| Mitoxantrone Hydrochloride Liposome and Enlonstobart Combination Treatment in Patients With Relapsed or Refractory Peripheral T Cell Lymphoma (PTCL) (NCT07288814) | Sun Yat-Sen University Cancer Center | 2025-12-08 |
| A Study of Subcutaneous Blinatumomab in Children With R/R and and MRD+ B-Cell Precursor Acute Lymphoblastic Leukemia (NCT07134088) | Amgen | 2025-12-08 |
| A Study of SHR3680, HS-20093 and SHR2554 in Subjects With Prostate Cancer (NCT07230106) | Jiangsu HengRui Medicine Co., Ltd. | 2025-12-08 |
| CMTS0515-auWMT for Radiation Enteritis (NCT07331688) | The Second Hospital of Nanjing Medical University | 2025-12-08 |
| Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma (NCT07097363) | University of Washington | 2025-12-07 |
| This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction (NCT06853223) | University of California, San Francisco | 2025-12-07 |
| Phase II Clinical Study of Probiotic LR607 in Patients With Non-Small Cell Lung Cancer (NCT07534033) | Zhujiang Hospital | 2025-12-06 |
| A Polypill for Acute Coronary Syndrome (NCT07032389) | University of Texas Southwestern Medical Center | 2025-12-05 |
| Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children (NCT07193719) | Charite University, Berlin, Germany | 2025-12-05 |
| Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis (NCT07400965) | Glaukos Corporation | 2025-12-05 |
| Effect of TXA on Reducing Bruising After Filler Injection (NCT06665594) | University of Wisconsin, Madison | 2025-12-05 |
| Safety and Tolerability of a mRNA Vaccine Encoding Tumor-Specific Circular RNA Antigens in Combination With Anti-PD-1 Monoclonal Antibody in Patients With Advanced Solid Tumors (NCT07245901) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2025-12-05 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours (NCT07213817) | Ipsen | 2025-12-05 |
| Intermittent Versus Continuous Venetoclax With Acalabrutinib for CLL/SLL (NCT07014917) | Zulfa Omer | 2025-12-05 |
| A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure. (NCT07222917) | AstraZeneca | 2025-12-05 |
| FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy (NCT06917313) | Yale University | 2025-12-05 |
| Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE) (NCT07443202) | Tarsus Pharmaceuticals, Inc. | 2025-12-05 |
| Cannabis (THC vs. CBD) in Multiple Sclerosis (NCT06261489) | University of Calgary | 2025-12-05 |
| A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE) (NCT07193550) | M.D. Anderson Cancer Center | 2025-12-05 |
| A Trial of SHR0302 Tablets and SHR0302 Base Gel in Patients With Non-segmental Vitiligo (NCT07251595) | Jiangsu HengRui Medicine Co., Ltd. | 2025-12-05 |
| Novel Treatment of Radiation Associated Dysphagia With Statins (NCT07217938) | Peter MacCallum Cancer Centre, Australia | 2025-12-05 |
| A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC (NCT07226986) | Novartis Pharmaceuticals | 2025-12-05 |
| Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial (NCT07178301) | Northwestern University | 2025-12-05 |
| Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma (NCT07339488) | Chuangzhen Chen | 2025-12-05 |
| A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors) (NCT07137598) | Hoffmann-La Roche | 2025-12-05 |
| Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander Challenge (NCT06069063) | Allergy & Asthma Medical Group & Research Center | 2025-12-05 |
| A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD (NCT07275840) | Innovent Biologics Technology Limited (Shanghai R&D Center) | 2025-12-05 |
| Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) (NCT07266155) | Longbio Pharma | 2025-12-05 |
| A Clinical Trial Testing the Safety of Pumitamig (an Investigational Drug) and How Well it Works When Combined With Chemotherapy for People Who Have Not Been Treated Yet for Pancreatic Cancer (NCT07255404) | BioNTech SE | 2025-12-04 |
| A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014) (NCT07209111) | Merck Sharp & Dohme LLC | 2025-12-04 |
| Improving Physical Ability and Cellular Senescence Elimination in HIV (NCT07144293) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-12-04 |
| Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer (NCT06961084) | Thomas Hope | 2025-12-04 |
| RVU120 Rollover Study (NCT06987058) | Ryvu Therapeutics SA | 2025-12-04 |
| A Study Assessing Safety, Tolerability, and Efficacy of INNA-051 in Preventing Respiratory Illness Due to Viral Infections in Healthy Adults 18 to 45 Years of Age (NCT07222670) | ENA Respiratory Pty Ltd | 2025-12-04 |
| A Study to Evaluate Safety and Efficacy of OLX72021 in Healthy Males With Androgenetic Alopecia (NCT07327359) | Olix Pharmaceuticals, Inc. | 2025-12-04 |
