| Efficacy of Intravenous Almitrine in Reducing the Need for Mechanical Ventilation in Patients With Hypoxemic Acute Respiratory Failure Due to Covid-19-related Pneumonia (NCT04357457) | Assistance Publique - Hôpitaux de Paris | 2020-09-03 |
| Multimodal Biomarkers for Diagnosis and Prognosis in VCI (NCT04604600) | National Taiwan University Hospital | 2020-09-03 |
| Plasma Rich in Growth Factors in the Preservation of the Alveolar Ridge After Simple Molar Tooth Extractions. (NCT04945629) | Fundación Eduardo Anitua | 2020-09-02 |
| TWICE-IRI: Optimization of Second-line Therapy With Aflibercept, Irinotecan (Day 1 or Day 1,3), 5-Fluorouracile and Folinic Acid in Patients With Metastatic Colorectal Cancer. A Randomized Phase III Study. (NCT04392479) | Hôpital Franco-Britannique-Fondation Cognacq-Jay | 2020-09-02 |
| Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease (NCT04152837) | Palladio Biosciences | 2020-09-02 |
| Adjuvant Therapy With Abemaciclib + SOC ET vs. SOC ET in Clinical or Genomic High Risk, HR+/HER2- EBC (NCT04565054) | Women's Cancer Study Group GmbH | 2020-09-02 |
| A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral Immunodeficiency (NCT04561115) | Grifols Therapeutics LLC | 2020-09-02 |
| A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2) (NCT04077437) | Resilient Pharmaceuticals | 2020-09-02 |
| Clinical Outcome and Future Liver Remnant Regenerative Response in Laparoscopic Versus Open ALPPS (NCT04868149) | The University of Hong Kong | 2020-09-02 |
| A Hepatitis B Vaccine Challenge Study After Previous Vaxelis® Vaccination (V419-013) (NCT04490499) | Merck Sharp & Dohme LLC | 2020-09-02 |
| Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial (NCT04534075) | Sahlgrenska University Hospital | 2020-09-02 |
| AZD1222 Vaccine for the Prevention of COVID-19 (NCT04540393) | AstraZeneca | 2020-09-02 |
| Convalescent Plasma (PC) and Human Intravenous Anti-COVID-19 Immunoglobulin (IV Anti COVID-19 IgG) in Patients Hospitalized for COVID-19. (NCT04395170) | Lifefactors Zona Franca, SAS | 2020-09-01 |
| Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma (NCT04396860) | National Cancer Institute (NCI) | 2020-09-01 |
| Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE) (NCT04394351) | Regeneron Pharmaceuticals | 2020-09-01 |
| Cystadrops in Pediatric Cystinosis Patients From Six Months to Less Than Two Years Old (SCOB2) (NCT04125927) | RECORDATI GROUP | 2020-09-01 |
| A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. (NCT03923725) | University of Oxford | 2020-09-01 |
| Anti-inflammatory/Antioxidant Oral Nutrition Supplementation in COVID-19 (NCT04323228) | King Saud University | 2020-09-01 |
| Ranibizumab Vs Bevacizumab for Type 1 Retinopathy of Prematurity (NCT05033106) | Zagazig University | 2020-09-01 |
| Cetuximab Re-challenge for Colorectal Cancer Liver Metastasis (NCT04509635) | Fudan University | 2020-09-01 |
| A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies (NCT04547049) | First Affiliated Hospital of Zhejiang University | 2020-09-01 |
| Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS) (NCT04717037) | King Abdullah International Medical Research Center | 2020-09-01 |
| Postoperative Antimicrobial Prophylaxis Versus Placebo for Infection Prevention in HCC After Liver Resection (NCT03990974) | Sun Yat-sen University | 2020-09-01 |
| Prevention of COVID19 Infection in Nursing Homes by Chemoprophylaxis With Hydroxychloroquine (PREVICHARM) (NCT04400019) | University of Malaga | 2020-09-01 |
| Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs (NCT04271189) | Azienda Ospedaliero-Universitaria di Parma | 2020-09-01 |
