| Calcium Channel Blocker Amlodipine for Endometrial Cancer Therapy (NCT06942377) | Peking University People's Hospital | 2025-07-15 |
| Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients (NCT07073092) | Ain Shams University | 2025-07-15 |
| QL1706 Plus Celecoxib in Advanced Esophageal Squamous Cell Carcinoma (NCT07049185) | Peking University Cancer Hospital & Institute | 2025-07-15 |
| A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME) (NCT06963710) | Aligos Therapeutics | 2025-07-15 |
| Evaluation of Tretinoin Cream on the Integrity of Aged Forearm Skin (NCT07084116) | James Thomas Pathoulas | 2025-07-14 |
| Manipulating the Peri-Infarct Area Using Maraviroc to Enhance Motor Skills After Stroke (NCT07080567) | Emmanuel Carrera | 2025-07-14 |
| A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) (NCT07015983) | Juno Therapeutics, Inc., a Bristol-Myers Squibb Company | 2025-07-14 |
| A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases (NCT06764940) | Biostar Pharma, Inc. | 2025-07-14 |
| Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer (NCT06738303) | Case Comprehensive Cancer Center | 2025-07-14 |
| Combined Gamma Knife/Linac Radiosurgery for Large Brain Tumors / Metastases (NCT07162246) | Sunnybrook Health Sciences Centre | 2025-07-14 |
| Comparing Regorafenib Combined With Envafolimab to Physician's Choice in Patients With Metastatic Gastrointestinal Stromal Tumors Harboring KIT Exon 17 Mutations Refractory to Standard Treatment (NCT07559864) | Jian Li | 2025-07-14 |
| Efficacy and Safety Study of Romiplostim N01 for Cancer Treatment-induced Thrombocytopenia (CTIT) in the Treatment of Leukemia (NCT06898983) | Anhui Provincial Hospital | 2025-07-14 |
| Low Dose Radiotherapy for Heart Failure (NCT07037524) | Hospital do Coracao | 2025-07-14 |
| The Effect of 0.01% Atropine Eye Drops on Axial Length and Refraction in Myopic Children Compared to a Control Group (NCT07456488) | Liaquat National Hospital & Medical College | 2025-07-13 |
| Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care (NCT06832722) | 4TEEN4 Pharmaceuticals GmbH | 2025-07-13 |
| Telitacicept for PGNMID: A Single-Arm Study (NCT07111338) | Peking University First Hospital | 2025-07-12 |
| Clinical Trial on Digestive Enzymes: Effects on Post-Meal Response to High-Macronutrient Meals (NCT06949735) | Pancap Pharma Inc. | 2025-07-11 |
| A Trial of SHR-A2102 With Adebrelimab With or Without Other Anti-tumor Therapies in Recurrent/MetastaticHead and Neck Squamous Cell Carcinoma Cancer (NCT07059221) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-07-11 |
| Study of GV20-0251 in Participants With Solid Tumor Malignancies (NCT07070518) | GV20 Therapeutics | 2025-07-11 |
| A Double-Blind, Randomized, Vehicle-Controlled Phase 2 Study to Assess the Efficacy and Safety of GX-03 in Adult Subjects With Moderate to Severe Atopic Dermatitis (Eczema) (NCT07355075) | Turn Therapeutics | 2025-07-11 |
| Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial Treatment (NCT06669572) | University of Chicago | 2025-07-11 |
| Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery (NCT06734975) | Rutgers, The State University of New Jersey | 2025-07-11 |
| Dual EGFR/HER2 Blockade Combined With Irinotecan for the Treatment of HER2-Positive Metastatic Colorectal Cancer (NCT07059338) | Sun Yat-sen University | 2025-07-11 |
| Intravitreal Adalimumab in Inherited and Degenerative Retinal Diseases (NCT07348588) | Centro de Pesquisa Rubens Siqueira | 2025-07-10 |
| SBRT With Immunotherapy and Atezo-Bev in HCC With Major Portal Vein Thrombosis (NCT06823375) | Chinese University of Hong Kong | 2025-07-10 |
| Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV (NCT06554717) | Massachusetts General Hospital | 2025-07-10 |
