| Pressure Targeting During High Flow Therapy in Premature Infants (NCT07418502) | University of Texas at Austin | 2026-05-01 |
| Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas in Salvage Radiotherapy Using SBRT for Prostate Cancer to Reduce Treatment Toxicity (NCT07515651) | University Health Network, Toronto | 2026-05-01 |
| "IL-1β Blockade to Prevent Immunothrombosis in Recipients of a Pancreatic Organ" (NCT07503834) | Nantes University Hospital | 2026-05-01 |
| Neoadjuvant Radio-immunotherapy Versus Immunotherapy Alone for Locally Advanced HNSCC (NCT07554768) | Chen Chunyan | 2026-05-01 |
| Limertinib Plus Carboplatin and Etoposide for EGFR-mutant NSCLC With SCLC Transformation After EGFR-TKI Progression (NCT07001995) | Hunan Province Tumor Hospital | 2026-05-01 |
| A Single-Arm, Dose Escalation of an Intraurethral Alprostadil Paste for Erectile Dysfunction (NCT07601646) | Ryan Flannigan, MD | 2026-05-01 |
| Metformin and Alveolar Cleft (NCT07536620) | Fayoum University | 2026-05-01 |
| Seladelpar in Adult Liver Transplant Recipients With Ischemic Cholangiopathy (SELIC). (NCT07305363) | University of California, San Diego | 2026-05-01 |
| A Phase 2 Study of Bcl-2 Inhibitor Combined With Azacitidine for Newly Diagnosed Mixed Phenotype Acute Leukemia (NCT07573670) | The First Affiliated Hospital of Soochow University | 2026-05-01 |
| Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLC (NCT07405190) | Massachusetts General Hospital | 2026-05-01 |
| A Clinical Study of SCTB41 Combined With Docetaxel in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer（Phase II Study Ongoing） (NCT07609251) | Sinocelltech Ltd. | 2026-05-01 |
| Tislelizumab Plus Chemotherapy and BACE for Unresectable NSCLC (NCT07561983) | Sichuan Cancer Hospital and Research Institute | 2026-05-01 |
| This Study is Comparing Morning vs Random Scheduling of Standard of Care Pembrolizumab Checkpoint Inhibitor Immunotherapy Infusions in Patients With Metastatic Non-small Cell Lung Cancer (NCT06882174) | AHS Cancer Control Alberta | 2026-05-01 |
| Safety and Efficacy of Gene Therapy of FHL Type 3 Caused by Mutations in the Human UNC13D Gene by Transplantation of a Single Dose of Autologous CD34+ Cells Transduced ex Vivo With the UNC13D LV Vector Expressing the UNC13D cDNA (NCT06736080) | Assistance Publique - Hôpitaux de Paris | 2026-05-01 |
| Duloxetine in Inflammatory Bowel Diseases (NCT07431606) | University of Pennsylvania | 2026-05-01 |
| Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy (NCT07373535) | Kyle Greenway | 2026-05-01 |
| Short-Course Online Adaptive Radiotherapy Combined With Chemotherapy, Targeted Therapy and Immunotherapy as Total Neoadjuvant Therapy (TNT) for Locally Advanced Rectal Cancer (NCT07581626) | Chinese PLA General Hospital | 2026-05-01 |
| Absorbable Drug-Eluting Lacrimal Sac Stent for Recurrent Chronic Dacryocystitis (NCT07499791) | Beijing Tongren Hospital | 2026-05-01 |
| A Phase II Clinical Study of Utidelone and Bevacizumab With or Without Etoposide in Patients With Brain Metastases From Malignant Solid Tumors (NCT07449481) | Tianjin Medical University Cancer Institute and Hospital | 2026-05-01 |
| Defining the Ablative Dose for Y-90 TARE (NCT07586046) | Northwestern University | 2026-05-01 |
| Triamcinolone Nanocapsules After Endoscopic Nasal Surgery (NCT07714525) | Deraya University | 2026-05-01 |
| A Study to Evaluate the Efficacy and Safety of Monosialotetrahexosylganglioside Sodium Injection in Parkinson's Disease Participants With Motor Fluctuations (NCT07585565) | Qilu Pharmaceutical Co., Ltd. | 2026-05-01 |
| Evaluating Ivonescimab in PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma (NCT07565389) | National University Hospital, Singapore | 2026-05-01 |
| A Novel Aromatase Inhibitor, Leflutrozole, for Treatment of Non-Obstructive Azoospermia (NCT07571928) | Martin Blomberg Jensen | 2026-05-01 |
| Utilization of Flotufolastat 18F PET for Post-Focal Therapy Prostate Cancer Evaluation (NCT07568756) | University of California, Irvine | 2026-05-01 |
