| A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH) (NCT07325526) | Boehringer Ingelheim | 2026-02-27 |
| A IB/II Phase Clinical Study on the Safety, Tolerability, and Efficacy of SHR-9839(sc) in Combination Anti-tumor Therapy in Patients With Solid Tumors (NCT07229638) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-02-27 |
| A Study to Evaluate HLX22 in Combination With HLX87 in Patients With HER2-Positive Recurrent or Metastatic Breast Cancer (NCT07294508) | Shanghai Henlius Biotech | 2026-02-27 |
| IncobotulinumtoxinA for Provoked Vestibulodynia With Overactive Pelvic Floor Muscle Dysfunction (NCT07486830) | Center for Vulvovaginal Disorders | 2026-02-27 |
| To Evaluate the Efficacy and Safety of JPI-547 in Combination With Bevacizumab as Maintenance Therapy in Relapsed Ovarian Cancer (NCT07370818) | Onconic Therapeutics Inc. | 2026-02-27 |
| A Phase Ib/II Study of ATG-022 Plus Pembrolizumab With/Without Chemotherapy in Participants With Claudin (CLDN) 18.2-positive, HER2-negative, Unresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaUnresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (NCT07327229) | Antengene Biologics Limited | 2026-02-27 |
| Using FAPI PET/MRI to Evaluate Prostate Cancer (NCT06675357) | University of Wisconsin, Madison | 2026-02-27 |
| A Clinical Trial on the Efficacy and Safety of TQB6411 for Injection (NCT07367529) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2026-02-26 |
| Perioperative Chemotherapy With Low-Dose Radiotherapy and Tislelizumab for Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (NCT07408609) | Jiangsu Cancer Institute & Hospital | 2026-02-26 |
| Glutide for Ending Methamphetamine (NCT07204249) | San Francisco Department of Public Health | 2026-02-26 |
| Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide (NCT07454837) | Mirum Pharmaceuticals, Inc. | 2026-02-26 |
| PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease (NCT07069595) | UNC Lineberger Comprehensive Cancer Center | 2026-02-26 |
| A Phase II Trial of LM103 for Adjuvant Treatment in Patients With Non-small Cell Lung Cancer (NCT07444437) | Suzhou BlueHorse Therapeutics Co., Ltd. | 2026-02-26 |
| HS-IT101 Injection Versus Chemotherapy in the Treatment of Advanced Melanoma (NCT07406724) | Qingdao Sino-Cell Biomedicine Co., Ltd. | 2026-02-26 |
| A Phase II Clinical Study of LBL-024 Combination Therapy in Patients With Advanced Solid Tumour[Substudy 03(ESCC)] (NCT07331155) | Nanjing Leads Biolabs Co.,Ltd | 2026-02-26 |
| [18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer (NCT06502691) | University of Washington | 2026-02-26 |
| Brain Blood Vessel Responses to Changes in Blood Flow (NCT06629077) | University of Wisconsin, Madison | 2026-02-26 |
| Zinc Supplementation With Botulinum Toxin for Overactive Bladder (NCT07405554) | Endeavor Health | 2026-02-26 |
| A Clinical Trial of Extended (High) Treatment Dose Antibiotics in Combination With Methenamine Hippurate Compared to the Standard of Care (Either Prophylactic (Low) Dose Antibiotic Treatment or Methenamine Hippurate) in Females With Chronic Urinary Tract Infection (NCT07202949) | University College, London | 2026-02-26 |
| Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery (NCT07443085) | Benha University | 2026-02-26 |
| Trastzumab Deruxtecan Versus SOC in Recurrent Ovarian That Progressed on Prior PARP Inhibitor Therapy (NCT07340164) | Yonsei University | 2026-02-26 |
| Modified Short-Course Radiotherapy Combined With Immunochemotherapy and Targeted Therapy as First-Line Treatment for MSS Metastatic Colorectal Cancer (NCT07512674) | Sir Run Run Shaw Hospital | 2026-02-26 |
| QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Triple-Negative Breast Cancer (NCT07342283) | Affiliated Hospital of Nantong University | 2026-02-25 |
| Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA. (NCT07432867) | Assistance Publique - Hôpitaux de Paris | 2026-02-25 |
| Evaluation of SIRT Followed by Immunotherapy for Treatment of Hepatocellular Carcinoma With Portal Vein Thrombosis (NCT07122089) | Center Eugene Marquis | 2026-02-25 |
| Phase II Clinical Trial Evaluating the Efficacy and Safety of HRS-7249 and SHR-1918 in Patients With Severe Hypertriglyceridemia at High Risk of Acute Pancreatitis (NCT07308392) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2026-02-25 |
| HEALEY ALS Platform Trial - Regimen I NUZ-001 (NCT07410806) | Merit E. Cudkowicz, MD | 2026-02-25 |
| Phase 1/2 Study of a Plant-Based Seasonal Recombinant Trivalent VLP Influenza Vaccine (NCT07291635) | Aramis Biotechnologies Inc. | 2026-02-25 |
| Zoledronic Acid Treatment in Patients With Congenital Dyserythropoietic Anemia (NCT07471516) | Institute of Hematology & Blood Diseases Hospital, China | 2026-02-25 |
| A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations (NCT07432958) | Appello Pharmaceuticals, Inc. | 2026-02-25 |
| CAT-VHL Exploring the Role of Carbonic Anhydrase IX as Diagnostic and Theranostic Target in Von-Hippel Lindau Disease (NCT07171905) | IRCCS Ospedale San Raffaele | 2026-02-25 |
| Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer (NCT07405736) | Sun Yat-sen University | 2026-02-24 |
| Anlotinib Combined With Sintilimab as First-line Treatment for Advanced Non-liver Metastatic Colorectal Cancer (NCT07398326) | Shanghai Changzheng Hospital | 2026-02-24 |
| Accelerated dTMS Smoking Cessation (NCT07292883) | Waypoint Centre for Mental Health Care | 2026-02-24 |
| Trial of ONC-PluReceptor NK Cells With Epcoritamab and Tafasitamab for Patients With Recurrent or Refractory B-cell Non-Hodgkin Lymphoma (NCT07283679) | M.D. Anderson Cancer Center | 2026-02-24 |
| SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma (NCT07104331) | Sarcoma Alliance for Research through Collaboration | 2026-02-24 |
| Efficacy and Safety of HAIC Combined With Lenvatinib and PD-1 Inhibitors for Advanced Intrahepatic Cholangiocarcinoma (NCT07646717) | Tianjin Medical University Cancer Institute and Hospital | 2026-02-24 |
| Sacituzumab Tirumotecan Plus Anlotinib in Previously Treated ES-SCLC (NCT07388875) | China Medical University, China | 2026-02-24 |
| Study of Sacituzumab Tirumotecan Combined With Toripalimab for Resectable Stage II-IIIB NSCLC (NCT07438600) | Tianjin Medical University Cancer Institute and Hospital | 2026-02-24 |
| Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo (NCT06694740) | Assistance Publique - Hôpitaux de Paris | 2026-02-24 |
| Treatment of Immune Checkpoint Inhibitor-related Diarrhea and/ or Colitis With Ustekinumab in Cancer Patients (NCT06807593) | M.D. Anderson Cancer Center | 2026-02-24 |
| Durvalumab as Consolidation for Patients LS-SCLC (NCT07055581) | Qian Chu | 2026-02-24 |
| A Study to Evaluate Safety, PK and Efficacy of GH55 in Combination With GH21 in Patients With Solid Tumors (NCT07446725) | Suzhou Genhouse Bio Co., Ltd. | 2026-02-24 |
| A Trial of Tegileridine Fumarate Lnjection for Prolonged Mechanical Ventilation Abirritation in the Intensive Care Unit (ICU) (NCT07372924) | Jiangsu HengRui Medicine Co., Ltd. | 2026-02-24 |
| Effect of a Daily Supplement on Plasma PAI-1 Levels (NCT07469475) | University of California, Los Angeles | 2026-02-24 |
| PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia (NCT07101640) | Duke University | 2026-02-23 |
| REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients) (NCT07302451) | National Cancer Institute, Naples | 2026-02-23 |
