| Anesthetic Efficacy of %4Alexadricaine Versus %2 Mepicaine-L in Children (NCT04477317) | Cairo University | 2021-08-01 |
| Preoperative Irinotecan Drug-eluting Beads for Patients With Unresectable Colorectal Liver Metastasis (NCT04912258) | Fudan University | 2021-08-01 |
| Seamless Controlled Trial To Evaluate Safety And Immunogenicity of Chikungunya Vaccine in LatinAmerica and Asia (NCT04566484) | International Vaccine Institute | 2021-08-01 |
| Pioglitazone and Insulin Resistance in ADT (NCT05098327) | State University of New York at Buffalo | 2021-08-01 |
| Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour Resection (NCT04762459) | Chinese Academy of Medical Sciences | 2021-08-01 |
| Antiviral Effects of TXA as a Preventative Treatment Following COVID-19 Exposure (NCT04550338) | University of Alabama at Birmingham | 2021-08-01 |
| Recurrence Rate Comparison Between Esomeprazole and Lansoprazole in Eradicating Helicobacter Pylori Infection Among Children (NCT05861687) | Finni Kollins | 2021-08-01 |
| Arrest of Interproximal Caries Lesion With 38% Silver Diamine Fluoride Solution (NCT05791669) | Postgraduate Institute of Dental Sciences Rohtak | 2021-08-01 |
| Spasmodic Dysphonia Pain (NCT04648891) | Mayo Clinic | 2021-08-01 |
| Exercise on Mitochondrial Functions of Lymphocyte in Hemodialysis (NCT06417307) | Chang Gung Memorial Hospital | 2021-08-01 |
| Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer. (NCT05016349) | Mahmoud Ramadan mohamed Elkazzaz | 2021-08-01 |
| Ticagrelor in Post-transplant Patients With Pediatric Hepatic Artery Thrombosis (HAT) (NCT04946929) | RenJi Hospital | 2021-07-31 |
| Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia (NCT04885218) | Jiangsu HengRui Medicine Co., Ltd. | 2021-07-30 |
| JY025 is a First-line Treatment for EGFR Mutated NSCLC Phase II and III Clinical Trials of Efficacy and Safety (NCT04874844) | Beijing Dongfang Biotech Co., Ltd. | 2021-07-30 |
| PROSPECTIVE OPEN LABEL CLINICAL TRIAL TO ADMINISTER A BOOSTER DOSE OF PFIZER/BIONTECH OR MODERNA COVID-19 VACCINE IN HIGH-RISK INDIVIDUALS (NCT05279365) | DHR Health Institute for Research and Development | 2021-07-30 |
| Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder (NCT04985942) | Intra-Cellular Therapies, Inc. | 2021-07-30 |
| REduction of Post-Operative Urinary Retention With Tamsulosin Versus Placebo (REPOURT- P) Trial (NCT04159077) | McMaster University | 2021-07-30 |
| Accelerated Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Pulse or Continuous UV-A Light (NCT05027295) | Cornea and Laser Eye Institute | 2021-07-30 |
| A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat (NCT04981717) | Regeneron Pharmaceuticals | 2021-07-30 |
| Efficacy and Safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Chinese Participants With Inadequately Controlled Asthma (NCT04937387) | GlaxoSmithKline | 2021-07-29 |
| Improvement of Live Babies Rates After ICSI, Using cpFT (NCT04954274) | Assistance Publique - Hôpitaux de Paris | 2021-07-29 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy (NCT04666610) | UCB Biopharma SRL | 2021-07-29 |
| A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions (NCT04914598) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2021-07-28 |
| PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism (NCT05387070) | Visen Pharmaceuticals (Shanghai) Co., Ltd. | 2021-07-28 |
| China Subpopulation: Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma (NCT06868654) | GlaxoSmithKline | 2021-07-28 |
| ECT vs. Esketamine (NCT04924257) | Medical University Innsbruck | 2021-07-28 |
| Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014). (NCT04949256) | Merck Sharp & Dohme LLC | 2021-07-28 |
| Shorter Benznidazole Regimens Compared to the Standard Regimen for Chagas Disease (NCT04897516) | Laboratorio Elea Phoenix S.A. | 2021-07-28 |
| Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy. (NCT04817618) | Novartis Pharmaceuticals | 2021-07-28 |
| Japan Expansion Cohort: Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma (NCT06868667) | GlaxoSmithKline | 2021-07-28 |
| Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances (NCT05361707) | Vanda Pharmaceuticals | 2021-07-28 |
| Serum MicroRNAs 223 and 146a in Allergic Rhinitis Patients as Biomarkers for Efficacy of Sublingual Immunotherapy (NCT04813380) | Zagazig University | 2021-07-27 |
| Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria (NCT04747613) | Novartis Pharmaceuticals | 2021-07-27 |
| Tislelizumab in Combination With Sitravatinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NCT04921358) | BeiGene | 2021-07-27 |
