| Topical Chinese Medicine and Exosome Mechanisms for Atopic Dermatitis (NCT07693400) | Taiwan Municipal An-Nan Hospital-China Medical University | 2026-04-29 |
| Phase 2 Trial of a Haemophilus Influenzae Serotype a (Hia) Glycoconjugate Vaccine (NCT07743008) | InventVacc Biologicals Inc. | 2026-04-29 |
| Lipid Infusions to Optimize Nutrition Trial (NCT06915441) | The University of Texas Health Science Center, Houston | 2026-04-29 |
| Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer (NCT07670273) | Peking Union Medical College Hospital | 2026-04-29 |
| A Phase II Clinical Trial of SHR-1826 for Non-Small Cell Lung Cancer (NCT07489716) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-04-29 |
| A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to Prevent Lyme Disease in Healthy Participants (18 to 70 Years of Age) (NCT07561294) | ModernaTX, Inc. | 2026-04-29 |
| A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC) (NCT07188896) | Brian Rini | 2026-04-29 |
| Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Carcinoma Subtype I (ACC-I) (NCT07162480) | M.D. Anderson Cancer Center | 2026-04-29 |
| Safety and Performance of a Novel Infusion Catheter System for Peri/Intratumoral Gemcitabine Delivery in Patients With Pancreatic Cancer (NCT07575191) | Smartwise Sweden AB | 2026-04-29 |
| A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C) (NCT07545772) | Eli Lilly and Company | 2026-04-29 |
| Anifrolumab in Adults With Primary Antiphospholipid Syndrome (AnifAPS Trial) (NCT07584083) | National and Kapodistrian University of Athens | 2026-04-29 |
| Fecal Microbiota Transplantation for Steroid-Refractory Acute GI GVHD (NCT07364617) | Chang Gung Memorial Hospital | 2026-04-29 |
| A Study of LTX-002 in Adult Participants With Amyotrophic Lateral Sclerosis (NCT07660614) | Leal Therapeutics, Inc | 2026-04-29 |
| Androgen-responsive POSLUMA-guided Intra-prostatic Boost (NCT07393867) | Martin T. King, MD, PhD | 2026-04-29 |
| A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer (NCT07567846) | Genentech, Inc. | 2026-04-29 |
| Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma (NCT07000253) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2026-04-29 |
| Prospective Clinical Trial of 177Lu-P17-088 in the Treatment of Metastatic Castration-Resistant Prostate Cancer (NCT07562438) | First Affiliated Hospital of Fujian Medical University | 2026-04-29 |
| Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies (NCT07427017) | Northwestern University | 2026-04-29 |
| SBRT-LATTICE-PATHY (NCT07645261) | University of Sao Paulo General Hospital | 2026-04-28 |
| Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABG (NCT07192211) | Rohto Pharmaceutical Co., Ltd. | 2026-04-28 |
| Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis (NCT07497399) | Johns Hopkins University | 2026-04-28 |
| Hypofractionated Definitive Chemoradiotherapy for Oesophageal Cancer (NCT07632079) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2026-04-28 |
| Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia (NCT07311746) | M.D. Anderson Cancer Center | 2026-04-28 |
| Iparomlimab and Tuvonralimab Combined With SFRT and Definitive Chemoradiotherapy in Locoregionally Advanced Bulky HNSCC (NCT07041788) | Second Affiliated Hospital of Nanchang University | 2026-04-28 |
| Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP (NCT07354074) | Novartis Pharmaceuticals | 2026-04-28 |
| Cord Blood Transplantation in Children and Young Adults With Blood Cancer (NCT07566377) | Memorial Sloan Kettering Cancer Center | 2026-04-28 |
| A Trial of Trastuzumab Rezetecan in Unresectable Locally Recurrent/Metastatic Breast Cancer (NCT07497386) | Jiangsu HengRui Medicine Co., Ltd. | 2026-04-28 |
| Descartes-08 in Autoantibody Myositis (NCT07391605) | Cartesian Therapeutics | 2026-04-28 |
| A Study of Becotatug Vedotin (MRG003) Combined With Epirubicin as Neoadjuvant Therapy for EGFR-Positive, Unresectable Recurrent Sinonasal Adenoid Cystic Carcinoma (NCT07522879) | Eye & ENT Hospital of Fudan University | 2026-04-28 |
| Axelopran for Advanced Cancer in Patients Receiving Opioids (NCT07354919) | HealthPartners Institute | 2026-04-27 |
| An Open-Label, Double-Treatment Group Study to Evaluate the Efficacy and Safety of Human Allogeneic Bone-Marrow- Derived Mesenchymal Stromal Cell Product StromaForte Compared With Hyaluronic Acid for the Treatment of Knee Osteoarthritis (NCT07542808) | Cellcolabs Clinical SPV Limited | 2026-04-27 |
| A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran (NCT07553442) | Alnylam Pharmaceuticals | 2026-04-27 |
| A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Before Surgery for Men Who Have High-risk Localized Prostate Cancer. (NCT07450599) | Bayer | 2026-04-27 |