| Efficacy of Extracorporeal Shockwave Therapy on Plantar Fasciitis in Patients With Peripheral Neuropathy (NCT07587255) | National Taiwan University Hospital | 2026-05-01 |
| Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies (NCT07484906) | University of New Mexico | 2026-05-01 |
| Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors (NCT06528691) | St. Jude Children's Research Hospital | 2026-05-01 |
| Adaptive Radiotherapy for Safe Hypofractionation (NCT07516210) | Centre hospitalier de l'Université de Montréal (CHUM) | 2026-05-01 |
| PollenVax Subcutaneous Immunotherapy for Mugwort Pollen-Induced Allergic Rhinitis (NCT07563439) | Kazakh National Agrarian University | 2026-05-01 |
| IO Vancomycin Spine (NCT06748144) | The Methodist Hospital Research Institute | 2026-05-01 |
| Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis (NCT07580716) | Enlivex Therapeutics Ltd. | 2026-05-01 |
| Efficacy and Safety of QL1706 Combined With Nab-paclitaxel and Cisplatin as 1st Line Therapy for Advanced or Metastatic Esophageal Squamous Cell Carcinoma (NCT07533305) | The First Affiliated Hospital of Henan University of Science and Technology | 2026-05-01 |
| Microwave Ablation Plus Tislelizumab and Docetaxel in Advanced NSCLC After First-Line Immunotherapy Failure (NCT07528274) | Tianjin Medical University Cancer Institute and Hospital | 2026-05-01 |
| A Clinical Trial Evaluating the Safety and Efficacy of AP1189 Versus Placebo as an add-on to Standard of Care in Participants With Respiratory Insufficiency Expected to be Caused by Infection With Respiratory Viruses (NCT07633288) | SynAct Pharma Aps | 2026-05-01 |
| Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study (NCT07304440) | Adia Med of Winter Park LLC | 2026-05-01 |
| Low-Dose ATG/PTCy Plus Ivarmacitinib for aGVHD Prevention in Haplo-PBSCT From Parous Female Donors (NCT07570745) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2026-05-01 |
| Vaccination Response Modulation With a Targeted Rapamycin Protocol Study (NCT07587801) | Central Adelaide Local Health Network Incorporated | 2026-05-01 |
| An Phase I/IIa Clinical Study to Evaluate the Safety/Tolerability, Pharmacokinetics and Preliminary Efficacy of INB301 Injection in Patients With Cancer Cachexia (NCT07584057) | Yunnan Baiyao Group Co., Ltd. | 2026-05-01 |
| A Multicenter, Phase Ib/II Clinical Trial to Evaluate the Efficacy and Safety of Concurrent Combination Therapy of S-531011 Plus Fruquintinib or S-531011 Plus Fruquintinib Plus Pembrolizumab in Patients With MSS/pMMR Colorectal Cancer (NCT07591597) | National Cancer Center Hospital East | 2026-05-01 |
| Beta-3 Enhanced Autonomic Therapy for POTS (NCT07585513) | Cedars-Sinai Medical Center | 2026-05-01 |
| Neoadjuvant SHR-A1811 Combined With Pertuzumab in HER2-Positive Breast Cancer: An Exploratory Clinical Study. (NCT07528898) | Hebei Medical University Fourth Hospital | 2026-05-01 |
| TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell Lymphoma (NCT07502872) | Brown University | 2026-05-01 |
| Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section (NCT07550413) | Pak Emirates Military Hospital | 2026-05-01 |
| Disitamab Vedotin Plus Radiotherapy for Adjuvant Treatment of HER2-Expressing Cisplatin-Ineligible Upper Tract Urothelial Carcinoma (NCT07498907) | Peking University First Hospital | 2026-05-01 |
| Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies (NCT07520006) | Nurix Therapeutics, Inc. | 2026-05-01 |
| Neoadjuvant Pucotenlimab Combined With Lenvatinib and Temozolomide in Resectable Stage IIB/III Acral Melanoma (NCT07501104) | Shanghai Zhongshan Hospital | 2026-05-01 |
| Microbiome-guided Prophylaxis to Reduce Ventilator-Associated Pneumonia in Intensive Care Units: A Pilot Randomized Controlled Trial (NCT07463339) | University of Calgary | 2026-05-01 |
| Partner4Exercise Randomized Controlled Trial (NCT07408128) | McMaster University | 2026-05-01 |
