| Efficacy of the Anti-Bet v 1 Monoclonal Antibodies (Given Subcutaneously) to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen in Adult Participants (NCT05430919) | Regeneron Pharmaceuticals | 2022-08-15 |
| Treatment of Patients With Chronic Hepatitis B With Hepatitis B Immunoglobulins (NCT05345990) | Hannover Medical School | 2022-08-15 |
| A Study of Multiple Doses of RO7247669 in Participants With Previously Untreated Unresectable or Metastatic Melanoma (NCT05419388) | Hoffmann-La Roche | 2022-08-15 |
| Targeting the Nine Hallmarks of Aging on DNA Methylation (NCT05535608) | TruDiagnostic | 2022-08-15 |
| A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma (NCT05249101) | CG Pharmaceuticals, Inc | 2022-08-15 |
| PD-1 Inhibitors With or Without Radiation in Advanced Melanoma (NCT05498805) | Fudan University | 2022-08-15 |
| ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML) (NCT05358808) | TC Biopharm | 2022-08-15 |
| Safety of Administering Isoniazid to SLE Patients to Prevent TB (NCT06618573) | Universitas Padjadjaran | 2022-08-15 |
| A Study to Assess Safety of ABBV-916 and How Intravenous ABBV-916 Moves Through Body and Affects Brain Amyloid Plaque Clearance in Adult Participants (Aged 50-90 Years) With Early Alzheimer's Disease (NCT05291234) | AbbVie | 2022-08-15 |
| Fluzoparib Combined With Bevacizumab in PSROC Previously Treated With PARPi (NCT05551208) | Chongqing University Cancer Hospital | 2022-08-15 |
| A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors (NCT05377996) | Day One Biopharmaceuticals, Inc. | 2022-08-15 |
| Smart Ankle-Foot Orthosis to Improve Stroke Outcomes: Smart AFO (NCT05619484) | Orthocare Innovations, LLC | 2022-08-15 |
| Understanding Everyday Stress (NCT05502575) | Penn State University | 2022-08-15 |
| Phase Ib/II Study of SHR-8068 Injection in the Treatment of Advanced Non-small Cell Lung Cancer (NCT05416775) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2022-08-15 |
| Combination of Curcumin and Berberine Therapy in the Treatment of Post Acute Diverticulitis (SUDD) (NCT05596214) | Dr. Adi Lahat | 2022-08-14 |
| The Effect of Erythropoietin in the Treatment of Scleral Necrosis (NCT05476042) | Shahid Beheshti University of Medical Sciences | 2022-08-14 |
| A Study of PM8002 Injection in Combination With Standard Chemotherapy as First Line Therapy in MPM (NCT05918107) | Biotheus Inc. | 2022-08-13 |
| Trial to Evaluate the Safety, Tolerability, and Immunogenicity of A Multivalent Group B Streptococcus Vaccine When Administered Concomitantly With Tdap in Healthy Nonpregnant Women (NCT04766086) | Pfizer | 2022-08-12 |
| Dietary Counselling Plus Omega-3 Supplementation in the Treatment of Generalized Anxiety Disorder (NCT05573672) | The Canadian College of Naturopathic Medicine | 2022-08-12 |
| A Phase 2 Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPG (NCT05123534) | SonALAsense, Inc. | 2022-08-12 |
| Use of Botulinum Toxin in the Treatment of Androgenic Alopecia (NCT05456087) | Zel Skin and Laser Specialists | 2022-08-12 |
| Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications (NCT05104723) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-08-12 |
| Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping (NCT05524883) | Dyne Therapeutics | 2022-08-12 |
| A Randomised, Multi-centre, Double-blind, Phase 3 Study to Observe the Effectiveness, Safety and Tolerability of Molnupiravir Compared to Placebo Administered Orally to High-risk Adult Outpatients With Mild COVID-19 Receiving Local Standard of Care in South Africa (NCT05459532) | University of Witwatersrand, South Africa | 2022-08-12 |
