| Effect of Tranexamic Acid and Calcium Dobesilate for Bleeding of Endometrial Origin (NCT06707051) | District Headquarters Teaching Hospital Sahiwal | 2022-01-01 |
| Radomised Phase II Study of MTL-CEBPA Plus Sorafenib or Sorafenib Alone (NCT04710641) | Mina Alpha Limited | 2022-01-01 |
| Study on the Biomarker of First-line Immunotherapy Combined With Chemotherapy in Advanced Esophageal Cancer (NCT05174156) | Sixth Affiliated Hospital, Sun Yat-sen University | 2022-01-01 |
| Impact of CBD-Rich Oil on Aversive Memory Reconsolidation (NCT04726475) | University of Texas at Austin | 2022-01-01 |
| Blincyto Amgen Acrotech BioPharma PH2 Blincyto Marqibo R/R Philadelphi CD19+ ALL (NCT04448834) | Dorothy Sipkins, MD, PhD | 2022-01-01 |
| Efficacy of SMOF Lipid in the Management of Acute Poisoning With Clozapine (NCT06413589) | Alexandria University | 2022-01-01 |
| FITMI - First In Treating Male Infertility (NCT05212337) | Martin Blomberg Jensen | 2022-01-01 |
| Safety Analysis of Intravenous Rapid Infusion of Obinutuzumab in Patients With B-cell Non-Hodgkin's Lymphoma in China (NCT05510219) | The First Affiliated Hospital with Nanjing Medical University | 2022-01-01 |
| Almonertinib Plus Microwave Ablation in Advanced Non-small Cell Lung Cancer (NCT04755738) | Qianfoshan Hospital | 2022-01-01 |
| Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors (NCT05117138) | Beijing Immunochina Medical Science & Technology Co., Ltd. | 2022-01-01 |
| Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer (NCT05450029) | Yanhong Deng | 2022-01-01 |
| Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency (NCT05397665) | Applied Therapeutics, Inc. | 2022-01-01 |
| SIRT-1 Antagonism for Endometrial Receptivity (NCT04184323) | Wake Forest University Health Sciences | 2022-01-01 |
| Concurrent Chemoradiotherapy Followed by PD-1 Inhibitor in Advanced Cervical Cancer (NCT06391190) | RenJi Hospital | 2022-01-01 |
| Phage Therapy for the Prevention and Treatment of Pressure Ulcers. (NCT04815798) | Precisio Biotix Therapeutics, Inc. | 2022-01-01 |
| Topical CBD for Musculoskeletal Pain (NCT05170451) | University of Virginia | 2022-01-01 |
| Anlotinib Plus PD-1 Inhibitor as 2nd-line Threapy in Patients With Metastatic Pancreatic Cancer (NCT05218629) | Qingdao Central Hospital | 2022-01-01 |
| Recombinant Humanized Anti-CD47/PD-1 Bifunctional Antibody HX009 in Patients With Relapsed/Refractory Lymphoma (NCT05189093) | Hangzhou Hanx Biopharmaceuticals, Ltd. | 2021-12-31 |
| IBI376 Plus Rituximab in Patients With Untreated Indolent Lymphoma. (NCT05073250) | Chinese PLA General Hospital | 2021-12-31 |
| A Study To Evaluate the Safety, Tolerance, Pharmacokinetics/Pharmacodynamics and Efficacy of SYHA1402 Tablets For the Treatment of Patients With Diabetic Peripheral Neuropathy in China (NCT05116111) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-12-31 |
| CO Monitoring for Tobacco Cessation in Quitlines (NCT05327660) | Consumer Wellness Solutions | 2021-12-31 |
| 89Zr-Trastuzumab PET/CT in Subjects With Previously Treated HER2-Positive Solid Tumors Scheduled to Receive Treatment With MT-5111 (NCT04757090) | Washington University School of Medicine | 2021-12-31 |
| Senaparib in mCRPC Patients With Homologous Recombination Repair Gene Alterations After Docetaxel Treatment (NCT04822961) | Impact Therapeutics, Inc. | 2021-12-31 |
| Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active Nr-axSpA (NCT05242588) | Shanghai Junshi Bioscience Co., Ltd. | 2021-12-31 |
| LS301 Uptake in Tumors of Patients Undergoing Liver, Pancreas, or Gastric Surgery (NCT04105062) | Washington University School of Medicine | 2021-12-31 |
| A Study to Investigate Vamikibart (RO7200220) in Diabetic Macular Edema (NCT05151731) | Hoffmann-La Roche | 2021-12-31 |
