| Safety and Efficacy of FURESTEM-AD Inj. for Moderate to Severe Atopic Dermatitis (AD) (NCT05004324) | Kang Stem Biotech Co., Ltd. | 2021-06-29 |
| Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study (NCT04887870) | Mirati Therapeutics Inc. | 2021-06-29 |
| Influence of PRGF (Plasma Rich in Growth Factors) Puncture in Ovaries With Low Follicular Reservetechniques (NCT02992756) | IVI Bilbao | 2021-06-29 |
| Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection (NCT04925752) | Gilead Sciences | 2021-06-28 |
| Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease (NCT04915755) | GlaxoSmithKline | 2021-06-28 |
| AERIAL Trial: Antiplatelet Therapy in Heart Transplantation (NCT04770012) | Ottawa Heart Institute Research Corporation | 2021-06-28 |
| Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer (NCT04579224) | National Cancer Institute (NCI) | 2021-06-28 |
| Phase III Clinical Trial of Y-2 Sublingual Tablets in the Treatment of Acute Ischemic Stroke (NCT04950920) | Peking University Third Hospital | 2021-06-28 |
| A Single Center, Randomized, Open Label, Parallel Group, Phase 3 Study to Evaluate the Efficacy of Dapagliflozin in Subjects With Nonalcoholic Fatty Liver Disease (NCT05308160) | National Taiwan University Hospital | 2021-06-28 |
| OptiMATe: De-escalated Induction Treatment in Primary CNS Lymphoma (NCT04931368) | Klinikum Stuttgart | 2021-06-28 |
| Phase II/III Study of AZD2816, for the Prevention of COVID-19 in Adults (NCT04973449) | AstraZeneca | 2021-06-27 |
| A Study to Assess the Efficacy and Safety of XC221 in Patients With Mild COVID-19 (NCT04940182) | RSV Therapeutics LLC | 2021-06-26 |
| ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple Sclerosis (NCT04695080) | Queen Mary University of London | 2021-06-25 |
| Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Participants With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study) (NCT04806451) | Neurocrine Biosciences | 2021-06-25 |
| Mother's Recorded Voice Versus Dexmedetomidine on Postoperative Agitation (NCT04941508) | Assiut University | 2021-06-25 |
| MTX and Steroid as First-line Therapy for aGVHD (NCT04960644) | Peking University People's Hospital | 2021-06-25 |
| A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy (NCT04629248) | Hoffmann-La Roche | 2021-06-25 |
| Effect of Trimetazidine on Radiotherapy-induced Heart Damage. (NCT04939857) | Peking University Third Hospital | 2021-06-25 |
| A Randomized Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE) (NCT04929249) | Novartis Pharmaceuticals | 2021-06-25 |
| Regional Anesthesia in Pediatric Orthopaedic Patients (NCT04669145) | Ochsner Health System | 2021-06-24 |
| Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment (NCT04829539) | University of Rochester NCORP Research Base | 2021-06-24 |
| Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort) (NCT05171816) | AstraZeneca | 2021-06-24 |
| Study of Efficacy and Safety of Secukinumab in Chinese Subjects With Active PsA Compared to Placebo. (NCT04711902) | Novartis Pharmaceuticals | 2021-06-24 |
| The Phase III Clinical Trial of X842 Capsules for Reflux Esophagitis (NCT07079540) | Jiangsu Sinorda Biomedicine Co., Ltd | 2021-06-24 |
| Naldebain for Pain Control After Bariatric Surgery (NCT04651361) | E-DA Hospital | 2021-06-24 |
| Efficacy Evaluation of VERU-111 for mCRPC in Patients Who Have Failed at Least One Androgen Receptor Targeting Agent (NCT04844749) | Veru Inc. | 2021-06-24 |
| Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome (NCT04873934) | Novartis Pharmaceuticals | 2021-06-24 |
| Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea (NCT04801771) | Inspire Medical Systems, Inc. | 2021-06-24 |
| Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study (NCT04600921) | Medical University of Graz | 2021-06-24 |
| Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10) (NCT04793958) | Mirati Therapeutics Inc. | 2021-06-24 |
| A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) (NCT04964089) | Kodiak Sciences Inc | 2021-06-23 |
| Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo (NCT05144217) | Prof. Dr. Frank Behrens | 2021-06-23 |
| De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA) (NCT04852887) | NRG Oncology | 2021-06-23 |
| A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity (NCT04915729) | Boehringer Ingelheim | 2021-06-22 |
| A Clinical Studyf of SHR-1701 or Placebo in Combination With BP102 and XELOX in the First-line Treatment of mCRC (NCT04856787) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2021-06-22 |
| Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy (NCT04785443) | University Hospital, Brest | 2021-06-22 |
| A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer (NCT04739761) | AstraZeneca | 2021-06-22 |
| Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment. (NCT04765020) | Universität Duisburg-Essen | 2021-06-21 |
| Dual Therapy in HIV Patients in 4 Days a Week Versus 7 Days a Week (NCT04867083) | ANRS, Emerging Infectious Diseases | 2021-06-21 |
| 24 Hours Treatment with Alteplase in Patients with Ischemic Stroke (NCT04879615) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2021-06-21 |
| Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial (NCT04839354) | Claudia R. Morris | 2021-06-21 |
| Antaitavir Hasophate Capsules Combined With Yiqibuvir Tablets in Treatment Adult Patients With Chronic Hepatitis C (NCT05395416) | Sunshine Lake Pharma Co., Ltd. | 2021-06-21 |
| Efficacy, Immunogenicity, and Safety of the Inactivated COVID-19 Vaccine (TURKOVAC) Versus the CoronaVac Vaccine (NCT04942405) | Health Institutes of Turkey | 2021-06-21 |
| Perioperative Patient Skin Antiseptic Preparation Evaluation (NCT04756804) | Zurex Pharma, Inc. | 2021-06-21 |
| Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography (NCT05998525) | Hilda Elizabeth Macías Cervantes | 2021-06-21 |
| Cefixime Clinical Trial (NCT04958122) | University of Southern California | 2021-06-20 |
| A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation (NCT04928391) | Assiut University | 2021-06-20 |
| Evaluation of The Effect of Rutin and Vitamin C on the Oxidative Stress in Hemodialysis Patients (NCT04955145) | Ain Shams University | 2021-06-20 |
| A Study to Evaluate Dose Levels of Ad26.COV2.S Administered as a Two-dose Schedule in Healthy Adults (NCT04908722) | Janssen Vaccines & Prevention B.V. | 2021-06-18 |
| Study Evaluating the Efficacy and Safety of Dose Conversion From a Long-acting Erythropoiesis-stimulating Agent (Mircera®) to Three Times Weekly Oral Vadadustat for the Maintenance Treatment of Anemia in Hemodialysis Subjects (NCT04707768) | Akebia Therapeutics | 2021-06-18 |
| Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49) (NCT04895358) | Merck Sharp & Dohme LLC | 2021-06-18 |
| Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA (NCT04597008) | Major Extremity Trauma Research Consortium | 2021-06-18 |
| Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients (NCT04757337) | UNICANCER | 2021-06-18 |
| Apomorphine in Severe Brain-injured Patients (NCT05213169) | University of Liege | 2021-06-18 |
| Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy (NCT04912843) | Wuhan Neurophth Biotechnology Limited Company | 2021-06-18 |
| A Study of Guselkumab in Participants With Active Psoriatic Arthritis (NCT04882098) | Janssen Research & Development, LLC | 2021-06-17 |
| A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation (NCT04947553) | Axsome Therapeutics, Inc. | 2021-06-17 |
| A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (cCRT) in Participants With Stage III Unresectable Non-Small Cell Lung Cancer (NCT04866017) | BeiGene | 2021-06-17 |
| Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial) (NCT04741880) | Instituto Nacional de Cancer, Brazil | 2021-06-17 |
| A Phase 3 Study to Compare Between CT-P41 and US-licensed Prolia in Postmenopausal Women With Osteoporosis (NCT04757376) | Celltrion | 2021-06-17 |
| A Study to Test Whether BI 767551 Can Prevent COVID-19 in People Who Have Been Exposed to SARS-CoV-2 (NCT04894474) | Boehringer Ingelheim | 2021-06-17 |
| A Study to Evaluate the Efficacy, Pharmacodynamics, Safety, and Immunogenicity of FKS518 in Postmenopausal Women With Osteoporosis (NCT04934072) | Fresenius Kabi SwissBioSim GmbH | 2021-06-16 |
| To Evaluate Reduction of Pain in Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo. (NCT03676556) | Hospital Universitari de Bellvitge | 2021-06-16 |
| Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial (NCT04881825) | Zealand Pharma | 2021-06-16 |
| Feasibility of Use of Indocyanine Green in Pediatric Colorectal Surgery (NCT04904081) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-06-16 |
| Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole (NCT04965298) | Norfolk and Norwich University Hospitals NHS Foundation Trust | 2021-06-16 |
| Efficacy of Low-dose Interleukin-2 Treatment in Chronic Spontaneous Urticaria (NCT04893980) | Second Xiangya Hospital of Central South University | 2021-06-16 |
| Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes (NCT04916470) | Novo Nordisk A/S | 2021-06-15 |
| A Global Phase III Clinical Trial of Recombinant COVID- 19 Vaccine (Sf9 Cells) (NCT04904471) | WestVac Biopharma Co., Ltd. | 2021-06-15 |
| The DAWN Antivirals Trial for Ambulatory COVID-19 Patients (NCT04730206) | KU Leuven | 2021-06-15 |
| Efficacy and Safety of MOX/ALB Co-administration (NCT04726969) | Jennifer Keiser | 2021-06-15 |
| A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout (NCT04956432) | Jiangsu HengRui Medicine Co., Ltd. | 2021-06-15 |
| Comparative Evaluation of the McGrath Videolaryngoscope and the Direct Laryngoscopy for Tracheal Intubation in the Prehospital Setting (NCT04930419) | Assistance Publique - Hôpitaux de Paris | 2021-06-15 |
| Study of Camrelizumab Plus Chemotherapy as Neoadjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (NCT04907344) | Tianjin Medical University Cancer Institute and Hospital | 2021-06-15 |
| Traditional Chinese Medicine Herbs in the Freeze-all IVF Cycle (NCT04935073) | Peking University Third Hospital | 2021-06-15 |
| The Effectiveness of Spermotrend Food Supplement in the Treatment of Male Infertility (NCT05222841) | Catalysis SL | 2021-06-15 |
| Effects of Acute Long-acting Bronchodilation on Oxygenation and Peripheral Ventilation in COPD (NCT05927155) | Erasme University Hospital | 2021-06-15 |
| 177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer (NCT04689828) | Novartis Pharmaceuticals | 2021-06-15 |
| Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis Trial (NCT04942002) | Asociación para Evitar la Ceguera en México | 2021-06-15 |
| Efficacy and Safety Evaluation for the Treatment of Allergy Against Grass and Olive Pollen (NCT04891237) | Inmunotek S.L. | 2021-06-14 |
| Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (NCT04780932) | Assistance Publique - Hôpitaux de Paris | 2021-06-14 |
| Nasal Gel for the Prevention of Nausea and Vomiting Associated With Motion (NCT04947423) | Repurposed Therapeutics, Inc. | 2021-06-14 |
| Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study (NCT05554822) | Azienda Ospedaliero Universitaria Maggiore della Carita | 2021-06-14 |
| Using Vitamin D to Reduce Oral Mucosal Inflammation in Chemotherapy Patients With Oral Squamous Cell Carcinoma (NCT06016400) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2021-06-14 |
| A Mobile Application to Promote Self-management and Improve Outcomes in Heart Failure (NCT04755816) | University of Michigan | 2021-06-14 |
| FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS) (NCT04768972) | Ionis Pharmaceuticals, Inc. | 2021-06-14 |
| Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition (NCT05051163) | Makerere University | 2021-06-14 |
| Efficacy and Safety of GMRx2 Compared to Placebo for the Treatment of Hypertension (NCT04518306) | George Medicines PTY Limited | 2021-06-14 |
| 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Pneumococcal Vaccine-Naïve Adults 60 Years of Age and Older in Japan, Korea, and Taiwan (NCT04875533) | Pfizer | 2021-06-14 |
| Nebulized Bupivacaine Analgesia for Cleft Palate Repair (NCT04928352) | Assiut University | 2021-06-14 |
| Effects of 100% Medical Grade Manuka Honey on Tympanic Membrane Reconstruction Healing. (NCT05605262) | Fakultas Kedokteran Universitas Indonesia | 2021-06-13 |
| Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅱ (NCT04797013) | Beijing Tiantan Hospital | 2021-06-12 |
| Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs (NCT04928300) | Assiut University | 2021-06-12 |
| Clinical Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19 (NCT04802382) | MGC Pharmaceuticals d.o.o | 2021-06-11 |
| MP0420 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial) (NCT05780463) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-06-11 |
| A Phase III Study of BD0801 Combined With Chemotherapy in Recurrent, Platinum-resistant Epithelial Ovarian Cancer (NCT04908787) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2021-06-11 |
| Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin) (NCT04814511) | Infectopharm Arzneimittel GmbH | 2021-06-11 |
| Intramuscular and Intravenous VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19. (NCT04913675) | Vir Biotechnology, Inc. | 2021-06-10 |
| Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in ICU (NCT05003570) | Southeast University, China | 2021-06-10 |
| Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension (NCT05359068) | Shanghai Pharmaceuticals Holding Co., Ltd | 2021-06-10 |