| Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS (NCT06126315) | Mario Negri Institute for Pharmacological Research | 2025-03-26 |
| Melflufen for Elderly Patients With Relapsed Myeloma (NCT06682637) | Fondazione EMN Italy Onlus | 2025-03-26 |
| A Clinical Study of ONO-1110 in Patients With Fibromyalgia (NCT06752590) | Ono Pharmaceutical Co., Ltd. | 2025-03-26 |
| A Study of NE3107 in Early Parkinson's (NCT06757010) | BioVie Inc. | 2025-03-26 |
| Bacteriophage Therapy for Morganella Morganii Prosthetic Joint Infection (NCT06814756) | University of Calgary | 2025-03-26 |
| A Clinical Study of Boserolimab (MK-5890) With Pembrolizumab and Chemotherapy in People With Early Triple-Negative Breast Cancer (MK-5890-003) (NCT06829199) | Merck Sharp & Dohme LLC | 2025-03-26 |
| To Study Lower Dose of Cyclophosphamide After Stem Cell Transplant for Blood Cancers (NCT07719946) | Tata Memorial Centre | 2025-03-26 |
| Evaluation of Long-Acting Lenacapavir for the Treatment of HIV-1 in Treatment-experienced Adolescents and Children (NCT06749054) | Gilead Sciences | 2025-03-26 |
| Qinqiao Yan Shu Granules for the Treatment of Acute Pharyngitis (Exterior Wind-Heat Syndrome) Phase II Clinical Trial (NCT06932328) | Jianmin Pharmaceutical Group Co., LTD. | 2025-03-26 |
| Phase II Trial of Iparomlimab/Tuvonralimab (QL1706) + XELOX in HER2-Negative, Low PD-L1 G/GEJ Adenocarcinoma (NCT06932068) | Qilu Hospital of Shandong University | 2025-03-26 |
| Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain (NCT06635889) | University of Chicago | 2025-03-26 |
| Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer (NCT06028737) | Ukrainian Society of Clinical Oncology | 2025-03-25 |
| Trial of Atezolizumab, Bevacizumab, and Tiragolumab in Patients With Microsatellite Stable, Metastatic Colorectal Cancer (NCT06784947) | University of Colorado, Denver | 2025-03-25 |
| A Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (NCT06907290) | Mirum Pharmaceuticals, Inc. | 2025-03-25 |
| Study of CM313(SC) Injection in Subjects With Platelet Transfusion Refractoriness (NCT06792019) | Keymed Biosciences Co.Ltd | 2025-03-25 |
| A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002) (NCT06818643) | Merck Sharp & Dohme LLC | 2025-03-25 |
| Extension Study of Participants From SPG302-ALZ-101 (NCT06833281) | Spinogenix | 2025-03-25 |
| Liposomal Irinotecan, 5-fluorouracil/Calcium Folinate, Oxaliplatin, and Adebrelimab in Combination With Radiotherapy for Resectable or Borderline Resectable Pancreatic Cancer With Risk Factors：A Prospective Exploratory Study (NCT07542002) | Ningbo Medical Center Lihuili Hospital | 2025-03-25 |
| HRS-4642 With Nimotuzumab and Chemotherapy for First-line Treatment of Advanced Pancreatic Cancer Patients (NCT06770452) | Zhejiang University | 2025-03-25 |
| Anticholinergics for Cervical Edema in Labor (NCT06702670) | The University of Texas Health Science Center, Houston | 2025-03-25 |
| Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL) (NCT06636786) | University of North Carolina, Chapel Hill | 2025-03-25 |
| Assessing Gingivitis of 3 Different Dentifrices Compared to a Negative Control. (NCT06892834) | Procter and Gamble | 2025-03-25 |
| The Use of 5-ALA in Paediatric Patients With High Grade Brain Tumours (NCT06678867) | University College, London | 2025-03-25 |
| Phase 2 Randomized Double-blind Study to Assess Topical Zabalafin Hydrogel Vs Vehicle in Mild to Moderate AD. (NCT06855745) | Alphyn Biologics | 2025-03-25 |
| Vitamin A Supplementation in Allogeneic Stem Cell Transplantation. (NCT06450925) | Children's Hospital Medical Center, Cincinnati | 2025-03-25 |
