| A Phase 2b Study to Evaluate the Efficacy and Safety of Once-Monthly MET097 in Adults With Obesity or Overweight (NCT06973720) | Pfizer | 2025-04-07 |
| LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced Melanoma (NCT06623461) | Canadian Cancer Trials Group | 2025-04-07 |
| Efficacy and Safety of HRS9531 Tablet in Obese Subjects (NCT06841445) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2025-04-07 |
| Study to Expand Safety and Immunogenicity Data With Shigella Bioconjugate Vaccine (Shigella4V2) in 9-month-old Infants. (NCT06523231) | LimmaTech Biologics AG | 2025-04-07 |
| Postoperative Pain Comparison of Two Root Canal Sealers in Irreversible Pulpitis (NCT06975761) | Armed Forces Institute of Dentistry, Pakistan | 2025-04-07 |
| Dragon Boat Race Versus Family Unsupervised Training to Improve the Physical Function and Quality of Life in Breast Cancer Patients (NCT07162298) | First Affiliated Hospital of Zhejiang University | 2025-04-07 |
| EXploratory Study on Postprandial Energy Metabolism (NCT06786052) | Lallemand Health Solutions | 2025-04-07 |
| Role of Kefir Mouth Wash in Oral Health Status Amelioration (NCT06900881) | Al-Mustansiriyah University | 2025-04-06 |
| Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age (NCT05766839) | Vifor Pharma, Inc. | 2025-04-06 |
| Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain Injury (NCT05616910) | University of Pennsylvania | 2025-04-06 |
| Short-Course Anti-tuberculosis Regimens for Mild Spinal Tuberculosis (NCT06917495) | Shandong University | 2025-04-05 |
| Neoadjuvant Chemo-immunotherapy Followed by Concurrent Chemoradiotherapy and Immunotherapy in LACC (NCT06916117) | RenJi Hospital | 2025-04-05 |
| Hypofractionated vs. Conventional Chemoradiotherapy After Induction Chemo-immunotherapy for Unresectable Esophageal Squamous Cell Carcinoma (NCT06912074) | Sun Yat-sen University | 2025-04-05 |
| Combining Dexmedetomidine Infusion and Paragastric Autonomic Neural Block to Enhance Postoperative Recovery in Patients Undergoing Laparoscopic Sleeve Gastrectomy (NCT06970678) | Alexandria University | 2025-04-04 |
| A Phase Ib/II Trial of Neoadjuvant Zolbetuximab Plus Docetaxel, Oxaliplatin and S-1 Chemotherapy in Patients With Locally Advanced Gastric Cancer (NCT06732856) | Asan Medical Center | 2025-04-04 |
| GATEWAY: A Phase 2a Study of PORT-77 in Adults With Erythropoietic Protoporphyria (NCT06971900) | Portal Therapeutics, Inc. | 2025-04-04 |
| A Study to Evaluate the Safety of Recombinant Herpes Zoster Vaccine for Healthy Individuals (NCT06932523) | Shanghai Institute Of Biological Products | 2025-04-04 |
| A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD) (NCT06450639) | Hoffmann-La Roche | 2025-04-04 |
| A Study of Ivonescimab in People With Endometrial and Cervical Cancers (NCT06925724) | Memorial Sloan Kettering Cancer Center | 2025-04-04 |
| Cannabidiol in Sickle Cell Disease (NCT06930703) | Icahn School of Medicine at Mount Sinai | 2025-04-03 |
| Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDD (NCT06828887) | Vigonvita Life Sciences | 2025-04-03 |
| Evaluation of Clinical, Perceived and Instrumental Efficacy of a Scar Gel in Preventing Hypertrophic Scars (NCT06751433) | Herbarium Laboratorio Botanico Ltda | 2025-04-03 |
| Quality of Recovery in Laparoscopic Sleeve Gastrectomy Using Dexmedetomidine Infusion Versus Laparoscopic TAP Block in Combination With Paragastric Neural Block (NCT06970626) | Alexandria University | 2025-04-03 |
| A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI Participants (NCT06889701) | TenNor Therapeutics Inc. | 2025-04-03 |
| A Study of BGM0504 in Participants With Obesity (NCT06911203) | BrightGene Bio-Medical Technology Co., Ltd. | 2025-04-03 |
| Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain (NCT05519111) | Icahn School of Medicine at Mount Sinai | 2025-04-03 |
| The Safety and Effectiveness of Hyperthermic Intraperitoneal Chemotherapy Combined With Intravenous Chemotherapy for Peritoneal Metastatic Pancreatic Cancer, a Phase II Clinical Trial (NCT06946901) | Shanghai Zhongshan Hospital | 2025-04-03 |
| Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors (NCT06726148) | Novartis Pharmaceuticals | 2025-04-03 |
| Post-operative Intravenous Iron to Treat Iron-deficiency Anemia in Patients Undergoing Cardiac Surgery (NCT06287619) | University Health Network, Toronto | 2025-04-03 |
| A Phase II Study of Toripalimab Combined With Sequential Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma (NCT06843889) | Nanfang Hospital, Southern Medical University | 2025-04-03 |
| Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer (NCT06830239) | Universitaire Ziekenhuizen KU Leuven | 2025-04-03 |
| Clinical Trial With MBK-01, Intestinal Microbiota Capsules, for the Treatment of Patients With Recurrent Diverticulitis (NCT06687382) | Mikrobiomik Healthcare Company S.L. | 2025-04-03 |
| A Trial of HRS-8427 in the Treatment of Adults With Bacterial Pneumonia (NCT06841731) | Jiangsu HengRui Medicine Co., Ltd. | 2025-04-03 |
| Probiotic Supplementation and Disease Progression in CKD: A Randomized Trial (NCT06863194) | Mansoura University | 2025-04-03 |
| A Clinical Trial of Furmonertinib Combined With Anlotinib as First-line Treatment for Advanced NSCLC With EGFR-sensitive Mutations and Brain Metastasis (NCT06945705) | Henan Cancer Hospital | 2025-04-02 |
| SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal Cancer (NCT06908031) | Sixth Affiliated Hospital, Sun Yat-sen University | 2025-04-02 |
| A Phase II Study to Evaluate HLX43 in Subjects With Recurrent/Metastatic Nasopharyngeal Carcinoma Failed or Intolerance to Second-line Therapy (NCT06839066) | Shanghai Henlius Biotech | 2025-04-02 |
| G-CSF After Chemo-radiation in Patients With Glioblastoma (NCT06649851) | Massachusetts General Hospital | 2025-04-02 |
| Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea (NCT06776432) | Shionogi | 2025-04-02 |
| A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial Cystitis (NCT06752603) | Ono Pharmaceutical Co., Ltd. | 2025-04-02 |
| Flexion-Distraction Technique (NCT06886334) | Istanbul Medipol University Hospital | 2025-04-02 |
| Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy (NCT06834373) | Mayo Clinic | 2025-04-02 |
| Intensification Treatment of Ovarian Cancer by PIPAC (NCT07514494) | Moscow Regional Oncological Dispensary | 2025-04-02 |
| Evaluation of Postoperative Pain in Cases Undergoing Cataract Surgery Under Topical Versus General Anesthesia (NCT07287683) | Alexandria University | 2025-04-02 |
| Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma (NCT06536049) | Yazeed Sawalha | 2025-04-02 |
| Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection (NCT06849544) | Clinton Bahler | 2025-04-02 |
| A Clinical Study of 9MW2821 Monotherapy or Combined With Other Anticancer Therapy in Advanced Solid Tumors (NCT06947226) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2025-04-01 |
| Lenvatinib, Sintilimab, and DEB-TACE With/Without HAIC for HCC >7 cm With PVTT (NCT06904183) | Second Affiliated Hospital of Guangzhou Medical University | 2025-04-01 |
| Efficacy and Safety of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL (NCT06803693) | Ruijin Hospital | 2025-04-01 |
| Evaluation of Efficacy and Safety of Intradiscal Gelified Ethanol in Refractory Cervical Discogenic Pain (NCT05969392) | Gelscom SAS | 2025-04-01 |
| Phase 2/3 Study of TLC590 for Postsurgical Pain Management (NCT05161637) | Taiwan Liposome Company | 2025-04-01 |
| Preoperative 5-Day Radiotherapy for Soft Tissue Sarcoma (NCT06905132) | Medical University of South Carolina | 2025-04-01 |
