| Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax (NCT05192889) | St. Jude Children's Research Hospital | 2022-08-25 |
| Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer. (NCT05230810) | Criterium, Inc. | 2022-08-25 |
| The KIN-FAST Trial (KIN001 For Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With SARS-CoV-2 (NCT05659459) | Kinarus AG | 2022-08-25 |
| A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCC (NCT05221658) | Shanghai Henlius Biotech | 2022-08-25 |
| Camrelizumab Combined With Chemotherapy and Radiotherapy Perioperative Treatment of Esophageal Gastric Junction Adenocarcinoma (NCT06163729) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2022-08-25 |
| Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuricemia (NCT05574036) | Tanta University | 2022-08-25 |
| Perioperative Pembrolizumab and Lenvatinib in Resectable Hepatocellular Carcinoma (HCC) (NCT05185739) | University College, London | 2022-08-25 |
| A Feasibility and Acceptability Pilot Study Evaluating a Patient-Specific Targeted Intervention Using Patient Navigators or Routine Clinical Care (NCT05488444) | M.D. Anderson Cancer Center | 2022-08-25 |
| A Study Evaluating the Safety and Efficacy of HB0036 in Subjects With Advanced Solid Tumors (NCT05417321) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2022-08-25 |
| Safety and Immunogenicity of Different Formulations of an MF59-Adjuvanted Influenza Vaccine in Older Adults ≥50 Years of Age (NCT05501561) | Seqirus | 2022-08-25 |
| To Evaluate the Efficacy of TQB3823 Combined With Abiraterone and Prednisone in Metastatic Castration-resistant Prostate Cancer Patientsprednisone Acetate Tablets in Patients With Metastatic Castration-resistant Prostate Cancer (NCT05405439) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2022-08-25 |
| A Study to Learn About the Safety of Diranersen (BIIB080) Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age (NCT05399888) | Biogen | 2022-08-24 |
| Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia (NCT05445323) | Lexeo Therapeutics | 2022-08-24 |
| A Study Evaluating the Safety and Efficacy of Neuroprotective Peptide CN-105 Peptide in Patients With Acute Supratentorial Intracerebral Hemorrhage (NCT06255977) | Beijing Tiantan Hospital | 2022-08-24 |
| A Clinical Trial of COVAC-2 in Adults (NCT05209009) | University of Saskatchewan | 2022-08-24 |
| A Trial of Neoadjuvant Therapy in Patients With Newly Diagnosed Glioblastoma (NCT05074992) | University College, London | 2022-08-24 |
| A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Arterial Hypertension (NCT05147805) | Insmed Incorporated | 2022-08-24 |
| Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion (NCT05532735) | Annexin Pharmaceuticals AB | 2022-08-24 |
| Study of AMDX-2011P as a Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy (NCT05542576) | Amydis Inc. | 2022-08-24 |
| Cannabinol Use in Patients With Insomnia Disorder (NCT05344170) | Woolcock Institute of Medical Research | 2022-08-24 |
| Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes (NCT04802161) | National Cancer Institute (NCI) | 2022-08-24 |
| A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety Symptoms (NCT05407064) | Definium Therapeutics US, Inc. | 2022-08-24 |
| Inhibition of Reverse Transcription in Aicardi-Goutières Syndrome (NCT04731103) | University of Edinburgh | 2022-08-24 |
| Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell Carcinoma (NCT05535023) | M.D. Anderson Cancer Center | 2022-08-24 |
| Improvement of Lung and Thoracic Compliance in ARDS Patients in Prone Position by Using Inflatable Air Bag (NCT05515484) | Centre Hospitalier Universitaire, Amiens | 2022-08-23 |
| A Study to Assess the Safety, Tolerability, and Efficacy of Namilumab in Participants With Active Cardiac Sarcoidosis (NCT05351554) | Kinevant Sciences GmbH | 2022-08-23 |
| Sintilimab Combined With Lenvatinib Versus HAIC for Perioperative Treatment of Resectable Primary Hepatocellular Carcinoma (NCT05519410) | Tianjin Medical University Cancer Institute and Hospital | 2022-08-23 |
| The Efficacy of Botulinum Toxin vs. Corticosteroid for the Treatment of Refractory Plantar Fasciitis (NCT05367271) | Western Institute for Veterans Research | 2022-08-23 |
| A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA (NCT05515575) | Memorial Sloan Kettering Cancer Center | 2022-08-23 |
| Effect of Butyrate Supplement on Rheumatoid Arthritis (NCT05576597) | Peking University People's Hospital | 2022-08-23 |
| Stem Cell Study in Osteoarthritis of the Knee and Hip Joints (NCT05507099) | Grigory Karmy | 2022-08-23 |
| Phase 1b/2 Study of Liposomal Annamycin (L-Annamycin) in Subjects With Previously Treated Soft-Tissue Sarcomas (STS) With Pulmonary Metastases (NCT05518526) | Maria Sklodowska-Curie National Research Institute of Oncology | 2022-08-23 |
| Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA] (NCT05536973) | Adverum Biotechnologies, Inc. | 2022-08-23 |
| Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis (NCT05384249) | ACELYRIN Inc. | 2022-08-23 |
| Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD (NCT05186415) | Nemours Children's Clinic | 2022-08-23 |
| A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients (NCT05244057) | Shanghai HEP Pharmaceutical Co., Ltd. | 2022-08-23 |
| A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer (NCT05200442) | University of Chicago | 2022-08-22 |
| Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer (NCT05014776) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2022-08-22 |
| Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers (NCT05539872) | Amphastar Pharmaceuticals, Inc. | 2022-08-22 |
| Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials (NCT05492578) | Sanofi | 2022-08-22 |
| A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB) (NCT04752813) | BPGbio | 2022-08-22 |
| Influence of an Anti-osteoporotic Drug on Healing After Surgical Repair of Chronic Rotator Cuff Lesions of the Shoulder (NCT05677152) | AUVA Traumazentrum Vienna Site UKH Meidling | 2022-08-22 |
| A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age (NCT05496231) | GlaxoSmithKline | 2022-08-22 |
| Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial) (NCT05382208) | Weill Medical College of Cornell University | 2022-08-22 |
| Efficacy of a Self-advocacy Serious Game Intervention (NCT04813276) | University of Pittsburgh | 2022-08-22 |
| TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers (NCT05108870) | University of Chicago | 2022-08-22 |
| Controlled Human Malaria Infection Transmission Model - Phase A (NCT04280692) | University of Oxford | 2022-08-22 |
| Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery (NCT05516953) | Tanta University | 2022-08-22 |
| MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia (NCT05464784) | MediciNova | 2022-08-22 |
| The Present Study Was Conducted to Evaluate Bioceramic Root Repair Material Versus Bio MTA in Revascularization of Immature Young Permenant Teeth. (NCT06630156) | Al-Azhar University | 2022-08-21 |
| Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of Knee (NCT05486026) | Hawler Medical University | 2022-08-20 |
| Lenvatinib Combined With PD-1 Inhibitors as First-line Treatment for Unresectable/Advanced Biliary Tract Carcinoma (NCT05509478) | The First Hospital of Jilin University | 2022-08-20 |
| Melatonin As an Analgesic in Preterm Neonate (NCT05971485) | Ain Shams University | 2022-08-20 |
| Chemotherapy vs Chemoradiotherapy for Post-operative Endometrial Cancer Patients With P53-mutation (NCT05489848) | Fudan University | 2022-08-20 |
| Study of 18F-Thretide PET/CT in Patients With Prostate Cancer (NCT05516329) | First Affiliated Hospital of Fujian Medical University | 2022-08-20 |
| Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES) (NCT05068232) | University of Chicago | 2022-08-19 |
| Utidelone Combined With Bevacizumab in the Treatment of ≥ 2 Lines of HER-2 Negative Advanced Breast Cancer (NCT05398861) | Henan Cancer Hospital | 2022-08-19 |
| A Phase II Randomized Controlled Trial to Determine the Efficacy of an auGmented reAlity gaMe in pediatrIc caNcer Patients Who Are Opioid Naïve Undergoing Surgery to Reduce Postoperative Opioid Use (GAMING-ON Study) (NCT05466994) | M.D. Anderson Cancer Center | 2022-08-19 |
| An Efficacy and Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy in Chinese Participants With Acute Myeloid Leukemia in Complete Remission (NCT05413018) | Bristol-Myers Squibb | 2022-08-19 |
| A Clinical Study to Evaluate the Efficacy and Safety of SIM0417 Orally Co-Administered With Ritonavir in Symptomatic Adult Participants With Mild to Moderate COVID-19 (NCT05506176) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2022-08-19 |
| Safety and Immunogenicity of COVID-19 Vaccine, AdCLD-CoV19-1 (NCT05520970) | Cellid Co., Ltd. | 2022-08-19 |
| The Role of Simvastatin in the Epithelial-Mesenchymal Transition Process of Breast Cancer (NCT05550415) | Indonesia University | 2022-08-19 |
| Efficacy of Pulmozyme® on Arterial Recanalization in Post-thrombectomy Patients Managed for Ischemic Stroke (NETs-target) (NCT04785066) | Fondation Ophtalmologique Adolphe de Rothschild | 2022-08-19 |
| A Phase 1/2 Study to Evaluate OTX-2002 in Patients with Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association with the MYC Oncogene (NCT05497453) | Omega Therapeutics | 2022-08-19 |
| Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis (NCT05374590) | argenx | 2022-08-18 |
| Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma (NCT05155033) | National Cancer Institute (NCI) | 2022-08-18 |