| 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors (NCT07189871) | Radiopharm Theranostics, Ltd | 2026-02-23 |
| A Study to Learn About mRNA Vaccines Against Influenza in Adults (NCT07431853) | Pfizer | 2026-02-23 |
| Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC (NCT06681220) | VA Office of Research and Development | 2026-02-23 |
| An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis (NCT07449702) | Oruka Therapeutics, Inc. | 2026-02-23 |
| Effects of Melatonin on Excessive Crying in Neonates. A Randomized Controlled Clinical Trial. (NCT07442162) | Al-Hadba university | 2026-02-23 |
| Bevacizumab Plus Nab-paclitaxel and Tegafur Gimeracil Oteracil Potassium Capsule (S-1) as Second-line Treatment for Advanced Biliary Tract Cancer: a Phase Ⅱ Clinical Trial (NCT07719738) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-02-23 |
| BXCL501 After Stress to Increase Recovery Success (NCT06943404) | University of North Carolina, Chapel Hill | 2026-02-23 |
| Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Without Concurrent Surufatinib in Neoadjuvant Therapy for Mid-to-low Localized Rectal Cancer of High-risk Criteria (NCT07505472) | The First Hospital of Jilin University | 2026-02-23 |
| Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes (NCT07186660) | University of Virginia | 2026-02-22 |
| Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer (NCT06900595) | National Cancer Institute (NCI) | 2026-02-22 |
| A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (NCT06842498) | Kyntra Bio | 2026-02-22 |
| Acetohydroxamic Acid Combined With a Short-Course Regimen for MDR-TB (AHA-PLUS) (NCT07393438) | Shanghai Pulmonary Hospital, Shanghai, China | 2026-02-21 |
| Conversion Surgery for Gastric Cancer With Peritoneal Metastases (CONVERGENCE) (NCT07241715) | National University Hospital, Singapore | 2026-02-21 |
| Erythrodiol in Pomace Olive Oil as a Protective Agent Against Atherosclerosis (NCT07422051) | Spanish National Research Council | 2026-02-21 |
| Phase II Exploratory Study of Toripalimab Combined With SBRT in HER2-Negative Breast Cancer Patients With Insensitivity to Neoadjuvant Chemotherapy (NCT07410234) | Tianjin Medical University Cancer Institute and Hospital | 2026-02-21 |
| Multimodal Imaging With FAPI-PET/MRI in Breast Carcinoma-In-Situ for Detection of Occult Invasive Cancer (NCT06540872) | Universität Münster | 2026-02-20 |
| Comparison of Functional Outcomes Following Arthroscopic ACL Reconstruction With Peroneus Longus Autograft With and Without Intra-articular Platelet-Rich Plasma Injection. (NCT07470359) | Lahore General Hospital | 2026-02-20 |
| Safety and Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells in Preventing Arteriovenous Fistula Stenosis in Patients With End-Stage Diabetic Kidney Disease (NCT07452822) | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 2026-02-20 |
| Immune Tolerance Induction After Liver Transplantation (NCT07269041) | University of California, Los Angeles | 2026-02-20 |
| Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation (NCT07354477) | Qlaris Bio, Inc. | 2026-02-20 |
| Study of DISC-0974-201 in Participants With IBD and Anemia (NCT07368972) | Disc Medicine, Inc | 2026-02-20 |
| A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in Africa (NCT07379580) | BioNTech SE | 2026-02-20 |
| The Safety and Efficacy of the Regimen of Thiotepa + Fludarabine +Granulocyte Colony-Stimulating Factor+ Cytarabine + Busulfan in Single Unrelated Umbilical Cord Blood Transplantation (NCT07441967) | Institute of Hematology & Blood Diseases Hospital, China | 2026-02-20 |
| Biased GRK Signaling Via β2-Adrenergic Receptors in Human Skeletal Muscle (NCT07421024) | Morten Hostrup, PhD | 2026-02-20 |
