| Intrathecal Amniotic Fluid Stem Cells for Progressive Multiple Sclerosis (NCT06841068) | Wake Forest University Health Sciences | 2026-02-01 |
| A Phase 1/2 Study of T-cell Expressing an Anti-CD22 Chimeric-Antigen Receptor (SHB-04-CD22) in Patients With CD22-expressing B-cell Malignancies (NCT07135466) | Sheba Medical Center | 2026-02-01 |
| FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma (NCT07353827) | Sun Yat-sen University | 2026-02-01 |
| Venetoclax Combined With Azacitidine for Consolidation Therapy in AML (NCT07425782) | The First Affiliated Hospital of Soochow University | 2026-02-01 |
| Ripertamab for the Treatment of Myasthenia Gravis (NCT07372807) | Zhongming Qiu | 2026-02-01 |
| A Single-arm, Single-center, Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Bevacizumab and Standard Chemotherapy as First-line Treatment for MSS/pMMR Metastatic Colorectal Cancer With BRAF V600E Mutation (NCT07229846) | Yanqiao Zhang | 2026-02-01 |
| Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study) (NCT07381400) | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 2026-02-01 |
| Gossypol Acetate + FOLFIRI + Bev in mCRC With TP53-Mutant and LRPPRC Positive (NCT07337551) | Guiying Wang | 2026-02-01 |
| A Study of Bemotuzumab Plus Chemotherapy and Anlotinib Induction Followed by Bemotuzumab, Anlotinib and Consolidative Thoracic Radiotherapy in Extensive-Stage Small Cell Lung Cancer (NCT07358676) | Tianjin Medical University Cancer Institute and Hospital | 2026-02-01 |
| A Phase 2, Single Arm Multicenter, Study Testing Mezigdomide, Carfilzomib, and Dexamethasone (480Kd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (NCT07348393) | Assistance Publique - Hôpitaux de Paris | 2026-02-01 |
| Response-Based Local Therapy for Regionally Advanced Breast Cancer (NCT07376538) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-02-01 |
| IBI343 Combined With Chemotherapy as Neoadjuvant Therapy in Borderline Resectable Pancreatic Cancer (NCT07415525) | Zhejiang University | 2026-02-01 |
| Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma (NCT07448415) | Assiut University | 2026-02-01 |
| Early Inflammatory-Immune Stratification and Precision Glucocorticoid Intervention in Acute Respiratory Failure Induced by Community-Acquired Pneumonia (NCT07357935) | Qingyuan Zhan | 2026-02-01 |
| Effects of Probiotics on Respiratory Tract Infections in Children: A Randomized, Placebo-Controlled Interventional Study (NCT07498127) | Min-Tze LIONG | 2026-02-01 |
| Clinical Trial Evaluating Safety and Efficacy of Resomelagon on Dengue Infection (RESOVIR-2) (NCT06917001) | Federal University of Minas Gerais | 2026-02-01 |
| Probiotic Supplementation in Optimizing Iron and Hematological Status Among Pregnant Females (NCT07076849) | University of Illinois at Chicago | 2026-02-01 |
| A Phase II Study of Neoadjuvant Sacituzumab Tirumotecan in Combination With Iparomlimab and Tuvonralimab in Locally Advanced Cervical Cancer (NCT07348861) | Zheng Min | 2026-02-01 |
| Safety and Tolerability of IDO-1 Inhibition in the Prevention of EBV-related Pathology in EBV Negative Kidney Transplant Recipients Receiving an Organ From EBV Positive Donors (NCT07368153) | University Hospital, Basel, Switzerland | 2026-02-01 |
| Serious Game to Teach Opioid Overdose Response (NCT06727786) | University of Nevada, Reno | 2026-02-01 |
| Evaluating Safe Ketone Thresholds To Minimise Ketosis in People With Type 1 Diabetes Using Dapagliflozin (NCT07225465) | St Vincent's Hospital Melbourne | 2026-02-01 |
| A Phase II Study of Utidelone With Toripalimab in Advanced Cervical Cancer (NCT07363330) | Zhongnan Hospital | 2026-02-01 |
| A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer (NCT07527026) | Chinese PLA General Hospital | 2026-02-01 |
| Swedish Cardiac And Renal Failure Study-1 (NCT07029503) | Karolinska Institutet | 2026-02-01 |
| FAD Subtype-Guided Combination Therapy for Unresectable Hepatocellular Carcinoma (NCT07314372) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2026-02-01 |