| A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus (NCT04976322) | UCB Biopharma SRL | 2021-07-27 |
| Efficacy and Safety of DKF-313 in Patients With Benign Prostatic Hyperplasia (NCT04947631) | Dongkook Pharmaceutical Co., Ltd. | 2021-07-27 |
| A Clinical Study of Insulin Degludec Injection in Subjects With Type 2 Diabetes (NCT04955834) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-07-27 |
| Ga-68-PSMA-11 in Men With Prostate Cancer (NCT05744115) | Timothy Hoffman | 2021-07-27 |
| Evaluate the Safety and Efficacy of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers (NCT04962139) | Oneness Biotech Co., Ltd. | 2021-07-27 |
| Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias (NCT01013714) | University of California, Los Angeles | 2021-07-26 |
| Phase III Clinical Trial Evaluating the Efficacy and Safety of Ciprofol Injection for the Induction of Sedation/Anesthesia in Subjects Undergoing Gynecological Outpatient Surgeries (NCT04958746) | Haisco Pharmaceutical Group Co., Ltd. | 2021-07-26 |
| Effect of Cyproheptadine on Ventilatory Support-free Days in Critically Ill Patients With COVID-19 (NCT04979221) | Hospital de Clinicas de Porto Alegre | 2021-07-26 |
| Evaluation of ADG20 for the Treatment of Mild or Moderate COVID-19 (NCT04805671) | Invivyd, Inc. | 2021-07-26 |
| Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977 (NCT04862286) | AbbVie | 2021-07-24 |
| Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS (NCT04788615) | Novartis Pharmaceuticals | 2021-07-23 |
| Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy (NCT04741074) | Geisinger Clinic | 2021-07-23 |
| Camrelizumab Combined With Famitinib Malate for Treatment of Recurrent/Metastatic Cervical Cancer (NCT04906993) | Jiangsu HengRui Medicine Co., Ltd. | 2021-07-23 |
| Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies (NCT04933721) | BioCryst Pharmaceuticals | 2021-07-23 |
| A Phase # Clinical Study Trial of Felbinac Trometamol Injection in China (NCT05297669) | Shijiazhuang Yiling Pharmaceutical Co. Ltd | 2021-07-23 |
| Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments (NCT04893525) | University of British Columbia | 2021-07-23 |
| Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected (NCT04729387) | Novartis Pharmaceuticals | 2021-07-22 |
| Study to Compare Efficacy and Safety of CT-P42 in Comparison With Eylea in Patients With Diabetic Macular Edema (NCT04739306) | Celltrion | 2021-07-22 |
| Opioid-Free Anesthesia in Cardiac Surgery (NCT04940689) | University Hospital, Rouen | 2021-07-22 |
| Study of Obeticholic Acid（OCA） Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC) (NCT04956328) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-07-22 |
| A Phase III Clinical Study of a SARS-CoV-2 Messenger Ribonucleic Acid (mRNA) Vaccine Candidate Against COVID-19 in Population Aged 18 Years and Above (NCT04847102) | Walvax Biotechnology Co., Ltd. | 2021-07-22 |
| Citicoline in Ischemic Stroke (NCT05154903) | Ain Shams University | 2021-07-22 |
| A Research Study in Chinese Children With a Low Level of Hormone to Grow. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day. (NCT04970654) | Novo Nordisk A/S | 2021-07-22 |
| Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma (NCT04997837) | Fudan University | 2021-07-21 |
| Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis (NCT04732117) | Novartis Pharmaceuticals | 2021-07-21 |
| Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS) (NCT04993729) | Tasly Pharmaceuticals, Inc. | 2021-07-21 |
| A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications (NCT04877288) | Bristol-Myers Squibb | 2021-07-21 |
| Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis (NCT04740294) | University of Louisville | 2021-07-21 |
| Efficacy and Safety of Benralizumab in Patients With Non-cystic Fibrosis Bronchiectasis (NCT05006573) | AstraZeneca | 2021-07-21 |
| A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older (NCT04908683) | Janssen Vaccines & Prevention B.V. | 2021-07-21 |
| JUVÉDERM® VOLUMA® With Lidocaine for Correction of Temple Hollowing in Chinese Population (NCT04891419) | Allergan | 2021-07-20 |
| Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults. (NCT04076748) | University Hospital, Bordeaux | 2021-07-20 |
| Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION) (NCT04928807) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2021-07-20 |
| Phase 3 Study to Evaluate Intravenous Trappsol(R) Cyclo(TM) in Pediatric and Adult Patients With Niemann-Pick Disease Type C1 (NCT04860960) | Cyclo Therapeutics, Inc. | 2021-07-20 |