| A Multicenter, Randomized Controlled, Phase II Clinical Study of First-line Chemotherapy and Camrelizumab With or Without Radiotherapy in the Treatment of Oligometastatic Esophageal Cancer (NCT05183958) | Zhejiang Cancer Hospital | 2021-12-31 |
| Clinical Trial of Mesenchymal Stem Cells in the Treatment of Severe Acute Kidney Injury (NCT04194671) | Chinese PLA General Hospital | 2021-12-31 |
| Study to Evaluate the Safety and Efficacy of IM19 CAR-T Cells in Patients With Relapsed and Refractory (R/R) Mantle Cell Lymphoma (NCT05155215) | Beijing Immunochina Medical Science & Technology Co., Ltd. | 2021-12-31 |
| Camrelizumab Plus Pyrotinib Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (NCT05111444) | Fudan University | 2021-12-31 |
| Exploring the Safety and Effectiveness of Toripalimab Combined With Neoadjuvant Radiotherapy and Chemotherapy in the Locally Advanced Esophageal Squamous Cell Carcinoma (NCT04888403) | The First Affiliated Hospital of Zhengzhou University | 2021-12-31 |
| Anti-FLT3 CAR T-cell Therapy in FLT3 Positive Relapsed/Refractory Acute Myeloid Leukemia (NCT05023707) | The First Affiliated Hospital of Soochow University | 2021-12-31 |
| Safety & Immunogenicity of Booster SARS-CoV-2 Vaccine (Vero Cell) (NCT05172193) | PT. Kimia Farma (Persero) Tbk | 2021-12-31 |
| Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors (NCT04921189) | Asan Medical Center | 2021-12-31 |
| A Safety, Tolerability, and Efficacy Study of IBI314 in Patients With Mild to Moderate COVID-19 (NCT05172141) | Innovent Biologics (Suzhou) Co. Ltd. | 2021-12-31 |
| P2 Clinical Efficacy & Safety Study of V-111 Monotherapy & Sacituzumab Govitecan-hziy/V-111 Combo Therapy for mTNBC . (NCT05008510) | Veru Inc. | 2021-12-30 |
| A Phase 2, Open-Label Study of ABSK-011 Combined Atezolizumab or SOC in HCC Patients (NCT05441475) | Abbisko Therapeutics Co, Ltd | 2021-12-30 |
| Angiotensin-(1,7) Treatment in COVID-19: the ATCO Trial (NCT04332666) | Erasme University Hospital | 2021-12-30 |
| A Phase 2 Clinical Study of Evaluation of Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection (609A) Combined With Doxorubicin Hydrochloride in the Treatment of Metastatic/Unresectable Non-specific Soft Tissue Sarcoma (NCT05138146) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2021-12-30 |
| A Study to Evaluate Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx) in Patients With Polycythemia Vera (NCT05143957) | Ionis Pharmaceuticals, Inc. | 2021-12-30 |
| Evaluation of the Safety and Efficacy of Hemophilia B Gene Therapy Drug (NCT05203679) | Shanghai Xinzhi BioMed Co., Ltd. | 2021-12-30 |
| Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects (NCT05256017) | Drugs for Neglected Diseases | 2021-12-30 |
| A Study of Single Drug TJ011133 and Toripalimab Combine Treatment for Advanced Solid Tumor (NCT05148533) | TJ Biopharma Co., Ltd. | 2021-12-30 |
| Human COVID-19 Immunoglobulin (COVID-HIG) Therapy for COVID-19 Patients (NCT05173441) | Sinopharm Wuhan Plasma-derived Biotherapies Co., Ltd. | 2021-12-30 |
| Efficacy of Adding Lidocaine 10% to Phenol in Ultrasound Guided Superior Hypogastric Plexus Neurolysis in The Management of Pelvic Cancer Pain (NCT05145972) | Mansoura University | 2021-12-30 |
| Study to Assess the Efficacy and Safety of Orismilast in Psoriasis (NCT05190419) | UNION therapeutics | 2021-12-30 |
| A Phase II Study of TACE Plus PD-1 Antibody in the Locally Advanced Stomach Adenocarcinoma (NCT04799548) | Shanghai Zhongshan Hospital | 2021-12-30 |
| Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies (NCT05054725) | Revolution Medicines, Inc. | 2021-12-30 |
