| An Open-label, Randomized Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of the Combination Therapy of SLC-3010 and Axitinib Compared to Axitinib Monotherapy as a Second-line Treatment for Locally Advanced or Metastatic Clear Cell Renal Cell Carcinoma (NCT07469683) | Yonsei University | 2026-03-01 |
| Cefotetan Therapy for Escherichia Coli Infections (NCT07318584) | Oregon Health and Science University | 2026-03-01 |
| Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis (NCT07477639) | Tr1X, Inc. | 2026-03-01 |
| A Study to Investigate the Effects and Safety of SPG601 for the Treatment of Fragile X Syndrome in Male Participants (NCT07439510) | Spinogenix | 2026-03-01 |
| Localized Injection of Lidocaine Via the Middle Meningeal Artery for Intractable Headache Treatment (NCT07361549) | Daniel A Tonetti, MD | 2026-03-01 |
| L9LS-R21 Interaction (NCT07208760) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-03-01 |
| Prospective Management of Plaque Instability With Statins and Extra Folic Acid (NCT07680595) | Ruijin Hospital | 2026-03-01 |
| Xenon Therapy for Children With Autism Spectrum Disorder (NCT07435103) | The Children's Hospital of Zhejiang University School of Medicine | 2026-03-01 |
| Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer (NCT07369986) | Women's Hospital School Of Medicine Zhejiang University | 2026-03-01 |
| Evaluation of the Efficacy and Onset of Action of a Topical Anesthetic Marker (NCT07273916) | Hexsel Dermatology Clinic | 2026-03-01 |
| Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE) (NCT07435584) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-03-01 |
| A Phase II/III Clinical Study to Evaluate HLX07 in Combination With Serplulimab and Chemotherapy Versus Placebo in Combination With Serplulimab or Pembrolizumab and Chemotherapy as First-Line Treatment in Advanced Squamous Non-Small Cell Lung Cancer (NCT07318883) | Shanghai Henlius Biotech | 2026-03-01 |
| Safety and Efficacy of PSMA-Targeted Fluorescent Contrast Agent DGPR1008 for Intraoperative Imaging in Robot-Assisted Radical Prostatectomy (NCT07415135) | Zhu Yinjie | 2026-03-01 |
| Bacteriophage Therapy for Staphylococcus Lugdunensis Prosthetic Joint Infection (NCT07461337) | University of Calgary | 2026-03-01 |
| Rimegepant Combined With AG Chemotherapy As First-Line Treatment For Metastatic Pancreatic Ductal Adenocarcinoma (NCT07475234) | Xiuchao Wang | 2026-03-01 |
| Comparison of 18F Labeled Analog of MIBG (18F-MFBG) PET/CT and 123I-MIBG SPECT in Pediatric Patients With Neuroblastoma. (NCT07111117) | Institut Curie | 2026-03-01 |
| Grouping Immune-modulation With Cryoablation (LOGIC) for Breast Cancers (NCT05806385) | Texas Tech University Health Sciences Center | 2026-03-01 |
| Efficacy and Safety of Lisafotoclax Plus Decitabine and Homoharringtonine in Venetoclax/Azacitidine Pretreated AML Patients (NCT07505160) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-03-01 |
| Trastuzumab Rezetecan vs Trastuzumab Deruxtecan in the Neoadjuvant Treatment of HER2 Positive Breast Cancer (NCT07416253) | Henan Cancer Hospital | 2026-03-01 |
| ASCs in Recently Diagnosed Non-ischemic Heart Failure (NCT06840275) | Cell to Cure ApS | 2026-03-01 |
| Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma. (NCT07439172) | The Cooper Health System | 2026-03-01 |
| Evaluation of Pressurized Intraperitoneal Aerosol Chemotherapy With VRT106 Versus PIPAC in Patients With Advanced Gastric Cancer and PeritonealMetastasis: A Prospective, Multicenter, Open-Label, Randomized Controlled Trial (NCT07486310) | Guangdong Provincial People's Hospital | 2026-03-01 |
| Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of Trapeziometacarpal Osteoarthritis (NCT07435571) | TBF Genie Tissulaire | 2026-03-01 |
| Orelabrutinib Combined With Standard Immunochemotherapy With or Without Autologous Hematopoietic Stem Cell Transplantation (Auto-HSCT) for Newly Diagnosed Diffuse Large B-cell Lymphoma (DLBCL) (NCT07680933) | The Affiliated Hospital of Xuzhou Medical University | 2026-03-01 |