| Immunotherapy With Baricitinib and Sirolimus, Alone and in Combination, for the Control of HIV-1 Replication After Antiretroviral Treatment Interruption (NCT07081763) | ANRS, Emerging Infectious Diseases | 2026-05-01 |
| Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy (NCT07576335) | Surgical Outcomes Research Centre (SOuRCe) | 2026-05-01 |
| The Safety and Efficacy of XytriX (Umbilical Cord-Derived Mesenchymal Stem Cells) in the Treatment of Knee Osteoarthritis (NCT07487766) | TricelX Inc. | 2026-05-01 |
| Efficacy of Cannabidiol in the Management of Self-injuries in Children and Adolescents With Severe Neurodevelopmental Disorders. (NCT07564245) | Assistance Publique - Hôpitaux de Paris | 2026-05-01 |
| Role of UC-MSC and CM to Inhibit Vision Loss in Retinitis Pigmentosa Phase I/II (NCT05909488) | PT. Prodia Stem Cell Indonesia | 2026-05-01 |
| Patients Between the Ages of 12 Months to 21 Years With Newly-Diagnosed High-Risk Neuroblastoma Will Receive Children's Oncology Group (COG) Type Recommended Therapy With the Addition of Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) to Induction Cycles 1-5 (NCT07537400) | Shaare Zedek Medical Center | 2026-05-01 |
| Behavioural Intervention to Decrease Exposure to Emerging Chemical Pollutants (NCT07465315) | Universidad de Granada | 2026-05-01 |
| Safety and Efficacy of scAAV9/AGA Gene Therapy in Participants With Aspartylglucosaminuria (AGU) (NCT07530796) | Rare Trait Hope | 2026-05-01 |
| Optimization of Dynamic Neoadjuvant Therapy Strategies for HER2-Positive Breast Cancer Based on HER2-PET/CT Molecular Imaging (NCT07527806) | Peking University Cancer Hospital & Institute | 2026-05-01 |
| Focused Ultrasound Blood-Brain Barrier Opening in Pontine Diffuse Midline Glioma to Enhance Temozolomide Therapy: Pilot Feasibility Study (FIDES) (NCT07562971) | UMC Utrecht | 2026-05-01 |
| Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket Trial (NCT06381661) | Assistance Publique - Hôpitaux de Paris | 2026-05-01 |
| Exosome Therapy for Male Androgenetic Alopecia (NCT07693244) | Zhang Han | 2026-04-30 |
| A Study Of SHR-1918 In Participants With Hypercholesterolemia With Inadequate Lipid Control on Statins Plus PCSK9 Inhibitors (NCT07404553) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2026-04-30 |
| Phase II Study of Ultrasound and ctDNA Guided Neoadjuvant Systemic Therapy for Patients With HER2-positive Early Breast Cancer (UC HER Trial) (NCT07565324) | National Taiwan University Hospital | 2026-04-30 |
| Neoadjuvant Treatment of Fulzerasib Plus Cetuximab N01 in KRAS G12C Mutated Locally Advanced Colorectal Cancer With or Without Resectable Metastases (NCT07581912) | Zhejiang University | 2026-04-30 |
| A Multicentre, Randomised, Double-blind, Positive-control Clinical Trial Evaluating Dihydroartemisinin Tablets for the Treatment of Discoid Lupus Erythematosus (NCT07557927) | Kunming Pharmaceuticals, Inc. | 2026-04-30 |
| Pragmatic Study to Optimize Neoadjuvant Treatment and Surgical De-escalation in HR+/HER2- Early Breast Cancer Using Oncotype DX and Abemaciclib (NCT07428018) | Mario Negri Institute for Pharmacological Research | 2026-04-30 |
| A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC288 in the Treatment of Solid Tumors (NCT07537881) | RemeGen Co., Ltd. | 2026-04-30 |
| CASCADE: Testing for Safety and Immune Effects of PDS0101, an Anti-HPV Therapy, Among People Living With HIV (NCT07090174) | University of California, San Diego | 2026-04-30 |
| Study of the Safety and Efficacy of DS010 in Patients With Cancer Cachexia (NCT07530666) | Dartsbio Pharmaceuticals Ltd. | 2026-04-30 |
| Phase IIb Clinical Study to Assess the Efficacy and Safety of GenSci120 Injection in Patients With Moderately to Severely Active RA Who Have an Inadequate Response to at Least One DMARD (NCT07423533) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2026-04-30 |
| Strengthening HPV Immunization Through EPI Leveraged Delivery (NCT07377656) | International Vaccine Institute | 2026-04-30 |