| Urine Alkalinisation to Prevent AKI in COVID-19 (NCT04655716) | Guy's and St Thomas' NHS Foundation Trust | 2021-07-19 |
| Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy (NCT04820530) | Novartis Pharmaceuticals | 2021-07-19 |
| Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy (NCT05764525) | Vivozon Pharmaceutical Inc. | 2021-07-19 |
| Treatment of Triple-negative Breast Cancer With Albumin-bound Paclitaxel as Neoadjuvant Therapy: a Prospective RCT (NCT04137653) | Shengjing Hospital | 2021-07-19 |
| Quit2Heal Smartphone App in Helping Cancer Patients Quit Smoking (NCT04409236) | Fred Hutchinson Cancer Center | 2021-07-19 |
| A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children With Atopic Dermatitis (TRuE-AD3) (NCT04921969) | Incyte Corporation | 2021-07-19 |
| The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial (NCT04284839) | Population Health Research Institute | 2021-07-18 |
| Multicenter Open Label Phase 3 Study of Isatuximab Plus Lenalidomide and Dexamethasone With/Without Bortezomib in the Treatment of Newly Diagnosed Non Frail Transplant Ineligible Multiple Myeloma Elderly Patients (≥ 65; < 80 Years). (NCT04751877) | Poitiers University Hospital | 2021-07-17 |
| A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus (NCT04961567) | Biogen | 2021-07-16 |
| Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy (NCT05120076) | Balgrist University Hospital | 2021-07-16 |
| EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19 (NCT04960202) | Pfizer | 2021-07-16 |
| A Multi-center, Double-blinding, Parallel and Positive-controlled Phase III Clinical Trial for Efficacy and Safety Evaluation of Ilaprazole Sodium for Injection on Prevention of Stress Ulcer Bleeding (NCT05841394) | Livzon Pharmaceutical Group Inc. | 2021-07-16 |
| A Trial Comparing a Cellulose Dressing to Two Standard of Care Dressings in Treating Split Thickness Donor Sites in Burn and Wound Patients. (NCT05499104) | Joseph M. Still Research Foundation, Inc. | 2021-07-16 |
| Efficacy of Primary Debulking Surgery Versus Neoadjuvant Chemotherapy in Stage IV Ovarian Cancer (NCT05371301) | Fudan University | 2021-07-16 |
| Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries (NCT05283434) | Children's Hospitals and Clinics of Minnesota | 2021-07-15 |
| A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment (NCT04908189) | Bristol-Myers Squibb | 2021-07-15 |
| A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis (NCT04951622) | Janssen Research & Development, LLC | 2021-07-15 |
| A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-PD-L1 Antibody) in Patients With ES-SCLC (NCT04878016) | Lee's Pharmaceutical Limited | 2021-07-15 |
| Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 (NCT04928495) | Universidade Federal do Ceara | 2021-07-15 |
| Novel Experimental COVID-19 Therapies Affecting Host Response (NCT04924660) | Sean Collins | 2021-07-15 |
| A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus) (NCT04598477) | argenx | 2021-07-15 |
| Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis (NCT04870203) | University Hospital, Bordeaux | 2021-07-15 |
| 3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee Osteoarthritis (NCT04931667) | Biosplice Therapeutics, Inc. | 2021-07-15 |
| Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients (NCT04965935) | University Health Network, Toronto | 2021-07-15 |
| Metformin Plus Tyrosine Kinase Inhibitors for Treatment of Patients With Non-small Cell Lung Cancer With EGFR Mutations (NCT05445791) | Instituto Nacional de Cancerologia de Mexico | 2021-07-15 |
| Lung Perfusion PET / CT Using Ga68-MAA for Preservation of Lung Function During Stereotactic Pulmonary Radiation Therapy (NCT04942275) | University Hospital, Brest | 2021-07-15 |
| A Phase III Study to Assess the Efficacy and Safety of Almonertinib Versus Platinum-based Chemotherapy as First-line Therapy in Patients With Locally Advanced or Metastatic NSCLC Harbouring Uncommon EGFR Mutation (NCT04951648) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2021-07-15 |
| Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma (NCT04979442) | Rain Oncology Inc | 2021-07-14 |
| A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome) (NCT04657289) | Hoffmann-La Roche | 2021-07-14 |
| A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER) (NCT04636801) | Chiesi Farmaceutici S.p.A. | 2021-07-14 |
| Safety Profile of Applied 100% Manuka Honey in Tympanoplasty (NCT05657717) | Fakultas Kedokteran Universitas Indonesia | 2021-07-13 |
| Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome. (NCT05018286) | VectivBio AG | 2021-07-13 |