| Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer (NCT07250477) | University of California, Davis | 2026-01-30 |
| Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study (NCT07266025) | Shanghai Zhongshan Hospital | 2026-01-30 |
| Pharmacokinetics, Efficacy, and Safety of Encaleret in Pediatric Participants With Autosomal Dominant Hypocalcemia Type 1 (ADH1) (NCT07080385) | Calcilytix Therapeutics, Inc., a BridgeBio company | 2026-01-30 |
| A Phase 1b/2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Combination With Low Intensity Chemotherapy in Older Patients With Newly Diagnosed B-Cell Acute Lymphoblastic Leukemia (NCT07153796) | M.D. Anderson Cancer Center | 2026-01-30 |
| Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism (NCT07091279) | Jeremy Veenstra-vanderweele | 2026-01-30 |
| Drug Sensitivity Testing-Based Tumor Organoids to Guide Adjuvant Therapy After Hepatectomy for Primary Liver Cancer (NCT07363356) | Eastern Hepatobiliary Surgery Hospital | 2026-01-30 |
| A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Hepatocellular Carcinoma (NCT07351513) | Eastern Hepatobiliary Surgery Hospital | 2026-01-30 |
| SKB500 Combinations in Patients With Small Cell Lung Cancer (NCT07296809) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2026-01-30 |
| A Clinical Trial Evaluating the Safety of TD001 In Patients With PSMA-Expressing Metastatic Prostate Cancer (NCT07258407) | T.O.A.D. Oncology SA | 2026-01-30 |
| A Phase 2 Randomized, Controlled Trial of QL1706 Plus Chemotherapy and Quad Shot for Driver Gene-negative Advanced Non-small Cell Lung Cancer. (NCT07271602) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2026-01-30 |
| Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease (NCT06875128) | Delcath Systems Inc. | 2026-01-29 |
| Exploratory Study of LP-98 for Injection in ART-Naive HIV-Infected Individuals (NCT07433387) | Shanxi Kangbao Biological Product Co., Ltd. | 2026-01-29 |
| Fulzerasib Sequential Sintilimab Plus Platinum-Doublet Neoadjuvant Therapy for Resectable KRAS G12C-Mutant NSCLC (NCT07492342) | Jianxing He | 2026-01-29 |
| Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder (NCT06651177) | T. John Winhusen, PhD | 2026-01-29 |
| Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Surgery in Stage III NSCLC (NCT06878274) | Centre hospitalier de l'Université de Montréal (CHUM) | 2026-01-29 |
| SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy. (NCT06614322) | University of Rochester | 2026-01-29 |
| A Phase 1/2 Study of GW5282 in Participants With Advanced Solid Tumors (NCT07328217) | Dizal Pharmaceuticals | 2026-01-29 |
| Low-Tech Treatments for Obstructive Sleep Apnea (NCT07301710) | Uniformed Services University of the Health Sciences | 2026-01-29 |
| Safety of Antithrombotic Heparin Proteoglycan Mimetic APAC in Peripheral Arterial Occlusive Disease and Chronic Limb-threatening Ischemia (NCT07352800) | Aplagon Oy | 2026-01-29 |
| A Study of MR001 in Patients With Locally Recurrent or Metastatic Advanced Triple-Negative Breast Cancer (TNBC) (NCT07208149) | Shenzhen Majory Biotechnology Co., Ltd. | 2026-01-29 |
| A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003) (NCT07227597) | Merck Sharp & Dohme LLC | 2026-01-29 |
| A Clinical Study of Sintilimab Combined With Chemothrapy Versus Chemotherapy as Adjuvant Therapy for Gastric/Gastroesophageal Junction Adenocarcinoma (NCT07492615) | Fudan University | 2026-01-29 |
| A Phase II Clinical Trial to Evaluate the Efficacy and Safety of FXS5626 in Patients With NIU (NCT07552012) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2026-01-29 |