| Pradefovir Treatment for the Patients With Chronic Hepatitis B Virus Infections: a Phase3 Study (NCT04543565) | Xi'an Xintong Pharmaceutical Research Co.,Ltd. | 2020-09-01 |
| A Phase 3 Molluscum Contagiosum Efficacy and Safety Study (NCT04535531) | Novan, Inc. | 2020-09-01 |
| Topical Analgesia Post-Haemorrhoidectomy (NCT04276298) | University of Auckland, New Zealand | 2020-09-01 |
| Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section (NCT04780412) | Ain Shams University | 2020-09-01 |
| Megestrol Acetate Plus Rosuvastatin in Young Women With Atypical Endometrial Hyperplasia (NCT04491682) | Fudan University | 2020-09-01 |
| Treatment Shortening of Drug-Sensitive Pulmonary Tuberculosis Using High Dose Rifampicin (Hi-DoRi-3) (NCT04485156) | Seoul National University Hospital | 2020-09-01 |
| PSMA-PET Guided Hypofractionated Salvage Prostate Bed Radiotherapy (NCT04642027) | University Medical Center Groningen | 2020-09-01 |
| Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer (NCT04230187) | Yanhong Deng | 2020-09-01 |
| Progestin Primed Double Stimulation Protocol Versus Flexible GnRH Antagonist Protocol in Poor Responders (NCT04537078) | El Shatby University Hospital for Obstetrics and Gynecology | 2020-09-01 |
| Study of Azacytidine Combined With Lenalidomide As Maintenance Therapy Based on MRD Monitoring in AML (NCT04490707) | Ge Zheng | 2020-09-01 |
| Safety and Immunogenicity of 20vPnC Coadministered With SIIV in Adults ≥65 Years of Age (NCT04526574) | Pfizer | 2020-09-01 |
| Evaluation of Aesthetic Surgical Wound Closure by a Single Layer in Comparison With Traditional Multi-layer Closure (NCT05166681) | Abouqir General Hospital | 2020-09-01 |
| Intravitreal Bevacizumab for Nonproliferative Diabetic Retinopathy (NCT04511715) | Shahid Beheshti University of Medical Sciences | 2020-09-01 |
| Azithromycin-Prevention in Labor Use Study (A-PLUS) (NCT03871491) | NICHD Global Network for Women's and Children's Health | 2020-09-01 |
| A Clinical Trial of Two Adjuvant Chemotherapy Regimens for Postoperative Gastric Cancer (NCT04351867) | LiNing | 2020-09-01 |
| Gardasil Versus Cervarix in the Treatment of Warts (NCT05383625) | Zagazig University | 2020-09-01 |
| PROphylaxis for paTiEnts at Risk of COVID-19 infecTion (NCT04389359) | Cambridge University Hospitals NHS Foundation Trust | 2020-09-01 |
| CT-P13 (Infliximab) Subcutaneous Administration in Patients With Moderately to Severely Active Ulcerative Colitis (LIBERTY-UC) (NCT04205643) | Celltrion | 2020-09-01 |
| Efficacy and Safety of CRT, Durvalumab and Surgery for SST (NCT04465968) | National Cancer Center Hospital East | 2020-09-01 |
| Concurrent and Adjuvant PD1 Treatment Combined With Chemo-radiotherapy for High-risk Nasopharyngeal Carcinoma (NCT04453826) | Sun Yat-sen University | 2020-09-01 |
| A Trial Using ANAKINRA, TOCILIZUMAB Alone or in Association With RUXOLITINIB in Severe Stage 2b and 3 of COVID19-associated Disease (NCT04424056) | Assistance Publique Hopitaux De Marseille | 2020-09-01 |
| Preoperative Nutrition for Crohn's Disease Patients (NCT04398836) | Tel-Aviv Sourasky Medical Center | 2020-09-01 |
| Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer Pain (NCT04533243) | Fujian Cancer Hospital | 2020-09-01 |
| Efficacy and Safety of Slenyto for Insomnia in Children With ASD (NCT04233502) | Neurim Pharmaceuticals Ltd. | 2020-09-01 |
| Mini-invasive Preventive Fixation of the Contralateral Femoral Neck in Patients Operated on for a Femoral Neck Fracture (NCT04408053) | Assistance Publique - Hôpitaux de Paris | 2020-09-01 |