| GVHD Prophylaxis by Addition of CD20 Monoclonal Antibody to the Conditioning Regimen in SAA With Treatment of Allo-HSCT (NCT05510505) | The First Affiliated Hospital of Soochow University | 2021-12-30 |
| A Study to Evaluate the Safety and Tolerance of SYHX1903 in Patients With Relapsed/Refractory Hematologic Malignancies (NCT05055791) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-12-29 |
| Neoadjuvant Immunochemotherapy in Locally Advanced Esophagogastric Junction Adenocarcinoma (NCT05170503) | Sun Yat-sen University | 2021-12-29 |
| A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16) (NCT04945460) | Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA | 2021-12-29 |
| SCI-110 for Alzheimer Disease and Agitation (NCT05239390) | The Israeli Medical Center for Alzheimer's | 2021-12-29 |
| Treatment of Selinexor in Combination With Clarithromycin, Pomalidomide and Dexamethasone for Relapsed Refractory Multiple Myeloma Patients (NCT04843579) | Weill Medical College of Cornell University | 2021-12-29 |
| Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study) (NCT04947319) | Ono Pharmaceutical Co., Ltd. | 2021-12-29 |
| ZF2001 Booster Immunization Clinical Trials of 12 Months After the Completion of Basic Immunization (NCT05198102) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2021-12-29 |
| Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients (NCT05077969) | Leidos Life Sciences | 2021-12-29 |
| A Study of JZP150 in Adults With Posttraumatic Stress Disorder (NCT05178316) | Jazz Pharmaceuticals | 2021-12-29 |
| Mix and Match Heterologous Prime-Boost Study Using Approved COVID-19 Vaccines (NCT04998240) | International Vaccine Institute | 2021-12-29 |
| A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies (NCT05199272) | 23andMe, Inc. | 2021-12-29 |
| LEAP-CT for Treatment of COVID-19 Patients (Master Protocol) (NCT05077332) | Leidos Life Sciences | 2021-12-29 |
| ATI-450 vs Placebo in Participants With Moderate to Severe Hidradenitis Suppurativa (HS) (NCT05216224) | Aclaris Therapeutics, Inc. | 2021-12-29 |
| A Study to Evaluate the Safety and Pharmacokinetics of Ataluren in Participants From ≥6 Months to <2 Years of Age With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) (NCT04336826) | PTC Therapeutics | 2021-12-29 |
| A Phase II Randomized Study of Gemcitabine and Nab-paclitaxel in Combination With S- 1/LV (GASL) or Oxaliplatin (GAP) as First-line Treatment for Metastatic Pancreatic Cancer (NCT05026905) | National Health Research Institutes, Taiwan | 2021-12-28 |
| A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With Heart Failure With Reduced Ejection Fraction (NCT05139615) | Pfizer | 2021-12-28 |
| Adjuvant Targeted-therapy for Patients With Resected High-risk EGFR-mutant Stage IB-IIA Non-small Cell Lung Carcinoma (NCT05165355) | Tongji University | 2021-12-28 |
| Study of Tesomet With Open-label Extension in Subjects With Prader-Willi Syndrome (NCT05198362) | Saniona | 2021-12-28 |
| A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults (NCT05164094) | ModernaTX, Inc. | 2021-12-28 |
| Carfilzomib and Belatacept for Desensitization (NCT05017545) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-12-28 |
| Osimertinib Plus Chemotherapy vs Osimertinib in EGFRm NSCLC With Persistence Week-3 ctDNA EGFRm After 1L Osimertinib (NCT04769388) | Beijing Cancer Prevention & Treatment Society | 2021-12-28 |
| A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy (NCT05139602) | AbbVie | 2021-12-28 |
| First-line Treatment of PCNSL With the Combination of Orelabrutinib, Rituximab, and Methotrexate (ORM Regimen) (NCT06454266) | Ningbo No. 1 Hospital | 2021-12-28 |
| A Study to Evaluate the Safety and Efficacy of Oral APL-1202 in Combination With Tislelizumab Compared to Tislelizumab Alone as Neoadjuvant Therapy in Patients With Muscle Invasive Bladder Cancer (NCT04813107) | Jiangsu Yahong Meditech Co., Ltd aka Asieris | 2021-12-28 |
