| Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism (NCT07530705) | Peking Union Medical College Hospital | 2025-11-17 |
| Compare Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided ACB for Postoperative Analgesia After Knee Surgeries (NCT07240402) | Kafrelsheikh University | 2025-11-17 |
| Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial (NCT06811116) | National Cancer Institute (NCI) | 2025-11-17 |
| Pirtobrutinib and Mosunetuzumab for the Treatment of Relapsed/Refractory Grades 1-3A Follicular Lymphoma, PROMOTE-FL Trial (NCT06948786) | University of Washington | 2025-11-17 |
| A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors (NCT06887803) | iOnctura | 2025-11-17 |
| Evaluate the Safety, Tolerability, and Preliminary Efficacy of EVM14 Alone and in Combination in Patients With Selected Solid Tumors (NCT07095868) | Everest Medicines (Beijing) Co., Ltd. | 2025-11-17 |
| Sintilimab Combined With Bevacizumab Biosimilar as Adjuvant Treatment After Resection of Ruptured Hepatocellular Carcinoma (CLEAR-2) (NCT07331883) | Ruijin Hospital | 2025-11-17 |
| Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC) (NCT07023432) | M.D. Anderson Cancer Center | 2025-11-17 |
| ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer (NCT07198724) | Kristina A. Fanucci | 2025-11-17 |
| BabySTrong II taVNS Feeding Trial (NCT07049952) | Medical University of South Carolina | 2025-11-16 |
| SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome (NCT07214818) | Mansoura University | 2025-11-15 |
| Phase II Clinical Trial of Lyophilized Herpes Zoster mRNA Vaccine in Adults Aged 40 Years or Above (NCT07285278) | Suzhou Abogen Biosciences Co., Ltd. | 2025-11-15 |
| QL1706 Combined With Chemotherapy and Anlotinib for the Treatment of Recurrent Ovarian Cancer (NCT07286240) | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | 2025-11-15 |
| Nimotuzumab Combined With Toripalimab and Chemotherapy for Locally Advanced Tonsillar Cancer (NCT07353723) | Tang-Du Hospital | 2025-11-15 |
| Improving Walking After Spinal Cord Injury (NCT07223710) | Shirley Ryan AbilityLab | 2025-11-15 |
| N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis (NCT07262554) | Alexandria University | 2025-11-15 |
| Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER) (NCT07313241) | University of Texas Southwestern Medical Center | 2025-11-14 |
| ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response (NCT07284667) | ACADIA Pharmaceuticals Inc. | 2025-11-14 |
| Trial of Neoadjuvant THP vs TCHP for HER2-Amplified/Positive Breast Cancer (NCT07220135) | University of Kansas Medical Center | 2025-11-14 |
| Durvalumab and Tremelimumab With or Without Hepatic Arterial Infusion of Chemotherapy in Hepatocellular Carcinoma (NCT06904170) | UNICANCER | 2025-11-14 |
| PULSAR in Systemic Therapy for Pancreatic Cancer (NCT07269626) | Samsung Medical Center | 2025-11-14 |
| Optimal Methods to Characterize ADC Resistance in Solid Tumors and Identify Clinically Useful Biomarkers (NCT07259226) | UNICANCER | 2025-11-14 |
| GKL-006 Injection Plus TACE Versus TACE Alone in Patients With Unresectable Hepatocellular Carcinoma (NCT07209813) | Beijing Gene Key Life Technology Co., Ltd | 2025-11-14 |
| Bright Light Therapy for Depressed Geriatric Inpatients (NCT07002554) | Medical University of South Carolina | 2025-11-14 |
| A Study to Assess Anktiva in Patients With Long Covid-19. (NCT07108036) | ImmunityBio, Inc. | 2025-11-14 |
| A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors (NCT07241936) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2025-11-13 |
| A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS) (NCT07074886) | Hoffmann-La Roche | 2025-11-13 |
| A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer (NCT07059845) | AbbVie | 2025-11-13 |
| Sac-TMT Plus KL-A167 in PD-L1+, HR+/HER2- Metastatic Breast Cancer After CDK4/6 Inhibitors (NCT07258108) | Sun Yat-sen University | 2025-11-13 |
| A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS. (NCT07228390) | Pfizer | 2025-11-13 |
| A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment (NCT07036523) | Boehringer Ingelheim | 2025-11-13 |
| A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC (NCT07255664) | CuraCell TX AB | 2025-11-13 |
| A Study to Investigate the Effect of AZD0780 Tablets in Combination With Rosuvastatin Tablets on Low Density Lipoprotein Cholesterol Levels (LDL-C) in Adult Participants With Dyslipidaemia (NCT07218900) | AstraZeneca | 2025-11-13 |
| Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis (NCT07202598) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-11-12 |
| Cabergoline for Episodic Migraine (NCT07072910) | Aarhus University Hospital | 2025-11-12 |
| First-in-human Study of 7MW4911 in Patients With Advanced Solid Tumors (NCT07265622) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2025-11-12 |
| Precision Administration of Anti-thymocyte Globulin With or Without Verapamil (NCT06455319) | University of Florida | 2025-11-12 |
| A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression (NCT07023627) | Incyte Corporation | 2025-11-12 |
| Maintenance Zanzalintinib With Etoposide After HDCT in GCT (NCT06937866) | Indiana University | 2025-11-12 |
| Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia (NCT07109219) | AstraZeneca | 2025-11-12 |
| RYZ101 for the Treatment of Progressive or Recurrent Intracranial Meningioma (NCT07150806) | Joshua Palmer | 2025-11-12 |
| A Study of Efgartigimod in Patients With IgG4-Related Disease (NCT07025330) | Stanford University | 2025-11-12 |
| Study to Evaluate the Efficacy and Safety of Neo-Adjuvant TACE and Atezolizumab Plus Bevacizumab Therapy for High-Risk Recurrent Hepatocellular Carcinamo (NCT07239245) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-11-12 |
| Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV (NCT06935838) | University of Hawaii | 2025-11-12 |
| A Phase II Clinical Study of FH-006 for Injection Combined With Other Anticancer Therapies in Subjects With Lung Cancer (NCT07241767) | Jiangsu HengRui Medicine Co., Ltd. | 2025-11-12 |
| Anbalcabtagene Autoleucel in Relapsed/Refractory CNS Lymphoma (NCT07062627) | Hyungwoo Cho | 2025-11-12 |
| Evaluation of NWRD08 for HPV-16 and/or HPV-18 Related Cervical HSIL (NCT07175662) | Newish Biotech (Wuxi) Co., Ltd. | 2025-11-11 |
| PRGN-2009 in Combination With Pembrolizumab in Patients With Recurrent or Metastatic Cervical Cancer (NCT06157151) | Precigen, Inc | 2025-11-11 |
| Study of Relapsed/ Refractory B-cell Non- Hodgkin Lymphoma (NCT07125872) | ImmunityBio, Inc. | 2025-11-11 |
| Lenvatinib in Combination With Nivolumab Plus Chemotherapy in Metastatic Gastric Cancer Patients With Malignant Ascites (NCT07149090) | Asan Medical Center | 2025-11-11 |
| A Phase II Study of PEG-rhGH Injection for Short Children Born Small for Gestational Age: Efficacy, Safety, and Pharmacokinetics (NCT07260500) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2025-11-11 |
| Study of Co-administered (Types 1 & 2) Novel Oral Poliomyelitis Vaccines Evaluation (NCT06895486) | PATH | 2025-11-11 |
| Iparomlimab/Tuvonralimab Injection Plus CCRT in LACC (NCT07232654) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-11-11 |
| A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL) (NCT07231952) | Memorial Sloan Kettering Cancer Center | 2025-11-11 |
| MRI-Guided Neoadjuvant Treatment De-Escalation in Stage II-III TNBC (NCT07327021) | Tel-Aviv Sourasky Medical Center | 2025-11-11 |
| Safety and Efficacy of hUC-MSC for the Treatment of Cartilage Damage in the Knee Joint (NCT06981741) | BIONCaRT GmbH | 2025-11-10 |
| Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body (NCT06820957) | Children's Oncology Group | 2025-11-10 |
| A Clinical Trial of Soluble Fiber for Asthma (NCT06372249) | Phoenix Children's Hospital | 2025-11-10 |
| Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers (NCT07396376) | Eluciderm Inc | 2025-11-10 |
| LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis: (NCT07186101) | Eli Lilly and Company | 2025-11-10 |
| Coenzyme Q10 for Neuroprotection in Paclitaxel-Induced Neuropathy (NCT07307911) | Damanhour University | 2025-11-10 |
| Vinpocetine in Patients With Parkinsonian Disease (NCT07229664) | Tanta University | 2025-11-10 |
| Phase 2 Study of ADX-038 in Participants With Geographic Atrophy (NCT06990269) | ADARx Pharmaceuticals, Inc. | 2025-11-10 |
| Sodium Bicarbonate in Intra-dialytic Hypertension in Chronic Hemodialysis Patients (NCT07231900) | Assaf-Harofeh Medical Center | 2025-11-10 |
| Metformin in Parkinson Disease (NCT07229651) | Tanta University | 2025-11-10 |
| Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study) (NCT06983080) | Centre hospitalier de l'Université de Montréal (CHUM) | 2025-11-10 |
| A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489 (NCT07073820) | Pfizer | 2025-11-10 |
| Steroid Treatment for Elimination of Rebound Obstruction From Intranasal Decongestants (NCT07168148) | Washington University School of Medicine | 2025-11-10 |