| A Trial of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NCT07232849) | Jiangsu HengRui Medicine Co., Ltd. | 2025-12-04 |
| Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN) (NCT06980948) | Sangamo Therapeutics | 2025-12-04 |
| Orexin Receptor Antagonism for the Treatment of Alcohol Use Disorder and Stress-Related Drinking (NCT07214207) | Ohio State University | 2025-12-04 |
| Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin (NCT07283835) | Lepu Biopharma Co., Ltd. | 2025-12-04 |
| A Study of Pembrolizumab in People With Ultra-Rare Sarcomas (NCT07089992) | Memorial Sloan Kettering Cancer Center | 2025-12-04 |
| Evaluation of the Safety and Efficacy of LB-DTK-MV in Patients Diagnosed With Antiviral-Resistant CMV, BKV, or EBV Infection or Associated Diseases Following Anticancer Therapy or Allogeneic Hematopoietic Stem Cell Transplantation. (NCT07670468) | LucasBio | 2025-12-04 |
| Immunogenicity of RSVPreF3 Vaccine in Immunocompromised Persons (NCT07050732) | Johns Hopkins University | 2025-12-04 |
| Clinical Trial of VBC103 in Patients With Advanced Malignant Solid Tumors (NCT07299747) | VelaVigo Bio Inc | 2025-12-04 |
| An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors (NCT07371663) | Beijing Tide Pharmaceutical Co., Ltd | 2025-12-03 |
| Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients (NCT07116746) | Arthrosi Therapeutics | 2025-12-03 |
| New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia (NCT06944145) | Beth Israel Deaconess Medical Center | 2025-12-03 |
| A Study to Evaluate AI-09 In Participants With Glabellar Lines (NCT07321834) | Eirion Therapeutics Inc. | 2025-12-03 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus (NCT07260877) | Ventus Therapeutics U.S., Inc. | 2025-12-03 |
| Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression (NCT06419439) | VA Office of Research and Development | 2025-12-03 |
| A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS) (NCT07268638) | Akebia Therapeutics | 2025-12-03 |
| Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis. (NCT06902805) | Assistance Publique - Hôpitaux de Paris | 2025-12-03 |
| A Phase 2A Trial of DT402 for Autism Spectrum Disorder (NCT07303907) | Definium Therapeutics US, Inc. | 2025-12-03 |
| Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma (NCT06991101) | Baptist Health South Florida | 2025-12-03 |
| Serplulimab for Locally Advanced Cervical Cancer (NCT07340489) | Tianjin Medical University Cancer Institute and Hospital | 2025-12-03 |
| Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma (NCT06961357) | H. Lee Moffitt Cancer Center and Research Institute | 2025-12-03 |
| Study of ABS-201 Evaluating Single and Multiple Ascending Doses in Healthy Adults With and Without Androgenetic Alopecia (NCT07317544) | Absci Pty Ltd. | 2025-12-03 |
| Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis (NCT07290569) | Oruka Therapeutics, Inc. | 2025-12-03 |
| A Phase I/II Clinical Study of SHR-4298 Injection in Patients With Malignant Solid Tumors (NCT07229612) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-12-03 |
| Amping up With PemJAK (NCT07283822) | Seda S. Tolu | 2025-12-03 |
| First-Line Jaktinib for Acute Graft-Versus-Host Disease (aGVHD) (NCT07285889) | First Affiliated Hospital of Zhejiang University | 2025-12-03 |
| Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for Gastric Cancer at High Risk of Peritoneal Recurrence (NCT07139951) | Mayo Clinic | 2025-12-03 |
| A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1 (NCT07292168) | Kidney Cancer Research Bureau | 2025-12-02 |
| Cutting Edge Imaging With PET-FAPI for Earlier Pancreatic Cancer Diagnosis (INDIGO-FAPI) (NCT06659705) | Institut Curie | 2025-12-02 |
| Effects of NLS-133, a Potential Non-Hormonal "On-Demand" Male Contraceptive (NCT07393334) | Next Life Sciences | 2025-12-02 |
| A Study of LBL-024 in Combination With Paclitaxel ± Bevacizumab for the Treatment of Platinum-resistant Ovarian Cancer (NCT07042802) | Nanjing Leads Biolabs Co.,Ltd | 2025-12-02 |
| A Study of DII235 in Adults With Elevated Lipoprotein(a) (NCT07235046) | Novartis Pharmaceuticals | 2025-12-02 |
| Phase II Trial of Amivantamab Plus Monochemotherapy in Platinum Unfit NSCLC Patients With EGFR exon20 Insertion Mutations. (NCT07392658) | Fondazione Ricerca Traslazionale | 2025-12-02 |
| Study of ZG005 in Combination With Platinum-Based Chemotherapy in Participants With Advanced Biliary Tract Carcinoma (NCT07099547) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2025-12-02 |
| SGLT2 Inhibitors in Geographic Atrophy (NCT07174687) | Washington University School of Medicine | 2025-12-02 |