| Safety, Tolerability and Prophylactic Antiviral Activity of Neumifil Against Influenza Via a Human Viral Challenge Model (NCT05507567) | Pneumagen Ltd. | 2022-08-12 |
| Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout (NCT05253833) | Arthrosi Therapeutics | 2022-08-12 |
| Efficacy and Safety of Anti-PD-1/PD-L1 Treatment +/- UV1 Vaccination in Patients With Non-small Cell Lung Cancer (NCT05344209) | Vestre Viken Hospital Trust | 2022-08-12 |
| A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma (NCT05421663) | Janssen Research & Development, LLC | 2022-08-12 |
| FMT Combined With Immune Checkpoint Inhibitor and TKI in the Treatment of CRC Patients With Advanced Stage (NCT05279677) | Chinese Academy of Medical Sciences | 2022-08-12 |
| A Trial of Camrelizumab for Injection in Combination With Famitinib Malate Capsule and Paclitaxel For Injection(Albumin Bound) in Advanced Solid Tumors of Patients (NCT05214976) | Jiangsu HengRui Medicine Co., Ltd. | 2022-08-12 |
| Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression (NCT05339074) | Joshua Rosenblat | 2022-08-11 |
| Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery (NCT05111574) | National Cancer Institute (NCI) | 2022-08-11 |
| A Single-arm, Multicenter, Prospective Clinical Study of Mitoxantrone Liposome Combined With Chidamide and Azacitidine in the Treatment of Relapsed and Refractory Peripheral T-cell Lymphoma (NCT05495100) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-08-11 |
| A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (NCT05571319) | University of Stellenbosch | 2022-08-11 |
| Rehabilitation of Airway Protection in Parkinson's Disease (NCT05700825) | Teachers College, Columbia University | 2022-08-11 |
| The Influence of Tramadol on Opioid-induced Bowel Dysfunction (NCT06385561) | Asbjørn Mohr Drewes | 2022-08-11 |
| A Study of Ceralasertib Monotherapy and Ceralasertib Plus Durvalumab in Patients With Melanoma and Resistance to PD-(L)1 Inhibition (NCT05061134) | AstraZeneca | 2022-08-11 |
| Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for Treatment of Newly Diagnosed Multiple Myeloma, IDEAL Study (NCT05392946) | Mayo Clinic | 2022-08-11 |
| A Study to Evaluate the Efficacy and Safety of HR18042 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery. (NCT05470075) | Jiangsu HengRui Medicine Co., Ltd. | 2022-08-11 |
| Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan (NCT05194111) | Virginia Commonwealth University | 2022-08-11 |
| Safety, Pharmacokinetics and Efficacy of CT-707, Toripalimab and Gemcitabine in Advanced Pancreatic Cancer (NCT05580445) | Shouyao Holdings (Beijing) Co. LTD | 2022-08-11 |
| Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study) (NCT05431270) | Phanes Therapeutics | 2022-08-11 |
| A Study to Evaluate the Safety and Efficacy of LT3001 Drug Product in Subjects AIS Undergoing EVT (NCT05198323) | Lumosa Therapeutics Co., Ltd. | 2022-08-11 |
| Dalpiciclib Plus Letrozole and Capecitabine (NCT05469750) | Fujian Medical University Union Hospital | 2022-08-10 |
| HPV16 E6 TCR T Cells for Cervical Carcinoma (NCT05357027) | TCRCure Biopharma Ltd. | 2022-08-10 |
| Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V (NCT05268289) | Novartis Pharmaceuticals | 2022-08-10 |
| Immuno-PRISM (PRecision Intervention Smoldering Myeloma) (NCT05469893) | Irene Ghobrial, MD | 2022-08-10 |
| Phase II of Neoadjuvant and Adjuvant Capmatinib in NSCLC (NCT04926831) | Novartis Pharmaceuticals | 2022-08-10 |
| The Impact of Ibutamoren on Nonalcoholic Fatty Liver Disease (NCT05364684) | Massachusetts General Hospital | 2022-08-10 |
