| Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type (NCT06052254) | Teikoku Pharma USA, Inc. | 2025-09-16 |
| Sex Differences in NMDA-enhancing Treatment of Schizophrenia (NCT07122895) | China Medical University Hospital | 2025-09-16 |
| Intra-arterial Selective Hypothermic Magnesium Sulfate Infusion in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke (NCT07163299) | Capital Medical University | 2025-09-15 |
| PCSK9 Inhibitors in Acute Ischemic Stroke Patients Undergoing Endovascular Therapy (NCT07174375) | Nanfang Hospital, Southern Medical University | 2025-09-15 |
| Venetoclax Plus Hypomethylating Agents and Subcutaneous Cytarabine for CEBPA-Mutated AML (NCT07451912) | The First Affiliated Hospital of Soochow University | 2025-09-15 |
| Hypofractionated Radiotherapy Combined With Immunochemotherapy for Conversion Treatment of Gastroesophageal Junction Adenocarcinoma (NCT07072351) | West China Hospital | 2025-09-15 |
| Clinical Evaluation of Photobiomodulated Hyaluronic Acid Therapy for Interdental Papillary Loss: Minimal Invasive Blind Split Mouth Technique (NCT07012525) | Dar Al Uloom University | 2025-09-15 |
| Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (NCT07115485) | Shanghai Henlius Biotech | 2025-09-15 |
| Relmacabtagene Autoleucel Combined With Sintilimab for Relapsed/Refractory B-cell Lymphoma (NCT07077512) | Sun Yat-sen University | 2025-09-15 |
| Camrelizumab, Pirfenidone, and Chemotherapy in the Treatment of Advanced Triple-Negative Breast Cancer (NCT07161791) | Harbin Medical University | 2025-09-15 |
| Proof of Concept Study on BP1.4979 Effect on Primary Premature Ejaculation (NCT07047404) | Bioprojet | 2025-09-15 |
| Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects With Advanced Colorectal Cancer (NCT07106892) | Shanghai Henlius Biotech | 2025-09-15 |
| Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension (NCT07090161) | Vanda Pharmaceuticals | 2025-09-15 |
| Romiplostim N01 for the Treatment of Thrombocytopenia Associated With Radiotherapy-Combined Treatment Regimens in Patients With Solid Tumors (NCT07128576) | Zhujiang Hospital | 2025-09-15 |
| Etoposide Capsules Combined With Bevacizumab and Iparomlimab and Tuvonralimab in the Treatment of Platinum Resistant or Platinum Refractory Ovarian Cancer (NCT07117877) | Fudan University | 2025-09-15 |
| EFFECTS OF A FULL SPECTRUM CANNABIS EXTRACT WITH DIFFERENT DOSES OF CBD AND THC ON THE MODULATION OF FIBROMYALGIA: A PILOT, MULTICENTER, OPEN LABEL CLINICAL TRIAL (FRIDINHA) (NCT07498023) | Federal University of Latin American Integration | 2025-09-15 |
| Sintilimab Combined With Anlotinib and Taxane-Based Chemotherap for Recurrent/Metastatic Nasopharyngeal Carcinoma (NCT07581821) | Ming-Yuan Chen | 2025-09-15 |
| Study of Tirzepatide for Recovery and Alcohol Use Management (NCT06727331) | Brigham and Women's Hospital | 2025-09-15 |
| Empagliflozin as a Potential Therapeutic Solution for Patients With Brugada Syndrome (NCT07146880) | National Taiwan University Hospital | 2025-09-15 |
| HB1801 Combined Treatment of HER2-positive Breast Cancer (NCT07116824) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2025-09-15 |
| Exploration of the Efficacy and Mechanism of Galantamine (an Extract From Lycoris Aurea) in Treating Ischemic Stroke (NCT07003386) | Shanghai Yueyang Integrated Medicine Hospital | 2025-09-15 |
| Linperlisib Combined With Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma (NCT07139353) | Sun Yat-sen University | 2025-09-15 |
| A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy (NCT07047144) | Scholar Rock, Inc. | 2025-09-15 |
| Phase II Clinical Trial of Lyophilized Respiratory Syncytial Virus mRNA Vaccine in Adults Aged 50 Years or Above (NCT07289542) | Suzhou Abogen Biosciences Co., Ltd. | 2025-09-15 |