| Probiotics in Pediatric Chronic Cholestasis (NCT04787419) | Indonesia University | 2020-09-01 |
| VALO-2: Study Evaluating the Safety and Efficacy of PTX022 in the Treatment of Adults With Pachyonychia Congenita (NCT04520750) | Palvella Therapeutics, Inc. | 2020-09-01 |
| Hemoglobin Maintenance in Pediatric ESRD (End-stage Renal Disease) Patients by Ferric Pyrophosphate Citrate (FPC) (NCT04239391) | Rockwell Medical Technologies, Inc. | 2020-09-01 |
| A Stepped Care Approach to Treating Tobacco Use in Rural Veterans (NCT04501016) | Iowa City Veterans Affairs Medical Center | 2020-09-01 |
| CNI Transient Replacement by Belatacept From 3 to 12 Months Post Transplantation in Patients With Early Graft Dysfunction (NCT04013620) | Nantes University Hospital | 2020-09-01 |
| Short Course Rifapentine and Isoniazid for the Preventive Treatment for Latent Genital Tuberculosis (NCT04528277) | Huashan Hospital | 2020-09-01 |
| Post Exposure Prophylaxis in Healthcare Workers Exposed to COVID-19 Patients (NCT04437693) | Hamad Medical Corporation | 2020-08-31 |
| Additional Screening With Sensitives RDTs and Malaria (NCT04147546) | Institut de Recherche en Sciences de la Sante, Burkina Faso | 2020-08-31 |
| Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet Versus Best Available Therapy to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis (NCT04468984) | AbbVie | 2020-08-31 |
| A Study to Evaluate the Efficacy of Xlear vs. Placebo for Acute COVID-19 Infection (NCT04858620) | Larkin Community Hospital | 2020-08-30 |
| Daily Regimen of Tenofovir/Emtricitabine as Prevention for COVID-19 in Health Care Personnel in Colombia (NCT04519125) | Hospital Universitario San Ignacio | 2020-08-30 |
| Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults (NCT04516746) | AstraZeneca | 2020-08-28 |
| Losmapimod Safety and Efficacy in COVID-19 (NCT04511819) | Fulcrum Therapeutics | 2020-08-28 |
| Cryoablation in Combination (or Not) With Pembrolizumab and Pemetrexed-carboplatin in 1st-line Treatment for Patients With Metastatic Lung Adenocarcinoma (NCT04339218) | Institut Bergonié | 2020-08-28 |
| GnRH Therapy on Cognition in Down Syndrome (NCT04390646) | Nelly Pitteloud | 2020-08-27 |
| The Relapse from MRD Negativity As Indication for Treatment (REMNANT) Study (NCT04513639) | Oslo University Hospital | 2020-08-27 |
| Catalysing the Containment of COVID-19 (NCT04523090) | University of Cape Town | 2020-08-27 |
| The Effect of Dexamethasone 12 mg vs 6 mg on Thromboembolic Events in Patients With Critical COVID-19 (NCT05195242) | Karolinska Institutet | 2020-08-27 |
| Higher vs. Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia (NCT04509973) | Scandinavian Critical Care Trials Group | 2020-08-27 |
| VIR-7831 for the Early Treatment of COVID-19 in Outpatients (NCT04545060) | Vir Biotechnology, Inc. | 2020-08-27 |
| Efficacy and Safety of BIO101 in the Prevention of Respiratory Deterioration in Hospitalized COVID-19 Patients (NCT04472728) | Biophytis | 2020-08-26 |
| The IPLA-OVCA Trial, Intra-Peritoneal Local Anaesthetics in Ovarian Cancer (NCT04065009) | Karolinska Institutet | 2020-08-26 |
| Immunogenicity and Safety of Concomitant and Non-Concomitant Administration of RotaTeq® (V260) and Inactivated Poliomyelitis Vaccine in Healthy Chinese Infants (V260-074) (NCT04481191) | Merck Sharp & Dohme LLC | 2020-08-25 |
| Study to Assess the Safety and Immunogenicity of GSK Meningococcal Group B Vaccine When Administered Concomitantly With GSK Meningococcal MenACWY Conjugate Vaccine in Healthy Subjects of 16-18 Years of Age (NCT04318548) | GlaxoSmithKline | 2020-08-25 |