| CAPOX and Bevacizumab With or Without Primary Tumor Radiotherapy and Iparomlimab and Tuvonralimab as First-line Treatment for RAS-Mutant/MSS Metastatic Rectal Cancer (NCT07383285) | Peking University Cancer Hospital & Institute | 2026-02-01 |
| A Study of Bosmolisib (BR101801) in Participants With R/R PTCL. (NCT07180771) | Boryung Pharmaceutical Co., Ltd | 2026-02-01 |
| A Prospective, Multicenter, Open-label, Single-arm Phase II Clinical Study Evaluating the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With the PraG Strategy for the Treatment of Soft Tissue Sarcoma (NCT07342322) | First Affiliated Hospital of Guangxi Medical University | 2026-02-01 |
| Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus (NCT07364396) | Curocell Inc. | 2026-02-01 |
| FMT in Triple Negative Breast Cancer Guided by ctDNA (NCT07292142) | Jewish General Hospital | 2026-02-01 |
| Scipibaimab Combined With Tislelizumab in Patients With First-Line Treatment-Failed Recurrent/Metastatic Nasopharyngeal Carcinoma (NCT07388758) | Sun Yat-sen University | 2026-02-01 |
| Phase II Prospective Cohort Study of Intravesical Recombinant Human Type 5 Adenovirus Injection for Treatment of High-Risk Non-Muscle Invasive Bladder Cancer: Evaluating Efficacy and Safety (NCT07356791) | RenJi Hospital | 2026-02-01 |
| Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Patients (NCT06953791) | University Hospital Tuebingen | 2026-02-01 |
| NECTAR Study: Neoadjuvant Toripalimab + 9MW2821 for Local UTUC (NCT07412171) | Peking University Third Hospital | 2026-02-01 |
| Zimberelimab + Domvanalimab in Gastroesophageal Adenocarcinoma (NCT07283848) | Massachusetts General Hospital | 2026-02-01 |
| Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones (NCT07408076) | University of California, Los Angeles | 2026-02-01 |
| Neoadjuvant Embolization and Cytoreduction in Prostate Cancer (NCT07251829) | Srinivas Raman | 2026-02-01 |
| Melatonin for Glycemic Control in Gestational Diabetes Mellitus (NCT07369284) | Obstetrics & Gynecology Hospital of Fudan University | 2026-02-01 |
| Kamlanoflast In Amyotrophic Lateral Sclerosis (NCT07396818) | Inflammasome Therapeutics | 2026-02-01 |
| Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain (NCT07399860) | Lomonosov Moscow State University Medical Research and Educational Center | 2026-02-01 |
| Dual-Target CAR-NK Cells for Biomarker-Selected Advanced Colorectal Cancer (NCT07462650) | Beijing Biotech | 2026-02-01 |
| Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer (NCT07394192) | Peking University Cancer Hospital & Institute | 2026-02-01 |
| A Multicenter Single-arm Prospective Clinical Study on First-line Treatment of Pancreatic Cancer Liver Metastases With Arterial Infusion Chemotherapy and Embolization Combined With Dual Immune Checkpoint Inhibitors. (NCT07333287) | Shandong Provincial Hospital | 2026-02-01 |
| Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 Trial (NCT07370987) | Assistance Publique - Hôpitaux de Paris | 2026-02-01 |
| Implementation of an Advanced Telerehabilitation Solution for People With Multiple Sclerosis (NCT07310914) | Danish Multiple Sclerosis Hospitals | 2026-02-01 |
| Inhibition of Late Sodium Current (INa) to Prevent Coronary MICROvascular Dysfunction in Patients Presenting With ST-Elevation Myocardial Infarction and Multivessel Disease: INaMICRON Study (NCT07380919) | Federico II University | 2026-02-01 |
| Add-on Diuretics in Acute Decompensated Heart Failure (NCT07372040) | Tanta University | 2026-02-01 |
| Clinical Observation of Bupivacaine Liposome for Lower Extremity Nerve Block (NCT07366905) | Hainan Medical College | 2026-02-01 |
| Golidocitinib for Refractory Immune-related Hematologic Toxicities of Advanced Lung Cancer (NCT07303881) | The First Affiliated Hospital of Guangzhou Medical University | 2026-02-01 |
| YN001-004 in Patients With Coronary Atherosclerosis in Australia (NCT06700720) | Beijing Inno Medicine Co., Ltd. | 2026-02-01 |