| GP350 CAR-T for Relapse/Refractory and Epstein-Barr Virus Infection Associated Lymphoid Neoplasms (NCT07306156) | Zhimin Zhai | 2025-11-10 |
| Neoadjuvant SBRT and Tislelizumab (Immunotherapy) Plus Anlotinib for Resectable EGFR Wild-type NSCLC (NCT07231575) | Sun Yat-sen University | 2025-11-10 |
| A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma (NCT07085338) | St. Jude Children's Research Hospital | 2025-11-10 |
| A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO) (NCT07156578) | Rhythm Pharmaceuticals, Inc. | 2025-11-10 |
| Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis (NCT07220577) | Novartis Pharmaceuticals | 2025-11-10 |
| Prostate Androgen Response Investigation Using a Stratification BIOmarker; Predicting Prostate Cancer Downstaging by Neoadjuvant Darolutamide With PCAI ImmunoScore (NCT07617272) | Region Stockholm | 2025-11-09 |
| Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments (NCT07154511) | Prabesh Kanel | 2025-11-07 |
| Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients (NCT07173101) | University of Utah | 2025-11-07 |
| Efficacy and Safety of ACC017 Tablets Compared With Dolutegravir Sodium Tablets in Treatment-Naïve Adults With Human Immunodeficiency Virus Type 1 (HIV-1) (NCT07711223) | Jiangsu Aidea Pharmaceutical Group Co., Ltd. | 2025-11-07 |
| A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy (NCT07227636) | Memorial Sloan Kettering Cancer Center | 2025-11-07 |
| Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial (NCT07123961) | Children's Hospital of Philadelphia | 2025-11-07 |
| A Study to Investigate the Efficacy and Safety of SHR-1905 in Patients With Moderate-to-severe Atopic Dermatitis (NCT07211542) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2025-11-07 |
| Teclistamab-Daratumumab in AL Amyloidosis (NCT07110844) | Rajshekhar Chakraborty, MD | 2025-11-07 |
| Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion (NCT07259928) | Annexin Pharmaceuticals AB | 2025-11-07 |
| Early Phase Study of KESONOTIDE™in Participants With Solid Tumours (NCT06926075) | Filamon LTD | 2025-11-07 |
| Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas (NCT07110246) | University of California, San Francisco | 2025-11-07 |
| Adjuvant Chemotherapy +/- Cemiplimab and Sequential Hypofractionated Radiotherapy in Unfit or Elderly Patients With Stage III Lung Cancer (NCT06656598) | Intergroupe Francophone de Cancerologie Thoracique | 2025-11-07 |
| Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias (NCT05509582) | National Heart, Lung, and Blood Institute (NHLBI) | 2025-11-07 |
| Smoking Cessation Trial in Recurrent Acute Pancreatitis and Chronic Pancreatitis (NCT07171112) | Mayo Clinic | 2025-11-06 |
| Improving Vaccine Protection for Adults (NCT07527247) | Singapore General Hospital | 2025-11-06 |
| Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa (NCT07170917) | Sanofi | 2025-11-06 |
| Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study (NCT06769126) | SWOG Cancer Research Network | 2025-11-06 |
| A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma (NCT07015242) | Juno Therapeutics, Inc., a Bristol-Myers Squibb Company | 2025-11-06 |
| Personalized Antisense Oligonucleotide for A Single Participant (nL62541) With ATN1 Gene Mutation (NCT07221760) | n-Lorem Foundation | 2025-11-06 |
| A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization (NCT07088926) | AstraZeneca | 2025-11-06 |
| A Phase 2 Platform Study of Immunomodulatory Compounds in ICI-refractory Non-small Cell Lung Cancer (NCT07133425) | M.D. Anderson Cancer Center | 2025-11-06 |
| A Phase IIa, Randomized, Double-Blind, Placebo-Controlled Trial of JKN2403 in COPD (NCT07351734) | Joincare Pharmaceutical Group Industry Co., Ltd | 2025-11-06 |
| An Imaging Study of Anti-GD2-800CW in Patients With Neuroblastoma (NCT07399821) | Princess Maxima Center for Pediatric Oncology | 2025-11-05 |
| Adaptive Adjuvant Sintilimab Therapy Guided by MRD (ADAPT Lung) (NCT07120698) | Guangdong Association of Clinical Trials | 2025-11-05 |
| Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain (NCT07053774) | Wake Forest University Health Sciences | 2025-11-05 |
| A Clinical Study of QLC5508 and/or QLH12016 in Combination With Other Anti-tumor Therapies in Subjects With Advanced Prostate Cancer (NCT07198633) | Qilu Pharmaceutical Co., Ltd. | 2025-11-05 |
| Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity (NCT05933499) | Massachusetts General Hospital | 2025-11-05 |