| A Single-Arm Phase II Exploratory Clinical Study of Pemigatinib in the Treatment of Advanced Gastrointestinal Cancer (Excluding Biliary Tract Cancer) Patients With FGFR Alterations Who Have Failed Standard Therapy (NCT05559775) | Zhejiang Cancer Hospital | 2022-08-10 |
| A Study of GNC-038, a Tetra-specific Antibody, in Participants With R/R Diffuse Large B-cell Lymphoma (DLBCL) (NCT05192486) | Sichuan Baili Pharmaceutical Co., Ltd. | 2022-08-10 |
| Pyridostigmine for the Treatment of Constipation in Parkinson Disease (NCT05603715) | University of Vermont Medical Center | 2022-08-10 |
| A Study to Find the Best Dose of ASP5354 to Show Lymph Nodes in People With Breast Cancer or Melanoma During Surgery (NCT05457842) | Astellas Pharma Inc | 2022-08-10 |
| Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke (NCT04834388) | Radboud University Medical Center | 2022-08-10 |
| Evaluation of the Presence of SENS-401 in the Perilymph (NCT05258773) | Sensorion | 2022-08-10 |
| Efficacy and Safety of Fospropofol Disodium Versus Propofol for Sedation in Mechanically Ventilated ICU Patients (NCT05491278) | Xiaobo Yang, MD | 2022-08-10 |
| Safety and Efficacy of Fruquintinib+FOLFIRI in RAS-mutated Metastatic Colorectal Cancer (NCT05522738) | Chinese PLA General Hospital | 2022-08-10 |
| Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL) (NCT04871529) | SWOG Cancer Research Network | 2022-08-10 |
| A Study of Belzutifan (MK-6482) in Combination With Palbociclib Versus Belzutifan Monotherapy in Participants With Advanced Renal Cell Carcinoma (MK-6482-024/LITESPARK-024) (NCT05468697) | Merck Sharp & Dohme LLC | 2022-08-10 |
| A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD) (NCT05390840) | Theratocular Biotek Co. | 2022-08-09 |
| Transcranial Photobiomodulation for Executive Function in Bipolar Disorder (NCT05408637) | Paolo Cassano | 2022-08-09 |
| Pimavanserin for the Treatment of Irritability Associated With Autism Spectrum Disorder (NCT05523895) | ACADIA Pharmaceuticals Inc. | 2022-08-09 |
| Copper-64 SAR Bombesin in PSMA Negative Prostate Cancer (BOP) (NCT05613842) | St Vincent's Hospital, Sydney | 2022-08-09 |
| A Trial of SHR0410 Injection in Postsurgical Pain Management (NCT05394402) | Jiangsu HengRui Medicine Co., Ltd. | 2022-08-09 |
| Study of Axicabtagene Ciloleucel Given With Steroids In Participants With Relapsed Or Refractory Large B-Cell Lymphoma (NCT05459571) | Kite, A Gilead Company | 2022-08-09 |
| A Study of CM336 in Patients With Relapsed or Refractory Multiple Myeloma (NCT05299424) | Keymed Biosciences Co.Ltd | 2022-08-09 |
| Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer (NCT04929028) | National Cancer Institute (NCI) | 2022-08-09 |
| 2-HOBA Phase 2 Clinical Trial in Rheumatoid Arthritis (NCT05274243) | Vanderbilt University Medical Center | 2022-08-09 |
| Trial of the Immunogenicity, Safety, and Tolerability of rF1V Vaccine With CpG 1018® Adjuvant Compared With rF1V Vaccine in Adults 18 to 55 Years of Age (NCT05506969) | Dynavax Technologies Corporation | 2022-08-09 |
| Comparative Pharmacokinetics of Two Different Oral Delivery Systems of Cholecalciferol (NCT05104970) | Scotmann Pharmaceuticals | 2022-08-09 |
| Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis (NCT05333471) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-08-08 |
| Neoadjuvant Triprizumab and Radiotherapy in Operable Patients With Stage IIA-IIIA Non-small Cell Lung Cancer (NCT06065813) | Northern Jiangsu People's Hospital | 2022-08-08 |
| TQB3616 Capsules in the Treatment of Dedifferentiated Liposarcoma (NCT05496569) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2022-08-08 |