| Randomized and Open Label Study for Safety and Efficacy of DBI-102 vs. Vehicle vs. Hydroquinone on Skin Pigmentation and Lentigos (NCT05511948) | DermBiont, Inc. | 2022-08-18 |
| Relapsed or Refractory Primary Diffuse Large B-cell Lymphoma (DLBCL) of the Central Nervous System (CNS) (NCT05253118) | Seoul National University Hospital | 2022-08-18 |
| A Study of Docetaxel for Injection (Albumin-bound) in Combination With Bevacizumab in Patients With Ovarian Cancer (NCT05325229) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2022-08-18 |
| JAB-BX102 Monotherapy and Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors (NCT05174585) | Jacobio Pharmaceuticals Co., Ltd. | 2022-08-18 |
| Donafenib Plus Sintilimab in Combination With TACE in Patients With Unresectable Hepatocellular Carcinoma (NCT05507632) | Nanfang Hospital, Southern Medical University | 2022-08-18 |
| Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test (NCT05243641) | M.D. Anderson Cancer Center | 2022-08-18 |
| Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors (NCT04925609) | Princess Maxima Center for Pediatric Oncology | 2022-08-18 |
| A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 Infection (NCT05472090) | Tonix Pharmaceuticals, Inc. | 2022-08-18 |
| Tebipenem Trial in Children With Shigellosis (NCT05121974) | International Centre for Diarrhoeal Disease Research, Bangladesh | 2022-08-18 |
| A Study to Evaluate the Safety and Efficacy of Multiple Doses of LT3001 Drug Product in AIS Subjects (NCT05403866) | Lumosa Therapeutics Co., Ltd. | 2022-08-17 |
| A Study of IMU-131 (HER-Vaxx) in Combination With Chemotherapy or Pembrolizumab in Patients With Metastatic HER2/Neu Over-Expressing Gastric Cancer (nextHERIZON) (NCT05311176) | Imugene Limited | 2022-08-17 |
| A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley) (NCT05327530) | EMD Serono Research & Development Institute, Inc. | 2022-08-17 |
| Radioembolization of Metastatic Breast Cancer to the Liver as a 2nd/3rd Line Therapy (NCT05315687) | Emory University | 2022-08-17 |
| SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer (NCT05445908) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2022-08-17 |
| A Study of Ensartinib as Neoadjuvant Therapy for Patients With ALK Positive Resectable Non-Small Cell Lung Cancer (NCT05380024) | Peking University Cancer Hospital & Institute | 2022-08-17 |
| A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic Follicular Lymphoma (NCT05451810) | Genmab | 2022-08-17 |
| A Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis (NCT05470647) | Beijing Tongren Hospital | 2022-08-17 |
| A Phase I/II Dose Escalation and Expansion Study of BST-236 Plus Venetoclax in Patients With Unfit Newly Diagnosed AML (NCT05503355) | BioSight Ltd. | 2022-08-17 |
| A Study to Assess the Role of Fenofibrate in Preventing Ischemic Cholangiopathy After Liver Transplantation (NCT05514119) | Mayo Clinic | 2022-08-17 |
| Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D) (NCT05731544) | Biomea Fusion Inc. | 2022-08-17 |
| A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1 (NCT05276726) | Allist Pharmaceuticals, Inc. | 2022-08-17 |
| A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM) (NCT05403476) | Ferring Pharmaceuticals | 2022-08-16 |
| Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) (NCT05322850) | University of Florida | 2022-08-16 |
| A Study to Explore Pamiparib Treatment in Epithelial Ovarian Cancer After Prior PARP Inhibitor Exposure (NCT05489926) | Zhejiang Cancer Hospital | 2022-08-16 |
| Phase 2 Spectra Study to Evaluate the Safety and Efficacy of OPL-0401 in Patients With Diabetic Retinopathy (NCT05393284) | Valo Health, Inc. | 2022-08-16 |
| Obese Human Beta-2-adrenergic Stimulation and Muscle Glucose Uptake (NCT04921306) | Maastricht University | 2022-08-16 |
| A Phase II Clinical Study of Surufatinib Combined With Sintilimab in the Treatment of Advanced Gastric Cancer (NCT05235906) | Sun Yat-sen University | 2022-08-16 |
| Study Assessing QBS72S For Treating Brain Metastases (NCT05305365) | Stanford University | 2022-08-16 |
| DON in Pediatric Cerebral Malaria (NCT05478720) | Douglas Postels, MD, MS | 2022-08-16 |
| Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (NCT05502341) | Gilead Sciences | 2022-08-16 |
| The Effect of Oral Nanocurcumin as an Adjuvant Therapy for Anogenital Warts: Evaluation of Clinical Improvement, NFĸB, IFN-γ, and FOXP3+TReg From Lesions Tissue (NCT06281353) | Indonesia University | 2022-08-16 |
| Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001 (NCT05254327) | University of Nebraska | 2022-08-15 |
| Effectiveness of Aquamin® in Mitigating Halitosis (NCT05058638) | University of Michigan | 2022-08-15 |
| Cardiometabolic Effects of Pecans as a Snack (NCT05071807) | Penn State University | 2022-08-15 |