| Focal Versus Whole Gland High Dose-Rate Brachytherapy (HDR-BT) Boost to External Beam Radiotherapy in Localized Prostate Cancer: A Phase 2 Randomized Trial (NCT07300566) | Joelle Helou | 2026-02-01 |
| Study Assessing Reduced HPV Infectivity and Transmission in HPV-Positive Women Following Vaccination With 9vHPV (NCT07303751) | Institut d'Investigació Biomèdica de Bellvitge | 2026-02-01 |
| The AminoECMO Pilot Trial (NCT07438262) | Australian and New Zealand Intensive Care Research Centre | 2026-02-01 |
| Neoadjuvant Becotatug Vedotin Plus Pucotenlimab and Cisplatin for Locally Advanced Head and Neck Squamous Cell Carcinoma (NCT07393477) | Sir Run Run Shaw Hospital | 2026-02-01 |
| A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders (NCT04454684) | Resilient Pharmaceuticals | 2026-02-01 |
| Neoadjuvant Immunotherapy ± Radiotherapy in MSI-H/dMMR Locally Advanced Colorectal Cancer (NCT07403877) | Fudan University | 2026-02-01 |
| First-Line Lenvatinib in Child-Pugh B Patients With HCC Unsuitable for Curative Treatment (NCT07297654) | National Cancer Center, Korea | 2026-02-01 |
| Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia (NCT07387900) | Cairo University | 2026-02-01 |
| A Study to Evaluate the Efficacy and Safety of Inavolisib When Administered in Combination With Bevacizumab and FOLFOX or FOLFIRI as First Line Therapy in Participants With Colorectal Cancer (NCT07323576) | Hoffmann-La Roche | 2026-02-01 |
| SEED-CRYO: Sequential 125I Seed Implantation Followed by Cryoablation vs Single-Modality Local Therapy in Unresectable Solid Tumors (NCT07450352) | Li Min | 2026-02-01 |
| Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD (NCT07441395) | Corvus Pharmaceuticals, Inc. | 2026-02-01 |
| MRG003 Combined With Immunotherapy in Recurrent/Metastatic Nasopharyngeal Carcinoma: A Phase II Clinical Trial (NCT07381699) | West China Hospital | 2026-02-01 |
| Comparison of Hypotension After Spinal Anesthesia With Hyperbaric Vs Isobaric Bupivacaine in Elective Cesarean After Colloid Preloading. (NCT07416084) | Liaquat National Hospital & Medical College | 2026-02-01 |
| Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer (NCT07290621) | University of Chicago | 2026-02-01 |
| Neoadjuvant Therapy Combined With Trastuzumab Rezetecan and Toripalimab for HR+/HER2-low Breast Cancer (NEOTORCH-BREAST 08) (NCT07383818) | First Affiliated Hospital of Zhejiang University | 2026-02-01 |
| Beta-sitosterol for Subarachnoid Hemorrhage: Mechanistic Analysis of Recovery and Therapy (NCT07457333) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-02-01 |
| Iparomlimab and Tuvonralimab Injection Combined With GemOX and Lenvatinib as Conversion Therapy for Initially Potentially Resectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer (NCT07263360) | Tianjin Medical University Cancer Institute and Hospital | 2026-02-01 |
| PHOENIX: QL1706 Plus Chemotherapy and Bevacizumab in AGA-Resistant, PD-L1 ≥50% Non-Squamous NSCLC (NCT07416058) | Guangdong Association of Clinical Trials | 2026-01-31 |
| Efficacy and Safety of Hyperbaric Oxygen Therapy in Improving Nab-paclitaxel-Induced Peripheral Neuropathy (NCT07410169) | Guangdong Provincial People's Hospital | 2026-01-31 |
| XELOX Plus DoSTARlimab Versus XELOX Alone as Consolidation Treatment After Standard Chemoradiation in pMMR/MSS or MSI-Low Locally Advanced Rectal Cancer (LARC) Patients (NCT07381777) | Gruppo Oncologico Italiano di Ricerca Clinica | 2026-01-31 |
| Study of MCLA-129 in Combination With Ensartinib in Patients With Advanced Solid Tumors. (NCT07448116) | Betta Pharmaceuticals Co., Ltd. | 2026-01-31 |
| A Study of Hetrombopag Combined With rhTPO in the Treatment of Cancer Therapy-induced Thrombocytopenia (CTIT) in Solid Tumor Patients. (NCT07334093) | Sun Yat-sen University | 2026-01-31 |
| Safety and Efficacy of Human Adipose-Derived Stem Cell Exosomes in Acute Ischemic Stroke (NCT07398612) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2026-01-31 |