| Concurrent Neoadjuvant Chemo/Endocrine Therapy in HER2+ Breast Cancer (NCT07506876) | Legacy Health System | 2026-04-27 |
| Safety, Immunogenicity, and Efficacy of Therapeutic Mycobacterium Bovis BCG (BOOST) (NCT07094711) | University of Virginia | 2026-04-27 |
| Open-Label Study of Dimethyl Fumarate in Adults With Type 1 Diabetes (NCT07548996) | Nanjing Medical University | 2026-04-27 |
| Sex Differences in Neurobehavioral Response to THC (NCT07225777) | Medical University of South Carolina | 2026-04-27 |
| A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Response and Resistance in Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) (NCT07408063) | University Health Network, Toronto | 2026-04-27 |
| Phase II Clinical Study of BC006 in Patients With Idiopathic Pulmonary Fibrosis (NCT07447102) | Dragonboat Biopharmaceutical Company Limited | 2026-04-27 |
| An Experimental Study of Belzutifan Impact on Catecholamine Metabolism (NCT07680205) | Cambridge University Hospitals NHS Foundation Trust | 2026-04-27 |
| SHR-3821 in Advanced Colorectal Cancer: an Exploratory Study (NCT07515820) | Meng Qiu | 2026-04-27 |
| Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma (NCT07225985) | Fred Hutchinson Cancer Center | 2026-04-27 |
| Evaluate the Efficacy and Safety of ICP-488 in Subjects With Cutaneous Lupus Erythematosus (CLE) Double-blind Study (NCT07440537) | Beijing InnoCare Pharma Tech Co., Ltd. | 2026-04-27 |
| Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder (NCT05652465) | National Institute of Mental Health (NIMH) | 2026-04-25 |
| Phase II Study of HLX43 Monotherapy or Combined With Immune Checkpoint Inhibitors in Patients With Locally Advanced, Recurrent, or Metastatic Triple-negative Breast Cancer. (NCT07487519) | Shanghai Henlius Biotech | 2026-04-25 |
| Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer (NCT07328490) | National Cancer Institute (NCI) | 2026-04-25 |
| ASCiminib, With or Without Dasatinib Combination, as a 2nd-Line Therapy to ADVANCE the Treatment for Chronic Myelogenous Leukemia in Chronic Phase (ASC2ADVANCE) (NCT07538401) | University Health Network, Toronto | 2026-04-25 |
| JS212 Combination Therapies in Metastatic Colorectal Cancer (NCT07503756) | Shanghai Junshi Bioscience Co., Ltd. | 2026-04-25 |
| First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion (NCT07332858) | Gang Hou | 2026-04-24 |
| Sintilimab Combined With Ipilimumab (N01) Plus AG as First-line Therapy for uBTC. (NCT07654530) | Tianjin Medical University Cancer Institute and Hospital | 2026-04-24 |
| Terbinafine for Biochemically Recurrent Prostate Cancer (TerbinaPro) (NCT07365423) | Swiss Cancer Institute | 2026-04-24 |
| Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer (NCT07195734) | National Cancer Institute (NCI) | 2026-04-24 |
| Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease (NCT07547930) | The First Affiliated Hospital of Xiamen University | 2026-04-24 |
| Phase 2 Study to Assess the Safety and Efficacy of ANG003 (NCT07450547) | Anagram Therapeutics, Inc. | 2026-04-24 |
| Improvement Effect of Dexamethasone Enema for Acute Radiation-induced Rectal Injury (NCT07548736) | Sixth Affiliated Hospital, Sun Yat-sen University | 2026-04-24 |
| Pregnenolone as a Treatment for Cannabis Intoxication (NCT07216690) | Johns Hopkins University | 2026-04-24 |
| SHR-1701 Combined With Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis (NCT07384234) | Ruijin Hospital | 2026-04-24 |
| Lorlatinib Plus Local Consolidation Therapy In ALK Positive Advanced Non-Small Cell Lung Cancer (NCT07415005) | M.D. Anderson Cancer Center | 2026-04-24 |
| PBGENE-DMD Phase 1/2a Safety and Preliminary Efficacy Study in Duchenne Muscular Dystrophy (FUNCTION-DMD) (NCT07429240) | Precision BioSciences, Inc. | 2026-04-24 |
| Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia (NCT07393373) | QED Therapeutics, a BridgeBio company | 2026-04-23 |
| A Phase 2 Clinical Study of Ziftomenib in Patients With Relapsed or Refractory NPM1-Mutated Acute Myeloid Leukemia (NCT07623616) | Kyowa Kirin Co., Ltd. | 2026-04-23 |
| A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies (NCT07271667) | Curis, Inc. | 2026-04-23 |
| A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV (NCT07143968) | Naga P. Chalasani | 2026-04-23 |
| Vebectotamab Vedotin Combined With Pucotelimab in the Treatment of Locally Advanced Laryngeal Carcinoma (NCT07538206) | Tang-Du Hospital | 2026-04-23 |
| Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below (NCT07561125) | International Peace Maternity and Child Health Hospital | 2026-04-23 |
| Phase 1/2a Study of RP-001 in Participants With Advanced Malignancies (NCT07504263) | Recurv Pharma Inc | 2026-04-23 |
