotin in Combination With Rituximab, Gemcitabine and Oxaliplatin Compared to Rituximab, Gemcitabine and Oxaliplatin Alone in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (NCT04182204) | Hoffmann-La Roche | 2020-02-07 |
| A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer (NCT04100018) | Bristol-Myers Squibb | 2020-02-06 |
| SAR408701 Versus Docetaxel in Previously Treated, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small-cell Lung Cancer Patients (NCT04154956) | Sanofi | 2020-02-06 |
| Efficacy and Safety of Hydroxychloroquine for Treatment of COVID-19 (NCT04261517) | Shanghai Public Health Clinical Center | 2020-02-06 |
| A Trial of Remdesivir in Adults With Severe COVID-19 (NCT04257656) | Capital Medical University | 2020-02-06 |
| A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer (NCT04209114) | Bristol-Myers Squibb | 2020-02-05 |
| A Two-Arm Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Chinese Participants With HER2-Positive Early Breast Cancer (NCT04024462) | Hoffmann-La Roche | 2020-02-05 |
| Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to Ocrelizumab (NCT04175834) | Providence Health & Services | 2020-02-05 |
| A RCT Comparing Dronabinol to a Placebo for Post-operative Pain in Total Joint Arthroplasty (NCT04298528) | Colorado Joint Replacement | 2020-02-05 |
| A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010) (KEYNOTE-010) (NCT04199104) | Merck Sharp & Dohme LLC | 2020-02-05 |
| Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes (NCT04218123) | Medical University of South Carolina | 2020-02-05 |
| Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO (NCT03841734) | Centre Hospitalier Universitaire de Nice | 2020-02-04 |
| A Study to Test if TEV-50717 is Safe and Effective in Relieving Abnormal Involuntary Movements in Cerebral Palsy (NCT04200352) | Teva Branded Pharmaceutical Products R&D, Inc. | 2020-02-04 |
| A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer (NCT04256421) | Hoffmann-La Roche | 2020-02-04 |
| Immune Equivalence Between Multi-dose and Single Dose Formulation of Vi-DT and Their Overall Safety (Phase III) (NCT04204096) | International Vaccine Institute | 2020-02-04 |
| A Study to Evaluate the Efficacy and Safety of Upadacitinib in Participants With Takayasu Arteritis (TAK) (NCT04161898) | AbbVie | 2020-02-04 |
| A Study to Evaluate the Efficacy and Safety of Pirfenidone With Novel Coronavirus Infection (NCT04282902) | Huilan Zhang | 2020-02-04 |
| Opioid-free Anesthesia for Open Cardiac Surgery: A Prospective Randomized Controlled Trial (NCT04197570) | Benaroya Research Institute | 2020-02-04 |
| Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease (NCT04142125) | Population Health Research Institute | 2020-02-03 |
| An Extension Study of Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer (NCT04151719) | Bausch Health Americas, Inc. | 2020-02-03 |
| Rituximab and Ibrutinib (RI) Versus Dexamethasone, Rituximab and Cyclophosphamide (DRC) as Initial Therapy for Waldenström's Macroglobulinaemia (NCT04061512) | University College, London | 2020-02-03 |
| Mirabegron And Ureteral Stent-related Pain (MAP) Trial (NCT04286152) | Unity Health Toronto | 2020-02-03 |