| A Trial of a Next Generation COVID-19 Vaccine Delivered by Inhaled Aerosol (NCT06381739) | McMaster University | 2025-03-25 |
| Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma (NCT06731803) | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | 2025-03-25 |
| Luspatercept for Clonal Cytopenias of Uncertain Significance (NCT06788691) | Weill Medical College of Cornell University | 2025-03-25 |
| Memantine as an Additive Therapy in Patients With Traumatic Brain Injury (NCT06914310) | Mansoura University | 2025-03-25 |
| Evaluation of the Preliminary Efficacy and Safety of DR30206 in Combination With Standard Therapy in Patients With Gastrointestinal Cancer (NCT07056777) | Zhejiang Doer Biologics Co., Ltd. | 2025-03-25 |
| Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss (NCT06810544) | Tango Therapeutics, Inc. | 2025-03-24 |
| Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients (NCT06948357) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2025-03-24 |
| A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ALD-102 Solution in Subjects With Alopecia Areata (NCT06826196) | Aldena Therapeutics | 2025-03-24 |
| Evaluating the Efficacy and Safety of of HSK44459 in Patients With Behçet's Disease (NCT06902428) | Haisco Pharmaceutical Group Co., Ltd. | 2025-03-24 |
| Abemaciclib in Newly Diagnosed Meningioma Patients (NCT05940493) | Nader Sanai | 2025-03-24 |
| A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors (NCT06827613) | Marengo Therapeutics, Inc. | 2025-03-24 |
| REGEND001 Autologous Basal Layer Stem Cell Transplantation for Chronic Obstructive Pulmonary Disease (COPD): A Translational Application Study (NCT06946953) | Ruijin Hospital | 2025-03-23 |
| A Phase 2a Study of LLX-424 in Patients With a History of Kidney Stones (NCT06932146) | Lilac Therapeutics, Inc. | 2025-03-23 |
| PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors (NCT06721689) | Theodore Laetsch | 2025-03-23 |
| UBT251 Injection Phase II (Type 2 Diabetes Mellitus) Study (NCT07163624) | The United Bio-Technology (Hengqin) Co., Ltd. | 2025-03-22 |
| Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature (NCT06894225) | National Neuroscience Institute | 2025-03-22 |
| A Phase 1b/2 Clinical Trial Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AUR103 Calcium in Patients With HER2-positive Advanced Gastric/Gastroesophageal Junction Adenocarcinoma (NCT07040059) | Aurigene Discovery Technologies Limited | 2025-03-22 |
| Emapalumab Treatment For Anticipated Clinical Benefit In Sepsis Driven By The Interferon-Gamma Endotype (The EMBRACE Trial) (NCT06694701) | Hellenic Institute for the Study of Sepsis | 2025-03-22 |
| Aleeto in Acute ISchemic Stroke：A RandomISed Controlled Clinical Trial (NCT06759753) | Beijing Tiantan Hospital | 2025-03-21 |
| QL1706 Combined With SOX Used in Theperioperative Treatment (NCT06766305) | Xiangdong Cheng | 2025-03-21 |
| Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV) (NCT06887062) | University of Edinburgh | 2025-03-21 |
| A Study of ATTR-01 in Participants With Select Epithelial Solid Tumours (NCT06977737) | Accession Therapeutics Limited | 2025-03-21 |
| A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors (NCT06914128) | Bayer | 2025-03-21 |
| Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer (NCT06245356) | UNICANCER | 2025-03-21 |
| Methadone to Treat Painful Chemotherapy Induced Peripheral Neuropathy (NCT05786599) | University of British Columbia | 2025-03-21 |
| Efficacy and Safety of the ACC017-Based Antiretroviral Regimen in Treatment-Experienced Adults With HIV-1 Harboring Non-Nucleoside Reverse Transcriptase Inhibitor Resistance Mutations (NCT07711210) | Jiangsu Aidea Pharmaceutical Group Co., Ltd. | 2025-03-21 |
| Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT (NCT06839456) | Children's Hospital of Philadelphia | 2025-03-21 |
| Efficacy of Venetoclax in Combination With Rituximab in Waldenström's Macroglobulinemia (NCT05099471) | Christian Buske | 2025-03-21 |
| A Phase II Study of Dexamethasone, Azacitidine, Pegaspargase and Tislelizumab Plus Radiotherapy for Patients With Stage I/II Extranodal NK/T-cell Lymphoma (NCT07000617) | Peking University Cancer Hospital & Institute | 2025-03-21 |
| Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy (NCT06174220) | Hamilton Health Sciences Corporation | 2025-03-21 |
| Tarlatamab in Advanced Delta-like 3 (DLL3)-Expressing Tumors Including Neuroendocrine Neoplasms (NCT06788938) | Jonsson Comprehensive Cancer Center | 2025-03-21 |
| Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03) (NCT06797635) | Merck Sharp & Dohme LLC | 2025-03-20 |
| A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC) (NCT06708949) | M.D. Anderson Cancer Center | 2025-03-20 |
| SBRT-LDRT-Cadonilimab for Advanced Gastric, Colorectal and Ovarian Cancers With Peritoneal Metastases (NCT06940921) | Zhang Tao | 2025-03-20 |
| A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease (NCT06773962) | TrueBinding, Inc. | 2025-03-20 |
| Tamoxifen for Advanced Solid Pseudopapillary Tumor of the Pancreas (NCT06914674) | Fudan University | 2025-03-20 |
| Electroacupuncture for Preventing Adverse Events of Cancer Immunotherapy (NCT06891521) | Qinghai Red Cross Hospital | 2025-03-20 |
| Paclitaxel Polymersomes + Carboplatin + Adebelimab: Neoadjuvant Phase Ⅱ Single-Arm Study for Resectable Mucosal Melanoma (NCT07336979) | Sun Yat-sen University | 2025-03-20 |
| Exogenous KETOne Supplements in Patients Hospitalized for Acute Heart Failure (NCT06653725) | Aarhus University Hospital | 2025-03-20 |
| Chronic Lung Allograft Dysfunction MRI Study (NCT06406777) | Sean Fain | 2025-03-20 |
| Phase 2b Study of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria (CSU) (NCT06873516) | Evommune, Inc. | 2025-03-20 |
| Walking With Overground Robotic Exoskeletons to Improve Arrousal in Individuals With Disorders of Consciousness (NCT06780280) | Craig Hospital | 2025-03-20 |
| Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors (NCT05626894) | Spaulding Rehabilitation Hospital | 2025-03-20 |
| Clinical Trial of SYS6010±SYH2051 Versus Chemotherapy in Advanced Breast Cancer and Other Solid Tumors (NCT06775236) | CSPC Megalith Biopharmaceutical Co.,Ltd. | 2025-03-20 |
| Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01) (NCT06788912) | Merck Sharp & Dohme LLC | 2025-03-20 |
| Precision Cancer Therapy in Rare Cancers (NCT06119789) | Oslo University Hospital | 2025-03-20 |
| Phase II/III Seamless Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Treatment of Seasonal Allergic Rhinitis (NCT06846385) | Shanghai Mabgeek Biotech.Co.Ltd | 2025-03-20 |
| Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk (NCT06649929) | University of Utah | 2025-03-20 |
| Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis (NCT07547735) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-03-20 |
| Neoadjuvant/Adjuvant Sintilimab, Nab-paclitaxel, and Gemcitabine for Resectable/Borderline Resectable Pancreatic Cancer (NCT05562297) | Shanghai Zhongshan Hospital | 2025-03-20 |
| Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia (NCT06604520) | Johns Hopkins University | 2025-03-20 |
