| Dose Optimization of MDMA-Assisted Therapy for PTSD (NCT06418178) | Bronx VA Medical Center | 2025-06-03 |
| Low-dose Immunotherapy in Metastatic and Locally Advanced Colorectal and Gastric MSI/dMMR Cancers (NCT07542262) | Blokhin's Russian Cancer Research Center | 2025-06-03 |
| Phase II Trial Comparison of 3 vs 4 Fractions (BRACHY-FIT). (NCT07022470) | Stanford University | 2025-06-03 |
| Access-H20: Sensor-driven Smart Faucet (NCT07062796) | Old Dominion University | 2025-06-03 |
| A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease (NCT06958536) | Sanofi | 2025-06-03 |
| Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer (NCT05873192) | M.D. Anderson Cancer Center | 2025-06-03 |
| A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation (NCT06682806) | Prelude Therapeutics | 2025-06-03 |
| COgnitioN With VERiciGuat Evaluation in Heart Failure (NCT06601465) | University of Alberta | 2025-06-03 |
| DFT383 in Pediatric Participants With Nephropathic Cystinosis (NCT06910813) | Novartis Pharmaceuticals | 2025-06-02 |
| Timely Integration of Palliative Care in Oncology Care for Patients Referred for Palliative Radiotherapy on Bone Metastases: A Randomized Trial (NCT06805396) | Roxanne Gal | 2025-06-02 |
| IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer (NCT07025889) | Ruijin Hospital | 2025-06-02 |
| Copanlisib and Avelumab as a Maintenance Therapy for Advanced Bladder Cancer (NCT05687721) | VA Office of Research and Development | 2025-06-02 |
| Isatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering Myeloma (NCT06762769) | University College, London | 2025-06-02 |
| Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin (NCT05730283) | Kevin Winthrop | 2025-06-02 |
| Effects of Dapagliflozin, Semaglutide, and Their Combination in Heart Failure Patients With Prosthetic Heart Valves (NCT07610174) | Kafrelsheikh University | 2025-06-02 |
| Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS) (NCT06761170) | Beth Israel Deaconess Medical Center | 2025-06-02 |
| Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma (NCT06839053) | Fred Hutchinson Cancer Center | 2025-06-02 |
| Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis (NCT06998628) | Tanta University | 2025-06-02 |
| Safety and Efficacy of OD-07656 and of Subsequent Vedolizumab Therapy in Moderately to Severely Active Ulcerative Colitis (NCT06850727) | Odyssey Therapeutics | 2025-06-02 |
| Semaglutide for Helping Opioid Recovery (NCT06639464) | Brigham and Women's Hospital | 2025-06-02 |
| Toripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal Cancer (NCT06903858) | Sun Yat-sen University | 2025-06-01 |
| Cannabidiol After Multi-Trauma for Pain and Opioid Therapy (NCT06448923) | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 2025-06-01 |
| Phase Ⅱ Clinical Trial of Cadonilimab Combined With Anti-angiogenic Agents in Metastatic dMMR/MSI-H CRC (NCT07003022) | Fudan University | 2025-06-01 |
| Efficacy and Biomarkers of the Second-line Treatment of Adebelizumab Combined With Irinotecan Liposome in Advanced Small Cell Lung Cancer (NCT07004712) | Peking University Cancer Hospital & Institute | 2025-06-01 |
| The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery (NCT06945926) | Zhejiang University | 2025-06-01 |
| SHR - A1811 Injection in the Treatment of Platinum-sensitive Recurrent Ovarian Cancer (NCT06990516) | Tongji Hospital | 2025-06-01 |
| Comparing Two Doses of Midazolam With Added Dexmedetomidine for Kids Before Surgery (NCT06979791) | Cairo University | 2025-06-01 |
| CD5 CAR T-Cell Therapy for r/r T-cell Lymphomas (NCT07022964) | Beijing GoBroad Hospital | 2025-06-01 |