| A Randomized Controlled Trial of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy Decision-Making in High-Risk Stage III (T4N+ or T1-3N2) Colorectal Cancer (NCT07562490) | Fudan University | 2025-04-01 |
| Hypofractionation Radiotherapy in Combination With Glofitamab in Relapsed/Refractory Diffuse B-cell Lymphoma With Baseline High Tumor Burden (NCT06867536) | Liling Zhang | 2025-04-01 |
| OBSiDiAN in a Stapled Circular Esophagogastric Anastomosis After Ivor Lewis Esophagectomy (NCT05713955) | University Hospital, Ghent | 2025-04-01 |
| Hypofractionated Radiotherapy Followed by Chemo-immunotherapy Induction Therapy (NCT06914050) | Tianjin Medical University Cancer Institute and Hospital | 2025-04-01 |
| BCAAs in Concussion 2.0 (NCT06829498) | Akiva Cohen | 2025-04-01 |
| Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye (NCT06921525) | Ehab Mohamed Elsayed Mohamed Saad | 2025-04-01 |
| Tailoring Obesity Treatment Trial (NCT06619015) | Esbjerg Hospital - University Hospital of Southern Denmark | 2025-04-01 |
| Study to Evaluate the Safety and Efficacy of ARI0002h, for the Initial Treatment of Patients With Primary Plasma Cell Leukaemia (NCT06830733) | Fundacion Clinic per a la Recerca Biomédica | 2025-04-01 |
| Personalized Tumor Neoantigen MRNA Therapy Adjuvant Treatment for Postoperative Pancreatic Cancer. (NCT06888674) | Zhejiang University | 2025-04-01 |
| A Study of the Safety and Efficacy of Pancreatic Endocrine Cell Clusters Implanted Into the Omentum of Type 1 Diabetes Patients With Severe Hypoglycemia (NCT06651515) | Seraxis | 2025-04-01 |
| The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans (NCT06778434) | VA Office of Research and Development | 2025-04-01 |
| ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty (NCT06753916) | Massachusetts Eye and Ear Infirmary | 2025-04-01 |
| Icaritin in Combination With AG in Patients With Previously Untreated Advanced Pancreatic Ductal Adenocarcinoma (NCT06825546) | Sir Run Run Shaw Hospital | 2025-04-01 |
| Effect of Intracoronary N-Acetylcysteine in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (NCT06850831) | dr. Ahmad Yasa, Sp.JP, Subsp.K.I.(K), M.Kes, FIHA, FasCC, FA | 2025-04-01 |
| MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas (NCT06712875) | Ann & Robert H Lurie Children's Hospital of Chicago | 2025-04-01 |
| Effect of Finerenone in Patients With Non-diabetic Glomerulonephritis (NCT06835322) | Alexandria University | 2025-04-01 |
| NK Cell Infusion for Remission Consolidation in AML: A Phase II Trial (NCT06783478) | Hospital de Clinicas de Porto Alegre | 2025-04-01 |
| This is a Two-cohort, Exploratory Clinical Study Assessing the Activity of Benmelstobart Alone or Combined with Anlotinib Administered Prior to Surgery in Terms of Pathological Complete Response (NCT06851169) | Tang-Du Hospital | 2025-04-01 |
| CD7 CAR T-Cell Therapy for r/r T-cell Lymphomas (NCT06925464) | Beijing GoBroad Hospital | 2025-04-01 |
| JMT101 Combined With Mitoxantrone Liposome for Nasopharyngeal Cancer (NCT06892431) | Shanghai JMT-Bio Inc. | 2025-04-01 |
| Cerebrospinal Fluid Cytology-guided Intrathecal Chemo-holiday Therapy for EGFR-positive NSCLC Leptomeningeal Metastases (NCT06861218) | Zhejiang Cancer Hospital | 2025-04-01 |
| Exploratory Clinical Study on the Safety and Efficacy of CAR-T Cell Therapy in the Treatment of Relapsed/Refractory Myeloid Malignancies (NCT06917105) | Tongji Hospital | 2025-04-01 |
| Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread (NCT07193654) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-04-01 |
| A Clinical Study on Fasudil Hydrochloride for Treatment of Gene-Specific Ovarian Cancer (NCT06890858) | Zhejiang Provincial People's Hospital | 2025-04-01 |