| A Study of Nemolizumab for the Treatment of Adults With Systemic Sclerosis (NCT07047690) | Galderma R&D | 2026-02-20 |
| Phase II Study of CMS-D002 Capsule for Uterine Fibroids With Menorrhagia (NCT07402369) | Shenzhen Kangzhe Biotechnology Co., Ltd. | 2026-02-19 |
| [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications (NCT07432633) | Blue Earth Diagnostics | 2026-02-19 |
| Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer (NCT07323641) | Jonsson Comprehensive Cancer Center | 2026-02-19 |
| A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis (NCT07568730) | TearSolutions, Inc. | 2026-02-19 |
| Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS (NCT07743268) | n-Lorem Foundation | 2026-02-19 |
| Equol and Vascular Function in Women With Chronic Kidney Disease (NCT07194590) | University of Colorado, Denver | 2026-02-19 |
| Sense4Safety Intervention (NCT07220668) | University of Pennsylvania | 2026-02-19 |
| Comparing Adjuvant Treatments for High Tone Pelvic Floor Dysfunction (NCT07404397) | University of Michigan | 2026-02-18 |
| Dose Finding Trial of R21/Matrix-M in School Children (NCT07074665) | University of Oxford | 2026-02-18 |
| A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma (NCT07284758) | C4 Therapeutics, Inc. | 2026-02-18 |
| SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas (NCT07222631) | University of California, San Diego | 2026-02-18 |
| UKK-0018 as an Immunotherapeutic for Treatment of Peanut Allergies (NCT07349212) | Ukko Inc | 2026-02-18 |
| Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus (NCT06981767) | Cairo University | 2026-02-18 |
| Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) (NCT07209189) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2026-02-18 |
| To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer (NCT07368998) | Hoffmann-La Roche | 2026-02-18 |
| Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological Involvement (NCT06923072) | National Heart, Lung, and Blood Institute (NHLBI) | 2026-02-18 |
| Tolerance Results and Immune Mechanisms in Cow´s Milk and/or Hen´s Egg Allergic Children Following Natural Evolution or Oral Immunotherapy (NCT07419243) | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | 2026-02-18 |
| Trastuzumab Deruxtecan in First-Line HER2-Positive Metastatic Breast Cancer With Proactive Toxicity Management (NCT07371585) | SOLTI Breast Cancer Research Group | 2026-02-18 |
| A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY) (NCT07409103) | Elevara Medicines Limited | 2026-02-18 |
| Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy (NCT07461220) | Integrative Research Laboratories AB | 2026-02-18 |
| Preoperative Botulinum Toxin A to Facilitate Midline Closure in Large Chronic Ventral Hernias (NCT07628205) | Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano | 2026-02-17 |
| CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors (NCT07335497) | Crescent Biopharma, Inc. | 2026-02-17 |
| CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer (NCT06730100) | National Cancer Institute (NCI) | 2026-02-17 |
| Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma (NCT07463599) | HonorHealth Research Institute | 2026-02-17 |
| Effect of Melatonin on Oxidative Stress Parameters in Levodopa-Treated Parkinson's Disease Patients (NCT07375693) | Bangladesh Medical University | 2026-02-17 |
| Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia (NCT07288333) | Neurocrine Biosciences | 2026-02-16 |
| Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies (NCT07340541) | UNC Lineberger Comprehensive Cancer Center | 2026-02-16 |
| Inflammatory Challenge in Human Aggression. (NCT06665074) | Ohio State University | 2026-02-16 |