| A Phase II Prospective Study of Maastro Applicator Brachytherapy for Rectal Cancer (NCT07402486) | Siriraj Hospital | 2026-03-01 |
| SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer (NCT07391813) | SN BioScience | 2026-03-01 |
| A Phase 2 Study to Assess the Effectiveness of Topical Terbinafine in Participants With Mild to Moderate Onychomycosis of the Toenails (NCT07382427) | Onyx Axiom | 2026-03-01 |
| Efficacy of Triamcinolone-Lidocaine Mix in Trigger Points Injection of Masseter Muscle: Double-blinded, Randomized Controlled Trial (NCT07445191) | Cairo University | 2026-03-01 |
| Personalized Antisense Oligonucleotide Therapy for A Single Patient With CHCHD10 ALS (nL18576) (NCT07423494) | n-Lorem Foundation | 2026-03-01 |
| Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE) (NCT07226440) | University of California, San Francisco | 2026-03-01 |
| The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions in Adolescent Patients With Retinitis Pigmentosa (NCT02018692) | Sheba Medical Center | 2026-03-01 |
| Pembrolizumab and Lenvatinib in Patients With High Risk Locally Advanced Cervix Cancer (NCT07368985) | Prof. Dr. Remi A. Nout | 2026-03-01 |
| 6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial Tumors (NCT07463313) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2026-03-01 |
| First-line Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma With Dual Immunotherapy Combined With Chemotherapy (NCT07400315) | The First Affiliated Hospital with Nanjing Medical University | 2026-03-01 |
| Neoadjuvant Aitua (PD-1/CTLA-4 Bispecific) Plus Nab-Paclitaxel and Carboplatin for Advanced High-Grade Serous Ovarian Cancer (NCT07432594) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-03-01 |
| Orelabrutinib in the Treatment of Relapsed/Refractory AIHA (NCT07453368) | Peking Union Medical College Hospital | 2026-03-01 |
| Daratumumab Versus Rituximab in the Management of Pediatric Primary Immune Thrombocytopenia (ITP) (NCT07362238) | Institute of Hematology & Blood Diseases Hospital, China | 2026-03-01 |
| A Phase I/II Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of the EMB-07 Combination Therapy in Patients With Aggressive B-Cell Non-Hodgkin Lymphoma (NCT07432022) | Shanghai EpimAb Biotherapeutics Co., Ltd. | 2026-03-01 |
| Cadonilimab Combined With RT in LACC Patients Ineligible for CCRT (NCT07450963) | Ruijin Hospital | 2026-03-01 |
| Ketamine for Veterans With Parkinson's Disease (NCT06231563) | VA Office of Research and Development | 2026-03-01 |
| Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome (NCT07328529) | Azevan Pharmaceuticals | 2026-03-01 |
| Long-Term Safety and Efficacy of HSK39004 Dry Powder Inhaler in COPD (NCT07425210) | Haisco Pharmaceutical Group Co., Ltd. | 2026-03-01 |
| ASCT With TEAM Conditioning for Lymphoma With High Risk of CNS Relapse (NCT07481669) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-03-01 |
| Comparing the Efficacy of the LDA, LHAA, and DA Regimens in Young Adults With Low-Risk Acute Myeloid Leukemia Eligible for Intensive Chemotherapy (NCT07651176) | First Affiliated Hospital of Zhejiang University | 2026-03-01 |
| Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids (NCT06882772) | University of Nebraska | 2026-03-01 |
| Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases (NCT05029336) | Stephan Grupp MD PhD | 2026-03-01 |
| Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners (NCT07384156) | Penn State University | 2026-03-01 |
| Glecirasib Combined With Ivonescimab for First-line Treatment of KRAS G12C-mutated NSCLC (NCT07339839) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-03-01 |
| Advancing Reperfusion Therapy for Ischemic Stroke: Safety and Efficacy of Anakinra for Futile Reperfusion Following Endovascular Treatment in Patients With Acute Ischemic Stroke (NCT07423975) | Beijing Tiantan Hospital | 2026-03-01 |