| Study to Evaluate HM15275 in Obese or Overweight Subjects Without Diabetes Mellitus (NCT07205900) | Hanmi Pharmaceutical Company Limited | 2025-12-02 |
| A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK) (NCT07116031) | Sanofi | 2025-12-02 |
| Linvoseltamab in Addition to Lenalidomide (L2) During Maintenance Therapy of NDMM to Deepen Responses or Redrive MRD Negativity After Relapse (NCT06910124) | Dickran Kazandjian, MD | 2025-12-02 |
| Impact of Circadian Rhythm on Immunotherapy (NCT07224971) | Liza Villaruz, MD | 2025-12-02 |
| A Study of SHR-7367 With Anti-tumor Agents in Patients With Solid Tumors (NCT07229586) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2025-12-02 |
| Midazolam Adjunct Therapy for Prevention of PONV in Gynecological Laparoscopy (NCT07668700) | Hameed Latif Hospital, Lahore | 2025-12-02 |
| Hypertonic Saline in Posterior Spinal Fusion (NCT06822374) | Joseph D. Tobias | 2025-12-01 |
| Formoterol in Diabetes (NCT07022418) | Medical University of South Carolina | 2025-12-01 |
| Immune Cell Therapy for Advanced Solid Tumors (NCT07260058) | Liaoning Medical Diagnosis and Treatment Technology Research and Development Co., Ltd. | 2025-12-01 |
| PPV-06 Vaccine in Inflammatory Knee Osteoarthritis (NCT06605963) | Peptinov SAS | 2025-12-01 |
| Phase IIa Study of BRY812 Monotherapy in Advanced Gynecological Malignancies (NCT07311538) | BioRay Pharmaceutical Co., Ltd. | 2025-12-01 |
| A Long-term Safety and Efficacy Study Evaluating CM512 in Atopic Dermatitis. (NCT07230483) | Keymed Biosciences Co.Ltd | 2025-12-01 |
| Repeated Mesenchymal Stem Cell Therapy for Radiation-Induced Hyposalivation and Xerostomia in Head and Neck Cancer Survivors (NCT07290946) | Christian von Buchwald | 2025-12-01 |
| SCRT(Short Course Radiotherapy) Combined With CAPOX Plus QL1706 for Rectal Cancer Liver Metastases (NCT06787183) | Fujian Cancer Hospital | 2025-12-01 |
| Castration With Abiraterone 250 mg Without LHRH Analogs or Blockers in Patients With Prostate Cancer Requiring Hormonal Intensification (Multicenter Phase 2) (NCT07299292) | SMED Clinical Research | 2025-12-01 |
| Safety and Preliminary Effectiveness Study of Mesenchymal Stem Cells, HeXell-2020, in Patients With Stable Coronary Artery Disease (NCT07137104) | Hexun Biosciences Co., LTD. | 2025-12-01 |
| PRaG-1 Plus PRaG Therapy in Advanced Solid Tumors: A Prospective Clinical Trial (PRaG 10.0) (NCT07267234) | Second Affiliated Hospital of Soochow University | 2025-12-01 |
| Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations (NCT07188142) | Beenish Hassan | 2025-12-01 |
| First-Line Sacituzumab Govitecan in Advanced Untreated Triple-Negative Breast Cancer Patients. (NCT07299409) | Nathalie Levasseur | 2025-12-01 |
| A Phase Ⅰ/Ⅱa Study of SNUG01 in Adult Subjects With ALS (NCT07169175) | SineuGene Therapeutics Co., Ltd. | 2025-12-01 |
| A Single-arm Clinical Study Evaluating Pirfenidone and Sintilimab in Combination With Standard Neoadjuvant Chemotherapy for Colorectal Cancer Patients With Peritoneal Metastasis. (NCT07268677) | Guoxiang Cai | 2025-12-01 |
| Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer (NCT07146646) | Case Comprehensive Cancer Center | 2025-12-01 |
| Aleniglipron Phase 2 in Type 2 Diabetes Mellitus (NCT07400588) | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics | 2025-12-01 |
| Immunotherapy With N 803, ETBX-071, and M-CENK in Combination With Radiation for Participants With High-Risk Prostate Cancer. (NCT06765954) | ImmunityBio, Inc. | 2025-12-01 |
| Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder Cancer (NCT07261592) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2025-12-01 |
| A Study of SHR-A1811 Combined With Adebelimumab as Neoadjuvant Therapy for Resectable HER2-Altered Non-Small Cell Lung Cancer (NCT07281209) | Shanghai Chest Hospital | 2025-12-01 |
| Combination Immunotherapy for the Treatment of Chemotherapy-refractory Metastatic MSS CRC (NCT07281716) | Dan Feng | 2025-12-01 |
| Alendronate to Reduce Pelvic Insufficiency Fractures in Cervical Cancer Patients Undergoing Chemoradiation (NCT07245381) | Dr. Itay GoorAryeh | 2025-12-01 |
| A Multicenter Phase 2 Single-arm Proof-of-concept Trial Assessing the Efficacy and Safety of Obinutuzumab in the Treatment of Non-infectious Active Cryoglobulinemia Vasculitis Refractory or Intolerant to Rituximab (NCT07268521) | Assistance Publique - Hôpitaux de Paris | 2025-12-01 |
| Nano-crystalline Megestrol Acetate for Chemotherapy-induced Nausea and Vomiting (NCT07246070) | AIPING ZHOU | 2025-12-01 |
| A Dose Regimen Study of BRM421 Ophthalmic Solution in Patients With Dry Eye Disease (NCT07078955) | BRIM Biotechnology Inc. | 2025-12-01 |