| Urea for Chronic Hyponatremia (NCT04588207) | Helbert Rondon Berrios, MD, MS | 2021-12-28 |
| PROPER Trial of Pain and Inflammation After Knee Arthroscopy (NCT05149287) | Austin V Stone | 2021-12-28 |
| Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL (NCT05147467) | Ascentage Pharma Group Inc. | 2021-12-28 |
| A Study of Xiongdan Wan Treating Depression (NCT05136365) | Shanghai Mental Health Center | 2021-12-28 |
| A Phase II Study to Evaluate the Efficacy and Safety of MBA-P01 in Subjects With Moderate to Severe Glabellar Lines (NCT05217355) | Medytox Korea | 2021-12-28 |
| INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa (NCT04908215) | InMed Pharmaceuticals Inc. | 2021-12-28 |
| Lomecel-B Effects on Alzheimer's Disease (NCT05233774) | Longeveron Inc. | 2021-12-28 |
| Norovirus Challenge Study (NCT05212168) | Vaxart | 2021-12-27 |
| Inhaled Recombinant Non-immunogenic Staphylokinase vs Placebo in Patients With COVID-19 - FORRIF Trial (NCT05135546) | Supergene, LLC | 2021-12-27 |
| Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone (NCT04676802) | Stanford University | 2021-12-27 |
| Biased Opioid Agonists for Treatment of Opioid Withdrawal in OUD (NCT04316559) | National Institute on Drug Abuse (NIDA) | 2021-12-27 |
| Safety of Flonoltinib Maleate Tablets for the Treatment of Patients With Myeloproliferative (NCT05153343) | Chengdu Zenitar Biomedical Technology Co., Ltd | 2021-12-27 |
| Hepatic Artery Infusion Chemotherapy Plus Donafenib in Patients With Hepatocellular Carcinoma After Surgery (NCT04962958) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2021-12-27 |
| Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy (NCT04359784) | Fred Hutchinson Cancer Center | 2021-12-27 |
| Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia (NCT04925479) | Novartis Pharmaceuticals | 2021-12-27 |
| Reducing Abundance of Human Papilloma Virus in Women by Taking Probiotic (NCT05316064) | Universiti Sains Malaysia | 2021-12-27 |
| Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases (NCT05026983) | M.D. Anderson Cancer Center | 2021-12-27 |
| Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable: a Multi-center Study (NCT05418309) | Tianjin Medical University Second Hospital | 2021-12-27 |
| Lenvatinib+Letrozole Versus Fulvestrant in Metastatic ER+/HER2- Breast Cancer, Post Progression on Al + CDK4/6 Inhibitor (NCT05181033) | National University Hospital, Singapore | 2021-12-27 |
| Autologous BMMNCs Combined With Educational Intervention for ASD (NCT05307536) | Vinmec Research Institute of Stem Cell and Gene Technology | 2021-12-26 |
| Continuation Study of Long-term Safety, Tolerability, Pharmacokinetics and Efficacy of Recifercept in Achondroplasia (NCT05116046) | Pfizer | 2021-12-24 |
| The Neoadjuvant Treatment of Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma. (NCT05170542) | Peking Union Medical College Hospital | 2021-12-24 |
| Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease (NCT04939116) | Angion Biomedica Corp | 2021-12-24 |
| Regorafenib After Progression on Atezolizumab Plus Bevacizumab in Advanced HCC (NCT05134532) | CHA University | 2021-12-24 |
| A Study of Bevacizumab Combined With Fluzoparib/Chemotherapy or Fluzoparib in the Treatment of Ovarian Cancer (NCT05170594) | The Second Affiliated Hospital of Shandong First Medical University | 2021-12-24 |
| Neoadjuvant HAIC of TACE Plus Donafenib in BCLC B Stage HCC: a Multi-center Randomized Controlled Trial. (NCT05171166) | Peking University | 2021-12-24 |
| Pioglitazone Therapy Targeting Fatigue in Breast Cancer (NCT05013255) | West Virginia University | 2021-12-23 |