| A Phase 2 Study to Evaluate Efficacy and Safety of KH607 Tablets in Adult Participents With Major Depressive Disorder (NCT07101120) | Chengdu Kanghong Pharmaceutical Group Co., Ltd. | 2025-03-19 |
| A Study of LY3541860 in Adult Participants With Moderately to Severely Active Rheumatoid Arthritis (NCT06859294) | Eli Lilly and Company | 2025-03-19 |
| Roginolisib (IOA-244) With Venetoclax and Rituximab for Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL) (NCT06644183) | Jennifer R. Brown, MD, PhD | 2025-03-19 |
| Clinical Study on Neoadjuvant Therapy of Homoharringtonine Combined With Androgen Deprivation for Prostate Cancer (NCT06834321) | baotai Liang | 2025-03-19 |
| Interleukin-2 for Refractory Chronic Spontaneous Urticaria (NCT06924762) | Second Xiangya Hospital of Central South University | 2025-03-19 |
| Assessment of Safety, Immunogenicity and Efficacy of R21/Matrix-M1 Malaria Vaccine in Healthy WOCBP in Mali (NCT06080243) | University of Oxford | 2025-03-19 |
| Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", With a Single Intraperitoneal Use After Surgery in Adult Patients With Acute Phlegmonous Appendicitis (NCT06365632) | Research Institute for Physical Chemical Problems of the Belarusian State University | 2025-03-19 |
| Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym (NCT06760156) | H. Lee Moffitt Cancer Center and Research Institute | 2025-03-19 |
| Efficacy, Safety, and Tolerability of HB0043 in Hidradenitis Suppurativa Patients. (NCT06895499) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2025-03-19 |
| [18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease (NCT07104487) | Universitaire Ziekenhuizen KU Leuven | 2025-03-18 |
| Trial Studying Chemotherapy in Nigerian Women With Triple Negative Breast Cancer (NCT06291064) | University of Chicago | 2025-03-18 |
| Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple Myeloma (NCT06785415) | Mayo Clinic | 2025-03-18 |
| Intrathecal PD-1/VEGF Bispecific Antibody Plus Pemetrexed for Leptomeningeal Metastasis (NCT06809517) | Guangzhou Medical University | 2025-03-18 |
| BCMA CAR-T for Dynamic High-risk Multiple Myeloma (NCT06880393) | Institute of Hematology & Blood Diseases Hospital, China | 2025-03-18 |
| Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial) (NCT06311214) | National Cancer Institute (NCI) | 2025-03-18 |
| Assessing the Efficacy and Safety of Anti-HER2 Therapy in Nigerian Women With HER2+ Breast Cancer Before and After Surgery (NCT06348134) | University of Chicago | 2025-03-18 |
| A Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer (NCT06840002) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-03-18 |
| Effect of Tirzepatide on Brown Adipose Tissue in Obesity (NCT06893211) | University Medical Centre Ljubljana | 2025-03-18 |
| Pegylated Liposomal Doxorubicin Plus Adebrelimab With or Without Mirabegron in Relapsed Ovarian Cancer (NCT06791460) | Obstetrics & Gynecology Hospital of Fudan University | 2025-03-18 |
| Phase 2 Trial of RGX-314 in Adults With Center Involved - Diabetic Macular Edema (CI - DME) (NCT06942520) | Sierra Eye Associates | 2025-03-18 |
| Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF (NCT06655480) | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | 2025-03-18 |
| Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (NCT07032662) | Immunovant Sciences GmbH | 2025-03-18 |
| HAIC Combined With Sintilimab Plus Bevacizumab Biosimilar for Advanced Hepatocellular Carcinoma (TASK-03) (NCT06860490) | Fudan University | 2025-03-18 |
| A Study to Evaluate the Efficacy and Safety of LNK01004 Ointment in Adults With Atopic Dermatitis (NCT07071610) | Lynk Pharmaceuticals Co., Ltd | 2025-03-18 |