| Phase II Study of JS212/JS213 as Monotherapy and in Combination in Patients With Advanced Malignant Solid Tumors (NCT07480733) | Shanghai Junshi Bioscience Co., Ltd. | 2026-04-23 |
| SKB103 for Injection in Advanced Solid Tumors (NCT07459998) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2026-04-23 |
| Effect of Roflumilast and Desloratadine as Add-On Therapy in Patients With Rheumatoid Arthritis (NCT07566351) | Horus University | 2026-04-23 |
| Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis (NCT07303777) | Atom Therapeutics Co., Ltd | 2026-04-23 |
| Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity (NCT07228741) | St. Jude Children's Research Hospital | 2026-04-23 |
| INSPIRE: INnovative SABR for Prostate Cancer All IREland (NCT07552168) | Cancer Trials Ireland | 2026-04-23 |
| A Phase II Clinical Study on the Efficacy and Safety of HRS-1780 in Participants With Primary Aldosteronism (NCT07470983) | Shandong Suncadia Medicine Co., Ltd. | 2026-04-23 |
| Neoadjuvant Short-course Radiotherapy Followed by a Combination of Disitamab Vedotin, Sintilimab, and Capecitabine in Locally Advanced HER2-expressing Rectal Cance (NCT07509424) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2026-04-22 |
| A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder (NCT07478744) | Synendos Therapeutics AG | 2026-04-22 |
| A Study of TAK-226 for Anemia in Japanese Patients With Lower-Risk Myelodysplastic Syndromes (NCT07319845) | Takeda | 2026-04-22 |
| A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial (NCT07443943) | University of Michigan Rogel Cancer Center | 2026-04-22 |
| Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer (NCT07558733) | Faeth Therapeutics | 2026-04-22 |
| Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder (NCT05529927) | Parnassia Addiction Research Centre | 2026-04-22 |
| Study of Aritinercept in Patients With Generalized Myasthenia Gravis (NCT07596901) | Aurinia Pharmaceuticals Inc. | 2026-04-22 |
| 5-Fluorouracil Response and Optimization STudy (The FROST Trial) (NCT07419464) | Washington University School of Medicine | 2026-04-21 |
| FAPI-PET Value for the Initial Screening of Pancreatic and Biliary Cancers (NCT07478523) | University Hospital, Bordeaux | 2026-04-21 |
| A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD) (NCT07227207) | Tessera Therapeutics, Inc. | 2026-04-21 |
| Adebrelimab Plus S-1 for Resected Cholangiocarcinoma (NCT07561775) | Xingjun Guo | 2026-04-21 |
| Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial (NCT07161726) | University of Alabama at Birmingham | 2026-04-21 |
| Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy (NCT07103746) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-04-21 |
| Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma (NCT07569068) | Ruijin Hospital | 2026-04-21 |
| Bugitinib Combined With Venetoclax and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia (NCT07563179) | Shenzhen University General Hospital | 2026-04-21 |
| JS212 Plus JS111 in EGFR-Mutant Advanced NSCLC: A Phase II Study (NCT07518160) | Shanghai Junshi Bioscience Co., Ltd. | 2026-04-21 |
| Clindamycin as an Alternative to Vancomycin in Patients Undergoing Aortic Cardiac Surgery With Extracorporeal Circulation (ECC) (NCT07267013) | Nantes University Hospital | 2026-04-21 |
| VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma (NCT07510334) | Mayo Clinic | 2026-04-21 |
| Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma (NCT07346144) | Trogenix ltd | 2026-04-21 |
| Benmelstobart Plus Anlotinib Combined With SBRT for Patients With Hepatocellular Carcinoma Failing First-Line Targeted Therapy (NCT07537777) | Nanfang Hospital, Southern Medical University | 2026-04-20 |
| Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial") (NCT07411599) | M.D. Anderson Cancer Center | 2026-04-20 |
| RE104 Safety and Efficacy Study in Generalized Anxiety Disorder (NCT07489651) | Reunion Neuroscience Inc | 2026-04-20 |
| A Study of Benmelstobart, Anlotinib, Chemotherapy and Thoracic Radiotherapy for People With Extensive-stage Small Cell Lung Cancer (NCT07538271) | Yayi He | 2026-04-20 |
| CAR-T Combined With ASCT in the Treatment of Relapsed/Refractory Large B-cell Lymphoma With High-risk Factors. (NCT07538635) | Zhejiang Cancer Hospital | 2026-04-20 |
| Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015) (NCT07486960) | Merck Sharp & Dohme LLC | 2026-04-20 |
| Neoadjuvant Iparomlimab/Tuvonralimab Plus CAPEOX Versus Iparomlimab/Tuvonralimab Plus CAPEOX and Propranolol for Locally Advanced pMMR Colon Cancer: A Prospective, Single-Center, Multi-Cohort Study (NCT07549906) | Sun Yat-sen University | 2026-04-20 |
| IBI343 in Combination Therapy for Advanced Malignant Solid Tumors (NCT07483554) | Innovent Biologics (Suzhou) Co. Ltd. | 2026-04-20 |