| Investigation of Growth Hormone and Platelet-Rich Plasma on Joint Health (NCT06907121) | Integrant Pty Ltd | 2025-06-01 |
| Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease ) (NCT07340723) | Daihong Liu | 2025-06-01 |
| Combination of QLS31905, QL2107 and Chemotherapy as First-line Therapy in CLDN18.2-positive Unresectable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (NCT06942767) | Qilu Pharmaceutical Co., Ltd. | 2025-06-01 |
| CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia (NCT06892951) | University Hospital, Tours | 2025-06-01 |
| Study to Evaluate the Safety, Tolerability, and Efficacy of PEP-TISSEEL in Subjects With Chronic Radiation Ulcer (NCT06793748) | Rion Inc. | 2025-06-01 |
| The Efficacy and Safety of Guilu Erxian Jiao in the Treatment of Intradialytic Hypotension (NCT06980922) | Chang Gung Memorial Hospital | 2025-06-01 |
| A Study Evaluating the Safety, Tolerability, and Efficacy of Aramchol Meglumine in Primary Sclerosing Cholangitis (NCT06095986) | Galmed Pharmaceuticals Ltd | 2025-06-01 |
| Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis (NCT06857240) | The Cleveland Clinic | 2025-06-01 |
| Local Metformin Gel and Impacted Lower Third Molar (NCT06975839) | Fayoum University | 2025-06-01 |
| Evaluation of the Effect of Adapted Physical Activity on the Modification of Lipid Metabolism During Chemotherapy for Metastatic COLorectal Cancer (NCT06944548) | Centre Georges Francois Leclerc | 2025-06-01 |
| Stemchymal® for Polyglutamine Spinocerebellar Ataxia (NCT06397274) | Steminent US, Inc. | 2025-06-01 |
| Safety and Efficacy of IB-FOLFIRI in BRAF V600E-Mutant Metastatic Colorectal Cancer (NCT07150247) | Sun Yat-sen University | 2025-06-01 |
| Phase II Study of Platinum (Cisplatin/Carboplatin)and Polymeric Micelles Paclitaxel(Pm-Pac) With Ivonescimab in First Line Metastatic Squamous NSCLC. (NCT07009925) | Jiangsu Cancer Institute & Hospital | 2025-06-01 |
| Gegen Qinlian Tang and Probiotics for Radiation Enteritis (NCT06836960) | Jiujiang No.1 People's Hospital | 2025-06-01 |
| PD-1 Combined With Bevacizumab and PCSK-9 Inhibitor in Patients With Advanced NSCLC Who Have Progressed After Anti- PD- 1/L1 Therapy (NCT07014215) | Anhui Provincial Cancer Hospital | 2025-06-01 |
| Nanocrystalline Megestrol Acetate for the Treatment of Anorexia-Cachexia Syndrome in Extensive-Stage Small Cell Lung Cancer: A Prospective, Open-Label, Single-Arm Phase II Clinical Study (NCT06909383) | Guangzhou Institute of Respiratory Disease | 2025-06-01 |
| Topical Metformin Versus Topical Ketotifen in Melasma Treatment (NCT06942390) | Assiut University | 2025-06-01 |
| Effect of Salidroside on Pregnancy Outcomes in High Childbearing Age Patients in Viro Fertilization (NCT06990685) | The Second Hospital of Shandong University | 2025-06-01 |
| Comparison of Otezla to SFA-002 to Placebo in Plaque Psoriasis Patients (NCT06863493) | SFA Therapeutics | 2025-06-01 |
| Efficacy Test of Curcuminoid Standardized Turmeric Capsules to Improving Inflammatory Biomarkers in Osteoarthritis Genu (NCT07183215) | Gadjah Mada University | 2025-06-01 |
| The Anti-Anginal Effects of N-Acetylcysteine (NAC) in Patients with Angina and Non-Obstructive Coronary Arteries (ANOCA) (NCT06890507) | University of Adelaide | 2025-06-01 |
| Multicenter Study of Combined Chemotherapy and Transplantation for Adult ALL (NCT07059156) | Shanxi Bethune Hospital | 2025-06-01 |
| PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD) (NCT06853912) | Nathan Brashares Sackett | 2025-06-01 |
| The R-E-V-I-V-A-L Study (NCT06992674) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-06-01 |
| The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy (NCT05810311) | Region Stockholm | 2025-06-01 |
| Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC (NCT05608369) | Case Comprehensive Cancer Center | 2025-06-01 |
| Ultrasound-Guided Stellate Ganglion Block in Fibromyalgia (NCT07343128) | Sanliurfa Education and Research Hospital | 2025-06-01 |
| A Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid (NCT06234462) | University of Texas Southwestern Medical Center | 2025-06-01 |
| Magnesium Sulfate and Trigger Points (NCT06975813) | Fayoum University | 2025-06-01 |
| Buccal Fat for Transoral Robotic Lateral Oropharyngectomy Defects to and Postoperative Pain (NCT06965738) | University Health Network, Toronto | 2025-06-01 |
| Zanubrutinib, Chidamide, and Rituximab Induction With or Without CHOP Versus R-CHOP in Newly Diagnosed Double-Expressor DLBCL (NCT06890585) | Li Zhiming | 2025-06-01 |
| Transvaginal Diverticulum Wall Filling and Coverage Technique for Treating Female Circumferential Urethral Diverticulum (NCT07006753) | West China Hospital | 2025-06-01 |
| Immunotherapy Combined With Auto-HSCT and CD22/CD19 CAR-T Sandwich Strategy for B-ALL (NCT06985498) | The First Affiliated Hospital of Soochow University | 2025-06-01 |
| A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC (NCT07002177) | Forward Pharmaceuticals Co., Ltd. | 2025-06-01 |
| Selinexor, High-dose Methotrexate, and Rituximab Combined With Radiotherapy for Newly Diagnosed, Transplant-ineligible Patients With Central Nervous System Lymphoma: An Open-label, Single-arm, Multicenter Phase II Study (NCT07002099) | Second Affiliated Hospital of Soochow University | 2025-06-01 |
| Second-line Regimen Combined With Radiotherapy Versus Without Radiotherapy in Patients With Locally Advanced/Oligometastatic ICC After Failure of First-line Treatment：an Open-label, Randomized, Controlled Phase II Clinical Study (NCT06946849) | Shanghai Zhongshan Hospital | 2025-06-01 |
| Dose-modified Emapalumab and Ruxolitinib (E-Ru) Regimens for Hemophagocytic Lymphohistiocytosis (NCT06951971) | The First Affiliated Hospital of Soochow University | 2025-06-01 |
| Sequential Anti-Angiogenic Therapy After Immunotherapy in Advanced Biliary Tract Cancer (NCT07025174) | First Affiliated Hospital of Zhejiang University | 2025-06-01 |
| Effect of Topical Diltiazem Plus Fusidic Acid Versus Fusidic Acid Alone on Episiotomy Healing, Pain, and Resumption of Sexual Activity: A Randomized Controlled Trial in Azadi Teaching Hospital (NCT07545187) | Alaa Nadhim Hameed | 2025-06-01 |
| Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer (NCT07040098) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-06-01 |
| OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibition (NCT05425576) | Oncotelic Inc. | 2025-06-01 |
| Intravenous Acetaminophen for Postoperative Delirium in Older Patients Recovering From Major Noncardiac Surgery (NCT06653465) | RenJi Hospital | 2025-06-01 |
| A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation (NCT06836024) | Hamilton Health Sciences Corporation | 2025-06-01 |
| Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial (NCT05752149) | Erasmus Medical Center | 2025-06-01 |
| Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01） (NCT06647680) | The Affiliated Hospital of Qingdao University | 2025-06-01 |
| Iparomlimab/Tuvonralimab Combined With Bevacizumab and CAPEOX as Conversion Therapy for Colorectal Cancer Liver Metastasis (NCT07007728) | Peking University Cancer Hospital & Institute | 2025-06-01 |
| Efficacy of Gilteritinib in Combination With FLAI as Induction Therapy of FLT3-positive Acute Myeloid Leukemia (NCT06667973) | Gruppo Italiano Malattie EMatologiche dell'Adulto | 2025-06-01 |
| Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder (NCT06969937) | Dr. med. Marcus Herdener | 2025-06-01 |