| A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP (NCT07024316) | Atlas Molecular Pharma | 2026-01-29 |
| Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease (NCT07439887) | Ray Therapeutics, Inc. | 2026-01-28 |
| Rituximab Combining Anti-CD38 Monoclonal Antibody Versus Rituximab in the Management of Primary Immune Thrombocytopenia (ITP) (NCT07234019) | Institute of Hematology & Blood Diseases Hospital, China | 2026-01-28 |
| Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia (NCT07278557) | UNC Lineberger Comprehensive Cancer Center | 2026-01-28 |
| Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma (NCT07225621) | Alpheus Medical, Inc. | 2026-01-28 |
| A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma (NCT07323654) | Kymera Therapeutics, Inc. | 2026-01-28 |
| A Phase I/II, Dose-finding Study to Assess the Safety, Reactogenicity, and Immunogenicity of a Broadly Protective Sarbecovirus Vaccine (GBP511) in Healthy Adults. (NCT07280858) | SK Bioscience Co., Ltd. | 2026-01-28 |
| A Single-arm, Phase II, Multi-center Clinical Trial of Sintilimab During the Perioperative Period in Patients With Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma (NCT07379424) | chen chao Professor | 2026-01-28 |
| A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC (NCT07385001) | Tang-Du Hospital | 2026-01-28 |
| A Phase II Study of HRS-4642 Combined With AG (Nab-paclitaxel and Gemcitabine) as Conversion Therapy for Locally Advanced Pancreatic Cancer (NCT07438106) | The First Affiliated Hospital with Nanjing Medical University | 2026-01-28 |
| Neoadjuvant Chemoimmunotherapy or Chemoradiotherapy in ESCC (NCT07385664) | Ji Yongling | 2026-01-28 |
| SKB264 Plus QL1706 in Recurrent or Metastatic Cervical Cancer (NCT07256236) | Fujian Cancer Hospital | 2026-01-28 |
| A Study of the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone in People With Acute Myeloid Leukemia (NCT07392242) | Memorial Sloan Kettering Cancer Center | 2026-01-27 |
| Fisetin in Mild Alzheimer's Disease (NCT07279714) | Sunnybrook Health Sciences Centre | 2026-01-27 |
| LSD Treatment for Persons With Alcohol Use Disorder (NCT05474989) | Felix Mueller | 2026-01-27 |
| Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial (NCT07060638) | Samer Gawrieh | 2026-01-27 |
| A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs (NCT07336446) | AstraZeneca | 2026-01-27 |
| A Trial of LBL-024 Monotherapy or Combination Drug in Patients With Triple Negative Breast Cancer (NCT07281976) | Nanjing Leads Biolabs Co.,Ltd | 2026-01-27 |
| Intestinal Microbiome Transplant in ALS (NCT07017946) | Duke University | 2026-01-27 |
| A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement (NCT06728410) | Mehmet Akce | 2026-01-27 |
| A Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX87in Combination With HLX22 or Pertuzumab in the Neoadjuvant Therapy of HER2-Positive Bresat Cancer (NCT07294534) | Shanghai Henlius Biotech | 2026-01-27 |
| Effect of Postbiotics on Microbiota and Systemic Immunomodulation of Pembrolizumab as First-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (RM HNSCC) (NCT07485296) | Gruppo Oncologico del Nord-Ovest | 2026-01-27 |
| Relacorilant With Nab-Paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma (NCT07259317) | Corcept Therapeutics | 2026-01-27 |
| Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer (NCT07042685) | The Methodist Hospital Research Institute | 2026-01-27 |
| Injection Sclerotherapy With Bleomycin VS Doxycycline in Patients With Lymphatic Malformations (NCT07320001) | Basharat Hussain | 2026-01-26 |