| A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection (NCT05582694) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-07-10 |
| Assessing the Safety and Efficacy of a Combination Therapy for STH in PSAC in Bangladesh (NCT07045493) | International Centre for Diarrhoeal Disease Research, Bangladesh | 2025-07-10 |
| ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas (NCT06838676) | Nationwide Children's Hospital | 2025-07-10 |
| A Trial of Recaticimab and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable BTC (NCT07062328) | Sun Yat-sen University | 2025-07-10 |
| A Phase II Clinical Study to Evaluate the Efficacy and Safety of Flazoparib Combined With Temozolomide After the Completion of Standard Concurrent Chemoradiotherapy (CCRT) in Newly Diagnosed Glioblastoma (NCT07047066) | Tongji Hospital | 2025-07-10 |
| A Trial of Remimazolam for Intraoperative Sedation in Pediatric and Adolescent Patients (NCT07036419) | Jiangsu HengRui Medicine Co., Ltd. | 2025-07-10 |
| Pucotenlimab Combination With Vorolanib as Neoadjuvant Therapy for ccRCC (NCT07386158) | Sun Yat-sen University | 2025-07-10 |
| A Phase I/II Study of WJB001 Combination Therapy on Safety and Efficacy for Advanced Solid Tumors (NCT06953323) | Wigen Biomedicine Technology (Shanghai) Co., Ltd. | 2025-07-10 |
| Study of HS-10516 Combination Therapy in Patients With Advanced Renal Cell Carcinoma (NCT07097935) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2025-07-10 |
| A Trial of HRS-6213 in Healthy Subjects and Patients With Solid Tumors (NCT07070349) | Jiangsu HengRui Medicine Co., Ltd. | 2025-07-10 |
| Clinical Trial of TJ0113 Capsules in the Treatment of Patients With Depressive Disorder (NCT07018245) | Hangzhou PhecdaMed Co., Ltd. | 2025-07-09 |
| A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG (NCT06892288) | Glycomine, Inc. | 2025-07-09 |
| Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma (NCT07043972) | Fox Chase Cancer Center | 2025-07-09 |
| Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population (NCT06997068) | Mayo Clinic | 2025-07-09 |
| Repurposing Mirtazapine in Rett Syndrome (NCT07430046) | University of Trieste | 2025-07-09 |
| A Clinical Trial to Evaluate the Efficacy and Safety of TQA3605 Tablets in Treatment-naive Chronic HBV-infected Subjects (NCT06990776) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2025-07-09 |
| EGFR Antibody Combined With PD-1 Inhibitor and Chemotherapy in R/M Nasopharyngeal Carcinoma (NCT06802835) | Sun Yat-sen University | 2025-07-09 |
| A Multicenter, Open-Label, Non-Randomized, Single-Arm Clinical Study of Nanobody CD5-CAR T Cell Therapy for Refractory/Relapsed T Lymphocyte Malignancies (NCT07070323) | Beijing GoBroad Hospital | 2025-07-09 |
| Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS (NCT05879484) | National Cancer Institute (NCI) | 2025-07-09 |
| AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases. (NCT06991114) | Artiva Biotherapeutics, Inc. | 2025-07-09 |
| A Dose-finding Study of JMKX003142 in Treatment of Cardiac Edema (NCT06949020) | Jemincare | 2025-07-09 |
| An Outpatient Study of the Efficacy of ARS-2 in Patients With Chronic Spontaneous Urticaria (NCT06927999) | ARS Pharmaceuticals, Inc. | 2025-07-09 |
| Study on the Optimal Combination Pattern of the Combined Treatment of Radiotherapy and Immunotherapy for the Abscopal Effect in Non-Small Cell Lung Cancer (NSCLC) With Multiple Metastases (NCT06953843) | Xinqiao Hospital of Chongqing | 2025-07-09 |
| A Clinical Trial of HRS-7058 Combined Anti-tumor Drugs in Subjects With Solid Tumors (NCT07032077) | Shandong Suncadia Medicine Co., Ltd. | 2025-07-09 |
| Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy (NCT06953882) | Yale University | 2025-07-09 |