| A Study of SGB-9768 in Patients with Complement-mediated Kidney Diseases (NCT06786338) | Suzhou Sanegene Bio Inc. | 2025-04-01 |
| Lenvatinib Plus SIRT vs Lenvatinib in TACE-Refractory HCC (NCT06904196) | Second Affiliated Hospital of Guangzhou Medical University | 2025-04-01 |
| The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin (NCT05961501) | Wroclaw Medical University | 2025-04-01 |
| Efficacy of Nutritional Supplements on Children With Autism Spectrum Disorder (NCT06911905) | Fei Li | 2025-04-01 |
| A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis (NCT06863961) | Hoffmann-La Roche | 2025-04-01 |
| Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution Working (NCT06980493) | Sohag University | 2025-04-01 |
| Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC (NCT06553885) | H. Lee Moffitt Cancer Center and Research Institute | 2025-04-01 |
| Toripalimab Adjuvant Therapy in Subjects With Resected Esophageal Squamous Cell Carcinoma Who Achieved Pathological Complete Response (pCR) (NCT06903871) | Hebei Medical University Fourth Hospital | 2025-04-01 |
| BMX-001 + Paclitaxel in Adult Patients With Advanced, Recurrent, Metastatic Ovarian or Endometrial Cancer (NCT06620029) | BioMimetix JV, LLC | 2025-04-01 |
| Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal Cancer (NCT06872606) | Sir Run Run Shaw Hospital | 2025-04-01 |
| Glumetinib Combined With Osimertinib Treatment for Non-Small Cell Lung Cancer Patients (NCT06908772) | Shanghai JMT-Bio Inc. | 2025-04-01 |
| Adaptive Versus Non-adaptive Radiotherapy and 2 Bladder Filling Instructions for Patients with Intermediate or High Risk Localized Prostate Cancer (ARP) (NCT06678126) | Scott Tyldesley | 2025-04-01 |
| A Trial of Camrelizumab Plus Nab-paclitaxel and Levocetirizine in Metastatic or Recurrent TNBC (NCT06632405) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2025-04-01 |
| Electroacupuncture Combined With Paclitaxel Protein-bound and PD-1 Antibody for Second-line Treatment of HER2 Negative, pMMR/MSS Advanced Gastric Cancer (NCT06992024) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-04-01 |
| Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions (NCT07113847) | British University In Egypt | 2025-04-01 |
| Antarctic Krill Oil for Knee Osteoarthritis Pain (NCT06880926) | Qilu Hospital of Shandong University | 2025-04-01 |
| Effect of Alpha-1 Antitrypsin Supplementation on Alcohol-Associated Hepatitis (NCT06582329) | Medical University Innsbruck | 2025-04-01 |
| Icaritin Soft Capsules+TACE+Immunotherapy+Targeted Therapy Versus TACE+Immunotherapy+Targeted Therapy for Unresectable Hepatocellular Carcinoma (NCT06896396) | Zhiyong Huang | 2025-04-01 |
| Tacrolimus Lipid Suspension for Enema in Adult Subjects with Mild to Moderately Active Left-sided/Distal Ulcerative Colitis Who Had an Inadequate Response to the Treatment (NCT06867042) | Jina Pharmaceuticals Inc. | 2025-04-01 |
| Effectiveness of a Wearable Hydration Device (NCT06788795) | MetroHealth Medical Center | 2025-04-01 |
| Postoperative Pain and Incidence of Extrusion Following the Use of Two Intra-canal Medications in Retreatment of Single Rooted Teeth (NCT06913673) | Minia University | 2025-04-01 |
| Radiotherapy in Combination With Checkpoint Inhibition for Patients With Metastatic Kidney Cancer (NCT06601296) | University of Texas Southwestern Medical Center | 2025-04-01 |
| Study of Targeted CD22/CD19 CAR-T Therapy for First-line Consolidation of B-cell Lymphoma (NCT07094477) | Daihong Liu | 2025-04-01 |
| Single-Center Trial on Ketogenic Diet and Immunotherapy in Advanced Cancer This Study Evaluates the Safety and Effects of a Ketogenic Diet (KD) Combined With Immunotherapy in Adults With Advanced Melanoma, cSCC, or RCC. (NCT06896552) | Rabin Medical Center | 2025-04-01 |