| A Study of Zasocitinib in Adults With Hidradenitis Suppurativa (NCT07244263) | Takeda | 2026-01-26 |
| Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma. (NCT07173972) | Oslo University Hospital | 2026-01-26 |
| Desloratadine in Patients With Ulcerative Colitis (NCT07333716) | Tanta University | 2026-01-26 |
| Evaluation of CT-XPI (NCT07192133) | University of Wisconsin, Madison | 2026-01-26 |
| Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma (NCT07169344) | Oslo University Hospital | 2026-01-26 |
| A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD) (NCT07286006) | Immunovant Sciences GmbH | 2026-01-26 |
| Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors (NCT07287917) | Aminex Therapeutics, Inc. | 2026-01-26 |
| Phase II Trial of PRT-064040 Nasal Spray for the Treatment of Migraine in Adults (NCT07304518) | Sichuan Purity Pharmaceutical Technology Co., Ltd. | 2026-01-26 |
| Gilteritinib Plus VA Followed By Consolidation Chemotherapy in Newly Diagnosed FLT3-ITD+ AML (NCT07259707) | First Affiliated Hospital of Zhejiang University | 2026-01-25 |
| Golidocitinib Combined With P-GemOx Plus PD-1 Inhibitor Versus P-GemOx Plus PD-1 Inhibitor in First-Line Newly Diagnosed Advanced or Non-Nasal Extranodal NK/T-Cell Lymphoma (NCT07385989) | WEI XU | 2026-01-25 |
| Refining Fertility-sparing Treatment in Endometrial Carcinoma Based on Molecular Classification (NCT07319429) | Fudan University | 2026-01-25 |
| Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line Induction (NCT07376499) | China Medical University, China | 2026-01-25 |
| Topical Application of Lactobacillus Reuteri for Androgenetic Alopecia (NCT07370519) | Shenzhen People's Hospital | 2026-01-25 |
| Toripalimab Plus Bevacizumab Combined Three Intra-arterial Therapies (TACE, HAIC, or TACE-HAIC) for Unresectable Hepatocellular Carcinoma: a Phase 2, Multicenter Randomised Non-comparative Trial (NCT07380633) | Sun Yat-sen University | 2026-01-23 |
| Stratified Pharmacological Approaches for Regulating Circuit-Level Effects (NCT07022405) | Stanford University | 2026-01-23 |
| REGULUS: MRI-guided Adaptive SABR for Liver Cancers (NCT07223307) | Stanford University | 2026-01-23 |
| A Phase II Clinical Study Evaluating the Combination Therapy of JS212 in Patients With Advanced Lung Cancer (NCT07309276) | Shanghai Junshi Bioscience Co., Ltd. | 2026-01-23 |
| Pilot Study of RR-HNK in OCD (NCT06575075) | Carolyn Rodriguez | 2026-01-23 |
| Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy (NCT07201519) | Michael J Cavnar, MD | 2026-01-23 |
| Pembrolizumab Maintenance After Enfortumab Vedotin (EV)/Pembro Induction in Front-Line Metastatic Urothelial Carcinoma (NCT07221942) | Fox Chase Cancer Center | 2026-01-23 |
| Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE. (NCT07494305) | LB Pharmaceuticals Inc. | 2026-01-23 |
| Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis (NCT07230288) | AbbVie | 2026-01-23 |
| Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients (NCT07303296) | GenSight Biologics | 2026-01-22 |
| Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma (NCT07096778) | CellCentric Ltd. | 2026-01-22 |
| Safety of Atezolizumab-Bevacizumab in Liver Transplanted Patients With Advanced Hepatocellular Carcinoma (NCT06254248) | Assistance Publique - Hôpitaux de Paris | 2026-01-22 |
| Rifaximin Versus No Intervention for the Treatment of IgG/IgA (Non-IgM) Monoclonal Gammopathy of Undetermined Significance (NCT07209371) | Fred Hutchinson Cancer Center | 2026-01-22 |
| Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis (NCT07332091) | CSL Behring | 2026-01-22 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus (NCT07321678) | Ascletis Pharma (China) Co., Limited | 2026-01-22 |
| A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH) (NCT07159841) | Crinetics Pharmaceuticals Inc. | 2026-01-22 |
| A Study of Isoquercetin in People With Ovarian Cancer (NCT07303894) | Memorial Sloan Kettering Cancer Center | 2026-01-22 |
| Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial (NCT07158021) | University of Michigan Rogel Cancer Center | 2026-01-22 |
| Painful Post-Operative Hip Study (NCT07066709) | University of Wisconsin, Madison | 2026-01-21 |
| Neo-adjuvant Immunotherapy Master Trial for Localized Cancers (NCT07262489) | UNICANCER | 2026-01-21 |
| Efficacy and Safety of Dalpiciclib Combined With Endocrine Adjuvant Therapy for Early HR +/HER2- Breast Cancer: a Multicenter, Prospective Clinical Study (NCT07581834) | Fujian Cancer Hospital | 2026-01-21 |
| Telmisartan in Combination With Cytotoxic Regimens in Platinum-Resistant Ovarian Cancer (NCT06815497) | Tyler J Curiel | 2026-01-21 |
| Methotrexate for Severe Vulvar Lichen Sclerosus (NCT07352917) | Clinica Dermatologica Arbache ltda | 2026-01-21 |
| Safety and Efficacy of T10430 Eye Drops in Controlling Paediatric Myopia Progression (NCT07522242) | Laboratoires Thea | 2026-01-21 |
| Phase Ib/II Study of QL1706 + Fruquintinib + SCRT vs. Standard Third-Line Therapy in Unresectable Liver-Metastatic pMMR/MSS Colorectal Cancer: Safety, Tolerability, and Efficacy. (NCT07353268) | Tao Zhang | 2026-01-21 |
| Tenecteplase Plus Urinary Kallidinogenase for Acute Ischemic Stroke (TUKIS) (NCT07283159) | General Hospital of Shenyang Military Region | 2026-01-20 |
| A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC (NCT07269782) | Shanghai Henlius Biotech | 2026-01-20 |
| Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus (NCT07282743) | Sun Pharmaceutical Industries Limited | 2026-01-20 |
| Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE) (NCT06041503) | National Cancer Institute (NCI) | 2026-01-20 |
| D-SPARK: A Clinical Trial of D-Serine for Modifying Parkinson's Disease Progression (NCT07312110) | Haukeland University Hospital | 2026-01-20 |
| Safety and Efficacy of Imatinib in Combination With Artemether-Lumefantrine for Uncomplicated Malaria (NCT07559370) | Victoria Biomedical Research Institute | 2026-01-20 |
| A Study to Evaluate the Efficacy and Safety of LP-003 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) (NCT07313917) | Longbio Pharma | 2026-01-20 |
| Pentoxifylline in Patients With Ulcerative Colitis (NCT07349472) | Ihab Elsayed Hassan | 2026-01-20 |
| A Single-Arm Phase Ⅱ Study of Fluzoparib Maintenance in Platinum-sensitive Advanced Triple-Negative Breast Cance (NCT07321015) | Tianjin Medical University Cancer Institute and Hospital | 2026-01-20 |
| EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors (NCT07262619) | Eikon Therapeutics | 2026-01-20 |
| Epirubicin Interventional Chemotherapy for Sinonasal Adenoid Cystic Carcinoma (SNACC): A Prospective Study (NCT07320508) | Eye & ENT Hospital of Fudan University | 2026-01-20 |
| A Multicohort Study of Toripalimab in Combination With Investigator-Selected Chemotherapy for Advanced HER2-Negative Breast Cancer (NCT07540533) | Henan Cancer Hospital | 2026-01-20 |
| A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis (NCT07230860) | Janssen Research & Development, LLC | 2026-01-20 |
| A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell Transplant (NCT07359859) | Memorial Sloan Kettering Cancer Center | 2026-01-20 |