| A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight (NCT05486065) | Novo Nordisk A/S | 2022-08-08 |
| Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT (NCT04858776) | Mercator MedSystems, Inc. | 2022-08-08 |
| Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients (NCT04948619) | Wake Forest University Health Sciences | 2022-08-08 |
| A Study of Oral EX039 in Subjects with Mild Alzheimer's Disease (NCT05413655) | Excelsior | 2022-08-08 |
| Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer (NCT05254171) | Panbela Therapeutics, Inc. | 2022-08-08 |
| Donepezil and Cognitive Training for Alcohol Use Disorder (AUD) (NCT05042102) | VA Connecticut Healthcare System | 2022-08-08 |
| Study of Fordadistrogene Movaparvovec in Early Stage Duchenne Muscular Dystrophy (NCT05429372) | Pfizer | 2022-08-08 |
| Tofacitinib in the Treatment of Rheumatoid Arthritis-related Interstitial Lung Disease. (NCT05246293) | National Institute of Respiratory Diseases, Mexico | 2022-08-08 |
| An Open-Label Study of Oral NNZ-2591 in Phelan-McDermid Syndrome (PMS-001) (NCT05025241) | Neuren Pharmaceuticals Limited | 2022-08-08 |
| Vyxeos for Induction of Low- or Intermediate-risk. (NCT05599360) | Shaare Zedek Medical Center | 2022-08-07 |
| Adjuvant Furmonertinib in Stage IA With High Risk Factors and Stage IB Non-small Cell Lung Cancer (NCT05445310) | Peking Union Medical College Hospital | 2022-08-06 |
| Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial (NCT05616000) | Khyber Medical University Peshawar | 2022-08-06 |
| Short-course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer (NCT05484024) | Chinese Academy of Medical Sciences | 2022-08-06 |
| Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia (NCT05431543) | LENZ Therapeutics, Inc | 2022-08-06 |
| Pirfenidone Treat Myocardial Fibrosis After Acute Myocardial Infarction (NCT05531955) | Shanghai Zhongshan Hospital | 2022-08-05 |
| Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer (NCT05243524) | ImmunoVaccine Technologies, Inc. (IMV Inc.) | 2022-08-05 |
| A Study of MRG002 in the Treatment of Patients With HER2-expressed Advanced Malignant Solid Tumors. (NCT05338957) | Shanghai Miracogen Inc. | 2022-08-05 |
| The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa (NCT05413148) | TC Erciyes University | 2022-08-05 |
| Dasatinib for the Treatment of Moderate and Severe COVID-19 (NCT04830735) | University of Southern California | 2022-08-05 |
| Modulating Exercise Dosage to Improve Concussion Recovery (NCT05434130) | University of Colorado, Denver | 2022-08-05 |
| Escitalopram to Placebo in Patients With Localized Pancreatic Cancer (NCT05289830) | Case Comprehensive Cancer Center | 2022-08-05 |
| Vitamin E Dosing Study (NCT04801849) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2022-08-05 |
| Efficacy and Safety of S (+) - Ibuprofen in Osteoarthritis Pain (NCT04637529) | Apsen Farmaceutica S.A. | 2022-08-05 |
| A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers (NCT05337735) | M.D. Anderson Cancer Center | 2022-08-05 |
| A Clinical Study of 8MW2311 in Subjects With Locally Advanced or Metastatic Solid Tumors (NCT05416749) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2022-08-05 |
| A Study to Evaluate Lanraplenib (LANRA) in Combination With Gilteritinib in Participants With FLT3-mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) (NCT05028751) | Kronos Bio | 2022-08-05 |
| A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors (NCT05453825) | OncXerna Theraputics, Inc. | 2022-08-05 |