| Topical Periplaneta Americana-Derived Meilian Fuxin Liquid for Radiation Dermatitis (NCT07353671) | West China Hospital | 2026-03-01 |
| Liposomal Irinotecan, Vincristine, Temozolomide, and Anlotinib for R/R Pediatric Solid Tumors (NCT07444918) | Tianjin Medical University Cancer Institute and Hospital | 2026-03-01 |
| Glofitamab Combined With CAR-T Therapy in R/R DLBCL (NCT07326371) | Ruijin Hospital | 2026-03-01 |
| Efficacy and Safety of TC011 in Relapsed or Refractory Follicular Lymphoma (NCT07360288) | TICAROS Co., Ltd. | 2026-03-01 |
| A Platform Study Based on Specific Tracer for Evaluating the Therapeutic Efficacy of Systemic Treatment for Breast Cancer Using PET/MRI (NCT07419867) | Fudan University | 2026-03-01 |
| IBI363 Plus Bevacizumab With or Without Nab-Paclitaxel for Second-Line Treatment of Advanced Gastric Cancer (NCT07361991) | The First Affiliated Hospital of Zhengzhou University | 2026-03-01 |
| Adebrelimab Maintenance Therapy for LS-SCLC Post Induction Chemo-Adebrelimab Plus CRT or CRT Alone (NCT07381543) | Peking University Cancer Hospital & Institute | 2026-03-01 |
| Chidamide Combined With Chemotherapy and Immunotherapy as First-line Treatment for Advanced Intrahepatic Cholangiocarcinoma (NCT07570849) | Shanghai Zhongshan Hospital | 2026-03-01 |
| A Prospective, Single-Arm, Phase II Study: PD-L1 Monoclonal Antibody + Chemoradiotherapy as Bridge Therapy to Liver Transplantation for Locally Advanced Perihilar Cholangiocarcinoma (ACHIEVE-LT) (NCT07471165) | The First Affiliated Hospital with Nanjing Medical University | 2026-03-01 |
| Comparing the Efficacy of LDA, LHAA, and LA Regimens in Young Adults With Intermediate- and High-Risk Acute Myeloid Leukemia Eligible for Intensive Chemotherapy (NCT07651163) | First Affiliated Hospital of Zhejiang University | 2026-03-01 |
| Efficacy and Safety of Tazbentetol in ALS Participants (NCT07325591) | Spinogenix | 2026-03-01 |
| Lung Functional Avoidance Radiotherapy Using Hyperpolarized Xenon MRI (NCT07355231) | Xemed LLC | 2026-03-01 |
| Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer (NCT07409844) | Ismail Gögenur | 2026-03-01 |
| A Study of BL-M11D1 in Combination With Cytarabine + Daunorubicin or Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia (NCT07255872) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-03-01 |
| Treatment of Severe Ocular Chemical Burns by Subconjunctival Injection of Allogeneic Mesenchymal Stem Cells: An Open-Label, Single-Arm, Multicenter Phase II Trial (NCT07329569) | Fondation Ophtalmologique Adolphe de Rothschild | 2026-03-01 |
| A Study of BR1400-1, BR1400-2, BR1400-3, BR1400-4, and BR1400-5 in Patients With Essential Hypertension (NCT07373613) | Boryung Pharmaceutical Co., Ltd | 2026-03-01 |
| TAR-0520 Gel in Hand and Foot Syndrome (NCT07457671) | Tarian Pharma | 2026-03-01 |
| Neoadjuvant Serplulimab Plus Weekly Paclitaxel and Carboplatin in TNBC (Neo-SERPENT) (NCT07283692) | RenJi Hospital | 2026-03-01 |
| Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer (NCT07397442) | Beijing Friendship Hospital | 2026-03-01 |
| Topical Use of 2% Tofacitinib for Nail Psoriasis: an Exploratory Clinical Study (NCT07313072) | Hexsel Dermatology Clinic | 2026-03-01 |
| Study to Assess the Safety and Effectiveness of Novel Radiopharmaceutical Terbium-161 DOTATATE in Metastatic Neuroendocrine Tumors (NCT07404176) | Tata Memorial Hospital | 2026-03-01 |
| Clinical Evaluation of Subcutaneous Testosterone Implants in Men With Symptomatic Hypogonadism (NCT07500766) | University of Sao Paulo | 2026-03-01 |
| PD-1 Antibody-based Therapy With Concurrent RT for Early-stage NKTCL (NCT07380984) | Ruijin Hospital | 2026-03-01 |
| Monitoring Early Response to Targeted Therapy in Stage IV HER2+ Breast Cancer Patients With Advanced PET/MR Imaging (NCT04273555) | University of Alabama at Birmingham | 2026-03-01 |