| Factors Influencing Immunotherapy Response in dMMR/MSI-H Gastric/Gastroesophageal Junction Adenocarcinoma (NCT07259473) | Shanghai Zhongshan Hospital | 2026-01-31 |
| Clinical Study of Anti-CLL1-CD33-NKG2D Bicephali CAR-T for Relapsed/Refractory Acute Myeloid Leukemia (NCT07370064) | Xuzhou Medical University | 2026-01-31 |
| Phase IIa Clinical Trial of YN001 in Patients With Atherosclerotic Cardiovascular and Cerebrovascular Diseases and Erectile Dysfunction (NCT07311330) | Beijing Inno Medicine Co., Ltd. | 2026-01-31 |
| Tucatinib and Trastuzumab in HER3-mutant and HER2-not Amplified Metastatic Breast Cancer (NCT07193394) | Institut Curie | 2026-01-31 |
| The Efficacy and Safety of Paclitaxel Monotherapy Versus Paclitaxel-Carboplatin Combination as Neoadjuvant Chemotherapy in Advanced Ovarian Cancer With High PARK2 Expression (NCT07401654) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2026-01-31 |
| Efficacy and Safety of Xeligekimab in the Treatment of Non-Radiographic Axial Spondyloarthritis (NCT07339566) | Lingli Dong | 2026-01-31 |
| Romiplostim Versus rhTPO for Platelet Engraftment After Transplant in MDS and AA (NCT07400341) | The First Affiliated Hospital of Soochow University | 2026-01-31 |
| Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy and Sequential Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer (NCT07349225) | The Second Affiliated Hospital of Dalian Medical University | 2026-01-31 |
| A Phase II Trial of a Recombinant Human Anti-Rabies Virus Monoclonal Antibody (NCT07445815) | Lanzhou Institute of Biological Products Co., Ltd | 2026-01-31 |
| An Open-label, Single-arm, Prospective, Multicenter, Phase I/II Clinical Study on the Safety and Efficacy of CD19/BCMA CAR-T Cell Therapy for Relapsed/Refractory Warm Antibody Autoimmune Hemolytic Anemia (NCT07324889) | Yihao Wang | 2026-01-31 |
| A Phase Ib/II Study to Evaluate HLX43 Combined With HLX07 or Serplulimab in Patients With Advanced or Metastatic Colorectal Cancer (NCT07358585) | Shanghai Henlius Biotech | 2026-01-31 |
| A Phase I/II Study to Evaluate XNW34017 in Patients With Advanced or Metastatic Solid Tumor (NCT07327294) | Evopoint Biosciences Inc. | 2026-01-31 |
| Exploration of Treatment Strategies After Concurrent Chemoradiotherapy for LS-SCLC Guided by MRD (NCT07357532) | Peking University Cancer Hospital & Institute | 2026-01-31 |
| Adebrelimab Combined With Gemcitabine, Cisplatin, and Simvastatin for Advanced Biliary Tract Cancer (NCT07392541) | Tongji Hospital | 2026-01-30 |
| Re-challenge Immunotherapy With Cromolyn, TQB2102, and Panpulimab in Immune-Refractory Triple Negative Breast Cancer (NCT07419880) | Fudan University | 2026-01-30 |
| Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers (NCT07227298) | Pfizer | 2026-01-30 |
| A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or Oligodendroglioma (NCT07120984) | Philogen S.p.A. | 2026-01-30 |
| Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer (NCT06860815) | City of Hope Medical Center | 2026-01-30 |
| Etoricoxib in Patients With Parkinsonian Disease (NCT07370532) | Ihab Elsayed Hassan | 2026-01-30 |
| Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial (NCT07301632) | Unity Health Toronto | 2026-01-30 |
| Zillion: Zanubrutinib Combined With Chemotherapy for Newly Diagnosed CNS Lymphoma (NCT07405255) | Ruijin Hospital | 2026-01-30 |
| Intrauterine Injection of Type III Collage in FST of EC/AEH (NCT07377734) | Wang Jianliu | 2026-01-30 |
| A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Biliary Tract Cancers (NCT07351591) | Eastern Hepatobiliary Surgery Hospital | 2026-01-30 |
| Efficacy and Safety of Intra-Arterial Albumin as Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke (NCT07365475) | Tianjin Huanhu Hospital | 2026-01-30 |
| A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-study (NCT06594393) | Xinnate AB | 2026-01-30 |
| Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors (NCT07397338) | Revolution Medicines, Inc. | 2026-01-30 |
| Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer (NCT07288177) | Genmab | 2026-01-30 |