| N-Acetylcysteine Roles in Preserving Renal Function Measured by Urinary KIM-1 (Kidney Injury Molecule-1) and Serum Creatinine on Cancer Patients With Cisplatin Based Chemotherapy: A Randomized Placebo-Controlled Trial (NCT07156786) | Fakultas Kedokteran Universitas Indonesia | 2025-09-15 |
| Allogeneic Umbilical Cord Mesenchymal Stromal Cells for the Treatment of Chronic Antibody-Mediated Rejection in Kidney Transplantation (NCT06886646) | Assistance Publique - Hôpitaux de Paris | 2025-09-15 |
| Developing a New LIFU Neuromodulation Method to Suppress Tremor (NCT07103265) | University of Calgary | 2025-09-15 |
| Sirolimus Discontinuation Strategies in Kaposiform Hemangioendothelioma (NCT07131644) | West China Hospital | 2025-09-13 |
| Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant (NCT07079735) | Columbia University | 2025-09-12 |
| A Study in Subjects With Neurogenic Orthostatic Hypotension (NCT07089043) | CuraSen Therapeutics, Inc. | 2025-09-12 |
| SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC (NCT07284992) | Shandong Provincial Hospital | 2025-09-12 |
| A Study to Investigate the Efficacy and Safety of Two Different Doses of Twice Daily Distal Jejunal-release Dextrose Beads Formulations Combined With a Gel Composition Compared to Placebos in Obese Subjects With Weight Related Comorbidities (NCT07008456) | Aphaia Pharma US LLC | 2025-09-12 |
| Ex Vivo Drug Response Evaluation for Next Generation Care of Brain Metastases (NCT06620380) | University of Zurich | 2025-09-12 |
| Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations (NCT07032727) | M.D. Anderson Cancer Center | 2025-09-12 |
| Total Neoadjuvant Therapy for Lymph Node-positive Adenocarcinoma of the OESophagus and Oesophagogastric Junction (NCT06161818) | Erasmus Medical Center | 2025-09-12 |
| A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer) (NCT06822543) | Latin American Cooperative Oncology Group | 2025-09-12 |
| ASKC200 for Knee Osteoarthritis Pain (NCT07742852) | Jiangsu Aosaikang Pharmaceutical Co., Ltd. | 2025-09-12 |
| A Trial of HRS-4508 in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NCT07003321) | Jiangsu HengRui Medicine Co., Ltd. | 2025-09-12 |
| A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO (NCT07205887) | EyeBiotech Ltd. | 2025-09-12 |
| Phase II Study of QLS32015 Combination Therapy in the Treatment of Multiple Myeloma (NCT07018050) | Qilu Pharmaceutical Co., Ltd. | 2025-09-12 |
| Dalpiciclib With or Without Entinostat and Letrozole in HR+/HER2- Early Breast Cancer (NCT07492394) | Hebei Medical University Fourth Hospital | 2025-09-12 |
| Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy (NCT07245095) | Hospital General de Mexicali | 2025-09-12 |
| A Study Evaluating 24 Months of Lithium Carbonate Treatment in Patients With TBR1-related Neurocognitive Disorder (NCT06776848) | Centre Hospitalier Universitaire Dijon | 2025-09-12 |
| PCV24 Clinical Trial in Infants and Young Children Aged 2 Months (Minimum 6 Weeks) to 71 Months (NCT07333352) | Reinovax Biologics Co., LTD | 2025-09-11 |
| Phase II Trials of Letermovir Prophylaxis in Patients With RRMM Undergoing Elranatamab Therapy (NCT06920251) | Seoul National University Hospital | 2025-09-11 |
| Belumosudil for Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation (NCT06751602) | The Methodist Hospital Research Institute | 2025-09-11 |
| An Open-label Study of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC (NCT06894511) | Novartis Pharmaceuticals | 2025-09-11 |
| A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01) (NCT06926868) | Bristol-Myers Squibb | 2025-09-11 |
| A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis (NCT07013201) | LEO Pharma | 2025-09-11 |
| Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age (NCT07207408) | Dynavax Technologies Corporation | 2025-09-11 |
| SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma (NCT07049848) | M.D. Anderson Cancer Center | 2025-09-11 |
| Xinlikang Capsule for Chemotherapy-induced Fatigue and Immune Disorders in Diffuse Large B Lymphoma (NCT07084662) | Sun Yat-sen University | 2025-09-11 |
| Y-90 Treatment Response Using Transarterial Radioembolization (NCT07145801) | Thomas Jefferson University | 2025-09-11 |
| A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex (NCT07027345) | BioMendics, LLC | 2025-09-11 |
| A Clinical Study on the Safety, Tolerability and Efficacy of Neoantigen-based Personalized mRNA Therapy iNeo-Vac-R01 Plus PD-1 Inhibitor in Adjuvant Treatment of Liver Cancer Post Radical Resection (NCT07495215) | Yinghua Xu | 2025-09-11 |
| NexCAR19 (Talikabtagene Autoleucel) in Relapsed/Refractory B-Cell Malignancies (NexCAR19) (NCT07502118) | Health Institutes of Turkey | 2025-09-11 |
| Individualizing Approaches to Surveillance Mammography in Older Breast Cancer Survivors - The I-MAMMO Study (NCT07123649) | Dana-Farber Cancer Institute | 2025-09-11 |
| Evaluation of the Safety, Tolerability and Efficacy of iNeo-Vac-R01, an Individualized mRNA Therapeutic Technology Based on Tumor Neoantigens, for Adjuvant Treatment in Patients With Biliary Malignant Tumors After Radical Resection (NCT07368803) | Yifan Wang | 2025-09-11 |
| MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study) (NCT05783817) | Carolyn Rodriguez | 2025-09-10 |
| Gecacitinib Combined With Donafenib and PD-1 Inhibitor as Immune Rechallenge Therapy for Unresectable Hepatocellular Carcinoma (NCT07157306) | Tianjin Medical University Cancer Institute and Hospital | 2025-09-10 |
| Secondary Cytoreductive Surgery After Chemotherapy for Recurrent Epithelial Ovarian Cancer (NCT07171528) | National Cancer Center, Korea | 2025-09-10 |
| Maintenance Therapy in HER2-Positive Unresectable Locally Recurrent or Metastatic Breast Cancer: A Phase II Study (NCT07179939) | Fudan University | 2025-09-10 |
| Prospective Multicenter Single-arm Trial: AK112 + Nab-paclitaxel/Carboplatin Neoadjuvant for TNBC (NCT07103447) | Shuangyue Liu | 2025-09-10 |
| Safety and Efficacy of TollB-001 Tablets in Moderate to Severe Rheumatoid Arthritis (NCT07408024) | Toll Biotech Co. Ltd. (Beijing) | 2025-09-10 |
| Orelabrutinib Plus Lisaftoclax and Rituximab in Untreated Mantle Cell Lymphoma With High-Risk Disease (NCT07272499) | Ruijin Hospital | 2025-09-10 |
| Pembrolizumab and Odetiglucan in Liver Predominant Metastatic Colorectal Adenocarcinoma (NCT07082439) | Abramson Cancer Center at Penn Medicine | 2025-09-10 |
| Amplitude-Modulated Radiofrequency Electromagnetic Fields (AM RF EMF) in Combination With Fruquintinib in Refractory Metastatic Colorectal Cancer (NCT07130903) | Barbara Ann Karmanos Cancer Institute | 2025-09-10 |
| Primary Tumor Resection With Sintilimab and Chemotherapy in Advanced NSCLC (NCT07177105) | Jianxing He | 2025-09-10 |
| Safety and Immunogenicity of the Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented and Adjuvanted) in Adults and Older Adults (NCT06842173) | Butantan Institute | 2025-09-10 |
| A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma (NCT06753747) | West China Hospital | 2025-09-10 |
| Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma (NCT06528769) | Gabriel Tinoco | 2025-09-10 |
| Melatonin Therapy for Improving ICSI Outcomes in Women With Diminished Ovarian Reserve (NCT07318974) | Benha University | 2025-09-10 |
| CVL006 Combination Therapy in Advanced Solid Tumors (NCT07157956) | Convalife (Shanghai) Co., Ltd. | 2025-09-10 |