| 177Lu-FAP-2286 Treatment in Urethelial Neoplasms: Utility and Safety as a Novel Treatment. (NCT06880757) | Ankara University | 2025-06-01 |
| A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001 (NCT06852963) | PYC Therapeutics | 2025-06-01 |
| Facilitating Neuroplastic Changes of Acute Stroke Survivors (NCT06404268) | University of Maryland, Baltimore | 2025-06-01 |
| CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk (NCT07053462) | AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC | 2025-06-01 |
| Clinical Study of the Safety and Efficacy of ASCT Combined With CD7-CART in the Treatment of CD7+ TCL (NCT07106723) | Institute of Hematology & Blood Diseases Hospital, China | 2025-06-01 |
| Neoadjuvant Therapy With Ivonescimab Combined With Chemotherapy for Triple-Negative Breast Cancer (NCT06977542) | Fudan University | 2025-06-01 |
| a New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia (NCT07007949) | The First Affiliated Hospital of Soochow University | 2025-06-01 |
| CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection (NCT07053488) | AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC | 2025-06-01 |
| Comparison of Effectiveness of Tranexamic Acid Mesotherapy Versus Glutathione Mesotherapy in Post Burn Facial Hyperpigmentation (NCT07263841) | King Edward Medical University | 2025-06-01 |
| Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial (NCT06889363) | Cairo University | 2025-06-01 |
| Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults (NCT05441410) | University Hospital Tuebingen | 2025-06-01 |
| Real-World Joint Outcomes After Selective Transition to Low-Dose Emicizumab in Pediatric Hemophilia A (NCT07439055) | Chulalongkorn University | 2025-06-01 |
| Autologous Bone Marrow Mesenchymal Stem Cell Therapy for Ischemic Stroke (NCT06997939) | Affiliated Hospital of Nantong University | 2025-06-01 |
| Phase II Trial of Anti-PD-1 Antibody Treatment and Radiotherapy in Early-stage Favorable Classic Hodgkin Lymphoma (NCT06916416) | University of Cologne | 2025-06-01 |
| A Multiple Ascending Dose Study of DT-216P2 in Patients With Friedreich's Ataxia (NCT06874010) | Design Therapeutics, Inc. | 2025-06-01 |
| Time Restricted Eating in Haematological Malignancies (NCT06862323) | British Columbia Cancer Agency | 2025-06-01 |
| Low Dose Emicizumab vs Low Dose Factor VIII in Prophylaxis in Hemophilia A Patients (NCT06938659) | Dhaka Medical College | 2025-06-01 |
| A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of QLC1101 in Combination With Other Therapies in the Treatment of Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation (NCT06949761) | Qilu Pharmaceutical Co., Ltd. | 2025-06-01 |
| Study of JSKN016 Combination Therapy in Inoperable Locally Advanced or Metastatic HER2-Negative Breast Cancer (NCT06942234) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2025-06-01 |
| Glofitamab, Polatuzumab Vedotin and Zanubrutinib in First-line Elderly DLBCL (NCT07012980) | Shanghai Zhongshan Hospital | 2025-06-01 |
| The Effectiveness of Herbal Creams Compared to Urea in Dry Skin Treatment (NCT07360639) | Universitas Syiah Kuala | 2025-06-01 |
| A Phase II Study of SHR-A1811 Combined With Radiotherapy in HER2-positive and HER2-low Breast Cancer Brain Metastases (NCT06975462) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-06-01 |
| Investigating the Protective Impact of LY-2940094 on Stress-induced Depression- and Anxiety-related Phenotypes in Humans (NCT06786637) | Mclean Hospital | 2025-06-01 |
| Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases (NCT06311851) | Pardis Noor Medical Imaging and Cancer Center | 2025-06-01 |