| Sequential FOLFOX-HAIC-TACE Plus Sintilimab-Bevacizumab Neoadjuvant Therapy Versus Direct Resection in Resectable High-Risk Recurrence Hepatocellular Carcinoma (NCT07522411) | BinYong Liang | 2026-04-30 |
| Becotatug Vedotin ± Anti-PD-1 in Pretreated Advanced ESCC (NCT07403136) | Fudan University | 2026-04-30 |
| JY016 Injection in Patients With Advanced Solid Tumors Expressing EGFR (NCT07510841) | Biotech Pharmaceutical Co., Ltd. | 2026-04-30 |
| Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease (NCT07553338) | Weill Medical College of Cornell University | 2026-04-30 |
| Intranasal Insulin to Prevent Intensive Care Unit Delirium (NCT07532577) | Radboud University Medical Center | 2026-04-30 |
| A Phase II Clinical Trial of the Safety and Efficacy of SAL056 at Different Doses and Dosing Regimens (NCT07579936) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2026-04-30 |
| Tislelizumab Plus Zeprumetostat for Relapsed or Refractory NK/T-Cell Lymphoma (NCT07502768) | Rong Tao | 2026-04-30 |
| Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined. (NCT07546942) | Black Tie Medical, Inc. | 2026-04-30 |
| Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities (NCT07572396) | Amplexd Therapeutics, Inc. | 2026-04-30 |
| 18F-mFBG Cardiac Uptake With Lewy Body Dementia (NCT07176286) | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 2026-04-30 |
| A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F) (NCT07286149) | Merck Sharp & Dohme LLC | 2026-04-30 |
| A Phase II Clinical Study of SHR-A1904 Monotherapy in Second-Line or Later Treatment of Advanced Neuroendocrine Carcinoma (NCT07520357) | Beijing GoBroad Hospital | 2026-04-30 |
| A Phase Ⅰb/Ⅱa Clinical Study of IMC-003 Injection for the Treatment of Pulmonary Arterial Hypertension Receiving Background Therapy. (NCT07593027) | ImmuneCare Biopharmaceuticals (Shanghai) Co., Ltd. | 2026-04-30 |
| Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy (NCT07456852) | Mayo Clinic | 2026-04-30 |
| Chidamide Combination With R-mini CHOP Followed by Chidamide+CD20 Maintenance in Elderly Newly Diagnosed MYC/BCL2+ DLBCL (NCT07493148) | Ou Bai, MD/PHD | 2026-04-30 |
| A Study of the Effectiveness and Safety of JS1-1-01 Tablet in Patients With Moderate to Severe Depression (NCT07485595) | Tasly Pharmaceutical Group Co., Ltd | 2026-04-30 |
| A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma (NCT07490301) | AbbVie | 2026-04-30 |
| Horizon Two: HR NDMM (MMRC-100) (NCT07053436) | Multiple Myeloma Research Consortium | 2026-04-30 |
| Intranasal Dexmedetomidine for Acute Anxiety State in Adults (NCT07550881) | Tongji University | 2026-04-30 |
| Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder (NCT07523633) | Anders Fink-Jensen, MD, DMSci | 2026-04-30 |
| Mast Cell Treatment in Post-tick Bite Illness (PTBI) (NCT07526558) | University of North Carolina, Chapel Hill | 2026-04-30 |
| The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related Toxicities (NCT07381634) | First Affiliated Hospital of Wenzhou Medical University | 2026-04-30 |
| Platform Trial Assessing Uptake, Safety and Efficacy of Theranostic Agents in Solid Tumors With Active Brain Metastases (NCT07178938) | MedSIR | 2026-04-30 |
| Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy (NCT07502508) | Biomea Fusion Inc. | 2026-04-30 |
| A Study in Adults With Desmoid Tumors (NCT07541430) | Elpiscience (Suzhou) Biopharma, Ltd. | 2026-04-30 |
| FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer (NCT07446322) | Oncolytics Biotech | 2026-04-30 |
| Neoadjuvant Tislelizumab-Lenvatinib vs Surgery Alone in Stage Ia HCC With Narrow Margin (NCT07518706) | Tianjin Medical University Cancer Institute and Hospital | 2026-04-30 |
| SHR-A1811 + AK112 in HER2-Altered Advanced/Metastatic NSCLC (NCT07489703) | Sun Yat-sen University | 2026-04-30 |
| A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States (NCT07554521) | BeOne Medicines | 2026-04-30 |