| Irinotecan-ChemoSeed in Surgically Resectable Glioblastoma (NCT07356973) | CRISM Therapeutics LTD | 2026-03-01 |
| A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection (NCT03038802) | Vaxine Pty Ltd | 2026-03-01 |
| A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy (NCT06286046) | Agios Pharmaceuticals, Inc. | 2026-03-01 |
| Deep Sleep in Older Adults (NCT07316153) | Proactive Life Inc | 2026-03-01 |
| Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain (NCT07470606) | The University of Texas Health Science Center at San Antonio | 2026-03-01 |
| Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser (NCT07472192) | Misr University for Science and Technology | 2026-03-01 |
| Iparomlimab/Tuvonralimab + Standard Chemotherapy and Olaparib in Platinum-Sensitive Recurrent Ovarian Cancer (NCT07454018) | The First Affiliated Hospital of Soochow University | 2026-03-01 |
| Exercise Training for Brachial Plexus Injury Following Nerve Transfer (NCT05859178) | University of Alberta | 2026-03-01 |
| A Study of BEBT-701 in Patients With Mild to Moderate Hypertension and Elevated Low-Density Lipoprotein Cholesterol（LDL-C） (NCT07368608) | BeBetter Med Inc | 2026-03-01 |
| A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CDI-988 in Healthy Adults After Challenge With Snow Mountain Virus (NCT07198139) | Cocrystal Pharma, Inc. | 2026-03-01 |
| Study on the Safety and Efficacy of Intratympanic Injection of Small Extracellular Vesicles Derived From Mesenchymal Stem Cells in Severe and Profound Sudden Sensorineural Hearing Loss (NCT07404709) | The Affiliated Hospital of Qingdao University | 2026-02-28 |
| Fluzoparib Plus Famitinib Maintenance After First-Line Platinum Response in Advanced Ovarian Cancer (NCT07382713) | Jinhua Zhou | 2026-02-28 |
| A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Asthma (NCT07436221) | Akeso | 2026-02-28 |
| Abbreviated Biparametric MRI (RSI + T2WI) for Prostate Cancer Detection: Correlation With Histopathology (NCT05046782) | M.D. Anderson Cancer Center | 2026-02-28 |
| Lisatoclax Plus R-CHOP or Pola-R-CHP in Untreated DLBCL: A Phase Ib/II Study (NCT07398638) | Sun Yat-sen University | 2026-02-28 |
| RBD5044 in Chinese Participants With Hypertriglyceridemia (NCT07587788) | Ribotek Biopharmaceuticals (Shandong) Co., Ltd | 2026-02-28 |
| Safety and Efficacy of Umbilical Cord Blood Therapy for Cancer Therapy-Induced Thrombocytopenia (CTIT) (NCT07441720) | Zhejiang Cancer Hospital | 2026-02-28 |
| Safety and Efficacy of a Single Dose of Gruticibart to Prevent CRT (NCT07498517) | OHSU Knight Cancer Institute | 2026-02-28 |
| SYS6090 Combination Therapy in Advanced Lung Cancer (NCT07472647) | Shanghai JMT-Bio Inc. | 2026-02-28 |
| To studyJUV-161 Administered to Healthy Volunteers Undergoing Unilateral Lower Limb Immobilization (ULLI) (NCT07397468) | Juvena Therapeutics | 2026-02-28 |
| IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors (NCT07441174) | InxMed (Shanghai) Co., Ltd. | 2026-02-28 |
| Tirzepatide to Slow Biological Aging (NCT07220473) | The University of Texas Medical Branch, Galveston | 2026-02-27 |
| Study to Assess the Efficacy of EMC-CAP-2025A on Age-Related Skin Parameters in Healthy Individuals (NCT07493850) | Circul'Egg | 2026-02-27 |
| To Evaluate the Safety and Tolerability of Study Drug as a Third-line and Beyond Therapy for Recurrent or Metastatic Gastric Cancer (NCT07364422) | Onconic Therapeutics Inc. | 2026-02-27 |
| PSMA-Targeted Intraoperative Fluorescent Imaging Agents (DGPR1008): Validation Across Different Time Windows (NCT07387510) | Haitao Niu, MD | 2026-02-27 |
| N2O for Acute Suicidality and Depression in the ED (NCT05710887) | University of Chicago | 2026-02-27 |
| A Study of Elranatamab and Cyclophosphamide in People With Multiple Myeloma (NCT07454382) | Memorial Sloan Kettering Cancer Center | 2026-02-27 |