| A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule Versus Sunitinib in Subjects With Advanced Renal Cancer (NCT04523272) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2020-08-25 |
| Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery (NCT04498117) | CanariaBio Inc. | 2020-08-25 |
| Safety and Efficacy of Convalescent Plasma Transfusion for Patients With COVID-19 (NCT04388410) | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 2020-08-25 |
| Dapagliflozin in Physical Exercise in Type 1 Diabetes (NCT04049110) | Insel Gruppe AG, University Hospital Bern | 2020-08-25 |
| Combination of Ranibizumab and Targeted Laser Photocoagulation (NCT04444492) | University of Giessen | 2020-08-25 |
| A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista (NCT04487067) | Hoffmann-La Roche | 2020-08-25 |
| Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (NCT04102371) | Children's Hospital of Philadelphia | 2020-08-25 |
| Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance (NCT04285086) | PharmaEssentia | 2020-08-25 |
| A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the Knee (NCT04520607) | Biosplice Therapeutics, Inc. | 2020-08-25 |
| A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES) (NCT04504825) | Alexion Pharmaceuticals, Inc. | 2020-08-25 |
| Spondyloarthritis: Inducing Drug-free Remission by Early TNF-alpha Blockade (NCT04435288) | University Hospital, Ghent | 2020-08-24 |
| A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC) (NCT04513925) | Hoffmann-La Roche | 2020-08-24 |
| Reducing Acute Severe Respiratory Events in Health Care Workers During the Covid-19 Pandemic With OM85 (NCT04496245) | The University of Queensland | 2020-08-24 |
| Rivaroxaban Plus ASA in Embolic Stroke of Undetermined Source(AREST-ESUS) (NCT04273516) | Mazandaran University of Medical Sciences | 2020-08-22 |
| Clinical Trial Evaluating the Efficacy and Safety of Favipiravir in Moderate to Severe COVID-19 Patients (NCT04529499) | Dr. Reddy's Laboratories Limited | 2020-08-22 |
| Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars (NCT05573425) | Jinnah Postgraduate Medical Centre | 2020-08-22 |
| Study to Evaluate Oral Ubrogepant in the Acute Treatment of Migraine During the Prodrome in Adult Participants (NCT04492020) | AbbVie | 2020-08-21 |
| A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias. (NCT04134845) | Vanderbilt University Medical Center | 2020-08-21 |
| A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (NCT04338321) | Janssen-Cilag International NV | 2020-08-21 |
| Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia (NCT04467840) | RedHill Biopharma Limited | 2020-08-21 |
| Moxidectin for LF, Cote d'Ivoire (DOLF) (NCT04410406) | Washington University School of Medicine | 2020-08-20 |
| Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL (NCT04404283) | Seagen, a wholly owned subsidiary of Pfizer | 2020-08-20 |
| Composite Steep-pulseTreatment Device Used in Patients With Benign Prostatic Hyperplasia (NCT05531344) | REMD Medical Technology | 2020-08-20 |
| Study to Evaluate the Efficacy and Safety of Toripalimab in Combination With Axitinib Versus Sunitinib Monotherapy in Advanced Renal Cell Cancer (NCT04394975) | Shanghai Junshi Bioscience Co., Ltd. | 2020-08-20 |
| Efficacy and Safety of Olaparib (MK-7339) With or Without Bevacizumab Compared to Bevacizumab With a Fluoropyrimidine in Unresectable or Metastatic Colorectal Cancer (CRC) (MK-7339-003/LYNK-003) (NCT04456699) | Merck Sharp & Dohme LLC | 2020-08-19 |
| Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Colds Due to Enterovirus/Rhinovirus Infection (NCT04489381) | Romark Laboratories L.C. | 2020-08-19 |