| Ablative Radioembolization of Renal Cell Carcinoma Trial (NCT06642220) | Derek W. Cool | 2025-07-09 |
| Efficacy and Safety of Oral Midazolam Used for the Delivery of Care in Elderly Patient With Neurocognitive Disorders and Refusing Care. (NCT06638710) | University Hospital, Grenoble | 2025-07-08 |
| PANK-003 Cell Injection Combined With Standard Adjuvant Chemotherapy After Surgery in Patients With Stage IIIA NSCLC (NCT07043907) | Shenzhen Celconta Life Science Co., Ltd. | 2025-07-08 |
| Stereotactic Body Radiotherapy or Standard of Care for Prostate Oligoprogressive Cancer (NCT06927635) | University Health Network, Toronto | 2025-07-08 |
| Safety and Immunogenicity of a Candidate Rift Valley Fever Vaccine (RVF003) (NCT06799234) | University of Oxford | 2025-07-08 |
| Training Reward Responsiveness Through Virtual Reality (NCT07219875) | University of California, Los Angeles | 2025-07-08 |
| A Trial of SHR-4849 Combined With Other Antitumor Drugs in Patients With Malignant Solid Tumors (NCT07028281) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-07-08 |
| Neoadjuvant Treatment With Atezolizumab and Atezolizumab as Maintenance for the Treatment of Stage III Non Small-Cell Lung Cancer (NSCLC) (NCT07153445) | Fundación GECP | 2025-07-08 |
| Atacicept in Multiple Glomerular Diseases (NCT06983028) | Vera Therapeutics, Inc. | 2025-07-07 |
| Impact of a Medical-Financial Partnership Intervention on Parent Mental Health, Perinatal Outcomes, and Child Developmental Risk (NCT07064915) | University of California, Los Angeles | 2025-07-07 |
| A Randomized Controlled Study of the Efficacy and Safety of Lenalidomide in the Treatment of Active IgG4-related Disease (NCT07068165) | Peking Union Medical College Hospital | 2025-07-07 |
| A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration (NCT07029945) | Biojiva LLC | 2025-07-07 |
| Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML) (NCT07008638) | Masonic Cancer Center, University of Minnesota | 2025-07-07 |
| Assessing the Safety, Immunogenicity and Ex-vivo Efficacy of Two Candidate Malaria Transmission Blocking Vaccines, Pfs25-IMX313 and Pfs45/48 Administered Alone and in Combination, in Matrix-M Adjuvant (NCT06549257) | University of Oxford | 2025-07-07 |
| Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation (NCT06940609) | University of New Mexico | 2025-07-07 |
| Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality (NCT06706232) | The University of Texas Health Science Center, Houston | 2025-07-07 |
| The Safety and Efficacy of GMDTC for Injection in Subjects With Elevated Cadmium Levels (NCT07057414) | Guangdong Jianersheng Pharmaceutical Technology Co., Ltd. | 2025-07-07 |
| Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC) (NCT06904235) | Helsinn Healthcare SA | 2025-07-07 |
| An Exploratory Study on NK Cell-assisted Prevention of Bone Marrow Suppression During Chemotherapy for Ovarian Cancer (NCT07096583) | Anhui Provincial Cancer Hospital | 2025-07-07 |
| A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis (NCT06999733) | Krystal Biotech, Inc. | 2025-07-07 |
| An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC) (NCT06991556) | Novartis Pharmaceuticals | 2025-07-07 |
| Fruquintinib vs Bevacizumab Combined With Irinotecan Liposome and Capecitabine as Second-Line Therapy for Advanced Metastatic Colorectal Cancer (NCT07051785) | Liu Huang | 2025-07-07 |
| A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis (NCT06975722) | Sanofi | 2025-07-07 |
| Trametinib Treatment for Complicated Vascular Anomalies (NCT07072403) | West China Hospital | 2025-07-07 |
| A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients (NCT05803551) | Mayo Clinic | 2025-07-07 |
