| CEB-01 in Paediatrics With Locally Resectable Abdominal Tumours (NCT06986811) | CEBIOTEX | 2025-05-06 |
| A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2) (NCT06952699) | Takeda | 2025-05-06 |
| CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus (NCT06839976) | Children's Hospital of Philadelphia | 2025-05-06 |
| Chemoimmunotherapy With or Without SBRT Before Surgery for Locally Advanced Oral and Oropharyngeal Cancer (NCT06861712) | Sun Yat-sen University | 2025-05-06 |
| A Trial of MHB088C in Advanced Extrapulmonary Neuroendocrine Cancer (NCT06951243) | Beijing GoBroad Hospital | 2025-05-06 |
| Safety of HRX215 in Patients After Minor and Major Liver Resection (NCT06638502) | HepaRegeniX GmbH | 2025-05-06 |
| Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT) (NCT07202052) | Monash University | 2025-05-06 |
| A Study of LM-168 as a Single Agent or in Combination With Toripalimab in Subjects With Advanced Solid Tumours (NCT06868199) | LaNova Medicines Limited | 2025-05-06 |
| Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Immunoglobulin Stopping or Extension (Stop Ig) (NCT07202091) | Monash University | 2025-05-06 |
| A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia (NCT06860269) | Assistance Publique - Hôpitaux de Paris | 2025-05-06 |
| STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas (NCT06975293) | STORM Therapeutics LTD | 2025-05-05 |
| Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer (NCT06910761) | City of Hope Medical Center | 2025-05-05 |
| A Study of REGN7544 for the Treatment in Adult Patients With Sepsis-Induced Hypotension (NCT06608901) | Regeneron Pharmaceuticals | 2025-05-05 |
| A Phase 2 Trial Investigating the Safety, Tolerability and Efficacy of EXT608 in Adults With Hypoparathyroidism (NCT06988670) | Extend Biosciences Inc. | 2025-05-05 |
| A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity (NCT06965413) | Hoffmann-La Roche | 2025-05-05 |
| WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF) (NCT06967805) | Mediar Therapeutics | 2025-05-05 |
| Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder (NCT06939088) | Anders Fink-Jensen, MD, DMSci | 2025-05-05 |
| Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis (NCT07065773) | Vanda Pharmaceuticals | 2025-05-05 |
| Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (NCT06406114) | Massachusetts General Hospital | 2025-05-05 |
| Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation (NCT05790213) | University of Chicago | 2025-05-05 |
| Orelabrutinib Combined With Pola-R-CHP Regimen for the Treatment of Untreated Non-GCB Diffuse Large B-Cell Lymphoma (NCT07078500) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-05-05 |
| Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated With Pirtobrutinib After Previous Treatment With Zanubrutinib (NCT06812715) | Peter MacCallum Cancer Centre, Australia | 2025-05-05 |
| Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal Cholangiocarcinoma (NCT06923475) | Amsterdam UMC, location VUmc | 2025-05-05 |
| A Study to Prevent Infantile Spasms Relapse (NCT06819670) | University of California, Los Angeles | 2025-05-05 |
| H01 in Adults With Interstitial Lung Disease (The SOLIS Study) (NCT06325696) | National Institute of Environmental Health Sciences (NIEHS) | 2025-05-05 |
| Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease (NCT06663722) | University of Miami | 2025-05-05 |
| Treatment of Moderate to Severe Refractory Crohn's Disease (NCT06721962) | Tr1X, Inc. | 2025-05-05 |
| Aspirin for Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (NCT06935994) | Taichung Veterans General Hospital | 2025-05-05 |
| A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee (NCT06828666) | Britecyte | 2025-05-05 |