| A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis Pigmentosa (NCT07174726) | Beacon Therapeutics | 2025-09-10 |
| A Clinical Study Evaluating HAIC Combined With Iparomlimab and Tuvonralimab Injection Plus Bevacizumab in Patients With Initially Potentially Resectable Hepatocellular Carcinoma (ITBHaic Study) (NCT07119931) | Tianjin Medical University Cancer Institute and Hospital | 2025-09-10 |
| Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia (NCT06599762) | University of Manitoba | 2025-09-10 |
| Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease (NCT07113743) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-09-10 |
| DLL3 CAR-T Therapy Targeting Brain Tumors (NCT07180927) | Shenzhen Geno-Immune Medical Institute | 2025-09-10 |
| A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies (NCT06690281) | National Cancer Institute (NCI) | 2025-09-09 |
| Propranolol Treatment for Postoperative Chylothorax (NCT06833320) | June Wu | 2025-09-09 |
| Eculizumab For the Acute Attack of Neuromyelitis Optica Spectrum Disorder (NCT07184840) | Tianjin Medical University General Hospital | 2025-09-09 |
| Gii'Igoshimong: Sitting With Your First Family (NCT07075081) | Johns Hopkins Bloomberg School of Public Health | 2025-09-09 |
| Spine Radiosurgery for Symptomatic Metastatic Neoplasms (NCT05617716) | University of Oklahoma | 2025-09-09 |
| A Study of Navlimetostat (BMS-986504) in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion (MountainTAP-9) (NCT06855771) | Bristol-Myers Squibb | 2025-09-09 |
| Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma (NCT07096362) | University of Miami | 2025-09-09 |
| Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. (NCT07363603) | Pirogov Russian National Research Medical University | 2025-09-09 |
| 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection (NCT06503146) | National Cancer Institute (NCI) | 2025-09-09 |
| A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer (NCT07054190) | Hoffmann-La Roche | 2025-09-09 |
| A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer (NCT06410534) | National Cancer Institute (NCI) | 2025-09-09 |
| a Phase 1b/2a Study of JMT202 Injection in Participants With Hypertriglyceridemia (NCT07140809) | Shanghai JMT-Bio Inc. | 2025-09-09 |
| A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas (NCT07014137) | University Health Network, Toronto | 2025-09-09 |
| Neoadjuvant Darolutamide Alone or in Combination With Standard Therapy for Stage II-IIIA, AR+, TNBC (NCT07016399) | Vandana Abramson | 2025-09-09 |
| Evaluation of Obicetrapib on Antioxidant Levels in Plasma and HDL Particles of Healthy Volunteers (NCT06982508) | NewAmsterdam Pharma | 2025-09-09 |
| Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis (NCT06764966) | CAMC Health System | 2025-09-09 |
| Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer (NCT04107077) | University of Chicago | 2025-09-09 |
| Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC (NCT07038629) | Tianjin Medical University Cancer Institute and Hospital | 2025-09-08 |
| A Study to Evaluate the Efficacy and Safety of CS32582 in Participants With Moderate to Severe Plaque Psoriasis (NCT07129382) | Chipscreen Biosciences, Ltd. | 2025-09-08 |
| Randomized Adaptive Platform Trial of Pathogen-Directed Anti-inflammatory Therapy in Severe Community-Acquired Pneumonia(Core Protocal) (NCT07152587) | Qingyuan Zhan | 2025-09-08 |
| Primary Tumor Resection Plus Osimertinib in Advanced EGFR-mutant Non-small Cell Lung Cancer (NCT07177092) | Jianxing He | 2025-09-08 |
| Exploration of the Application of Methotrexate-loaded Drug Vesicles in Intrathecal Injection for Meningeal Metastasis of Lung Cancer (NCT07559097) | Henan Cancer Hospital | 2025-09-08 |