| Neoadjuvant Tislelizumab in Combination With Nab-Paclitaxel for UTUC (NCT07126119) | Tianjin Medical University Second Hospital | 2025-07-05 |
| Neoadjuvant Tislelizumab + Nab-Paclitaxel Followed by Distal Ureterectomy for Ureteral Cancer (NCT07125547) | Tianjin Medical University Second Hospital | 2025-07-05 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-6452 in Adult Patients With Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Advanced/Metastatic Breast Cancer or Locally Advanced/Metastatic Solid Tumor (NCT07612891) | Shenzhen Ionova Life Sciences Co., Ltd. | 2025-07-04 |
| Low-Dose Radiation + SBRT + Tislelizumab Plus Platinum-based Chemotherapy in Stage ⅡA-ⅢB Non-small Cell Lung Cancer (NCT06877299) | Sichuan University | 2025-07-04 |
| Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy (NCT07036796) | Ain Shams University | 2025-07-04 |
| A Clinical Study to Evaluate the Long-term Safety of HRS-1893 in Hypertrophic Cardiomyopathy (NCT07021963) | Shandong Suncadia Medicine Co., Ltd. | 2025-07-04 |
| Menopur And Rekovelle Combination Study Version 2.0 (NCT06997900) | Clinique Ovo | 2025-07-04 |
| Clinical Study of U32 in Patients With Acute Myeloid Leukemia (NCT07036250) | Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd | 2025-07-03 |
| Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne (NCT07013747) | Sanofi Pasteur, a Sanofi Company | 2025-07-03 |
| Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC (NCT07145450) | Anocca AB | 2025-07-03 |
| A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy (NCT06983158) | Capsida Biotherapeutics, Inc. | 2025-07-03 |
| Prevention of Sacituzumab Govitecan-related Neutropenia in Patients With Metastatic Triple Negative Breast Cancer (NCT06616987) | Yeon Hee Park | 2025-07-03 |
| Early Use of Tacrolimus in HLA-Mismatched Haploidentical Allogeneic Hematopoietic Transplantation With Post-Transplant Cyclophosphamide (NCT06828796) | Northside Hospital, Inc. | 2025-07-03 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability in Participants With Obesity or Overweight With Weight-Related Comorbidities (NCT07002905) | Ascletis Pharma (China) Co., Limited | 2025-07-03 |
| Exploring the Safety and Efficacy of Sacituzumab Tirumotecan Combined With Pucotenlimab in the Treatment of Advanced Cholangiocarcinoma (NCT07105852) | Sir Run Run Shaw Hospital | 2025-07-03 |
| Limited Versus Extended Trophic Feeding (LET-FEED) Trial (NCT06893939) | University of Washington | 2025-07-03 |
| Omalizumab Weight-Based Dosing Efficacy Trial (NCT06943534) | Massachusetts General Hospital | 2025-07-03 |
| A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) (NCT07047118) | Novartis Pharmaceuticals | 2025-07-03 |
| [18F]F-FAPI PET/CT and Laparoscopy in Staging Advanced Gastric Cancer (NCT07018661) | Leiden University Medical Center | 2025-07-03 |
| A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02) (NCT06863272) | Merck Sharp & Dohme LLC | 2025-07-03 |
| Phase II Biomarker Study of BND-22 in Combination With Cemiplimab in Solid Tumors (NCT06651593) | M.D. Anderson Cancer Center | 2025-07-02 |
| Lenvatinib Plus Tislelizumab Versus Lenvatinib Alone in Hepatocellular Carcinoma Previously Treated With Anti-PD1/PD-L1 and Bevacizumab (NCT07047586) | Fudan University | 2025-07-02 |
| Study Investigating Tarlatamab (AMG 757) in Patients With Metastatic/Locally Advanced Small-Cell Lung Cancer (SCLC) and Other Poorly Differentiated Neuroendocrine Carcinomas (NECs), With Biomarker Analysis to Characterize Response/Resistance (UNLOCK TARLATAMAB) (NCT07016230) | Gustave Roussy, Cancer Campus, Grand Paris | 2025-07-02 |
| Ketamine and Levetiracetam as Second-line Antiseizure Medication for Status Epilepticus in Children (NCT07046611) | Sohag University | 2025-07-02 |