| Neoadjuvant Chemotherapy in Combination With Anlotinib and Benmelstobart for HR+/HER2- Breast Cancer (NEOTORCH-BREAST03) (NCT06874933) | First Affiliated Hospital of Zhejiang University | 2025-05-04 |
| Comparison of ATLG and ATG for Immune Reconstitution After Allo-HSCT for Hematologic Malignancy (NCT06895538) | Peking University First Hospital | 2025-05-03 |
| Finerenone Treatment for Diabetic Cardiovascular Autonomic Neuropathy: the FibroCAN Study (NCT06906081) | Peter Rossing | 2025-05-02 |
| Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL) (NCT06810778) | Jonsson Comprehensive Cancer Center | 2025-05-02 |
| ISTH/ANRS 0409s INTEGRATE Lassa Fever Study (NCT06212336) | Irrua Specialist Teaching Hospital | 2025-05-02 |
| Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma (NCT06798363) | West China Hospital | 2025-05-02 |
| "HB-adMSCs for the Treatment of Patients With Multiple Sclerosis" (NCT06800404) | Hope Biosciences Research Foundation | 2025-05-02 |
| A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer (NCT06892548) | BioNTech SE | 2025-05-02 |
| mRNA Covid-19 Vaccine Immune Response Comparisons Using Different Delivery Routes (NCT06919796) | PharmaJet, Inc. | 2025-05-01 |
| 3D-printed Biodegradable Breast Implants for Breast Restoration (NCT06993714) | Xijing Hospital | 2025-05-01 |
| Establishment of Precision Targeted Therapy Strategies for Advanced Gastric Cancer Based on Novel Molecular Subtyping (NCT06881017) | China Medical University, China | 2025-05-01 |
| Treatment of Nosebleeds in the Emergency Department With Powder Tranexamic Acid (NCT06997796) | Dr. Anne Conlin | 2025-05-01 |
| Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer （SPARK） (NCT07005570) | Dechang Diao | 2025-05-01 |
| Ultrasound Guided Lumbar Erector Spinae Block Using Bupivacaine - Magnesium Sulphate Versus Bupivacaine - Dexamethasone in Total Hip Replacement Surgery (NCT07418671) | Ain Shams University | 2025-05-01 |
| The Relationship Between Microbioma Balance and Acne Vulgaris as a New Acne Treatment (NCT06925386) | Universitas Padjadjaran | 2025-05-01 |
| Safety, Tolerability and Efficacy of Intravitreal KIO-104 in Patients With Macular Edema (NCT06825702) | Kiora Pharmaceuticals, Inc. | 2025-05-01 |
| Determine the Dose-dependent Efficacy and Safety of EC-18 in Patients With Moderate to Severe Atopic Dermatitis (NCT06487000) | Enzychem Lifesciences Corporation | 2025-05-01 |
| A Clinical Trial on Autologous NK Cells Combined With GD2 Monoclonal Antibody in the Treatment of Children With Newly Diagnosed High-risk or Relapsed/Refractory Neuroblastoma (NCT06948994) | Guangzhou Women and Children's Medical Center | 2025-05-01 |
| An Exploratory Clinical Study of HRS-4642 in Combination With Immunotherapy and Chemotherapy for Pancreatic Cancer (NCT06938282) | Shanghai Zhongshan Hospital | 2025-05-01 |
| A Study of Bemosubaiabimab Combined With Anlotinib and Radiotherapy and Chemotherapy for the Treatment of Oligometastatic Esophageal Cancer (NCT07455019) | The First Affiliated Hospital with Nanjing Medical University | 2025-05-01 |
| Autologous Bone Marrow Aspirate (IV) and Bone Marrow Concentrate (Intranasal) for Parkinson's Disease and Parkinson-Plus Syndromes (SPARC-PD) (NCT07751640) | Apeiron Research Center | 2025-05-01 |
| Real-world Experience With Combination Chemotherapy and Osimertinib in Poor Prognostic Group of Metastatic EGFR-mutated Lung Adenocarcinoma (NCT06918782) | The University of Hong Kong | 2025-05-01 |
| Node-Sparing Short-Course Radiotherapy Plus Chemotherapy, Bevacizumab and PD-1 Inhibitor in Metastatic pMMR/MSS Colorectal Cancer (MODIFI-CRC) (NCT06958419) | Sixth Affiliated Hospital, Sun Yat-sen University | 2025-05-01 |
| The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia (NCT06949904) | Mian Muhammad Hassan Ahmed | 2025-05-01 |
| Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy (NCT06483061) | University of Alberta | 2025-05-01 |
| Phase II Study of Atezolizumab and Tiragolumab With ctDNA for HPV-positive SCC (NCT06762808) | M.D. Anderson Cancer Center | 2025-05-01 |
| Intravenous Iron in Combination With Standard of Care Immunotherapy in Melanoma (NCT06508827) | Indiana University | 2025-05-01 |
| An Open-label, Single-arm, Multicenter Phase II Study to Evaluate the Efficacy of Amivantamab in Combination With FOLFIRI as a Second-line Treatment in Patients With RAS/BRAF Wild-type Advanced Colorectal Cancer Progressing on Prior Anti-EGFR Based Treatment. (NCT06855849) | Yonsei University | 2025-05-01 |
| Afatinib Combined With Chemotherapy as Conversion Therapy in Unresectable EGFR Sensitive Mutation-positive Stage III NSCLC (NCT06709859) | Shandong Public Health Clinical Center | 2025-05-01 |
| Impact of Chromium Supplementation on Glucido-lipidic Metabolism, Oxidative Stress and Inflammatory State in Patients with Gestational Diabetes (NCT06860087) | University of Kasdi Merbah | 2025-05-01 |
| Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty Sleeping (NCT06928766) | Flinders University | 2025-05-01 |
| SNIFF - 3-Week Aptar CPS Device (NCT05006599) | Wake Forest University Health Sciences | 2025-05-01 |
| Repeated Neurocognitive Measurements in Depressed Patients (NCT05991232) | Jay Fournier | 2025-05-01 |
| Oncolytic Virus H101 Combined With Lenvatinib Plus Toripalimab Compared With FOLFOX in Patients With Advanced Biliary Tract Cancer (OPTIONS-06) (NCT06919848) | Fudan University | 2025-05-01 |
| Novel Chinese Medicine Formula for Diabetes (NCT06978023) | Chinese University of Hong Kong | 2025-05-01 |
| The Efficacy and Safety of Pucotenlimab Combined With TP Chemotherapy as Neoadjuvant Therapy for Locally Advanced HNSCC (NCT06895369) | Sir Run Run Shaw Hospital | 2025-05-01 |
| Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures (NCT06942182) | TNF Pharmaceuticals, Inc. | 2025-05-01 |
| Window of Opportunity Study of Topical Tranexamic Acid for Cutaneous Squamous Cell Carcinoma (NCT06644079) | University of Florida | 2025-05-01 |
| Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis (NCT06859164) | University of Chicago | 2025-05-01 |
| REAMBERIN® 1.5% in Rehydration Therapy of Diabetic Ketoacidosis (NCT06955416) | POLYSAN Scientific & Technological Pharmaceutical Company | 2025-05-01 |
| A Study of SHR-1826 Monotherapy or in Combination With Immunotherapy in the Treatment of Advanced Hepatocellular Cancer (NCT06935175) | Shanghai Zhongshan Hospital | 2025-05-01 |
| Comparison of Continuous Intravenous Lidocaine Infusion Versus ESP Block for Rib Fracture Analgesia (NCT04707183) | Stanford University | 2025-05-01 |
| Phase I/IIa Dose Finding Study of Triplet Regimen of Relatlimab Ipilimumab and NIvolumab in First Line Therapy of Metastatic Melanoma (TRINITY) (NCT06683755) | M.D. Anderson Cancer Center | 2025-05-01 |
| Anlotinib Combined With Benmelstobart for Advanced Pheochromocytoma (NCT06429397) | Sun Yat-sen University | 2025-05-01 |
| Posaconazole Plus PD-1 Inhibitors and Chemotherapy vs PD-1 Inhibitors and Chemotherapy in Neoadjuvant Therapy for Triple Negative Breast Cancer (NCT06802757) | Shandong Cancer Hospital and Institute | 2025-05-01 |
| Phase 2 Study of Fingolimod in Lung Cancers (NCT06424067) | Medical University of South Carolina | 2025-05-01 |
| QL1706-Based Therapy Post-PD-1/L1 Failure in Advanced Endometrial Cancer (NCT06917092) | Tianjin Medical University Cancer Institute and Hospital | 2025-05-01 |
| iMagIng pulmonaRy Aspergillosis Using Gallium-68-dEferoxamine (NCT06244979) | Radboud University Medical Center | 2025-05-01 |
| Comparing ASCT Followed by Anti-BCMA CAR-T vs. ASCT Alone in NDMM Patients Eligible for ASCT (NCT06963866) | Xuzhou Medical University | 2025-05-01 |
| Molecular Imaging of DNA Damage Response by [18F]-Olaparib PET (NCT06482307) | University Medical Center Groningen | 2025-05-01 |
| A Single-Arm, Open Phase I Clinical Study of Selinexor in Combination With Azacitidine for the Treatment of High-Risk AML/MDS Patients After Allo-HSCT (NCT07779031) | Liping Dou | 2025-05-01 |
| Hyperpolarized 13C-MRI in Patients With Hepatocellular Carcinoma Undergoing Radiotherapy, Atezolizumab, and Bevacizumab (NCT06605664) | Chang Gung Memorial Hospital | 2025-05-01 |
| The Effect of Amantadine as add-on Therapy for Motor Fluctuations in Advanced Parkinson's Disease: a Randomized Double-blinded Placebo-controlled Trial (NCT06817200) | University Hospital, Toulouse | 2025-05-01 |
| Iparomlimab and Tuvonralimab Injection (QL1706) Combined With Bevacizumab for Postoperative Adjuvant Therapy in Hepatocellular Carcinoma (HCC) With High Risk of Recurrence (NCT06958484) | The Affiliated Hospital of Xuzhou Medical University | 2025-05-01 |
| A Phase I/II Multiple Center Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Malignancies (NCT03050190) | Shenzhen Geno-Immune Medical Institute | 2025-05-01 |
| Maintenance or Withdrawal of Urate Lowering Therapy According to Ultrasound Features in Gout Patients: a Randomised Controlled Trial Stop Treatment In Gout (NCT06956885) | Assistance Publique - Hôpitaux de Paris | 2025-05-01 |
| Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection (NCT06942624) | Orthopaedic Innovation Centre | 2025-05-01 |
| A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD) (NCT06924970) | Agios Pharmaceuticals, Inc. | 2025-05-01 |
| S095033 in Combination With Paclitaxel as 2nd- or 3rd-line Treatment in Participants With Advanced or Metastatic ESCC (NCT05312372) | Institut de Recherches Internationales Servier | 2025-05-01 |
| Gemcitabine and Nab-Paclitaxel Combined With Iparomlimab and Tuvorilimab for Advanced Gallbladder Cancer (NCT07310069) | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 2025-05-01 |
| Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes (NCT06535789) | Jaeb Center for Health Research | 2025-05-01 |
| A Study of Lorigerlimab in Participants With Advanced Solid Tumors (NCT06730347) | MacroGenics | 2025-05-01 |
| Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II) (NCT06958432) | Sixth Affiliated Hospital, Sun Yat-sen University | 2025-05-01 |
| Comparison of Permethrin and Ivermectin in Children Greater Than 6 Yrs Age for Treatment of Scabies (NCT06896929) | Children Hospital and Institute of Child Health, Lahore | 2025-05-01 |
| Multigene Risk Score Combined With Ki-67 Dynamic Assessment in Stratified Neoadjuvant Endocrine Therapy Treatment With or Without CDK4/6 Inhibitors in HR+/HER2- Breast Cancer (NCT06650748) | Peking University | 2025-05-01 |
| Effect of CBD on the Brain (NCT06261450) | Université de Sherbrooke | 2025-05-01 |
| Sintilimab Plus Bevacizumab and Chemotherapy in MSS/pMMR Colorectal With no Liver Metastasis (NCT06973343) | Anhui Provincial Cancer Hospital | 2025-05-01 |
| A First-in-human Study of KY-0301 in Patients With Advanced Solid Tumors. (NCT06928363) | Novatim Immune Therapeutics (Zhejiang) Co., Ltd. | 2025-05-01 |
| A Pilot Study of Efgartigimod for Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP) (NCT06831058) | University of Minnesota | 2025-05-01 |
| Conversion From Unresectable To Resectable Metastatic Colorectal Cancer. (NCT03401294) | University of Saskatchewan | 2025-05-01 |
| Efficacy and Safety of Ixekizumab in Patients with Refractory Guttate Psoriasis (NCT06374979) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-05-01 |